Keiichi Omoto
Biographic Data
| ID | 220182 |
|---|---|
| NAME | Keiichi Omoto |
| GIVEN NAMES | Keiichi |
| FAMILY NAME | Omoto |
| SIGNATURE | OMOTO K |
| AFFILIATIONS | The University of Tokyo |
| VERIFIED | No |
| TOTAL WORKS | 33 |
| TOTAL CITATIONS | 10 |
| AUTHOR COUNT | 33 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1962 |
| LATEST PUBLICATION YEAR | 2020 |
| H-INDEX | 2 |
An integrated study of the human skeletal remains discovered in Escalon Cave, northeastern Mindanao, the Philippines
We examined fragmentary human skeletal remains from Escalon Cave near Surigao City, northeastern Mindanao, the Philippines, with respect to the morphology of bones and teeth, radiocarbon dating, and mitochondrial DNA (mtDNA) haplogroup. These remains contained parts of the left temporal bone, the right humerus, the right femur, the upper right first and second premolars, and the first molar. They are presumed to belong to an early-middle adult ma…
Tsuboi Shōgorō (1863–1913)
Tsuboi Shōgorō was the founder of anthropology in Japan. He was well grounded in natural history and established the Anthropological Society of Japan in 1884. He taught anthropology at the Science University and published papers and books on diverse topics ranging across both physical and cultural aspects of humans. After his death at the age of 50, the diversity of topics that featured in anthropological journals was gone. A group of young anthr…
Dual origins of the Japanese: Common ground for hunter-gatherer and farmer Y chromosomes
Β-Globin Gene Cluster Haplotype Frequencies in Khalkhs and Buryats of Mongolia
Beta-globin gene cluster haplotype frequencies of 169 Khalkhs and 145 Buryats were estimated, and their characteristics were compared with those of Evenkis, Oroqens, Koreans, Japanese, and three Colombian Amerindian groups. The present study suggests that Colombian Amerindians diverged first from Asian populations and then Buryats diverged from other Asian populations
Characteristic [Beta]-Globin Gene Cluster Haplotypes of Evenkis and Oroqens in North China
Haplotype frequencies of the beta-globin gene cluster were estimated for 114 Evenkis and 81 Oroqens from northeast China, and their characteristics were compared with those in Japanese, Koreans, and three Colombian Amerindian groups of South America (Wayuu, Kamsa, and Inga tribes). A major 5' subhaplotype (5' to the delta-globin gene) was + - - - - in Evenkis, whereas + - - - -, - + + - +, and - + - + + were the major subhaplotypes in Oroqens. On…
Population Genetic Studies on Nine Aboriginal Ethnic Groups of Taiwan. I. Red Cell Enzyme Systems
Population genetic study of nine aboriginal ethnic groups of Taiwan(Ami, Atayal, Bunun, Paiwan, Puyuma, Rukai, Saisiat, Tsou, and Yami) wascarried out. Twelve red cell enzymes (AcP, AK, CA1, CA2, EsD, GLO, GPT, GOT, LDH, MDH, PGD, and PGM1) were analyzed by isoelectric focusingmethod and starch gel electrophoretic method. Six loci (AcP, EsD, GLO, GPT, PGD, and PGM1) were polymorphic. Three alleles (PGM1*6, GPT*6, andEsD*7) were in relatively high…
Genetic origins of the Japanese: A partial support for the dual structure hypothesis
Based on the morphological characteristics of the skull and teeth, Hanihara ([1991] Japan Review 2:1–33) proposed the “dual structure model” for the formation of modern Japanese populations. We examine this model by dividing it into two independent hypotheses: 1) the Upper Paleolithic population of Japan that gave rise to the Neolithic Jomon people was of southeast Asian origin, and 2) modern Ainu and Ryukyuan (Okinawa) populations are direct des…
Genetic origins of the Japanese: A partial support for the dual structure hypothesis
Based on the morphological characteristics of the skull and teeth, Hanihara ([1991] Japan Review 2:1-33) proposed the "dual structure model" for the formation of modern Japanese populations. We examine this model by dividing it into two independent hypotheses: 1) the Upper Paleolithic population of Japan that gave rise to the Neolithic Jomon people was of southeast Asian origin, and 2) modern Ainu and Ryukyuan (Okinawa) populations are direct des…
Y chromosome markers and trans-Bering Strait dispersals
Five polymorphisms involving two paternally inherited loci were surveyed in 38 world populations (n = 1,631) to investigate the origins of Native Americans. One of the six Y chromosome combination haplotypes (1T) was found at relatively high frequencies (17.8-75.0%) in nine Native American populations (n = 206) representing the three major linguistic divisions in the New World. Overall, these data do not support the Greenberg et al. (1986) tripar…
HLA class II alleles in Ainu living in Hidaka district, Hokkaido, northern Japan
