Jonathan E Golub
Biographic Data
| ID | 1948594 |
|---|---|
| NAME | Jonathan E Golub |
| GIVEN NAMES | Jonathan E |
| FAMILY NAME | Golub |
| SIGNATURE | GOLUB J E |
| AFFILIATIONS | Johns Hopkins University |
| ORCID | 0000-0003-2398-3145 |
| VERIFIED | Yes |
| TOTAL WORKS | 35 |
| TOTAL CITATIONS | 376 |
| AUTHOR COUNT | 35 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1996 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 10 |
Frontline healthcare worker barriers impacting tuberculosis service demand and access in high burden settings
Background: Extensive literature exists on health-seeking behaviour and barriers related to the uptake of tuberculosis (TB)-related services in high TB burden settings. However, prior reviews have focused on patient- and health facility/systems-level barriers to TB-related care. In this scoping review, we aimed to synthesise frontline healthcare worker (FLHCW)-related barriers that limit individuals' demand for, access to, and retention in TB ser…
The implementation of tuberculosis preventive therapy in HIV care clinics in Africa, Asia and Latin America
INTRODUCTION: Towards the 'End TB Strategy' targets, the WHO recommends the provision of tuberculosis (TB) preventive therapy (TPT) for high-risk groups including people living with HIV (PLWH). 3 years after the release of the updated 2020 WHO guidelines, we investigated the implementation of TPT services at HIV clinics in low-income and middle-income countries (LMICs), focusing on TB screening, populations eligible for TPT and available TPT regi…
Repeat Behavioral Counseling, With and Without Combination Nicotine Replacement Therapy, for Smoking Cessation Among People With HIV in South Africa
Designing integrated care models for mental health and tuberculosis in Pune, India
People with tuberculosis (TB) and TB survivors are at increased risk for mental health (MH) conditions. Better management of conditions like depression can improve adherence to TB treatment, and integrating MH care into TB treatment may reduce the MH treatment gap and improve outcomes. This qualitative study explored design characteristics for integrated MH-TB care in Pune, India. Data collection involved in-depth interviews (n = 25) with TB surv…
An evaluation of a choice architecture-based intervention on prescribing of TB preventive treatment to people living with HIV in southern Africa (the CAT study)
INTRODUCTION: While highly effective for reducing the risk of tuberculosis (TB) disease, TB preventive treatment (TPT) is underused among people living with HIV (PWH). We evaluated the effectiveness of a behavioural economics-based choice architecture approach to increase facility-level TPT prescribing to PWH in Malawi, Mozambique and Zimbabwe. METHODS: We conducted a cluster-randomised trial within the IMPAACT4TB 3HP rollout, in which 57 healthc…
Fighting tuberculosis hand in hand
Tuberculosis (TB) is an infectious disease closely intertwined with stigma, discrimination, and the social determinants of health. Communities of people affected by TB are experts in their care pathways, but the TB field continues to fall short of meaningfully engaging communities in TB research. This is a missed opportunity to improve the quality, relevance, person-centeredness, positive impact, and sustainability of TB research outputs. We ackn…
Cost and cost-effectiveness of pediatric home-based versus facility-based TB Preventive Treatment in Ethiopia (CHIP-TB)
Tuberculosis preventive treatment (TPT) is an essential intervention recommended for all child contacts in Ethiopia under 15 years who are at risk of tuberculosis (TB) infection. We conducted a cost and cost-effectiveness analysis of home-based versus facility-based TPT provision for child contacts in Ethiopia. As part of the CHIP TB trial, a pragmatic, cluster-randomized trial conducted at eighteen clinics in Ethiopia, clinics were randomized to…
The Nicotine Metabolite Ratio and Response to Smoking Cessation Treatment Among People Living with HIV Who Smoke in South Africa
The nicotine metabolite ratio (NMR) has been informative in selecting treatment choices for nicotine dependence and increasing treatment efficacy in Western settings; however, the clinical utility of the NMR among smokers in low-resource settings remains unclear. Prospective analysis was conducted using data from a randomized controlled trial of smoking cessation among adults living with HIV, to examine the association between the NMR and respons…
Contextualizing and optimizing novel strategies to improve the latent TB continuum of care
Tuberculosis (TB) causes 1 in 3 deaths among people living with HIV (PLHIV). Diagnosing and treating latent tuberculosis infection (LTBI) is critical to reducing TB incidence and mortality. Blood-based screening tests (e.g., QuantiFERON-TB Gold Plus (QFT+)) and shorter-course TB preventive therapy (TPT) regimens such as 3HP (3 months weekly isoniazid-rifapentine) hold significant promise to improve TB outcomes. We qualitatively explored barriers …
