Mirjam Kretzschmar
Biographic Data
| ID | 231781 |
|---|---|
| NAME | Mirjam Kretzschmar |
| GIVEN NAMES | Mirjam |
| FAMILY NAME | Kretzschmar |
| SIGNATURE | KRETZSCHMAR M |
| AFFILIATIONS | University Medical Center Utrecht |
| ORCID | 0000-0002-4394-7697 |
| VERIFIED | Yes |
| TOTAL WORKS | 20 |
| TOTAL CITATIONS | 4 |
| WORKS AS AUTHOR | 20 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1995 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 2 |
General population preferences for health-related protective behaviors during infectious disease emergencies
Citizen involvement in Covid-19 contact tracing with digital tools
Most interviewees hold a positive attitude towards self-led CT and using digital tools for this purpose. However, their intention for self-led CT may depend on various factors, such as prior experiences with regular CT, and their perceived self-efficacy to participate. Perspectives and needs of citizens should be considered for the future implementation of self-led CT in practice
Health behavior homophily can mitigate the spread of infectious diseases in small-world networks
Research has repeatedly shown that the spread of infectious diseases is influenced by properties of our social networks. Small-world like structures with densely connected clusters bridged by only a few connections, for example, are not only known to diminish disease spread, but also to increase the chance for a disease to spread to any part of the network. Clusters composed of individuals who show similar reactions to avoid infections (health be…
Impact of delays on effectiveness of contact tracing strategies for Covid-19
Background In countries with declining numbers of confirmed cases of COVID-19, lockdown measures are gradually being lifted. However, even if most physical distancing measures are continued, other public health measures will be needed to control the epidemic. Contact tracing via conventional methods or mobile app technology is central to control strategies during de-escalation of physical distancing. We aimed to identify key factors for a contact…
Clustering of chronic hepatitis B screening intentions in social networks of Moroccan immigrants in the Netherlands
The findings of our pilot study show clustering of screening intention among individuals in the same network. This provides opportunities for social network interventions to encourage participation in hepatitis B screening initiatives
The Rhythm of Risk
HIV risk perception plays a crucial role in the uptake of preventive strategies. We investigated how risk perception and its determinants changed between 1999 and 2018 in an open, prospective cohort of 1323 HIV-negative men who have sex with men (MSM). Risk perception, defined as the perceived likelihood of acquiring HIV in the past 6 months, changed over time: being relatively lower in 2008-2011, higher in 2012-2016, and again lower in 2017-2018…
Disability weights for the Global Burden of Disease 2013 study
BACKGROUND: The Global Burden of Disease (GBD) study assesses health losses from diseases, injuries, and risk factors using disability-adjusted life-years, which need a set of disability weights to quantify health levels associated with non-fatal outcomes. The objective of this study was to estimate disability weights for the GBD 2013 study. METHODS: We analysed data from new web-based surveys of participants aged 18-65 years, completed in four E…
Enhancing Syndromic Surveillance With Online Respondent-Driven Detection
Objectives. We investigated the feasibility of combining an online chain recruitment method (respondent-driven detection) and participatory surveillance panels to collect previously undetected information on infectious diseases via social networks of participants. Methods. In 2014, volunteers from 2 large panels in the Netherlands were invited to complete a survey focusing on symptoms of upper respiratory tract infections and to invite 4 individu…
Measuring underreporting and under-ascertainment in infectious disease datasets
When routine data are used to make decisions on resource allocation or to estimate epidemiological parameters in populations, it becomes important to understand when, where and to what extent these data represent the true picture of disease, and in some instances (such as priority setting) it is necessary to adjust for underestimation. MFs can be used to adjust notification and surveillance data to provide more realistic estimates of incidence
Perceived HIV Status is a Key Determinant of Unprotected Anal Intercourse Within Partnerships of Men Who Have Sex With Men in Amsterdam
The impact of demographic change on the estimated future burden of infectious diseases
There are clear, but diverging effects of an ageing population on the estimated disease burden of influenza and HBV in the Netherlands. Replacing static assumptions with a dynamic demographic approach appears essential for deriving realistic burden estimates for informing health policy
Development of a resource modelling tool to support decision makers in pandemic influenza preparedness
The AsiaFluCap Simulator is freely available software (http://www.cdprg.org) which can be used by policy makers, policy advisors, donors and other stakeholders involved in preparedness for providing evidence based and illustrative information on health care resource capacities during future pandemics. The tool can inform both preparedness plans and simulation exercises and can help increase the general understanding of dynamics in resource capaci…
Is Concurrency Driving HIV Transmission in Sub-Saharan African Sexual Networks? The Significance of Sexual Partnership Typology
Analysis of timeliness of infectious disease reporting in the Netherlands