The Ainu people are considered to be the descendants of preagricultural native populations of northern Japan, while the majority of the population of contemporary Japan (Wajin) is descended mainly from postneolithic migrants. Polymorphisms of the HLA-DRB1, DRB3, and DQB1 alleles were investigated in DNA samples of 50 Ainu living in Hidaka district, Hokkaido. Unique features of the Ainu in this study were high incidences of DRB1*1401, DRB1*1406, a…
Genetic Polymorphism of ADA in Taiwan Aboriginal Populations: New ADA Variants Detected by Isoelectric Focusing Method
ADA subtype polymorphism in nine aboriginal populations (Gaoshan) of Taiwan was studied by means of the IEF method. A new ADA variant allele, ADA*Taiwan1, was in a high allele frequency in two Gaoshan populations, the Amis and the Paiwans. Another new variant, ADA*Taiwan2, was found in only one case of heterozygote in the Saisiats. Allele frequencies of a common allele, ADA*2, in the Paiwans and the Amis were the highest among the Asian populatio…
Population Genetic Study in Hainan Island, China. II. Genetic Affinity Analyses
A population genetic study was carried out on six populations (two Li populations, two Miao populations, one Hui population, and one Han population) in Hainan Island, Southern China. Allele frequency data for these six populations and those for some other Asian populations were used to estimate genetic distances between populations, and genetic affinity dendrograms and networks were constructed by using UPGMA and the neighbor-joining method, resp…
Population Genetic Study in Hainan Island, China. I. Distribution of Blood Genetic Markers: I. Distribution of Blood Genetic Markers
Results obtained in a joint Japanese-Chinese field study in Hainan Island are presented. Three national minority groups, Li, Miao and Hui, together with Han as control were studied. A total of 23 blood genetic markers comprising 9 blood groups, 7 red cell enzymes and 7 serum proteins, and also alpha and beta thalassemias were examined, and phenotype and allele frequencies are tabulated. The distributions of allele frequencies differ markedly amon…
DNA typing for HLA-DR using polymerase chain reaction: Application to frozen blood
HLA-DR specificities were typed using crude DNA from frozen blood samples. Crude extracts of DNA were prepared by boiling blood samples, and a specific segment of the HLA-DRB gene was amplified in vitro by polymerase chain reaction. After blotting to nylon filters, each specificity was detected by nonradioactively (dig-1l-dUTP)-labeled oligonucleotide probes. The results agreed with serological typing. Moreover, some DR subspecificities defined b…
Differentiation of mitochondrial DNA types inMacaca fascicularis
On the effect of the fluctuating population size on the age of a mutant gene
The age of a mutant gene was studied under various cases of population size fluctuation. A Monte Carlo method was used to simulate a branching process under the assumption that the probability distribution of descendant gene numbers follows a Poisson distribution. It is shown that a population with a constant population size tend to have larger age of a mutant gene than populations in which the size is fluctuating. It was also shown that for a Ne…
Polymorphism in the mitochondrial DNA of cynomolgus monkeys
The distribution of red cell enzyme and serum protein types in a sample from Iwate, northern Japan, with the description of geographical cline of Gc subtypes
Blood samples from 500 healthy blood donors of Iwate Prefecture, northern Japan, were examined for polymorphism of the following red cell enzyme and serum protein systems by starch-gel electrophoresis and in part by isoelectrofocusing: ACP, PGMI, ESD, GPT, Hp, Tf and subtypes of PGMI and Gc. The distribution f phenotypes and allele frequencies estimated for each system was essentially similar to those reported in other areas of Japan. However, wh…
Polymorphism of γ-aminobutyric Acid Transaminase (Gabat) in Japanese
Polymorphism of γ-aminobutyric acid transaminase (GABAT) was investigated in a total of 75 liver samples from unrelated Japanese using a orizontal starch gel electrophoresis. Three common phenotypes were observed, which corresponded to GABAT 1, GABAT 2-1, and GABAT 2, controlled by two alleles, GABAT1 andGABAT2. The estimated allele frequencies of GABAT1 and GABAT2 were 0.547 and 0.453, respectivly. This result was not significantly differerent o…
Glutamic-pyruvic transaminase (GPT) in non-human primates II. Implication of the interspecific variation in enzyme activity
Studies on the Electrophoretic Variation of Soluble GlutamicOxaloacetic Transaminase (s-GOT) in Non-Human Primates
