Wilfred F Mbacham
Biographic Data
| ID | 2322887 |
|---|---|
| NAME | Wilfred F Mbacham |
| GIVEN NAMES | Wilfred F |
| FAMILY NAME | Mbacham |
| SIGNATURE | MBACHAM W F |
| AFFILIATIONS | Université de Yaoundé I |
| ORCID | 0000-0002-3934-3233 |
| VERIFIED | Yes |
| TOTAL WORKS | 11 |
| TOTAL CITATIONS | 11 |
| AUTHOR COUNT | 11 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2009 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 2 |
Oxidative stress in malaria and typhoid fever
Oxidative stress is a key factor in the pathogenesis of many infectious diseases, including typhoid fever and malaria. Co-infection with these diseases poses a particular challenge, as both are associated with increased production of reactive species that can damage tissues, trigger oxidative stress, and exacerbate disease. To cope with this oxidative insult, cells have a defense system consisting of antioxidant molecules that can terminate the o…
The R21 malaria vaccine
Malaria impacts millions of lives, mostly in continental Africa, and especially so in the WHO African Region, where 233 million cases accounted for about 94% of global cases in 2022 [1].Progress in curbing malaria has somewhat plateaued since 2015 [2, 3] due to factors that include drug and insecticide resistance, poor availability of rapid diagnostic tests (RDTs) and artemisinin-based combination therapies (ACTs), and socio-behavior factors [3].…
Effectiveness of malaria chemoprevention in the first two years of life in Cameroon and Côte d’Ivoire compared to standard of care
Cameroon - NCT05889052; Côte d'Ivoire - NCT05856357
Assessing Asymptomatic Malaria Carriage of Plasmodium falciparum and Non-falciparum Species in Children Resident in Nkolbisson, Yaoundé, Cameroon
Malaria is still a threat to public health as it remains the first endemic disease in the world. It is a pervasive parasitic disease in tropical and subtropical regions where asymptomatic malaria infection among humans serves as a significant reservoir for transmission. A rapid and correct diagnosis is considered to be an important strategy in the control of the disease especially in children, who are the most vulnerable group. This study assesse…
Mind the gap
BACKGROUND: Artemisinin combination therapy (ACT) has been the first-line treatment for uncomplicated malaria in Cameroon since 2004 and Nigeria since 2005, though many febrile patients receive less effective antimalarials. Patients often rely on providers to select treatment, and interventions are needed to improve providers' practice and encourage them to adhere to clinical guidelines. METHODS: Providers' adherence to malaria treatment guidelin…
What determines providers' stated preference for the treatment of uncomplicated malaria
As agents for their patients, providers often make treatment decisions on behalf of patients, and their choices can affect health outcomes. However, providers operate within a network of relationships and are agents not only for their patients, but also other health sector actors, such as their employer, the Ministry of Health, and pharmaceutical suppliers. Providers' stated preferences for the treatment of uncomplicated malaria were examined to …
Medicine sellers’ perspectives on their role in providing health care in North-West Cameroon
BACKGROUND: Increasing recognition of the importance of medicine sellers in low-resource settings has emerged alongside assumptions that their motives and capacities primarily relate to profit maximization. This article suggests a need to reframe thinking about the role of medicine sellers in developing country health systems. METHODS: We used in-depth interviews to explore perceptions of medicine seller roles among a restricted random sample of …
Failure to Detect Simian Immunodeficiency Virus Infection in a Large Cameroonian Cohort with High Non-human Primate Exposure
As a clinician, you are not managing lab results, you are managing the patient
Potent antiplasmodial extracts from Cameroonian Annonaceae
Antiplasmodial activity of extracts from seven medicinal plants used in malaria treatment in Cameroon
As a clinician, you are not managing lab results, you are managing the patient
Medicine sellers’ perspectives on their role in providing health care in North-West Cameroon
BACKGROUND: Increasing recognition of the importance of medicine sellers in low-resource settings has emerged alongside assumptions that their motives and capacities primarily relate to profit maximization. This article suggests a need to reframe thinking about the role of medicine sellers in developing country health systems. METHODS: We used in-depth interviews to explore perceptions of medicine seller roles among a restricted random sample of …
Antiplasmodial activity of extracts from seven medicinal plants used in malaria treatment in Cameroon
Potent antiplasmodial extracts from Cameroonian Annonaceae
Failure to Detect Simian Immunodeficiency Virus Infection in a Large Cameroonian Cohort with High Non-human Primate Exposure
As a clinician, you are not managing lab results, you are managing the patient
Medicine sellers’ perspectives on their role in providing health care in North-West Cameroon
BACKGROUND: Increasing recognition of the importance of medicine sellers in low-resource settings has emerged alongside assumptions that their motives and capacities primarily relate to profit maximization. This article suggests a need to reframe thinking about the role of medicine sellers in developing country health systems. METHODS: We used in-depth interviews to explore perceptions of medicine seller roles among a restricted random sample of …
What determines providers' stated preference for the treatment of uncomplicated malaria
As agents for their patients, providers often make treatment decisions on behalf of patients, and their choices can affect health outcomes. However, providers operate within a network of relationships and are agents not only for their patients, but also other health sector actors, such as their employer, the Ministry of Health, and pharmaceutical suppliers. Providers' stated preferences for the treatment of uncomplicated malaria were examined to …
Mind the gap
BACKGROUND: Artemisinin combination therapy (ACT) has been the first-line treatment for uncomplicated malaria in Cameroon since 2004 and Nigeria since 2005, though many febrile patients receive less effective antimalarials. Patients often rely on providers to select treatment, and interventions are needed to improve providers' practice and encourage them to adhere to clinical guidelines. METHODS: Providers' adherence to malaria treatment guidelin…
Assessing Asymptomatic Malaria Carriage of Plasmodium falciparum and Non-falciparum Species in Children Resident in Nkolbisson, Yaoundé, Cameroon
Malaria is still a threat to public health as it remains the first endemic disease in the world. It is a pervasive parasitic disease in tropical and subtropical regions where asymptomatic malaria infection among humans serves as a significant reservoir for transmission. A rapid and correct diagnosis is considered to be an important strategy in the control of the disease especially in children, who are the most vulnerable group. This study assesse…
The R21 malaria vaccine
Malaria impacts millions of lives, mostly in continental Africa, and especially so in the WHO African Region, where 233 million cases accounted for about 94% of global cases in 2022 [1].Progress in curbing malaria has somewhat plateaued since 2015 [2, 3] due to factors that include drug and insecticide resistance, poor availability of rapid diagnostic tests (RDTs) and artemisinin-based combination therapies (ACTs), and socio-behavior factors [3].…
Effectiveness of malaria chemoprevention in the first two years of life in Cameroon and Côte d’Ivoire compared to standard of care
Cameroon - NCT05889052; Côte d'Ivoire - NCT05856357
Oxidative stress in malaria and typhoid fever
Oxidative stress is a key factor in the pathogenesis of many infectious diseases, including typhoid fever and malaria. Co-infection with these diseases poses a particular challenge, as both are associated with increased production of reactive species that can damage tissues, trigger oxidative stress, and exacerbate disease. To cope with this oxidative insult, cells have a defense system consisting of antioxidant molecules that can terminate the o…
Malaria (9 works) · Malaria Research and Control (9 works) · Medicine (9 works) · Environmental health (6 works) · Immunology (6 works) · Mosquito-borne diseases and control (5 works) · Population (5 works) · Biology (4 works) · Global Maternal and Child Health (4 works) · Plasmodium falciparum (4 works)