A Cross-Sectional Analysis of the Nicotine Metabolite Ratio and Its Association with Sociodemographic and Smoking Characteristics among People with HIV Who Smoke in South Africa
The nicotine metabolite ratio (NMR) is associated with race/ethnicity but has not been evaluated among smokers in the African region. We conducted a cross-sectional analysis of baseline data from a large randomized, controlled trial for smoking cessation among people with HIV (PWH) in South Africa. Urine samples were analyzed for the NMR and evaluated as a binary variable using a cutoff value of the fourth quartile to determine the fastest metabo…
Do community-based active case-finding interventions have indirect impacts on wider TB case detection and determinants of subsequent TB testing behaviour? A systematic review
Community-based active case-finding (ACF) may have important impacts on routine TB case-detection and subsequent patient-initiated diagnosis pathways, contributing “indirectly” to infectious diseases prevention and care. We investigated the impact of ACF beyond directly diagnosed patients for TB, using routine case-notification rate (CNR) ratios as a measure of indirect effect. We systematically searched for publications 01-Jan-1980 to 13-Apr-202…
Improving Analyses of Sanctions Busting
When economic sanctions are directed against a target state by a sender state, the sender obviously wants third countries to participate with the sanctions and can apply pressure on them to prevent sanctions busting behaviour. But why does sanctions busting vary, so that the target’s trade with some third-countries increases but with others decreases? In this paper I offer two improvements to the analysis of sanctions busting: a theoretical frame…
Formative research for an mHealth program to improve the HIV care continuum in South Africa
In South Africa, high attrition rates throughout the care continuum present major barriers to controlling the HIV epidemic. Mobile health (mHealth) interventions may provide innovative opportunities for efficient healthcare delivery and improving retention in care. In this formative research, we interviewed 11 patients and 28 healthcare providers in North West Province, South Africa, to identify perceived benefits, concerns and suggestions for a …
Secure Delivery of HIV-Related and Tuberculosis Laboratory Results to Patient Cell Phones
Power in the European Union
Even the best existing model of legislative decisionmaking in the European Union, the compromise model, makes huge prediction errors when it is assumed that each actor’s power is determined by their formal voting weight. A few studies have attempted to improve the model’s predictive accuracy by examining alternative distributions of power, but extending their brute force approach poses daunting computational challenges. In this paper I illustrate…
Civil Conflict and Agenda-Setting Speed in the United Nations Security Council
The United Nations Security Council (UNSC) can respond to a civil conflict only if that conflict first enters the Council's agenda. Some conflicts reach the Council's agenda within days after they start, others after years (or even decades), and some never make it. So far, only a few studies have looked at the crucial UNSC agenda-setting stage, and none have examined agenda-setting speed. To fill this important gap, we develop and test a novel th…
Promoting Tuberculosis Preventive Therapy for People Living with HIV in South Africa
The effect of partner HIV status on motivation to take antiretroviral and isoniazid preventive therapies
Antiretroviral therapy (ART) and isoniazid preventive therapy (IPT) are important to reduce morbidity and mortality among people newly diagnosed of HIV. The successful uptake of ART and IPT requires a comprehensive understanding of patients' motivation to take such therapies. Partners also play an important role in the decision to be initiated and retained in care. We quantified patients' motivation to take preventive therapies (ART and IPT) and …
Modelling the impact of social protection on tuberculosis
Results are to be confirmed with further analysis. However, by developing a generalizable modelling framework, S-PROTECT proved that the modelling of social protection is complex, but doable and allowed to draw the research road map for the future in this field
Maternal Motivation to Take Preventive Therapy in Antepartum and Postpartum Among HIV-Positive Pregnant Women in South Africa
Inequalities in Haart uptake and differential survival according to exposure category in Rio de Janeiro, Brazil
Despite substantial improvement in prognosis and quality of life among people living with HIV/AIDS (PLWHA) in Brazil, inequalities in access to treatment remain. We assessed the impact of these inequalities on survival in Rio de Janeiro over a 12-year period (2000/11). Data were merged from four databases that comprise the national AIDS monitoring system: SINAN-AIDS (Brazilian Information System for Notificable Diseases; AIDS cases), SISCEL (labo…