The electrophoretic variation of soluble glutamic-oxaloacetic transaminase (s-GOT) in red cells of 26 species of non-human primates including one hybrid species and those in liver homogenates of 9 Macaca species were investigated. It was demonstrated that red cell GOT is present widely in the non-human primates so far examined and the strength of the zymograms were nearly equal. The intraspecific variation of s-GOT was confirmed in Macaca cyclopi…
The Genetic Origins of the Philippine Negritos
Glutamic-pyruvic transaminase (GPT) in non-human primates, I. Its activities and electrophoretic variation in red blood cells
An Analysis of the ABO Gene Frequency Cline in Japan: A Migration Model
The well known cline in ABO blood group gene frequencies in Japan was analysed based on the working hypothesis of a transient cline formed by the admixture of two heterogeneous populations by diffusion.Mathematically, the model corresponds to solving the diffusion equation with a step function as the initial condition. Using the A allele frequency data, the position of the initial discontinuity in the gene frequency is estimated by simulation as …
The Distribution of Genetic Markers in Blood Samples from Okinawa, the Ryukyus: II. The Distribution of Several Red Cell Enzyme Types in Ishigaki Island
A total of more than 780 red cell samples obtained in Ishigaki City as part of the "Joint Survey on Okinawa by Nine Japanese Societies" were examined as to polymorphic types of four enzymes: AcP, PGM, 6-PGD, ADA by starch-gel electrophoresis. Screening of G-6PD variants was also carried out.In AcP system (N=807), the frequencies of pα and Pι were 0.2702 and 0.7298, respectively. Two samples were found to have unusual phenotypes. In PGM1 system (N…
The Genetic Origins of the Philippine Negritos
Β-Globin Gene Cluster Haplotype Frequencies in Khalkhs and Buryats of Mongolia
Beta-globin gene cluster haplotype frequencies of 169 Khalkhs and 145 Buryats were estimated, and their characteristics were compared with those of Evenkis, Oroqens, Koreans, Japanese, and three Colombian Amerindian groups. The present study suggests that Colombian Amerindians diverged first from Asian populations and then Buryats diverged from other Asian populations
Population Genetic Studies on Nine Aboriginal Ethnic Groups of Taiwan. I. Red Cell Enzyme Systems
Population genetic study of nine aboriginal ethnic groups of Taiwan(Ami, Atayal, Bunun, Paiwan, Puyuma, Rukai, Saisiat, Tsou, and Yami) wascarried out. Twelve red cell enzymes (AcP, AK, CA1, CA2, EsD, GLO, GPT, GOT, LDH, MDH, PGD, and PGM1) were analyzed by isoelectric focusingmethod and starch gel electrophoretic method. Six loci (AcP, EsD, GLO, GPT, PGD, and PGM1) were polymorphic. Three alleles (PGM1*6, GPT*6, andEsD*7) were in relatively high…
Characteristic [Beta]-Globin Gene Cluster Haplotypes of Evenkis and Oroqens in North China
Haplotype frequencies of the beta-globin gene cluster were estimated for 114 Evenkis and 81 Oroqens from northeast China, and their characteristics were compared with those in Japanese, Koreans, and three Colombian Amerindian groups of South America (Wayuu, Kamsa, and Inga tribes). A major 5' subhaplotype (5' to the delta-globin gene) was + - - - - in Evenkis, whereas + - - - -, - + + - +, and - + - + + were the major subhaplotypes in Oroqens. On…
Mikkabi Man and the Fossil-bearing Deposits from Tadaki Limestone Quarry at Mikkabi, Central Japan: 2. The Limestone-fissure Site of Mikkabi
[in Japanese]
Measurements of Skin Reflectance in a Japanese Twin Sample
The luminous reflectance of the skin has been measured in a sample of 87 monozygotic, 14 dizygotic (like-sexed) and 11 unlike-sexed twin pairs aged from 12 to 18 years, using the Phtovolt photoelectric reflection meter (Mod. 610). Measurements were taken with the green tristimulus filter designed to represent lightness of colours, on the outer and inner surfaces of the upper arm, to which those on the forehead, chest, shoulder and back of the han…
Studies of Skin Colour among Hybrid Subjects in Japan with Special Reference to Measurements of Sun-tanning
An attempt was made to measure the degree of natural sun-tanning among the hybrid subjects of the Elizabeth Sanders Home, Japan. The skin reflectance was measured on 69 males and 37 females, 7 to 14 years of age, in March and in September of the same year using the Photovolt photoelectric reflection meter.Although the absolute decrease in the skin reflectance during summer tended to correlate positively with the initial degree of lightness of the…
Distribution of the electrophoretic variants of serum alpha1-antitrypsin in six species of the macaques
Electrophoretic Variation of Human Serum α 1 -antitrypsin in Japan
