Krista J Siefried
Biographic Data
| ID | 2788890 |
|---|---|
| NAME | Krista J Siefried |
| GIVEN NAMES | Krista J |
| FAMILY NAME | Siefried |
| SIGNATURE | SIEFRIED K J |
| AFFILIATIONS | UNSW Sydney |
| ORCID | 0000-0002-6534-3325 |
| VERIFIED | Yes |
| TOTAL WORKS | 24 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 24 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2021 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Expanding Access to Addiction Medicine Specialist Care in Regional New South Wales, Australia Through Telehealth
Exploring the Utility and Appropriateness of Dose Thresholds for Issuing of Public Drug Alerts on High‐Dose MDMA
The Emergence of Novel Benzodiazepines in Australia, Evidence, Alerts, Clinical Management and Harm Reduction—A Narrative Review
Digital health interventions for people who use methamphetamine
DHIs show promise for people who use methamphetamine. While current evidence supports feasibility and acceptability, clinical outcomes are variable. High attrition and engagement challenges persist. Heterogeneity in study designs, measures, and reporting limits comparability. Future research should explore long-term outcomes, hybrid models, and co-designed approaches with a focus on gender and equity. With further development, DHIs may play a val…
Incorporating experiential reports provided by people who use drugs into drug-related early warning systems
Sex, Methamphetamine, and a Surge in Syphilis Among Women and Men Who Have Sex With Women
Globally rates of syphilis have been increasing since 1990 and, historically transmission has predominated among gay, bisexual, and men who have sex with men (GBMSM). In the past decade, transmission has increased among women and men who have sex with women (MSW). This led Australia to declare syphilis a communicable disease of national significance in August 2025. In this commentary, we consider the implications of these developments on concepti…
Co-design of the Australian Prompt Response Network for a public-health focused intersectoral approach to information sharing on emerging drugs of concern
The rapid emergence of new psychoactive substances (NPS) and other emerging drugs of concern presents a significant global public health challenge, necessitating agile and interconnected drug information systems to identify and communicate risks. In Australia, responses have traditionally been localized, lacking a nationally coordinated system to rapidly share information about emerging drug threats. The National Center for Clinical Research on E…
Hydromorphone Hopes
Exploring experiences of talk therapies among gay and bisexual men seeking to reduce or abstain from using crystal methamphetamine in the context of chemsex
From environmental disasters to emerging drugs; a framework to understand, map and assess drug-related early warning systems
Unregulated drug markets are fast expanding and increasingly mediated through digital technologies. In a context of drug prohibition, the composition, potency and effects of substances are not guaranteed which can expose people to potentially fatal risks. There are pronounced concerns about the harms posed by substances such as synthetic opioids like fentanyl and nitazenes. The coordinated activities of stakeholders who attempt to identify, prepa…
Bridging the evidence and the politics
Supervised Injectable Opioid Treatment (SIOT) targets people experiencing opioid dependence who have not benefited from existing treatments. In this population, SIOT has been demonstrated to be efficacious and effective, yet this modality of treatment has only been taken up in a few countries. In this commentary we describe the socio-political context and history to the recent establishment of an implementation trial of injectable hydromorphone i…
Exploring the perceived usefulness of integration support after naturalistic psychedelic experiences in people concerned about their substance use
Background and aimsImproved outcomes for substance use disorders have been described following non-clinical ("naturalistic") psychedelic use. This exploratory study aimed to describe the naturalistic psychedelic experiences of people with substance use concerns and their reported needs and perceived utility of psychosocial support following naturalistic psychedelic use to integrate experiences and achieve positive change. We also explored preferr…
Psilocybin-assisted psychotherapy for methamphetamine dependence
Methamphetamine (MA) dependence leads to severe physical and psychological issues. Current treatments, including psychosocial therapies and residential rehabilitation, face limitations such as high relapse rates, cost, and accessibility issues. As a result, there is an urgent need for novel approaches to treat MA dependence that are effective, affordable, and accessible to patients. Psilocybin, the active component in numerous mushrooms of the Ps…
Participant experiences in a pilot study for methamphetamine withdrawal treatment