Postarrival Tuberculosis Screening of High-Risk Immigrants at a Local Health Department
Objectives. We sought to characterize postimmigration tuberculosis (TB) care for Class B immigrants and refugees at the Baltimore City Health Department TB program (BCHD), and to determine the proportion of immigrants with active TB or latent TB infection (LTBI) in this high-risk population. Methods. We conducted a retrospective chart review of Class B immigrants and refugees who reported to the BCHD for postimmigration TB evaluation from 2010 to…
Analysis of Latent Tuberculosis Infection Treatment Adherence Among Refugees and Other Patient Groups Referred to the Baltimore City Health Department TB Clinic, February 2009–March 2011
How the European Union does not work
We know surprisingly little about whether the content of European Union legislation reflects the preferences of some Member States more than others. The few studies that have examined national bargaining success rates for EU legislation have conceptual and methodological weaknesses. To redress these problems I use a salience-weighted measure to gauge the relative success of Member States in translating their national preferences into legislation,…
Cheap dates and the delusion of gratification
Each year, small Member States receive a disproportionate share of the European Union's (EU's) budget. A prominent explanation for this is that Council decision-making involves a healthy dose of vote selling, whereby large Member States offer small states generous fiscal transfers in exchange for influence over policy. But nobody has investigated whether net budget contributors actually get anything for their money. In this paper I identify the v…
In the Shadow of the Vote? Decision Making in the European Community
Scholarship on the European Community (EC) focuses particular attention on how formal voting rules and institutional reform condition decision-making outcomes. The predominant view of EC history holds that decision making remained paralyzed until institutional reforms in 1987 and 1992 restored and expanded adherence to majority voting rules, which in turn unblocked and expedited EC legislative efforts. In this study I challenge these fundamental …
Survival Analysis and European Union Decision-making
Practitioners as well as scholars of European integration have for decades debated why it takes so long for the European Union (EU) to adopt legislation and how to improve decision-making efficiency. Four studies have investigated decision-making speed using survival analysis, a particularly appropriate quantitative technique. In this paper I show that all four studies suffer from serious methodological problems that render their conclusions unre…
How the European Union does not work
We know surprisingly little about whether the content of European Union legislation reflects the preferences of some Member States more than others. The few studies that have examined national bargaining success rates for EU legislation have conceptual and methodological weaknesses. To redress these problems I use a salience-weighted measure to gauge the relative success of Member States in translating their national preferences into legislation,…
How Time Affects EU Decision-Making
International audience
The politics of judicial discretion
The recognition that courts play a significant role in the process of European integration has focused attention on the interaction between national judges and the European Court of Justice. The prevailing theoretical model of this interaction holds that a variety of incentives impel national judges to co‐operate with the ECJ by providing it with frequent preliminary references. This article tests the ability of the model to account for the behav…
The Study of Decision-Making Speed in the European Union
The study of European Union (EU) decision-making speed holds both substantive and theoretical importance.Substantively, it helps identify which factors produce or avert legislative paralysis, an insight that is a necessary precondition for informed debate about potential EU institutional reforms.Indeed, I entered this field in 1994 while at the European University Institute in Florence to test whether the reforms contained in the famous 1987 Sing…
Sovereignty and Subsidiarity in EU Environmental Policy
This article explores the connection between the subsidiarity principle and national sovereignty in the context of EU environmental policy. In addition to providing an historical account of this connection, the article suggests that subsidiarity represents a Janus-faced concept capable of either supporting or undermining the legitimacy of EU environmental policy. By developing explicit criteria by which to apply subsidiarity, a number of areas ar…