Individual variation of serum α1-antitrypsin, a protease inhibiting protein, was studied by starch gel electrophoresis. A total of 1, 475 serum and plasma samples taken from three racial groups, namely Japanese, Ainu and U. S. A. White, were examined. Seven phenotypes altogether found were classified according to FAGERHOL's nomenclature of Pi-system. In each population group the type MM was by far the most common, while other variants had low inc…
Distribution of Phenotypes and Gene Frequencies of Six Red Cell Enzymes in the District of Tohoku, Northern Part of Japan
Genetic polymorphism of six red cell enzymes, namely, acid phosphatase (AcP), 6-phosphogluconate dehydrogenase (6-PGD), phosphoglucomutase (PGM), adenosine deaminase (ADA), phosphohexose isomerase (PHI) and adenylate kinase (AK) have been studied by the method of starch gel electrophoresis. The red cell samples were taken from unrelated individuals in three prefectures in the district of Tohoku, nothern part of Japan. In the present samples heter…
The Distribution of Genetic Markers in Blood Samples from Okinawa, the Ryukyus: The Distribution of Red Cell GPT and GOT Types in Ishigaki Island
As a part of investigating genetic markers in bloods from Ryukyuans, red cell GPT (glutamic-pyruvic transaminase) and GOT (glutamic-oxaloacetic transaminase) polymorphisms were examined in 765 samples collected in Ishi-gaki Island.In GPT system, the gene frequencies observed were Gpt1=0.535 and Gpt2=0.465, and in GOT system, only two phenotypes, GOT 1 and 2-1, were identified.Compared with other populations of this country, most notable features …
The Distribution of Genetic Markers in Blood Samples from Okinawa, the Ryukyus: The Distribution of Red Cell Antigen Groups in Ishigaki Island.19740827
A total of 869 blood samples collected in Ishigaki Island were tested for 9 blood groups-ABO, MNSs, Rh, Q, Lewis, Duffy, Kell, Kidd and Diego blood groups, and the following results were obtained.The O gene frequency (γ) of the ABO blood groups was considerably higher than that of the Japanese, and the distribution of MNSs groups appeared to be different from it.The incidence of Rh negative individuals was 1.04%, which was intermediate between th…
The Distribution of Genetic Markers in Blood Samples from Okinawa, the Ryukyus: II. The Distribution of Several Red Cell Enzyme Types in Ishigaki Island
A total of more than 780 red cell samples obtained in Ishigaki City as part of the "Joint Survey on Okinawa by Nine Japanese Societies" were examined as to polymorphic types of four enzymes: AcP, PGM, 6-PGD, ADA by starch-gel electrophoresis. Screening of G-6PD variants was also carried out.In AcP system (N=807), the frequencies of pα and Pι were 0.2702 and 0.7298, respectively. Two samples were found to have unusual phenotypes. In PGM1 system (N…
Glutamic-pyruvic transaminase (GPT) in non-human primates, I. Its activities and electrophoretic variation in red blood cells
An Analysis of the ABO Gene Frequency Cline in Japan: A Migration Model
The well known cline in ABO blood group gene frequencies in Japan was analysed based on the working hypothesis of a transient cline formed by the admixture of two heterogeneous populations by diffusion.Mathematically, the model corresponds to solving the diffusion equation with a step function as the initial condition. Using the A allele frequency data, the position of the initial discontinuity in the gene frequency is estimated by simulation as …
Studies on the Electrophoretic Variation of Soluble GlutamicOxaloacetic Transaminase (s-GOT) in Non-Human Primates
The electrophoretic variation of soluble glutamic-oxaloacetic transaminase (s-GOT) in red cells of 26 species of non-human primates including one hybrid species and those in liver homogenates of 9 Macaca species were investigated. It was demonstrated that red cell GOT is present widely in the non-human primates so far examined and the strength of the zymograms were nearly equal. The intraspecific variation of s-GOT was confirmed in Macaca cyclopi…
The Genetic Origins of the Philippine Negritos
Glutamic-pyruvic transaminase (GPT) in non-human primates II. Implication of the interspecific variation in enzyme activity
Polymorphism of γ-aminobutyric Acid Transaminase (Gabat) in Japanese
Polymorphism of γ-aminobutyric acid transaminase (GABAT) was investigated in a total of 75 liver samples from unrelated Japanese using a orizontal starch gel electrophoresis. Three common phenotypes were observed, which corresponded to GABAT 1, GABAT 2-1, and GABAT 2, controlled by two alleles, GABAT1 andGABAT2. The estimated allele frequencies of GABAT1 and GABAT2 were 0.547 and 0.453, respectivly. This result was not significantly differerent o…
Polymorphism in the mitochondrial DNA of cynomolgus monkeys
