Evropi Τheodoratou
Biographic Data
| ID | 3490941 |
|---|---|
| NAME | Evropi Τheodoratou |
| GIVEN NAMES | Evropi |
| FAMILY NAME | Τheodoratou |
| SIGNATURE | ΤHEODORATOU E |
| AFFILIATIONS | University of Edinburgh |
| ORCID | 0000-0001-5887-9132 |
| VERIFIED | Yes |
| TOTAL WORKS | 23 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 23 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2012 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Folate and global health umbrella review series, part 1
Background: Folate is essential for normal growth and in human health throughout the lifecycle. Clinical deficiency of folate impairs DNA synthesis and results in megaloblastic anaemia, while suboptimal folate status before and in early pregnancy results in an elevated risk of neural tube defects (NTD). The evidence on the association of folate status with other health outcomes is largely fragmented and understudied. We conducted a series of umbr…
Folate and global health umbrella review series, part 2
Background: Folate has been examined extensively in relation to carcinogenesis due to its role in one-carbon metabolism impacting the synthesis of DNA and RNA, methylation processes, and genomic integrity. Current evidence on the relationship between folate status and the risk of cancer is equivocal: low or deficient folate status may contribute to an increased risk of cancers, while high-dose folic acid supplementation may have adverse effects o…
Associations of genetic factors with vascular diabetes complications
Background: To comprehensively assess evidence from published systematic review and meta-analyses (SRMAs) on the genetics of vascular diabetes complications. Methods: A systematic literature search conducted in Medline and Embase identified 63 non-overlapping SRMAs. We re-conducted meta-analyses to compare diabetes with and without complications using multiple genetic models; evaluated associations using Venice criteria and Bayesian false-discove…
National and subnational incidence, mortality and associated factors of colorectal cancer in China
Background: Due to their known variation by geography and economic development, we aimed to evaluate the incidence and mortality of colorectal cancer (CRC) in China over the past decades and identify factors associated with CRC among the Chinese population to provide targeted information on disease prevention. Methods: We conducted a systemic review and meta-analysis of epidemiolocal studies on the incidence, mortality, and associated factors of …
What are the characteristics of participatory surveillance systems for influenza-like-illness
Background: Seasonal influenza causes significant morbidity and mortality, with an estimated 9.4 million hospitalisations and 290 000-650 000 respiratory related-deaths globally each year. Influenza can also cause mild illness, which is why not all symptomatic persons might necessarily be tested for influenza. To monitor influenza activity, healthcare facility-based syndromic surveillance for influenza-like illness is often implemented. Participa…
To what extent is alcohol consumption in social gatherings associated with observance of Covid-19 restrictions? A rapid review
Background: Pre-pandemic research found a connection between alcohol consumption and reduced physical distancing among strangers. Understanding the association between alcohol consumption at social gatherings and observance of COVID-19 restrictions can help inform policy related to the safe operation of public spaces where alcohol is typically consumed, as well as guidance related to the safe conduct of social events in private spaces. Methods: W…
Using evidence, expert opinion and epidemiological model to understand pathways to survival and mortality
BACKGROUND: The reasons why episodes of illness can lead to fatal outcomes in affected persons in low resource settings are numerous and complex. A tool that allows policy makers to better understand those complexities could be useful to improve success of programmes that are implemented globally to reduce mortality. METHODS: We developed a "Pathways to Survival" (PATHS) tool: an epidemiological model using decision trees, available evidence and …
Advances in Covid-19 research until November 2020
Since the declaration of Coronavirus Disease 2019 (COVID-19) pandemic on 11 March 2020 by the WHO, an accumulated number of at least 70 461 926 confirmed cases and 1 599 704 deaths in 216 countries/ territories has been recorded by 14/12/2020 [1]. In line with the established WHO global research roadmap for COVID-19 [2], the UNCOVER (Usher Network for COVID-19 Evidence Reviews) group committed to summarise COVID-19 evidence-based reviews for poli…
Current Covid-19 treatments
BACKGROUND: As SARS-CoV-2 continues to spread worldwide, it has already resulted in over 110 million cases and 2.5 million deaths. Currently, there are no effective COVID-19 treatments, although numerous studies are under way. SARS-CoV-2, however, is not the first coronavirus to cause serious outbreaks. COVID-19 can be compared with previous human coronavirus diseases, such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory S…
Uncover registry
An epidemic of novel Coronavirus Disease 2019 (COVID-19) causing an acute respiratory disease began in December 2019, triggered a Public Health Emergency of International Concern (PHEIC) and was declared a pandemic on 11 March 2020 by the World Health Organisation (WHO). Globally, there has been an accumulated number of 7 823 289 confirmed cases and 431 541 deaths occurred in 216 countries/territories according to the report of WHO of 15 June 202…
The role of children in transmission of Sars-CoV-2