The experiences of participants in this clinical trial can be distilled into four meta-themes: agency, caring-trust, safety, and communication. Participants spontaneously linked these experiences with a capacity to remain enrolled in the study. By considering the experiences of trial participants in clinical trial design, researchers can improve the experiences of future trial participants and facilitate their choice to remain enrolled in clinica…
Methamphetamine and emerging drugs of concern
Health and social characteristics of clients reporting amphetamine type substance use at entry to public alcohol and other drug services in New South Wales, Australia, 2016–2019
Pharmacological treatment for methamphetamine withdrawal
Phenobarbital to manage severe gamma‐hydroxybutyrate withdrawal
A clinical research priority setting study for issues related to the use of methamphetamine and emerging drugs of concern in Australia
Barriers to help‐seeking among music festival attendees in New South Wales, Australia
Correlates of higher‐risk drug‐related behaviours at music festivals in New South Wales, Australia
Playing at the edges, navigating sexual boundaries, and narrating sexual distress; Practices and perspectives of sexuality and gender diverse people who use GHB
Positive strategies to facilitate sexual communication prior to and throughout GHB sex should be reflected in health promotion and service level responses to promote affirmative and continuous consent among people who use GHB for sex. Education initiatives to help people engaged in SDU to recognise and respond to sexual violence if it occurs ought to be prioritised
Controlling for pleasure and risk
Participants' near-ubiquitous experience of GHB overdose highlights ongoing education needs around overdose prevention. Efforts must target people new to GHB use who appeared particularly susceptible to overdose. Inconsistencies in understandings around GHB overdose, the perceived severity of overdose and the differences between GHB and its precursors GBL and 1,4-BD, highlight potential focus areas of future education responses. Further research …
Impact of the removal of patient co-payments for antiretroviral therapy (ART) on out-of-pocket expenditure, adherence and virological failure among Australian adults living with HIV
BACKGROUND: In 2015, New South Wales (Australia) removed patient co-payments for ART of HIV. We hypothesized the policy change would reduce overall out-of-pocket (OOP) healthcare expenditure, improve ART adherence, and better maintain HIV suppression. METHODS: Using data from a national, 2-year prospective study of adults with HIV on ART (n=364) (2013-2017), we compared OOP healthcare expenditure, ART adherence, and virological failure (VF) in pa…
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Impact of the removal of patient co-payments for antiretroviral therapy (ART) on out-of-pocket expenditure, adherence and virological failure among Australian adults living with HIV
BACKGROUND: In 2015, New South Wales (Australia) removed patient co-payments for ART of HIV. We hypothesized the policy change would reduce overall out-of-pocket (OOP) healthcare expenditure, improve ART adherence, and better maintain HIV suppression. METHODS: Using data from a national, 2-year prospective study of adults with HIV on ART (n=364) (2013-2017), we compared OOP healthcare expenditure, ART adherence, and virological failure (VF) in pa…
A clinical research priority setting study for issues related to the use of methamphetamine and emerging drugs of concern in Australia
Barriers to help‐seeking among music festival attendees in New South Wales, Australia
Correlates of higher‐risk drug‐related behaviours at music festivals in New South Wales, Australia
Playing at the edges, navigating sexual boundaries, and narrating sexual distress; Practices and perspectives of sexuality and gender diverse people who use GHB
Positive strategies to facilitate sexual communication prior to and throughout GHB sex should be reflected in health promotion and service level responses to promote affirmative and continuous consent among people who use GHB for sex. Education initiatives to help people engaged in SDU to recognise and respond to sexual violence if it occurs ought to be prioritised
Controlling for pleasure and risk
Participants' near-ubiquitous experience of GHB overdose highlights ongoing education needs around overdose prevention. Efforts must target people new to GHB use who appeared particularly susceptible to overdose. Inconsistencies in understandings around GHB overdose, the perceived severity of overdose and the differences between GHB and its precursors GBL and 1,4-BD, highlight potential focus areas of future education responses. Further research …
Methamphetamine and emerging drugs of concern
Health and social characteristics of clients reporting amphetamine type substance use at entry to public alcohol and other drug services in New South Wales, Australia, 2016–2019
Pharmacological treatment for methamphetamine withdrawal
Phenobarbital to manage severe gamma‐hydroxybutyrate withdrawal
Psilocybin-assisted psychotherapy for methamphetamine dependence
