Frederick S Barrett
Biographic Data
| ID | 1971696 |
|---|---|
| NAME | Frederick S Barrett |
| GIVEN NAMES | Frederick S |
| FAMILY NAME | Barrett |
| SIGNATURE | BARRETT F S |
| AFFILIATIONS | Johns Hopkins University |
| ORCID | 0000-0001-7443-3237 |
| VERIFIED | Yes |
| TOTAL WORKS | 12 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 12 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2010 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Mystical dynamics
Five-year outcomes of psilocybin-assisted therapy for Major Depressive Disorder
BackgroundMajor Depressive Disorder (MDD) is a leading cause of disability and economic loss, with high recurrence and treatment resistance. Psilocybin-assisted therapy (PAT) shows promise in reducing depressive symptoms, but long-term effects are unknown. We aimed to determine the long-term safety and efficacy of PAT for MDD over a five-year follow-up period.MethodsIndividuals who previously participated in an RCT studying the effects of PAT for…
Naturalistic psilocybin use is associated with persisting improvements in mental health and wellbeing
Results from this study, the largest prospective survey of naturalistic psilocybin use to date, support the potential for psilocybin to produce lasting improvements in mental health symptoms and general wellbeing
Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT03181529.
Classic psychedelics
Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety
Psilocybin-occasioned mystical-type experience in combination with meditation and other spiritual practices produces enduring positive changes in psychological functioning and in trait measures of pro…
Psilocybin can occasion mystical-type experiences with participant-attributed increases in well-being. However, little research has examined enduring changes in traits. This study administered psilocybin to participants who undertook a program of meditation/spiritual practices. Healthy participants were randomized to three groups (25 each): (1) very low-dose (1 mg/70 kg on sessions 1 and 2) with moderate-level (“standard”) support for spiritual-p…
Classic Hallucinogens and Mystical Experiences
Survey study of challenging experiences after ingesting psilocybin mushrooms
Acute and enduring adverse effects of psilocybin have been reported anecdotally, but have not been well characterized. For this study, 1993 individuals (mean age 30 yrs; 78% male) completed an online survey about their single most psychologically difficult or challenging experience (worst “bad trip”) after consuming psilocybin mushrooms. Thirty-nine percent rated it among the top five most challenging experiences of his/her lifetime. Eleven perce…
The Challenging Experience Questionnaire
Acute adverse psychological reactions to classic hallucinogens (“bad trips” or “challenging experiences”), while usually benign with proper screening, preparation, and support in controlled settings, remain a safety concern in uncontrolled settings (such as illicit use contexts). Anecdotal and case reports suggest potential adverse acute symptoms including affective (panic, depressed mood), cognitive (confusion, feelings of losing sanity), and so…
Validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin
The 30-item revised Mystical Experience Questionnaire (MEQ30) was previously developed within an online survey of mystical-type experiences occasioned by psilocybin-containing mushrooms. The rated experiences occurred on average eight years before completion of the questionnaire. The current paper validates the MEQ30 using data from experimental studies with controlled doses of psilocybin. Data were pooled and analyzed from five laboratory experi…
Music-evoked nostalgia
Participants listened to randomly selected excerpts of popular music and rated how nostalgic each song made them feel. Nostalgia was stronger to the extent that a song was autobiographically salient, arousing, familiar, and elicited a greater number of positive, negative, and mixed emotions. These effects were moderated by individual differences (nostalgia proneness, mood state, dimensions of the Affective Neurosciences Personality Scale, and fac…
No prominent works on this page.
Music-evoked nostalgia
Participants listened to randomly selected excerpts of popular music and rated how nostalgic each song made them feel. Nostalgia was stronger to the extent that a song was autobiographically salient, arousing, familiar, and elicited a greater number of positive, negative, and mixed emotions. These effects were moderated by individual differences (nostalgia proneness, mood state, dimensions of the Affective Neurosciences Personality Scale, and fac…
Validation of the revised Mystical Experience Questionnaire in experimental sessions with psilocybin
The 30-item revised Mystical Experience Questionnaire (MEQ30) was previously developed within an online survey of mystical-type experiences occasioned by psilocybin-containing mushrooms. The rated experiences occurred on average eight years before completion of the questionnaire. The current paper validates the MEQ30 using data from experimental studies with controlled doses of psilocybin. Data were pooled and analyzed from five laboratory experi…
Survey study of challenging experiences after ingesting psilocybin mushrooms
Acute and enduring adverse effects of psilocybin have been reported anecdotally, but have not been well characterized. For this study, 1993 individuals (mean age 30 yrs; 78% male) completed an online survey about their single most psychologically difficult or challenging experience (worst “bad trip”) after consuming psilocybin mushrooms. Thirty-nine percent rated it among the top five most challenging experiences of his/her lifetime. Eleven perce…
The Challenging Experience Questionnaire
Acute adverse psychological reactions to classic hallucinogens (“bad trips” or “challenging experiences”), while usually benign with proper screening, preparation, and support in controlled settings, remain a safety concern in uncontrolled settings (such as illicit use contexts). Anecdotal and case reports suggest potential adverse acute symptoms including affective (panic, depressed mood), cognitive (confusion, feelings of losing sanity), and so…
Classic Hallucinogens and Mystical Experiences
Psilocybin-occasioned mystical-type experience in combination with meditation and other spiritual practices produces enduring positive changes in psychological functioning and in trait measures of pro…
Psilocybin can occasion mystical-type experiences with participant-attributed increases in well-being. However, little research has examined enduring changes in traits. This study administered psilocybin to participants who undertook a program of meditation/spiritual practices. Healthy participants were randomized to three groups (25 each): (1) very low-dose (1 mg/70 kg on sessions 1 and 2) with moderate-level (“standard”) support for spiritual-p…
Classic psychedelics
Psychological flexibility mediates the relations between acute psychedelic effects and subjective decreases in depression and anxiety
Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder
ClinicalTrials.gov Identifier: NCT03181529.
Naturalistic psilocybin use is associated with persisting improvements in mental health and wellbeing
Results from this study, the largest prospective survey of naturalistic psilocybin use to date, support the potential for psilocybin to produce lasting improvements in mental health symptoms and general wellbeing
Five-year outcomes of psilocybin-assisted therapy for Major Depressive Disorder
BackgroundMajor Depressive Disorder (MDD) is a leading cause of disability and economic loss, with high recurrence and treatment resistance. Psilocybin-assisted therapy (PAT) shows promise in reducing depressive symptoms, but long-term effects are unknown. We aimed to determine the long-term safety and efficacy of PAT for MDD over a five-year follow-up period.MethodsIndividuals who previously participated in an RCT studying the effects of PAT for…
Mystical dynamics
Psychedelics and Drug Studies (11 works) · Psychiatry (10 works) · Psychology (10 works) · Clinical Psychology (9 works) · Psilocybin (9 works) · Hallucinogen (8 works) · Chemical synthesis and alkaloids (6 works) · Medicine (5 works) · Anxiety (4 works) · Complementary and Alternative Medicine Studies (4 works)