Over the study period, many cases of the six notifiable diseases were not reported within two incubation periods, and many were reported more than three days after laboratory diagnosis. An increase in direct laboratory reporting of diagnoses to MHS would improve timeliness, as would the use of fax rather than post or e-mail. Automated reporting systems have to be explored in the Netherlands. Development of standardised and improved measures for t…
P2-181 Reconstructing the historical incidence of hepatitis C infection among Scotland's Idus
Introduction The historical incidence of hepatitis C virus (HCV) infection in Scotland's injecting drug user (IDU) population is unknown. From a public health perspective, accurate data on incidence rates over time would improve our understanding of the effects of harm reduction measures initiated in the late 1980s (needle/syringe exchanges, methadone treatment) on the transmission of HCV among Scotland's IDUs. Because HCV-antibody testing only c…
Collecting social contact data in the context of disease transmission
Can HIV epidemics among IDUs ‘trigger’ a generalised epidemic
Concurrent partnerships and the spread of HIV
OBJECTIVE: To examine how concurrent partnerships amplify the rate of HIV spread, using methods that can be supported by feasible data collection. METHODS: A fully stochastic simulation is used to represent a population of individuals, the sexual partnerships that they form and dissolve over time, and the spread of an infectious disease. Sequential monogamy is compared with various levels of concurrency, holding all other features of the infectio…
Concurrent partnerships and transmission dynamics in networks
Network structure plays a critical role in channeling person-to-person transmission of infectious disease agents like HIV. Stochastic simulations are used here to examine the effect of two structural attributes: concurrent partnerships (degree) and mixing patterns (degree-based homophily bias). Four alternative partnership scenarios are compared: (1) sequential monogamy, and concurrent partnerships with (2) random (3) assortative and (4) disassor…
A network modelling approach for assessing the efficiency of prevention strategies
Survey data and a simulation model based on a stochastic pair formation process are used to construct networks of sexual contacts. We model heterosexual partnerships which can be steady or casual depending on their average duration. Transmission of an infectious disease can take place in pairs of a susceptible and an infected individual. We study networks of sexual contacts accumulated during 1 year for different types of mixing patterns. The net…
Health behavior homophily can mitigate the spread of infectious diseases in small-world networks
Research has repeatedly shown that the spread of infectious diseases is influenced by properties of our social networks. Small-world like structures with densely connected clusters bridged by only a few connections, for example, are not only known to diminish disease spread, but also to increase the chance for a disease to spread to any part of the network. Clusters composed of individuals who show similar reactions to avoid infections (health be…
A network modelling approach for assessing the efficiency of prevention strategies
Survey data and a simulation model based on a stochastic pair formation process are used to construct networks of sexual contacts. We model heterosexual partnerships which can be steady or casual depending on their average duration. Transmission of an infectious disease can take place in pairs of a susceptible and an infected individual. We study networks of sexual contacts accumulated during 1 year for different types of mixing patterns. The net…
Concurrent partnerships and transmission dynamics in networks
Network structure plays a critical role in channeling person-to-person transmission of infectious disease agents like HIV. Stochastic simulations are used here to examine the effect of two structural attributes: concurrent partnerships (degree) and mixing patterns (degree-based homophily bias). Four alternative partnership scenarios are compared: (1) sequential monogamy, and concurrent partnerships with (2) random (3) assortative and (4) disassor…
A network modelling approach for assessing the efficiency of prevention strategies
Survey data and a simulation model based on a stochastic pair formation process are used to construct networks of sexual contacts. We model heterosexual partnerships which can be steady or casual depending on their average duration. Transmission of an infectious disease can take place in pairs of a susceptible and an infected individual. We study networks of sexual contacts accumulated during 1 year for different types of mixing patterns. The net…
Concurrent partnerships and the spread of HIV
OBJECTIVE: To examine how concurrent partnerships amplify the rate of HIV spread, using methods that can be supported by feasible data collection. METHODS: A fully stochastic simulation is used to represent a population of individuals, the sexual partnerships that they form and dissolve over time, and the spread of an infectious disease. Sequential monogamy is compared with various levels of concurrency, holding all other features of the infectio…
Can HIV epidemics among IDUs ‘trigger’ a generalised epidemic
Collecting social contact data in the context of disease transmission
Analysis of timeliness of infectious disease reporting in the Netherlands
Over the study period, many cases of the six notifiable diseases were not reported within two incubation periods, and many were reported more than three days after laboratory diagnosis. An increase in direct laboratory reporting of diagnoses to MHS would improve timeliness, as would the use of fax rather than post or e-mail. Automated reporting systems have to be explored in the Netherlands. Development of standardised and improved measures for t…
P2-181 Reconstructing the historical incidence of hepatitis C infection among Scotland's Idus
