Olia Papacosta
Datos Biográficos
| ID | 247484 |
|---|---|
| NOMBRE | Olia Papacosta |
| NOMBRES | Olia |
| APELLIDO | Papacosta |
| FIRMA | PAPACOSTA O |
| AFILIACIONES | University College London |
| ORCID | 0000-0001-8781-6747 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 14 |
| TOTAL DE CITAS | 14 |
| TOTAL COMO AUTOR | 14 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1988 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2020 |
| ÍNDICE H | 2 |
Trajectories of physical activity from midlife to old age and associations with subsequent cardiovascular disease and all-cause mortality
INTRODUCTION: It is well established that physical activity (PA) protects against mortality and morbidity, but how long-term patterns of PA are associated with mortality and cardiovascular disease (CVD) remains unclear. METHODS: 3231 men recruited to the British Regional Heart Study, a prospective cohort study, reported usual PA levels at baseline in 1978-1980 (aged 40-59 years) and at 12-year, 16-year and 20-year follow ups. Twenty-year trajecto…
Chronic kidney disease, cardiovascular risk markers and total mortality in older men
Background It remains uncertain whether cystatin C is a superior marker of renal function than creatinine in older adults. We have investigated the association between estimated glomerular filtration rate (eGFR) using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations based on creatinine (CKD-EPIcr) and cystatin C (CKD-EPIcys), and cardiovascular risk markers and mortality in older adults. Methods This is a cross-sectional …
The influence of neighbourhood-level socioeconomic deprivation on cardiovascular disease mortality in older age
BACKGROUND: Evidence from longitudinal studies on the influence of neighbourhood socioeconomic factors in older age on cardiovascular disease (CVD) mortality is limited. We aimed to investigate the prospective association of neighbourhood-level deprivation in later life with CVD mortality, and assess the underlying role of established cardiovascular risk factors. METHODS: A socially representative cohort of 3924 men, aged 60-79 years in 1998-2000…
OP80 Inequalities in Heart Failure in Older Age
Background Few studies have examined the prospective associations between socioeconomic measures and incident heart failure, and little is known about possible mechanisms underlying the relationship. The aim of this study was to investigate the association of socioeconomic measures with incident heart failure in older adults and to examine possible underlying pathways. Methods A socially and geographically representative cohort of men aged 60–79 …
Class and lifestyle ‘lock‐in’ among middle‐aged and older men
Health lifestyles are collective patterns of health risk behaviour that develop within a social habitus. An important area for research is the extent to which health lifestyles become more individualised over time and as people age, or whether health lifestyles remain socially structured. This article presents findings from a Multiple Correspondence Analysis of the British Regional Heart Study. Our findings suggest that smoking and alcohol use re…
Year trends in major coronary risk factors in older British men
the ''drift''. Our predictions are that stroke deaths are likely to continue to decrease up to at least 2015. For 2015, our predictions of deaths from stroke varied from 34 429 to 46 538 (compared with 47 213 deaths in 2005) under the different plausible model scenarios. We also noted that there were some potentially interesting trends in mortality amongst recent birth cohorts. In particular, mortality was higher in older age groups, but the diff…
Prediction scores to identify older adults at high risk for type 2 diabetes
The greatest relative increase in type 2 diabetes (T2DM) prevalence in developed countries thought likely to occur over the next 25 years will be in the over 65 age group. The aim of this study was to examine the effectiveness of both simple strategies based on simple clinical parameters (suitable for use in primary care) and more complex scores involving blood markers to identify older individuals at high risk of developing T2DM. A
Carboxyhaemoglobin levels and their determinants in older British men
An appreciable proportion of men have COHb levels of 2.5% or more at which symptomatic effects may occur, though very high levels are uncommon. The results confirm that smoking (particularly cigarette smoking) is the dominant influence on COHb levels
Sex differences in body fat distribution and carotid intima media thickness
Objective: To determine the role of central adiposity in explaining sex differences in carotid intima media thickness (IMT). Design: Cross sectional survey. Setting: Two British towns. Participants: 800 men and women aged 56–75 years. Main outcome measures: Carotid IMT. Results: There was a continuous linear association between waist-hip ratio and IMT in both men and women. The magnitude of the association between waist to hip ratio and IMT was i…
Social inequalities and disability in older men
Respiratory effects of lowering tar and nicotine levels of cigarettes smoked by young male middle tar smokers. I. Design of a randomised controlled trial
STUDY OBJECTIVE--The aim was to investigate the effect on respiratory health of male middle tar smokers changing the tar and nicotine levels of the cigarettes they smoke for a six month period. DESIGN--This was a randomised controlled trial. Middle tar smokers were randomly allocated to smoke one of three different types of cigarette (low tar, middle nicotine; middle tar, middle nicotine; and low tar, low nicotine) in place of their usual cigaret…
Childhood blood pressure, body build, and birthweight