BACKGROUND: Understanding the role of children in the transmission of SARS-CoV-2 is urgently required given its policy implications in relation to the reopening of schools and intergenerational contacts. METHODS: We conducted a rapid review of studies that investigated the role of children in the transmission of SARS-CoV-2. We synthesized evidence for four categories: 1) studies reporting documented cases of SARS-CoV-2 transmission by infected ch…
The role of children in the transmission of Sars-CoV2
Physical activity and Covid-19
Physical activity (PA) is known to be a protective lifestyle factor against several non-communicable diseases while its impact on infectious diseases, including Coronavirus Disease 2019 (COVID-19) is not as clear
National and subnational prevalence and burden of glaucoma in China
BACKGROUND: Glaucoma, the second leading cause of blindness, affects approximately 64.3 million individuals worldwide. In China, demographic ageing is in rapid progress. Yet detailed and up-to-date estimates of the scale of glaucoma are rare. We aimed to quantify and understand the prevalence and burden of glaucoma in China from 1990 to 2015, with projections until 2050. METHODS: For this systematic review and meta-analysis, we searched China Nat…
The national and subnational prevalence and burden of age–related macular degeneration in China
BACKGROUND: Age-related macular degeneration (AMD) is the third most common cause of blindness, and the fourth leading cause of visual impairment worldwide, but little is known about the burden of this disease in the most populous country-China. This study provides the first comprehensive estimates of the prevalence and burden of AMD in China from 1990 to 2015, with projections till 2050. METHODS: In this study, a systematic review and meta-analy…
Causes of death in children younger than five years in China in 2015
BACKGROUND: Substantial progress in reducing the child mortality rate has been made globally in the last two decades. However, for China, the number of children dying from preventable diseases is still very large. It is important to have regularly updated information on the distribution of causes of death (COD) in children to inform policy and research. In this study, we aim to estimate the COD spectrum in children younger than five years old fro…
Barriers to Hospital Deliveries among Ethnic Minority Women with Religious Beliefs in China
This study has highlighted a number of barriers and levers to hospital delivery in rural poor ethnic minority areas which could inform and improve the access and rate of hospital delivery rate; thereby reducing health inequalities in maternal and child health in China
Assembling GHERG
In recent months, the World Health Organization (WHO), independent academic researchers, the Lancet and PLoS Medicine journals worked together to improve reporting of population health estimates. The new guidelines for accurate and transparent health estimates reporting (likely to be named GATHER), which are eagerly awaited, represent a helpful move that should benefit the field of global health metrics. Building on this progress and drawing from…
Global and regional estimates of COPD prevalence
BACKGROUND: The burden of chronic obstructive pulmonary disease (COPD) across many world regions is high. We aim to estimate COPD prevalence and number of disease cases for the years 1990 and 2010 across world regions based on the best available evidence in publicly accessible scientific databases. METHODS: We conducted a systematic search of Medline, EMBASE and Global Health for original, population-based studies providing spirometry-based preva…
Assembling GHERG
apid development of information technologies in the past two decades has brought about major improvements in the generation, sharing and analysis of information on the health status of the entire human population. This has facilitated the development of the field of "Global Health Metrics", which has its champions in World Health Organization's Mortality and Burden of Disease Unit and University of Washington' s Institute for Health Metrics and E…
Optimizing community case management strategies to achieve equitable reduction of childhood pneumonia mortality
BACKGROUND: The aim of this study was to populate the Equitable Impact Sensitive Tool (EQUIST) framework with all necessary data and conduct the first implementation of EQUIST in studying cost-effectiveness of community case management of childhood pneumonia in 5 low- and middle-income countries with relation to equity impact. METHODS: Wealth quintile-specific data were gathered or modelled for all contributory determinants of the EQUIST framewor…
Estimating the incidence of colorectal cancer in Sub–Saharan Africa
Estimating the incidence of colorectal cancer in Sub-Saharan Africa: A systematic analysis Background Nearly two-thirds of annual mortality worldwide is attributable to non-communicable diseases (NCDs), with 70% estimated to occur in low-and middle-income countries (LMIC). Colorectal cancer (CRC) accounts for over 600 000 deaths annually, but data concerning cancer rates in LMIC is very poor. This study analyses the data available to produce an e…
Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza
A cute lower respiratory infections, which broadly include pneumonia and bronchiolitis, are still the leading cause of childhood mortality. ALRI contributed to 18% of all deaths in children younger than five years of age in 2008 [1], and the main pathogens responsible for high mortality were Streptococcus pneumoniae, Haemophilus influenzae and respiratory syncytial virus [2-4]. In addition, meningitis was estimated to contribute up to 200 000 dea…
No prominent works on this page.