Introduction The historical incidence of hepatitis C virus (HCV) infection in Scotland's injecting drug user (IDU) population is unknown. From a public health perspective, accurate data on incidence rates over time would improve our understanding of the effects of harm reduction measures initiated in the late 1980s (needle/syringe exchanges, methadone treatment) on the transmission of HCV among Scotland's IDUs. Because HCV-antibody testing only c…
The impact of demographic change on the estimated future burden of infectious diseases
There are clear, but diverging effects of an ageing population on the estimated disease burden of influenza and HBV in the Netherlands. Replacing static assumptions with a dynamic demographic approach appears essential for deriving realistic burden estimates for informing health policy
Development of a resource modelling tool to support decision makers in pandemic influenza preparedness
The AsiaFluCap Simulator is freely available software (http://www.cdprg.org) which can be used by policy makers, policy advisors, donors and other stakeholders involved in preparedness for providing evidence based and illustrative information on health care resource capacities during future pandemics. The tool can inform both preparedness plans and simulation exercises and can help increase the general understanding of dynamics in resource capaci…
Is Concurrency Driving HIV Transmission in Sub-Saharan African Sexual Networks? The Significance of Sexual Partnership Typology
Measuring underreporting and under-ascertainment in infectious disease datasets
When routine data are used to make decisions on resource allocation or to estimate epidemiological parameters in populations, it becomes important to understand when, where and to what extent these data represent the true picture of disease, and in some instances (such as priority setting) it is necessary to adjust for underestimation. MFs can be used to adjust notification and surveillance data to provide more realistic estimates of incidence
Perceived HIV Status is a Key Determinant of Unprotected Anal Intercourse Within Partnerships of Men Who Have Sex With Men in Amsterdam
Disability weights for the Global Burden of Disease 2013 study
BACKGROUND: The Global Burden of Disease (GBD) study assesses health losses from diseases, injuries, and risk factors using disability-adjusted life-years, which need a set of disability weights to quantify health levels associated with non-fatal outcomes. The objective of this study was to estimate disability weights for the GBD 2013 study. METHODS: We analysed data from new web-based surveys of participants aged 18-65 years, completed in four E…
Enhancing Syndromic Surveillance With Online Respondent-Driven Detection
Objectives. We investigated the feasibility of combining an online chain recruitment method (respondent-driven detection) and participatory surveillance panels to collect previously undetected information on infectious diseases via social networks of participants. Methods. In 2014, volunteers from 2 large panels in the Netherlands were invited to complete a survey focusing on symptoms of upper respiratory tract infections and to invite 4 individu…
Impact of delays on effectiveness of contact tracing strategies for Covid-19
Background In countries with declining numbers of confirmed cases of COVID-19, lockdown measures are gradually being lifted. However, even if most physical distancing measures are continued, other public health measures will be needed to control the epidemic. Contact tracing via conventional methods or mobile app technology is central to control strategies during de-escalation of physical distancing. We aimed to identify key factors for a contact…
Clustering of chronic hepatitis B screening intentions in social networks of Moroccan immigrants in the Netherlands
The findings of our pilot study show clustering of screening intention among individuals in the same network. This provides opportunities for social network interventions to encourage participation in hepatitis B screening initiatives
The Rhythm of Risk
HIV risk perception plays a crucial role in the uptake of preventive strategies. We investigated how risk perception and its determinants changed between 1999 and 2018 in an open, prospective cohort of 1323 HIV-negative men who have sex with men (MSM). Risk perception, defined as the perceived likelihood of acquiring HIV in the past 6 months, changed over time: being relatively lower in 2008-2011, higher in 2012-2016, and again lower in 2017-2018…
Health behavior homophily can mitigate the spread of infectious diseases in small-world networks
Research has repeatedly shown that the spread of infectious diseases is influenced by properties of our social networks. Small-world like structures with densely connected clusters bridged by only a few connections, for example, are not only known to diminish disease spread, but also to increase the chance for a disease to spread to any part of the network. Clusters composed of individuals who show similar reactions to avoid infections (health be…
Citizen involvement in Covid-19 contact tracing with digital tools
Most interviewees hold a positive attitude towards self-led CT and using digital tools for this purpose. However, their intention for self-led CT may depend on various factors, such as prior experiences with regular CT, and their perceived self-efficacy to participate. Perspectives and needs of citizens should be considered for the future implementation of self-led CT in practice
General population preferences for health-related protective behaviors during infectious disease emergencies
Medicine (18 works) · Public health (11 works) · Computer Science (9 works) · COVID-19 epidemiological studies (9 works) · Demography (8 works) · Environmental health (7 works) · HIV, Drug Use, Sexual Risk (6 works) · Internal Medicine (6 works) · Population (6 works) · Psychology (6 works)