The distribution of red cell enzyme and serum protein types in a sample from Iwate, northern Japan, with the description of geographical cline of Gc subtypes
Blood samples from 500 healthy blood donors of Iwate Prefecture, northern Japan, were examined for polymorphism of the following red cell enzyme and serum protein systems by starch-gel electrophoresis and in part by isoelectrofocusing: ACP, PGMI, ESD, GPT, Hp, Tf and subtypes of PGMI and Gc. The distribution f phenotypes and allele frequencies estimated for each system was essentially similar to those reported in other areas of Japan. However, wh…
Differentiation of mitochondrial DNA types inMacaca fascicularis
On the effect of the fluctuating population size on the age of a mutant gene
The age of a mutant gene was studied under various cases of population size fluctuation. A Monte Carlo method was used to simulate a branching process under the assumption that the probability distribution of descendant gene numbers follows a Poisson distribution. It is shown that a population with a constant population size tend to have larger age of a mutant gene than populations in which the size is fluctuating. It was also shown that for a Ne…
DNA typing for HLA-DR using polymerase chain reaction: Application to frozen blood
HLA-DR specificities were typed using crude DNA from frozen blood samples. Crude extracts of DNA were prepared by boiling blood samples, and a specific segment of the HLA-DRB gene was amplified in vitro by polymerase chain reaction. After blotting to nylon filters, each specificity was detected by nonradioactively (dig-1l-dUTP)-labeled oligonucleotide probes. The results agreed with serological typing. Moreover, some DR subspecificities defined b…
Population Genetic Study in Hainan Island, China. I. Distribution of Blood Genetic Markers: I. Distribution of Blood Genetic Markers
Results obtained in a joint Japanese-Chinese field study in Hainan Island are presented. Three national minority groups, Li, Miao and Hui, together with Han as control were studied. A total of 23 blood genetic markers comprising 9 blood groups, 7 red cell enzymes and 7 serum proteins, and also alpha and beta thalassemias were examined, and phenotype and allele frequencies are tabulated. The distributions of allele frequencies differ markedly amon…
Population Genetic Study in Hainan Island, China. II. Genetic Affinity Analyses
A population genetic study was carried out on six populations (two Li populations, two Miao populations, one Hui population, and one Han population) in Hainan Island, Southern China. Allele frequency data for these six populations and those for some other Asian populations were used to estimate genetic distances between populations, and genetic affinity dendrograms and networks were constructed by using UPGMA and the neighbor-joining method, resp…
Genetic Polymorphism of ADA in Taiwan Aboriginal Populations: New ADA Variants Detected by Isoelectric Focusing Method
ADA subtype polymorphism in nine aboriginal populations (Gaoshan) of Taiwan was studied by means of the IEF method. A new ADA variant allele, ADA*Taiwan1, was in a high allele frequency in two Gaoshan populations, the Amis and the Paiwans. Another new variant, ADA*Taiwan2, was found in only one case of heterozygote in the Saisiats. Allele frequencies of a common allele, ADA*2, in the Paiwans and the Amis were the highest among the Asian populatio…
HLA class II alleles in Ainu living in Hidaka district, Hokkaido, northern Japan
The Ainu people are considered to be the descendants of preagricultural native populations of northern Japan, while the majority of the population of contemporary Japan (Wajin) is descended mainly from postneolithic migrants. Polymorphisms of the HLA-DRB1, DRB3, and DQB1 alleles were investigated in DNA samples of 50 Ainu living in Hidaka district, Hokkaido. Unique features of the Ainu in this study were high incidences of DRB1*1401, DRB1*1406, a…
Genetic origins of the Japanese: A partial support for the dual structure hypothesis
Based on the morphological characteristics of the skull and teeth, Hanihara ([1991] Japan Review 2:1–33) proposed the “dual structure model” for the formation of modern Japanese populations. We examine this model by dividing it into two independent hypotheses: 1) the Upper Paleolithic population of Japan that gave rise to the Neolithic Jomon people was of southeast Asian origin, and 2) modern Ainu and Ryukyuan (Okinawa) populations are direct des…
Biology (29 works) · Gene (20 works) · Genetics (19 works) · Genetics (17 works) · Demography (16 works) · Population (16 works) · Allele (13 works) · Geography (13 works) · Evolutionary biology (11 works) · Forensic and Genetic Research (11 works)