State Power and Institutional Influence in European Integration
This study traces the development of the recently adopted packaging waste directive in order to illuminate the role of various actors in the integration process. While some of the findings about agenda‐setting and qualified majority voting presented in this study apply directly to the sector of environmental policy, or specifically to the chosen case, the broader conclusions suggest the need for additional case studies of EC legislation and offer…
Civil Conflict and Agenda-Setting Speed in the United Nations Security Council
The United Nations Security Council (UNSC) can respond to a civil conflict only if that conflict first enters the Council's agenda. Some conflicts reach the Council's agenda within days after they start, others after years (or even decades), and some never make it. So far, only a few studies have looked at the crucial UNSC agenda-setting stage, and none have examined agenda-setting speed. To fill this important gap, we develop and test a novel th…
Transnational Politics of the Environment
Transnational Politics of the Environment: The European Union and Environmental Policy in Central and Eastern Europe. By Liliana Andonova. Cambridge, MA: The MIT Press, 2004. 224p. $57.00 cloth, $23.00 paper. After the collapse of communism at the end of the 1980s, the 10 new emerging democracies in Central and Eastern Europe (CEE) all sought to accede to the European Union. But to join the EU, applicant countries had first to adopt the vast arra…
Cheap dates and the delusion of gratification
Each year, small Member States receive a disproportionate share of the European Union's (EU's) budget. A prominent explanation for this is that Council decision-making involves a healthy dose of vote selling, whereby large Member States offer small states generous fiscal transfers in exchange for influence over policy. But nobody has investigated whether net budget contributors actually get anything for their money. In this paper I identify the v…
Power in the European Union
Even the best existing model of legislative decisionmaking in the European Union, the compromise model, makes huge prediction errors when it is assumed that each actor’s power is determined by their formal voting weight. A few studies have attempted to improve the model’s predictive accuracy by examining alternative distributions of power, but extending their brute force approach poses daunting computational challenges. In this paper I illustrate…
Cost-effectiveness of community health worker versus home-based guardians for directly observed treatment of tuberculosis in Vitória, Espírito Santo State, Brazil
The objective of this study was to compare the costs and outcomes associated with guardian-supervised directly observed treatment relative to the standard of care Directly Observed Therapy, Short Course (DOTS) provided by community health workers (CHW). New cases of culture-positive pulmonary tuberculosis (TB) treated in Vitória, Espírito Santo State, Brazil, between January 2005 and December 2006 were interviewed and chose their preferred treatm…
British sovereignty and the development of EC environmental policy
Functionalist models of integration and the emergence of a global environmental movement do not explain the development of European Community environmental policy because they fail to focus on the role of individual member states in shaping the actual content of EC environmental policies. For its part, the British government agreed to environmental directives because it believed that they would not undermine its sovereignty ‐ the ability to pursu…
The politics of judicial discretion
The recognition that courts play a significant role in the process of European integration has focused attention on the interaction between national judges and the European Court of Justice. The prevailing theoretical model of this interaction holds that a variety of incentives impel national judges to co‐operate with the ECJ by providing it with frequent preliminary references. This article tests the ability of the model to account for the behav…
State Power and Institutional Influence in European Integration
This study traces the development of the recently adopted packaging waste directive in order to illuminate the role of various actors in the integration process. While some of the findings about agenda‐setting and qualified majority voting presented in this study apply directly to the sector of environmental policy, or specifically to the chosen case, the broader conclusions suggest the need for additional case studies of EC legislation and offer…
Sovereignty and Subsidiarity in EU Environmental Policy