STUDY OBJECTIVE--The aim was to examine whether blood pressure, body build, and birthweight differ between areas of England and Wales with widely differing adult cardiovascular mortality rates. DESIGN--This was a cross sectional survey of children in five towns with exceptionally high and five towns with exceptionally low current adult cardiovascular mortality. SETTING--The study was a school based survey. SUBJECTS--3842 children aged 5.0-7.5 yea…
Respiratory effects of lowering tar and nicotine levels of cigarettes smoked by young male middle tar smokers. II. Results of a randomised controlled trial
STUDY OBJECTIVE--The aim was to investigate the effect on respiratory health of male middle tar smokers changing the tar and nicotine levels of the cigarettes they smoke for a six month period. DESIGN--This was a randomised controlled trial. Middle tar smokers were randomly allocated to smoke one of three different types of cigarette (low tar, middle nicotine; middle tar, middle nicotine; and low tar, low nicotine) in place of their usual cigaret…
Repeatability of a questionnaire to assess respiratory symptoms in smokers
To evaluate the repeatability of a questionnaire designed to assess change in respiratory symptoms 90 smokers were interviewed on two occasions. The questionnaire included questions from the Medical Research Council questionnaire on respiratory symptoms, questions on acute chest illness and cough and phlegm production in the preceding two weeks, a modification of Field's card system for estimating frequency of cough, and an objective assessment o…
Social inequalities and disability in older men
Class and lifestyle ‘lock‐in’ among middle‐aged and older men
Health lifestyles are collective patterns of health risk behaviour that develop within a social habitus. An important area for research is the extent to which health lifestyles become more individualised over time and as people age, or whether health lifestyles remain socially structured. This article presents findings from a Multiple Correspondence Analysis of the British Regional Heart Study. Our findings suggest that smoking and alcohol use re…
The influence of neighbourhood-level socioeconomic deprivation on cardiovascular disease mortality in older age
BACKGROUND: Evidence from longitudinal studies on the influence of neighbourhood socioeconomic factors in older age on cardiovascular disease (CVD) mortality is limited. We aimed to investigate the prospective association of neighbourhood-level deprivation in later life with CVD mortality, and assess the underlying role of established cardiovascular risk factors. METHODS: A socially representative cohort of 3924 men, aged 60-79 years in 1998-2000…
Respiratory effects of lowering tar and nicotine levels of cigarettes smoked by young male middle tar smokers. I. Design of a randomised controlled trial
STUDY OBJECTIVE--The aim was to investigate the effect on respiratory health of male middle tar smokers changing the tar and nicotine levels of the cigarettes they smoke for a six month period. DESIGN--This was a randomised controlled trial. Middle tar smokers were randomly allocated to smoke one of three different types of cigarette (low tar, middle nicotine; middle tar, middle nicotine; and low tar, low nicotine) in place of their usual cigaret…
Childhood blood pressure, body build, and birthweight
STUDY OBJECTIVE--The aim was to examine whether blood pressure, body build, and birthweight differ between areas of England and Wales with widely differing adult cardiovascular mortality rates. DESIGN--This was a cross sectional survey of children in five towns with exceptionally high and five towns with exceptionally low current adult cardiovascular mortality. SETTING--The study was a school based survey. SUBJECTS--3842 children aged 5.0-7.5 yea…
Respiratory effects of lowering tar and nicotine levels of cigarettes smoked by young male middle tar smokers. II. Results of a randomised controlled trial
STUDY OBJECTIVE--The aim was to investigate the effect on respiratory health of male middle tar smokers changing the tar and nicotine levels of the cigarettes they smoke for a six month period. DESIGN--This was a randomised controlled trial. Middle tar smokers were randomly allocated to smoke one of three different types of cigarette (low tar, middle nicotine; middle tar, middle nicotine; and low tar, low nicotine) in place of their usual cigaret…
Repeatability of a questionnaire to assess respiratory symptoms in smokers
To evaluate the repeatability of a questionnaire designed to assess change in respiratory symptoms 90 smokers were interviewed on two occasions. The questionnaire included questions from the Medical Research Council questionnaire on respiratory symptoms, questions on acute chest illness and cough and phlegm production in the preceding two weeks, a modification of Field's card system for estimating frequency of cough, and an objective assessment o…
Respiratory effects of lowering tar and nicotine levels of cigarettes smoked by young male middle tar smokers. I. Design of a randomised controlled trial
STUDY OBJECTIVE--The aim was to investigate the effect on respiratory health of male middle tar smokers changing the tar and nicotine levels of the cigarettes they smoke for a six month period. DESIGN--This was a randomised controlled trial. Middle tar smokers were randomly allocated to smoke one of three different types of cigarette (low tar, middle nicotine; middle tar, middle nicotine; and low tar, low nicotine) in place of their usual cigaret…
Childhood blood pressure, body build, and birthweight
