Lluís Quintana‐murci
Biographic Data
| ID | 3459947 |
|---|---|
| NAME | Lluís Quintana‐murci |
| GIVEN NAMES | Lluís |
| FAMILY NAME | Quintana‐murci |
| SIGNATURE | MURCI L Q |
| AFFILIATIONS | Centre National de la Recherche Scientifique |
| ORCID | 0000-0003-2429-6320 |
| VERIFIED | Yes |
| TOTAL WORKS | 10 |
| TOTAL CITATIONS | 40 |
| AUTHOR COUNT | 10 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1999 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 4 |
Génomique humaine et évolution
International audience
Génomique humaine et évolution
EnseignementCours – Évolution humaine et génétique des populations (suite)IntroductionDès le début de la génétique moderne, on a distingué quatre facteurs majeurs qui influencent la variabilité génétique : la mutation qui produit de nouveaux types génétiques, la sélection naturelle qui favorise les types génétiques conférant aux individus une meilleure adaptation à l’environnement dans lequel ils évoluent, la dérive génétique qui est l’effet du h…
Génomique humaine et évolution
enseiGnement cours -volution humaine et Gntique des populations et non gntique (i.e., genre, ge, mode de vie) peuvent tre associes des diffrences de rponse l'infection, et comment les variants gntiques associs la variation de l'expression gnique ont t la cible de la slection naturelle. Ce projet nous aidera explorer l'impact de la diversit (pi)gntique sur les variations de rponse immunitaire dans les populations humaines
Lactase Persistence in Central Asia: Phenotype, Genotype, and Evolution
The aim of the present study is to document the evolution of the lactase persistence trait in Central Asia, a geographical area that is thought to have been a region of long-term pastoralism. Several ethnic groups co-exist in this area: Indo-Iranian speakers who are traditionally agriculturist (Tajik) and Turkic speakers who used to be nomadic herders (Kazakh, Karakalpak, Kyrgyz, Turkmen). It was recently demonstrated that horse milking practice …
Genetic traces of east‐to‐west human expansion waves in Eurasia
In this study, we describe the landscape of human demographic expansions in Eurasia using a large continental Y chromosome and mitochondrial DNA dataset. Variation at these two uniparentally‐inherited genetic systems retraces expansions that occurred in the past 60 ky, and shows a clear decrease of expansion ages from east to west Eurasia. To investigate the demographic events at the origin of this westward decrease of expansion ages, the estimat…
A population genetics perspective of the Indus Valley through uniparentally-inherited markers
Analysis of mtDNA and Y-chromosome variation in the Indo-Gangetic plains shows that it was a region where genetic components of different geographical origins (from west, east and south) met. The genetic architecture of the populations now living in the area comprise genetic components dating back to different time-periods during the Palaeolithic and the Neolithic. mtDNA data analysis has demonstrated a number of deep-rooting lineages of Pleistoc…
Where West Meets East: The Complex mtDNA Landscape of the Southwest and Central Asian Corridor
Genetic structure of Mediterranean populations revealed by Y‐chromosome haplotype analysis
The allelic variability at six Y‐chromosome‐specific polymorphisms (YAP, DYS19, DYS389‐I, DYS390, DYS391, and DYS392) was used to generate male‐specific haplotypes in 333 males representing 12 population samples from the region around the Mediterranean sea. Extreme interindividual variation was observed, as more than 160 distinct Y‐chromosome variants could be defined as six‐locus haplotypes. Concomitant with this high variability, low levels of …
Y-Chromosome Analysis in Egypt Suggests a Genetic Regional Continuity in Northeastern Africa
The geographic location of Egypt, at the interface between North Africa, the Middle East, and southern Europe, prompted us to investigate the genetic diversity of this population and its relationship with neighboring populations. To assess the extent to which the modern Egyptian population reflects this intermediate geographic position, ten Unique Event Polymorphisms (UEPs), mapping to the nonrecombining portion of the Y chromosome, have been typ…
Genetic evidence of an early exit of Homo sapiens sapiens from Africa through eastern Africa
Y-Chromosome Analysis in Egypt Suggests a Genetic Regional Continuity in Northeastern Africa
The geographic location of Egypt, at the interface between North Africa, the Middle East, and southern Europe, prompted us to investigate the genetic diversity of this population and its relationship with neighboring populations. To assess the extent to which the modern Egyptian population reflects this intermediate geographic position, ten Unique Event Polymorphisms (UEPs), mapping to the nonrecombining portion of the Y chromosome, have been typ…
Lactase Persistence in Central Asia: Phenotype, Genotype, and Evolution
The aim of the present study is to document the evolution of the lactase persistence trait in Central Asia, a geographical area that is thought to have been a region of long-term pastoralism. Several ethnic groups co-exist in this area: Indo-Iranian speakers who are traditionally agriculturist (Tajik) and Turkic speakers who used to be nomadic herders (Kazakh, Karakalpak, Kyrgyz, Turkmen). It was recently demonstrated that horse milking practice …