This article explores the connection between the subsidiarity principle and national sovereignty in the context of EU environmental policy. In addition to providing an historical account of this connection, the article suggests that subsidiarity represents a Janus-faced concept capable of either supporting or undermining the legitimacy of EU environmental policy. By developing explicit criteria by which to apply subsidiarity, a number of areas ar…
British sovereignty and the development of EC environmental policy
Functionalist models of integration and the emergence of a global environmental movement do not explain the development of European Community environmental policy because they fail to focus on the role of individual member states in shaping the actual content of EC environmental policies. For its part, the British government agreed to environmental directives because it believed that they would not undermine its sovereignty ‐ the ability to pursu…
In the Shadow of the Vote? Decision Making in the European Community
Scholarship on the European Community (EC) focuses particular attention on how formal voting rules and institutional reform condition decision-making outcomes. The predominant view of EC history holds that decision making remained paralyzed until institutional reforms in 1987 and 1992 restored and expanded adherence to majority voting rules, which in turn unblocked and expedited EC legislative efforts. In this study I challenge these fundamental …
Transnational Politics of the Environment
Transnational Politics of the Environment: The European Union and Environmental Policy in Central and Eastern Europe. By Liliana Andonova. Cambridge, MA: The MIT Press, 2004. 224p. $57.00 cloth, $23.00 paper. After the collapse of communism at the end of the 1980s, the 10 new emerging democracies in Central and Eastern Europe (CEE) all sought to accede to the European Union. But to join the EU, applicant countries had first to adopt the vast arra…
Survival Analysis and European Union Decision-making
Practitioners as well as scholars of European integration have for decades debated why it takes so long for the European Union (EU) to adopt legislation and how to improve decision-making efficiency. Four studies have investigated decision-making speed using survival analysis, a particularly appropriate quantitative technique. In this paper I show that all four studies suffer from serious methodological problems that render their conclusions unre…
How Time Affects EU Decision-Making
International audience
The Study of Decision-Making Speed in the European Union
The study of European Union (EU) decision-making speed holds both substantive and theoretical importance.Substantively, it helps identify which factors produce or avert legislative paralysis, an insight that is a necessary precondition for informed debate about potential EU institutional reforms.Indeed, I entered this field in 1994 while at the European University Institute in Florence to test whether the reforms contained in the famous 1987 Sing…
Cost-effectiveness of community health worker versus home-based guardians for directly observed treatment of tuberculosis in Vitória, Espírito Santo State, Brazil
The objective of this study was to compare the costs and outcomes associated with guardian-supervised directly observed treatment relative to the standard of care Directly Observed Therapy, Short Course (DOTS) provided by community health workers (CHW). New cases of culture-positive pulmonary tuberculosis (TB) treated in Vitória, Espírito Santo State, Brazil, between January 2005 and December 2006 were interviewed and chose their preferred treatm…
How the European Union does not work
We know surprisingly little about whether the content of European Union legislation reflects the preferences of some Member States more than others. The few studies that have examined national bargaining success rates for EU legislation have conceptual and methodological weaknesses. To redress these problems I use a salience-weighted measure to gauge the relative success of Member States in translating their national preferences into legislation,…
Cheap dates and the delusion of gratification
Each year, small Member States receive a disproportionate share of the European Union's (EU's) budget. A prominent explanation for this is that Council decision-making involves a healthy dose of vote selling, whereby large Member States offer small states generous fiscal transfers in exchange for influence over policy. But nobody has investigated whether net budget contributors actually get anything for their money. In this paper I identify the v…
Analysis of Latent Tuberculosis Infection Treatment Adherence Among Refugees and Other Patient Groups Referred to the Baltimore City Health Department TB Clinic, February 2009–March 2011
Postarrival Tuberculosis Screening of High-Risk Immigrants at a Local Health Department
