Sarah J Neal Webb
Biographic Data
| ID | 232531 |
|---|---|
| NAME | Sarah J Neal Webb |
| GIVEN NAMES | Sarah J Neal |
| FAMILY NAME | Webb |
| SIGNATURE | WEBB S J N |
| AFFILIATIONS | The University of Texas MD Anderson Cancer Center Michale E. Keeling Center for Comparative Medicine and Research Bastrop Texas |
| ORCID | 0000-0001-9393-3528 |
| VERIFIED | Yes |
| TOTAL WORKS | 9 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 9 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2016 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Metabolic Biomarkers in Captive Olive Baboons ( Papio anubis )
Diabetic patients are at an increased risk for neurodegeneration, neuroinflammation, and cognitive impairment, likely due to insulin dysregulation and subsequent hyperglycemia in the brain. This leads to cell apoptosis, amyloid beta accumulation, and tau hyperphosphorylation, all hallmarks of Alzheimer's disease and related dementias (ADRD). Baboons show neurological hallmarks of ADRD, including age‐dependent tau pathology in neurons and glial ce…
Neutrophil to lymphocyte ratio in captive olive baboons ( Papio anubis )
In apes and humans, neutrophil to lymphocyte ratio (NLR) can be used as a predictive indicator of a variety of clinical conditions, longevity, and physiological stress. In chimpanzees specifically, NLR systematically varies with age, rearing, sex, and premature death, indicating that NLR may be a useful diagnostic tool in assessing primate health. To date, just one very recent study has investigated NLR in old world monkeys and found lower NLR in…
Age‐related changes in chimpanzee ( Pan troglodytes ) cognition
Chimpanzees are the species most closely related to humans, yet age‐related changes in brain and cognition remain poorly understood. The lack of studies on age‐related changes in cognition in chimpanzees is particularly unfortunate in light of the recent evidence demonstrating that this species naturally develops Alzheimer's disease (AD) neuropathology. Here, we tested 213 young, middle‐aged, and elderly captive chimpanzees on the primate cogniti…
Validation and utility of a body condition scoring system for chimpanzees ( Pan troglodytes )
Obesity is a problem in captive chimpanzee colonies that can lead to increased risk for disease; therefore, implementation of effective weight management strategies is imperative. To properly implement a weight management program, captive managers should be able to noninvasively identify and assess overweight or obese individuals. Traditional means of categorizing obese individuals involve sedating the animals to obtain body weights or skin fold …
The implementation and initial evaluation of a physical therapy program for captive chimpanzees ( Pan troglodytes )
Due to advances in captive nonhuman primate (NHP) medical care, the number of geriatric chimpanzees (≥35‐years old) is growing. With old age comes a variety of physical conditions, including arthritis, stroke, and mobility impairments. Programs aimed at enhancing the welfare of geriatric chimpanzees are now quite common, but there are few published empirical evaluations of the efficacy of such programs. The current study aimed to create, implemen…
Does group size matter? Captive chimpanzee ( Pan troglodytes ) behavior as a function of group size and composition
The National Institutes of Health and the Association of Zoos and Aquariums recommend that captive chimpanzees be housed in multi-male, multi-female, age-diverse groups of no less than seven individuals. These recommendations are rooted in the idea that captive chimpanzee groups should be modeled after free-ranging, wild, fission-fusion chimpanzee societies. However, captive chimpanzees do not face the environmental pressures faced by wild chimpa…
Primatologists
Captive chimpanzee ( Pan troglodytes ) behavior as a function of space per animal and enclosure type
animal. Several studies have investigated chimpanzee behavior in relation to space per animal, but only two studies have examined these variables while attempting to hold environmental complexity constant. Both have found few, if any, significant differences in behavior associated with increased space per animal. The NIH does not provide recommendations pertaining to enclosure type. Although PrimadomesTM and corrals are considered acceptable FACE…
Scratching under positive and negative arousal in common marmosets ( Callithrix jacchus )
Scratching has been widely used as an indicator of anxiety in many primate species. However, a handful of studies have shown no change in scratching under anxiety-provoking circumstances. In addition, the existing literature has investigated scratching only in relation to negative arousal (i.e., anxiety), even though anxiety and excitement (positive arousal) share important physiological and behavioral correlates, including increased heart rate, …