STUDY OBJECTIVE--The aim was to examine whether blood pressure, body build, and birthweight differ between areas of England and Wales with widely differing adult cardiovascular mortality rates. DESIGN--This was a cross sectional survey of children in five towns with exceptionally high and five towns with exceptionally low current adult cardiovascular mortality. SETTING--The study was a school based survey. SUBJECTS--3842 children aged 5.0-7.5 yea…
Respiratory effects of lowering tar and nicotine levels of cigarettes smoked by young male middle tar smokers. II. Results of a randomised controlled trial
STUDY OBJECTIVE--The aim was to investigate the effect on respiratory health of male middle tar smokers changing the tar and nicotine levels of the cigarettes they smoke for a six month period. DESIGN--This was a randomised controlled trial. Middle tar smokers were randomly allocated to smoke one of three different types of cigarette (low tar, middle nicotine; middle tar, middle nicotine; and low tar, low nicotine) in place of their usual cigaret…
Sex differences in body fat distribution and carotid intima media thickness
Objective: To determine the role of central adiposity in explaining sex differences in carotid intima media thickness (IMT). Design: Cross sectional survey. Setting: Two British towns. Participants: 800 men and women aged 56–75 years. Main outcome measures: Carotid IMT. Results: There was a continuous linear association between waist-hip ratio and IMT in both men and women. The magnitude of the association between waist to hip ratio and IMT was i…
Social inequalities and disability in older men
Carboxyhaemoglobin levels and their determinants in older British men
An appreciable proportion of men have COHb levels of 2.5% or more at which symptomatic effects may occur, though very high levels are uncommon. The results confirm that smoking (particularly cigarette smoking) is the dominant influence on COHb levels
Year trends in major coronary risk factors in older British men
the ''drift''. Our predictions are that stroke deaths are likely to continue to decrease up to at least 2015. For 2015, our predictions of deaths from stroke varied from 34 429 to 46 538 (compared with 47 213 deaths in 2005) under the different plausible model scenarios. We also noted that there were some potentially interesting trends in mortality amongst recent birth cohorts. In particular, mortality was higher in older age groups, but the diff…
Prediction scores to identify older adults at high risk for type 2 diabetes
The greatest relative increase in type 2 diabetes (T2DM) prevalence in developed countries thought likely to occur over the next 25 years will be in the over 65 age group. The aim of this study was to examine the effectiveness of both simple strategies based on simple clinical parameters (suitable for use in primary care) and more complex scores involving blood markers to identify older individuals at high risk of developing T2DM. A
Class and lifestyle ‘lock‐in’ among middle‐aged and older men
Health lifestyles are collective patterns of health risk behaviour that develop within a social habitus. An important area for research is the extent to which health lifestyles become more individualised over time and as people age, or whether health lifestyles remain socially structured. This article presents findings from a Multiple Correspondence Analysis of the British Regional Heart Study. Our findings suggest that smoking and alcohol use re…
OP80 Inequalities in Heart Failure in Older Age
Background Few studies have examined the prospective associations between socioeconomic measures and incident heart failure, and little is known about possible mechanisms underlying the relationship. The aim of this study was to investigate the association of socioeconomic measures with incident heart failure in older adults and to examine possible underlying pathways. Methods A socially and geographically representative cohort of men aged 60–79 …
The influence of neighbourhood-level socioeconomic deprivation on cardiovascular disease mortality in older age
BACKGROUND: Evidence from longitudinal studies on the influence of neighbourhood socioeconomic factors in older age on cardiovascular disease (CVD) mortality is limited. We aimed to investigate the prospective association of neighbourhood-level deprivation in later life with CVD mortality, and assess the underlying role of established cardiovascular risk factors. METHODS: A socially representative cohort of 3924 men, aged 60-79 years in 1998-2000…
Chronic kidney disease, cardiovascular risk markers and total mortality in older men
Background It remains uncertain whether cystatin C is a superior marker of renal function than creatinine in older adults. We have investigated the association between estimated glomerular filtration rate (eGFR) using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations based on creatinine (CKD-EPIcr) and cystatin C (CKD-EPIcys), and cardiovascular risk markers and mortality in older adults. Methods This is a cross-sectional …
Trajectories of physical activity from midlife to old age and associations with subsequent cardiovascular disease and all-cause mortality
INTRODUCTION: It is well established that physical activity (PA) protects against mortality and morbidity, but how long-term patterns of PA are associated with mortality and cardiovascular disease (CVD) remains unclear. METHODS: 3231 men recruited to the British Regional Heart Study, a prospective cohort study, reported usual PA levels at baseline in 1978-1980 (aged 40-59 years) and at 12-year, 16-year and 20-year follow ups. Twenty-year trajecto…
Medicine (14 obras) · Internal Medicine (10 obras) · Internal Medicine (9 obras) · Demography (8 obras) · Gerontology (8 obras) · Environmental health (7 obras) · Gerontology (7 obras) · Cohort study (5 obras) · Health disparities and outcomes (5 obras) · Cohort (4 obras)