Optimizing community case management strategies to achieve equitable reduction of childhood pneumonia mortality
BACKGROUND: The aim of this study was to populate the Equitable Impact Sensitive Tool (EQUIST) framework with all necessary data and conduct the first implementation of EQUIST in studying cost-effectiveness of community case management of childhood pneumonia in 5 low- and middle-income countries with relation to equity impact. METHODS: Wealth quintile-specific data were gathered or modelled for all contributory determinants of the EQUIST framewor…
Estimating the incidence of colorectal cancer in Sub–Saharan Africa
Estimating the incidence of colorectal cancer in Sub-Saharan Africa: A systematic analysis Background Nearly two-thirds of annual mortality worldwide is attributable to non-communicable diseases (NCDs), with 70% estimated to occur in low-and middle-income countries (LMIC). Colorectal cancer (CRC) accounts for over 600 000 deaths annually, but data concerning cancer rates in LMIC is very poor. This study analyses the data available to produce an e…
Setting priorities for development of emerging interventions against childhood pneumonia, meningitis and influenza
A cute lower respiratory infections, which broadly include pneumonia and bronchiolitis, are still the leading cause of childhood mortality. ALRI contributed to 18% of all deaths in children younger than five years of age in 2008 [1], and the main pathogens responsible for high mortality were Streptococcus pneumoniae, Haemophilus influenzae and respiratory syncytial virus [2-4]. In addition, meningitis was estimated to contribute up to 200 000 dea…
Assembling GHERG
In recent months, the World Health Organization (WHO), independent academic researchers, the Lancet and PLoS Medicine journals worked together to improve reporting of population health estimates. The new guidelines for accurate and transparent health estimates reporting (likely to be named GATHER), which are eagerly awaited, represent a helpful move that should benefit the field of global health metrics. Building on this progress and drawing from…
Global and regional estimates of COPD prevalence
BACKGROUND: The burden of chronic obstructive pulmonary disease (COPD) across many world regions is high. We aim to estimate COPD prevalence and number of disease cases for the years 1990 and 2010 across world regions based on the best available evidence in publicly accessible scientific databases. METHODS: We conducted a systematic search of Medline, EMBASE and Global Health for original, population-based studies providing spirometry-based preva…
Assembling GHERG
apid development of information technologies in the past two decades has brought about major improvements in the generation, sharing and analysis of information on the health status of the entire human population. This has facilitated the development of the field of "Global Health Metrics", which has its champions in World Health Organization's Mortality and Burden of Disease Unit and University of Washington' s Institute for Health Metrics and E…
Causes of death in children younger than five years in China in 2015
BACKGROUND: Substantial progress in reducing the child mortality rate has been made globally in the last two decades. However, for China, the number of children dying from preventable diseases is still very large. It is important to have regularly updated information on the distribution of causes of death (COD) in children to inform policy and research. In this study, we aim to estimate the COD spectrum in children younger than five years old fro…
Barriers to Hospital Deliveries among Ethnic Minority Women with Religious Beliefs in China
This study has highlighted a number of barriers and levers to hospital delivery in rural poor ethnic minority areas which could inform and improve the access and rate of hospital delivery rate; thereby reducing health inequalities in maternal and child health in China
National and subnational prevalence and burden of glaucoma in China
BACKGROUND: Glaucoma, the second leading cause of blindness, affects approximately 64.3 million individuals worldwide. In China, demographic ageing is in rapid progress. Yet detailed and up-to-date estimates of the scale of glaucoma are rare. We aimed to quantify and understand the prevalence and burden of glaucoma in China from 1990 to 2015, with projections until 2050. METHODS: For this systematic review and meta-analysis, we searched China Nat…
The national and subnational prevalence and burden of age–related macular degeneration in China
BACKGROUND: Age-related macular degeneration (AMD) is the third most common cause of blindness, and the fourth leading cause of visual impairment worldwide, but little is known about the burden of this disease in the most populous country-China. This study provides the first comprehensive estimates of the prevalence and burden of AMD in China from 1990 to 2015, with projections till 2050. METHODS: In this study, a systematic review and meta-analy…
Uncover registry
An epidemic of novel Coronavirus Disease 2019 (COVID-19) causing an acute respiratory disease began in December 2019, triggered a Public Health Emergency of International Concern (PHEIC) and was declared a pandemic on 11 March 2020 by the World Health Organisation (WHO). Globally, there has been an accumulated number of 7 823 289 confirmed cases and 431 541 deaths occurred in 216 countries/territories according to the report of WHO of 15 June 202…
The role of children in transmission of Sars-CoV-2