Methamphetamine (MA) dependence leads to severe physical and psychological issues. Current treatments, including psychosocial therapies and residential rehabilitation, face limitations such as high relapse rates, cost, and accessibility issues. As a result, there is an urgent need for novel approaches to treat MA dependence that are effective, affordable, and accessible to patients. Psilocybin, the active component in numerous mushrooms of the Ps…
Participant experiences in a pilot study for methamphetamine withdrawal treatment
The experiences of participants in this clinical trial can be distilled into four meta-themes: agency, caring-trust, safety, and communication. Participants spontaneously linked these experiences with a capacity to remain enrolled in the study. By considering the experiences of trial participants in clinical trial design, researchers can improve the experiences of future trial participants and facilitate their choice to remain enrolled in clinica…
Co-design of the Australian Prompt Response Network for a public-health focused intersectoral approach to information sharing on emerging drugs of concern
The rapid emergence of new psychoactive substances (NPS) and other emerging drugs of concern presents a significant global public health challenge, necessitating agile and interconnected drug information systems to identify and communicate risks. In Australia, responses have traditionally been localized, lacking a nationally coordinated system to rapidly share information about emerging drug threats. The National Center for Clinical Research on E…
Hydromorphone Hopes
Exploring experiences of talk therapies among gay and bisexual men seeking to reduce or abstain from using crystal methamphetamine in the context of chemsex
From environmental disasters to emerging drugs; a framework to understand, map and assess drug-related early warning systems
Unregulated drug markets are fast expanding and increasingly mediated through digital technologies. In a context of drug prohibition, the composition, potency and effects of substances are not guaranteed which can expose people to potentially fatal risks. There are pronounced concerns about the harms posed by substances such as synthetic opioids like fentanyl and nitazenes. The coordinated activities of stakeholders who attempt to identify, prepa…
Bridging the evidence and the politics
Supervised Injectable Opioid Treatment (SIOT) targets people experiencing opioid dependence who have not benefited from existing treatments. In this population, SIOT has been demonstrated to be efficacious and effective, yet this modality of treatment has only been taken up in a few countries. In this commentary we describe the socio-political context and history to the recent establishment of an implementation trial of injectable hydromorphone i…
Exploring the perceived usefulness of integration support after naturalistic psychedelic experiences in people concerned about their substance use
Background and aimsImproved outcomes for substance use disorders have been described following non-clinical ("naturalistic") psychedelic use. This exploratory study aimed to describe the naturalistic psychedelic experiences of people with substance use concerns and their reported needs and perceived utility of psychosocial support following naturalistic psychedelic use to integrate experiences and achieve positive change. We also explored preferr…
Expanding Access to Addiction Medicine Specialist Care in Regional New South Wales, Australia Through Telehealth
Exploring the Utility and Appropriateness of Dose Thresholds for Issuing of Public Drug Alerts on High‐Dose MDMA
The Emergence of Novel Benzodiazepines in Australia, Evidence, Alerts, Clinical Management and Harm Reduction—A Narrative Review
Digital health interventions for people who use methamphetamine
DHIs show promise for people who use methamphetamine. While current evidence supports feasibility and acceptability, clinical outcomes are variable. High attrition and engagement challenges persist. Heterogeneity in study designs, measures, and reporting limits comparability. Future research should explore long-term outcomes, hybrid models, and co-designed approaches with a focus on gender and equity. With further development, DHIs may play a val…
Incorporating experiential reports provided by people who use drugs into drug-related early warning systems
Sex, Methamphetamine, and a Surge in Syphilis Among Women and Men Who Have Sex With Women
Globally rates of syphilis have been increasing since 1990 and, historically transmission has predominated among gay, bisexual, and men who have sex with men (GBMSM). In the past decade, transmission has increased among women and men who have sex with women (MSW). This led Australia to declare syphilis a communicable disease of national significance in August 2025. In this commentary, we consider the implications of these developments on concepti…
Medicine (16 works) · Psychology (11 works) · Psychiatry (8 works) · Substance Abuse Treatment and Outcomes (8 works) · HIV, Drug Use, Sexual Risk (7 works) · Opioid Use Disorder Treatment (7 works) · Drug (5 works) · Environmental health (5 works) · Forensic Toxicology and Drug Analysis (5 works) · Internal Medicine (5 works)