Nick Patterson
Datos Biográficos
| ID | 239248 |
|---|---|
| NOMBRE | Nick Patterson |
| NOMBRES | Nick |
| APELLIDO | Patterson |
| FIRMA | PATTERSON N |
| AFILIACIONES | Broad Institute |
| ORCID | 0000-0003-0302-684X |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 28 |
| TOTAL DE CITAS | 10 |
| TOTAL COMO AUTOR | 28 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2004 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2021 |
| ÍNDICE H | 2 |
Combining ancient DNA and radiocarbon dating data to increase chronological accuracy
The formation of human populations in South and Central Asia
Ancient human movements through Asia Ancient DNA has allowed us to begin tracing the history of human movements across the globe. Narasimhan et al. identify a complex pattern of human migrations and admixture events in South and Central Asia by performing genetic analysis of more than 500 people who lived over the past 8000 years (see the Perspective by Schaefer and Shapiro). They establish key phases in the population prehistory of Eurasia, incl…
The genomic history of the Iberian Peninsula over the past 8000 years
Genomics of the Iberian Peninsula Ancient DNA studies have begun to help us understand the genetic history and movements of people across the globe. Focusing on the Iberian Peninsula, Olalde et al. report genome-wide data from 271 ancient individuals from Iberia (see the Perspective by Vander Linden). The findings provide a comprehensive genetic time transect of the region. Linguistics analysis and genetic analysis of archaeological human remains…
The genomic history of southeastern Europe
The Beaker phenomenon and the genomic transformation of northwest Europe
Reconstructing the Deep Population History of Central and South America
We report genome-wide ancient DNA from 49 individuals forming four parallel time transects in Belize, Brazil, the Central Andes, and the Southern Cone, each dating to at least ∼9,000 years ago. The common ancestral population radiated rapidly from just one of the two early branches that contributed to Native Americans today. We document two previously unappreciated streams of gene flow between North and South America. One affected the Central And…
The Simons Genome Diversity Project
Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human reference genome. Our analysis reveals key features of the landscape of human genome variation, including that the rate of accumulation of mutations has accelerated by about 5% in non-Africans compared to Africans since divergenc…
Genomic insights into the origin of farming in the ancient Near East
Genomic insights into the peopling of the Southwest Pacific
The genetic history of Ice Age Europe
Massive migration from the steppe was a source for Indo-European languages in Europe
Genome-wide patterns of selection in 230 ancient Eurasians
An early modern human from Romania with a recent Neanderthal ancestor
Genetic evidence for two founding populations of the Americas
An atlas of genetic correlations across human diseases and traits
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
The genomic landscape of Neanderthal ancestry in present-day humans
Ancient human genomes suggest three ancestral populations for present-day Europeans
The complete genome sequence of a Neanderthal from the Altai Mountains
Is Poverty in Our Genes
We present a critique of a paper written by two economists, Quamrul Ashraf and Oded Galor, which is forthcoming in the American Economic Review and which was uncritically highlighted in Science magazine. Their paper claims there is a causal effect of genetic diversity on economic success, positing that too much or too little genetic diversity constrains development. In particular, they argue that "the high degree of diversity among African popula…
Reconstructing Native American population history
Ancient Admixture in Human History
Population mixture is an important process in biology. We present a suite of methods for learning about population mixtures, implemented in a software package called ADMIXTOOLS, that support formal tests for whether mixture occurred and make it possible to infer proportions and dates of mixture. We also describe the development of a new single nucleotide polymorphism (SNP) array consisting of 629,433 sites with clearly documented ascertainment th…
Denisova Admixture and the First Modern Human Dispersals into Southeast Asia and Oceania
Genetic history of an archaic hominin group from Denisova Cave in Siberia
Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This individual is from a group that shares a common origin with Neanderthals. This population was not involved in the putative gene flow from Neanderthals into Eurasians; however, the data suggest that it contributed 4–6% of its genetic material to the genomes of present-day Melanesians…
A Draft Sequence of the Neandertal Genome
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of Europe and western Asia before disappearing 30,000 years ago. We present a draft sequence of the Neandertal genome composed of more than 4 billion nucleotides from three individuals. Comparisons of the Neandertal genome to the genomes of five present-day humans from different parts of the world identify a number of genomic regions that may have been aff…
Is Poverty in Our Genes