Objectives. We sought to characterize postimmigration tuberculosis (TB) care for Class B immigrants and refugees at the Baltimore City Health Department TB program (BCHD), and to determine the proportion of immigrants with active TB or latent TB infection (LTBI) in this high-risk population. Methods. We conducted a retrospective chart review of Class B immigrants and refugees who reported to the BCHD for postimmigration TB evaluation from 2010 to…
The effect of partner HIV status on motivation to take antiretroviral and isoniazid preventive therapies
Antiretroviral therapy (ART) and isoniazid preventive therapy (IPT) are important to reduce morbidity and mortality among people newly diagnosed of HIV. The successful uptake of ART and IPT requires a comprehensive understanding of patients' motivation to take such therapies. Partners also play an important role in the decision to be initiated and retained in care. We quantified patients' motivation to take preventive therapies (ART and IPT) and …
Modelling the impact of social protection on tuberculosis
Results are to be confirmed with further analysis. However, by developing a generalizable modelling framework, S-PROTECT proved that the modelling of social protection is complex, but doable and allowed to draw the research road map for the future in this field
Maternal Motivation to Take Preventive Therapy in Antepartum and Postpartum Among HIV-Positive Pregnant Women in South Africa
Inequalities in Haart uptake and differential survival according to exposure category in Rio de Janeiro, Brazil
Despite substantial improvement in prognosis and quality of life among people living with HIV/AIDS (PLWHA) in Brazil, inequalities in access to treatment remain. We assessed the impact of these inequalities on survival in Rio de Janeiro over a 12-year period (2000/11). Data were merged from four databases that comprise the national AIDS monitoring system: SINAN-AIDS (Brazilian Information System for Notificable Diseases; AIDS cases), SISCEL (labo…
Promoting Tuberculosis Preventive Therapy for People Living with HIV in South Africa
Improving Analyses of Sanctions Busting
When economic sanctions are directed against a target state by a sender state, the sender obviously wants third countries to participate with the sanctions and can apply pressure on them to prevent sanctions busting behaviour. But why does sanctions busting vary, so that the target’s trade with some third-countries increases but with others decreases? In this paper I offer two improvements to the analysis of sanctions busting: a theoretical frame…
Formative research for an mHealth program to improve the HIV care continuum in South Africa
In South Africa, high attrition rates throughout the care continuum present major barriers to controlling the HIV epidemic. Mobile health (mHealth) interventions may provide innovative opportunities for efficient healthcare delivery and improving retention in care. In this formative research, we interviewed 11 patients and 28 healthcare providers in North West Province, South Africa, to identify perceived benefits, concerns and suggestions for a …
Secure Delivery of HIV-Related and Tuberculosis Laboratory Results to Patient Cell Phones
Power in the European Union
Even the best existing model of legislative decisionmaking in the European Union, the compromise model, makes huge prediction errors when it is assumed that each actor’s power is determined by their formal voting weight. A few studies have attempted to improve the model’s predictive accuracy by examining alternative distributions of power, but extending their brute force approach poses daunting computational challenges. In this paper I illustrate…
Civil Conflict and Agenda-Setting Speed in the United Nations Security Council
The United Nations Security Council (UNSC) can respond to a civil conflict only if that conflict first enters the Council's agenda. Some conflicts reach the Council's agenda within days after they start, others after years (or even decades), and some never make it. So far, only a few studies have looked at the crucial UNSC agenda-setting stage, and none have examined agenda-setting speed. To fill this important gap, we develop and test a novel th…
Do community-based active case-finding interventions have indirect impacts on wider TB case detection and determinants of subsequent TB testing behaviour? A systematic review
Community-based active case-finding (ACF) may have important impacts on routine TB case-detection and subsequent patient-initiated diagnosis pathways, contributing “indirectly” to infectious diseases prevention and care. We investigated the impact of ACF beyond directly diagnosed patients for TB, using routine case-notification rate (CNR) ratios as a measure of indirect effect. We systematically searched for publications 01-Jan-1980 to 13-Apr-202…
Medicine (16 works) · Economics (15 works) · Political science (15 works) · Law (13 works) · Tuberculosis (12 works) · European Union Policy and Governance (11 works) · Law (11 works) · Tuberculosis Research and Epidemiology (11 works) · European union (10 works) · Family medicine (9 works)