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Scratching under positive and negative arousal in common marmosets ( Callithrix jacchus )
Scratching has been widely used as an indicator of anxiety in many primate species. However, a handful of studies have shown no change in scratching under anxiety-provoking circumstances. In addition, the existing literature has investigated scratching only in relation to negative arousal (i.e., anxiety), even though anxiety and excitement (positive arousal) share important physiological and behavioral correlates, including increased heart rate, …
Captive chimpanzee ( Pan troglodytes ) behavior as a function of space per animal and enclosure type
animal. Several studies have investigated chimpanzee behavior in relation to space per animal, but only two studies have examined these variables while attempting to hold environmental complexity constant. Both have found few, if any, significant differences in behavior associated with increased space per animal. The NIH does not provide recommendations pertaining to enclosure type. Although PrimadomesTM and corrals are considered acceptable FACE…
Does group size matter? Captive chimpanzee ( Pan troglodytes ) behavior as a function of group size and composition
The National Institutes of Health and the Association of Zoos and Aquariums recommend that captive chimpanzees be housed in multi-male, multi-female, age-diverse groups of no less than seven individuals. These recommendations are rooted in the idea that captive chimpanzee groups should be modeled after free-ranging, wild, fission-fusion chimpanzee societies. However, captive chimpanzees do not face the environmental pressures faced by wild chimpa…
Primatologists
Validation and utility of a body condition scoring system for chimpanzees ( Pan troglodytes )
Obesity is a problem in captive chimpanzee colonies that can lead to increased risk for disease; therefore, implementation of effective weight management strategies is imperative. To properly implement a weight management program, captive managers should be able to noninvasively identify and assess overweight or obese individuals. Traditional means of categorizing obese individuals involve sedating the animals to obtain body weights or skin fold …
The implementation and initial evaluation of a physical therapy program for captive chimpanzees ( Pan troglodytes )
Due to advances in captive nonhuman primate (NHP) medical care, the number of geriatric chimpanzees (≥35‐years old) is growing. With old age comes a variety of physical conditions, including arthritis, stroke, and mobility impairments. Programs aimed at enhancing the welfare of geriatric chimpanzees are now quite common, but there are few published empirical evaluations of the efficacy of such programs. The current study aimed to create, implemen…
Age‐related changes in chimpanzee ( Pan troglodytes ) cognition
Chimpanzees are the species most closely related to humans, yet age‐related changes in brain and cognition remain poorly understood. The lack of studies on age‐related changes in cognition in chimpanzees is particularly unfortunate in light of the recent evidence demonstrating that this species naturally develops Alzheimer's disease (AD) neuropathology. Here, we tested 213 young, middle‐aged, and elderly captive chimpanzees on the primate cogniti…
Neutrophil to lymphocyte ratio in captive olive baboons ( Papio anubis )
In apes and humans, neutrophil to lymphocyte ratio (NLR) can be used as a predictive indicator of a variety of clinical conditions, longevity, and physiological stress. In chimpanzees specifically, NLR systematically varies with age, rearing, sex, and premature death, indicating that NLR may be a useful diagnostic tool in assessing primate health. To date, just one very recent study has investigated NLR in old world monkeys and found lower NLR in…
Metabolic Biomarkers in Captive Olive Baboons ( Papio anubis )
Diabetic patients are at an increased risk for neurodegeneration, neuroinflammation, and cognitive impairment, likely due to insulin dysregulation and subsequent hyperglycemia in the brain. This leads to cell apoptosis, amyloid beta accumulation, and tau hyperphosphorylation, all hallmarks of Alzheimer's disease and related dementias (ADRD). Baboons show neurological hallmarks of ADRD, including age‐dependent tau pathology in neurons and glial ce…
Biology (5 works) · Primate Behavior and Ecology (5 works) · Psychology (5 works) · Zoology (5 works) · Animal Behavior and Welfare Studies (4 works) · Ecology (4 works) · Medicine (4 works) · Troglodytes (4 works) · Human-Animal Interaction Studies (3 works) · Primate (3 works)