We present a critique of a paper written by two economists, Quamrul Ashraf and Oded Galor, which is forthcoming in the American Economic Review and which was uncritically highlighted in Science magazine. Their paper claims there is a causal effect of genetic diversity on economic success, positing that too much or too little genetic diversity constrains development. In particular, they argue that "the high degree of diversity among African popula…
Combining ancient DNA and radiocarbon dating data to increase chronological accuracy
Genetic Signatures of Strong Recent Positive Selection at the Lactase Gene
Population Structure and Eigenanalysis
Current methods for inferring population structure from genetic data do not provide formal significance tests for population differentiation. We discuss an approach to studying population structure (principal components analysis) that was first applied to genetic data by Cavalli-Sforza and colleagues. We place the method on a solid statistical footing, using results from modern statistics to develop formal significance tests. We also uncover a ge…
Reconstructing Indian population history
Genetic history of an archaic hominin group from Denisova Cave in Siberia
Using DNA extracted from a finger bone found in Denisova Cave in southern Siberia, we have sequenced the genome of an archaic hominin to about 1.9-fold coverage. This individual is from a group that shares a common origin with Neanderthals. This population was not involved in the putative gene flow from Neanderthals into Eurasians; however, the data suggest that it contributed 4–6% of its genetic material to the genomes of present-day Melanesians…
A Draft Sequence of the Neandertal Genome
Neandertals, the closest evolutionary relatives of present-day humans, lived in large parts of Europe and western Asia before disappearing 30,000 years ago. We present a draft sequence of the Neandertal genome composed of more than 4 billion nucleotides from three individuals. Comparisons of the Neandertal genome to the genomes of five present-day humans from different parts of the world identify a number of genomic regions that may have been aff…
Denisova Admixture and the First Modern Human Dispersals into Southeast Asia and Oceania
Reconstructing Native American population history
Ancient Admixture in Human History
Population mixture is an important process in biology. We present a suite of methods for learning about population mixtures, implemented in a software package called ADMIXTOOLS, that support formal tests for whether mixture occurred and make it possible to infer proportions and dates of mixture. We also describe the development of a new single nucleotide polymorphism (SNP) array consisting of 629,433 sites with clearly documented ascertainment th…
Is Poverty in Our Genes
We present a critique of a paper written by two economists, Quamrul Ashraf and Oded Galor, which is forthcoming in the American Economic Review and which was uncritically highlighted in Science magazine. Their paper claims there is a causal effect of genetic diversity on economic success, positing that too much or too little genetic diversity constrains development. In particular, they argue that "the high degree of diversity among African popula…
The genomic landscape of Neanderthal ancestry in present-day humans
Ancient human genomes suggest three ancestral populations for present-day Europeans
The complete genome sequence of a Neanderthal from the Altai Mountains
Massive migration from the steppe was a source for Indo-European languages in Europe
Genome-wide patterns of selection in 230 ancient Eurasians
An early modern human from Romania with a recent Neanderthal ancestor
Genetic evidence for two founding populations of the Americas
An atlas of genetic correlations across human diseases and traits
LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
The Simons Genome Diversity Project
Here we report the Simons Genome Diversity Project data set: high quality genomes from 300 individuals from 142 diverse populations. These genomes include at least 5.8 million base pairs that are not present in the human reference genome. Our analysis reveals key features of the landscape of human genome variation, including that the rate of accumulation of mutations has accelerated by about 5% in non-Africans compared to Africans since divergenc…
Genomic insights into the origin of farming in the ancient Near East
Genomic insights into the peopling of the Southwest Pacific
The genetic history of Ice Age Europe
The genomic history of southeastern Europe
The Beaker phenomenon and the genomic transformation of northwest Europe
Reconstructing the Deep Population History of Central and South America
We report genome-wide ancient DNA from 49 individuals forming four parallel time transects in Belize, Brazil, the Central Andes, and the Southern Cone, each dating to at least ∼9,000 years ago. The common ancestral population radiated rapidly from just one of the two early branches that contributed to Native Americans today. We document two previously unappreciated streams of gene flow between North and South America. One affected the Central And…
Biology (25 obras) · Geography (21 obras) · Forensic and Genetic Research (20 obras) · Demography (17 obras) · Evolutionary biology (17 obras) · Population (17 obras) · Archaeology (16 obras) · Genetics (16 obras) · Gene (14 obras) · History (13 obras)