BACKGROUND: Understanding the role of children in the transmission of SARS-CoV-2 is urgently required given its policy implications in relation to the reopening of schools and intergenerational contacts. METHODS: We conducted a rapid review of studies that investigated the role of children in the transmission of SARS-CoV-2. We synthesized evidence for four categories: 1) studies reporting documented cases of SARS-CoV-2 transmission by infected ch…
The role of children in the transmission of Sars-CoV2
Physical activity and Covid-19
Physical activity (PA) is known to be a protective lifestyle factor against several non-communicable diseases while its impact on infectious diseases, including Coronavirus Disease 2019 (COVID-19) is not as clear
Using evidence, expert opinion and epidemiological model to understand pathways to survival and mortality
BACKGROUND: The reasons why episodes of illness can lead to fatal outcomes in affected persons in low resource settings are numerous and complex. A tool that allows policy makers to better understand those complexities could be useful to improve success of programmes that are implemented globally to reduce mortality. METHODS: We developed a "Pathways to Survival" (PATHS) tool: an epidemiological model using decision trees, available evidence and …
Advances in Covid-19 research until November 2020
Since the declaration of Coronavirus Disease 2019 (COVID-19) pandemic on 11 March 2020 by the WHO, an accumulated number of at least 70 461 926 confirmed cases and 1 599 704 deaths in 216 countries/ territories has been recorded by 14/12/2020 [1]. In line with the established WHO global research roadmap for COVID-19 [2], the UNCOVER (Usher Network for COVID-19 Evidence Reviews) group committed to summarise COVID-19 evidence-based reviews for poli…
Current Covid-19 treatments
BACKGROUND: As SARS-CoV-2 continues to spread worldwide, it has already resulted in over 110 million cases and 2.5 million deaths. Currently, there are no effective COVID-19 treatments, although numerous studies are under way. SARS-CoV-2, however, is not the first coronavirus to cause serious outbreaks. COVID-19 can be compared with previous human coronavirus diseases, such as Severe Acute Respiratory Syndrome (SARS) and Middle East Respiratory S…
To what extent is alcohol consumption in social gatherings associated with observance of Covid-19 restrictions? A rapid review
Background: Pre-pandemic research found a connection between alcohol consumption and reduced physical distancing among strangers. Understanding the association between alcohol consumption at social gatherings and observance of COVID-19 restrictions can help inform policy related to the safe operation of public spaces where alcohol is typically consumed, as well as guidance related to the safe conduct of social events in private spaces. Methods: W…
National and subnational incidence, mortality and associated factors of colorectal cancer in China
Background: Due to their known variation by geography and economic development, we aimed to evaluate the incidence and mortality of colorectal cancer (CRC) in China over the past decades and identify factors associated with CRC among the Chinese population to provide targeted information on disease prevention. Methods: We conducted a systemic review and meta-analysis of epidemiolocal studies on the incidence, mortality, and associated factors of …
What are the characteristics of participatory surveillance systems for influenza-like-illness
Background: Seasonal influenza causes significant morbidity and mortality, with an estimated 9.4 million hospitalisations and 290 000-650 000 respiratory related-deaths globally each year. Influenza can also cause mild illness, which is why not all symptomatic persons might necessarily be tested for influenza. To monitor influenza activity, healthcare facility-based syndromic surveillance for influenza-like illness is often implemented. Participa…
Associations of genetic factors with vascular diabetes complications
Background: To comprehensively assess evidence from published systematic review and meta-analyses (SRMAs) on the genetics of vascular diabetes complications. Methods: A systematic literature search conducted in Medline and Embase identified 63 non-overlapping SRMAs. We re-conducted meta-analyses to compare diabetes with and without complications using multiple genetic models; evaluated associations using Venice criteria and Bayesian false-discove…
Folate and global health umbrella review series, part 1
Background: Folate is essential for normal growth and in human health throughout the lifecycle. Clinical deficiency of folate impairs DNA synthesis and results in megaloblastic anaemia, while suboptimal folate status before and in early pregnancy results in an elevated risk of neural tube defects (NTD). The evidence on the association of folate status with other health outcomes is largely fragmented and understudied. We conducted a series of umbr…
Folate and global health umbrella review series, part 2
Background: Folate has been examined extensively in relation to carcinogenesis due to its role in one-carbon metabolism impacting the synthesis of DNA and RNA, methylation processes, and genomic integrity. Current evidence on the relationship between folate status and the risk of cancer is equivocal: low or deficient folate status may contribute to an increased risk of cancers, while high-dose folic acid supplementation may have adverse effects o…
Medicine (21 works) · MEDLINE (15 works) · Internal Medicine (12 works) · Environmental health (11 works) · Population (8 works) · Biology (7 works) · Demography (7 works) · Computer Science (6 works) · Geography (6 works) · Virology (6 works)