Genetic traces of east‐to‐west human expansion waves in Eurasia
In this study, we describe the landscape of human demographic expansions in Eurasia using a large continental Y chromosome and mitochondrial DNA dataset. Variation at these two uniparentally‐inherited genetic systems retraces expansions that occurred in the past 60 ky, and shows a clear decrease of expansion ages from east to west Eurasia. To investigate the demographic events at the origin of this westward decrease of expansion ages, the estimat…
Genetic structure of Mediterranean populations revealed by Y‐chromosome haplotype analysis
The allelic variability at six Y‐chromosome‐specific polymorphisms (YAP, DYS19, DYS389‐I, DYS390, DYS391, and DYS392) was used to generate male‐specific haplotypes in 333 males representing 12 population samples from the region around the Mediterranean sea. Extreme interindividual variation was observed, as more than 160 distinct Y‐chromosome variants could be defined as six‐locus haplotypes. Concomitant with this high variability, low levels of …
Genetic evidence of an early exit of Homo sapiens sapiens from Africa through eastern Africa
Y-Chromosome Analysis in Egypt Suggests a Genetic Regional Continuity in Northeastern Africa
The geographic location of Egypt, at the interface between North Africa, the Middle East, and southern Europe, prompted us to investigate the genetic diversity of this population and its relationship with neighboring populations. To assess the extent to which the modern Egyptian population reflects this intermediate geographic position, ten Unique Event Polymorphisms (UEPs), mapping to the nonrecombining portion of the Y chromosome, have been typ…
Genetic structure of Mediterranean populations revealed by Y‐chromosome haplotype analysis
The allelic variability at six Y‐chromosome‐specific polymorphisms (YAP, DYS19, DYS389‐I, DYS390, DYS391, and DYS392) was used to generate male‐specific haplotypes in 333 males representing 12 population samples from the region around the Mediterranean sea. Extreme interindividual variation was observed, as more than 160 distinct Y‐chromosome variants could be defined as six‐locus haplotypes. Concomitant with this high variability, low levels of …
Where West Meets East: The Complex mtDNA Landscape of the Southwest and Central Asian Corridor
A population genetics perspective of the Indus Valley through uniparentally-inherited markers
Analysis of mtDNA and Y-chromosome variation in the Indo-Gangetic plains shows that it was a region where genetic components of different geographical origins (from west, east and south) met. The genetic architecture of the populations now living in the area comprise genetic components dating back to different time-periods during the Palaeolithic and the Neolithic. mtDNA data analysis has demonstrated a number of deep-rooting lineages of Pleistoc…
Genetic traces of east‐to‐west human expansion waves in Eurasia
In this study, we describe the landscape of human demographic expansions in Eurasia using a large continental Y chromosome and mitochondrial DNA dataset. Variation at these two uniparentally‐inherited genetic systems retraces expansions that occurred in the past 60 ky, and shows a clear decrease of expansion ages from east to west Eurasia. To investigate the demographic events at the origin of this westward decrease of expansion ages, the estimat…
Lactase Persistence in Central Asia: Phenotype, Genotype, and Evolution
The aim of the present study is to document the evolution of the lactase persistence trait in Central Asia, a geographical area that is thought to have been a region of long-term pastoralism. Several ethnic groups co-exist in this area: Indo-Iranian speakers who are traditionally agriculturist (Tajik) and Turkic speakers who used to be nomadic herders (Kazakh, Karakalpak, Kyrgyz, Turkmen). It was recently demonstrated that horse milking practice …
Génomique humaine et évolution
enseiGnement cours -volution humaine et Gntique des populations et non gntique (i.e., genre, ge, mode de vie) peuvent tre associes des diffrences de rponse l'infection, et comment les variants gntiques associs la variation de l'expression gnique ont t la cible de la slection naturelle. Ce projet nous aidera explorer l'impact de la diversit (pi)gntique sur les variations de rponse immunitaire dans les populations humaines
Génomique humaine et évolution
EnseignementCours – Évolution humaine et génétique des populations (suite)IntroductionDès le début de la génétique moderne, on a distingué quatre facteurs majeurs qui influencent la variabilité génétique : la mutation qui produit de nouveaux types génétiques, la sélection naturelle qui favorise les types génétiques conférant aux individus une meilleure adaptation à l’environnement dans lequel ils évoluent, la dérive génétique qui est l’effet du h…
Génomique humaine et évolution
International audience
Biology (9 works) · Demography (6 works) · Forensic and Genetic Research (6 works) · Geography (6 works) · Population (6 works) · Evolutionary biology (5 works) · Genetics (5 works) · Archaeology (4 works) · Gene (4 works) · Genetics (4 works)