Raisa N Zakharova
Biographic Data
| ID | 212928 |
|---|---|
| NAME | Raisa N Zakharova |
| GIVEN NAMES | Raisa N |
| FAMILY NAME | Zakharova |
| SIGNATURE | ZAKHAROVA R N |
| AFFILIATIONS | North-Eastern Federal University |
| ORCID | 0000-0002-1395-8256 |
| VERIFIED | Yes |
| TOTAL WORKS | 6 |
| TOTAL CITATIONS | 9 |
| AUTHOR COUNT | 6 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2018 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
C-Reactive protein and metabolic disorders in the indigenous population of the Republic of Sakha (Yakutia)
BACKGROUND: C-reactive protein is widely used in population-based studies as a marker of systemic inflammation associated with metabolic disorders. However, the characteristics of these associations in indigenous populations of northern regions remain insufficiently studied. AIM: This work aimed to evaluate the association between C-reactive protein levels and metabolic disorders in the indigenous population of the Republic of Sakha (Yakutia), ta…
Intestinal microbiota of indigenous peoples of the North
BACKGROUND: The microbiota of the indigenous population of the North may play a pivotal role in the development of the polar (northern) type of metabolism supporting increased energy demands and maintaining body homeostasis in extreme cold climates. However, this area remains relatively understudied. Sequencing of bacterial 16S rRNA allows for establishing the full taxonomic composition of microbial communities, thereby facilitating novel insight…
Brown adipose tissue thermogenesis among young adults in northeastern Siberia and Midwest United States and its relationship with other biological adaptations to cold climates
OBJECTIVES: Recent research suggests that brown adipose tissue (BAT) plays a functional role in non-shivering thermogenesis; however, few studies have examined population variation in BAT or its relationship with other mechanisms of adaptation to cold stress. This study characterized BAT thermogenesis and other adaptive responses to low temperatures among Indigenous Siberian young adults and young adults living near Chicago, IL. MATERIALS AND MET…
Lipid Metabolism and Metabolic Disorders in the Yakut Population
Extreme climatic conditions of the North with low temperatures and the traditional diet are responsible for development of a specific mechanisms of lipid metabolism among the indigenous peoples of the Sakha (Yakutia) Republic. The evolutionary patterns of lipid metabolism fixed in the genome in the form of polymorphic genetic markers are important for the development of regional healthcare programs for prevention of metabolic syndrome and cardiov…
Evidence for a sensitive period of plasticity in brown adipose tissue during early childhood among indigenous Siberians
OBJECTIVES: Evolutionary theorists have debated the adaptive significance of developmental plasticity in organisms with long lifespans such as humans. This debate in part stems from uncertainty regarding the timing of sensitive periods. Does sensitivity to environmental signals fluctuate across development or does it steadily decline? We investigated developmental plasticity in brown adipose tissue (BAT) among indigenous Siberians in order to exp…
Brown adipose tissue, energy expenditure, and biomarkers of cardio‐metabolic health among the Yakut (Sakha) of northeastern Siberia
OBJECTIVES: This study provides the first investigation of non-shivering thermogenesis (NST) and brown adipose tissue (BAT) activity among an indigenous circumpolar population, the Yakut of northeastern Siberia. The study also examines the health significance of BAT activity in this population by testing the relationships between BAT thermogenesis and biomarkers of cardio-metabolic disease risk, such as percent body fat and blood glucose and chol…
Evidence for a sensitive period of plasticity in brown adipose tissue during early childhood among indigenous Siberians
OBJECTIVES: Evolutionary theorists have debated the adaptive significance of developmental plasticity in organisms with long lifespans such as humans. This debate in part stems from uncertainty regarding the timing of sensitive periods. Does sensitivity to environmental signals fluctuate across development or does it steadily decline? We investigated developmental plasticity in brown adipose tissue (BAT) among indigenous Siberians in order to exp…
Brown adipose tissue, energy expenditure, and biomarkers of cardio‐metabolic health among the Yakut (Sakha) of northeastern Siberia
OBJECTIVES: This study provides the first investigation of non-shivering thermogenesis (NST) and brown adipose tissue (BAT) activity among an indigenous circumpolar population, the Yakut of northeastern Siberia. The study also examines the health significance of BAT activity in this population by testing the relationships between BAT thermogenesis and biomarkers of cardio-metabolic disease risk, such as percent body fat and blood glucose and chol…
Lipid Metabolism and Metabolic Disorders in the Yakut Population
Extreme climatic conditions of the North with low temperatures and the traditional diet are responsible for development of a specific mechanisms of lipid metabolism among the indigenous peoples of the Sakha (Yakutia) Republic. The evolutionary patterns of lipid metabolism fixed in the genome in the form of polymorphic genetic markers are important for the development of regional healthcare programs for prevention of metabolic syndrome and cardiov…
Evidence for a sensitive period of plasticity in brown adipose tissue during early childhood among indigenous Siberians
OBJECTIVES: Evolutionary theorists have debated the adaptive significance of developmental plasticity in organisms with long lifespans such as humans. This debate in part stems from uncertainty regarding the timing of sensitive periods. Does sensitivity to environmental signals fluctuate across development or does it steadily decline? We investigated developmental plasticity in brown adipose tissue (BAT) among indigenous Siberians in order to exp…
Brown adipose tissue thermogenesis among young adults in northeastern Siberia and Midwest United States and its relationship with other biological adaptations to cold climates
OBJECTIVES: Recent research suggests that brown adipose tissue (BAT) plays a functional role in non-shivering thermogenesis; however, few studies have examined population variation in BAT or its relationship with other mechanisms of adaptation to cold stress. This study characterized BAT thermogenesis and other adaptive responses to low temperatures among Indigenous Siberian young adults and young adults living near Chicago, IL. MATERIALS AND MET…
Intestinal microbiota of indigenous peoples of the North
BACKGROUND: The microbiota of the indigenous population of the North may play a pivotal role in the development of the polar (northern) type of metabolism supporting increased energy demands and maintaining body homeostasis in extreme cold climates. However, this area remains relatively understudied. Sequencing of bacterial 16S rRNA allows for establishing the full taxonomic composition of microbial communities, thereby facilitating novel insight…
C-Reactive protein and metabolic disorders in the indigenous population of the Republic of Sakha (Yakutia)
BACKGROUND: C-reactive protein is widely used in population-based studies as a marker of systemic inflammation associated with metabolic disorders. However, the characteristics of these associations in indigenous populations of northern regions remain insufficiently studied. AIM: This work aimed to evaluate the association between C-reactive protein levels and metabolic disorders in the indigenous population of the Republic of Sakha (Yakutia), ta…
Biology (4 works) · Endocrinology (4 works) · Physiology (4 works) · Adipose tissue (3 works) · Adipose Tissue and Metabolism (3 works) · Brown adipose tissue (3 works) · Medicine (3 works) · Population (3 works) · Thermogenesis (3 works) · Adipokines, Inflammation, and Metabolic Diseases (2 works)