Qiongshi Lu
Biographic Data
| ID | 3581253 |
|---|---|
| NAME | Qiongshi Lu |
| GIVEN NAMES | Qiongshi |
| FAMILY NAME | Lu |
| SIGNATURE | LU Q |
| AFFILIATIONS | University of Wisconsin–Madison |
| ORCID | 0000-0002-4514-0969 |
| VERIFIED | Yes |
| TOTAL WORKS | 12 |
| TOTAL CITATIONS | 25 |
| AUTHOR COUNT | 12 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2021 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 2 |
Associations between common genetic variants and income provide insights about the socio-economic health gradient
We conducted a genome-wide association study on income among individuals of European descent ( N = 668,288) to investigate the relationship between socio-economic status and health disparities. We identified 162 genomic loci associated with a common genetic factor underlying various income measures, all with small effect sizes (the Income Factor). Our polygenic index captures 1–5% of income variance, with only one fourth due to direct genetic eff…
Pigeon: A Statistical Framework for Estimating Gene-Environment Interaction for Polygenic Traits
Separating Scarring Effect and Selection of Early-Life Exposures With Genetic Data
Causal life course research examining consequences of early-life exposures has largely relied on associations between early-life environments and later-life outcomes using exogenous environmental shocks. Nonetheless, even with (quasi-)randomized early-life exposures, these associations may reflect not only causation (“scarring”) but also selection (i.e., which members are included in data assessing later life). Investigating this selection and it…
Analysis of Sex-Specific Gene-by-Cohort and Genetic Correlation-by-Cohort Interaction in Educational and Reproductive Outcomes Using the UK Biobank Data
Synthesizing prior gene-by-cohort (G×C) interaction studies, we theorize that changes in genetic effects by social conditions depend on the level of resource constraints, the distribution and use of resources, structural constraints, and constraints on individual choice. Motivated by the theory, we explored several sex-specific G×C trends across a set of outcomes using 30 birth cohorts of UK Biobank data (N = 400,000). We find that genetic coeffi…
Re-examining the relationship between education and adult mental health in the UK: A research note
Previous studies using variation in education arising from compulsory schooling laws have found no causal effects of education on mental health in the UK. We re-examine the relationship between education and mental health in the UK by taking a different approach: sibling fixed-effects with controls for polygenic scores (summary measures of genetic predisposition) for educational attainment and adult depressive symptoms. We find that higher educat…
The Big (Genetic) Sort? A Research Note on Migration Patterns and Their Genetic Imprint in the United Kingdom
This research note reinvestigates Abdellaoui et al.’s (2019) findings that genetically selective migration may lead to persistent and accumulating socioeconomic and health inequalities between types (coal mining or non–coal mining) of places in the United Kingdom. Their migration measure classified migrants who moved to the same type of place (coal mining to coal mining or non–coal mining to non–coal mining) into “stay” categories, preventing the…
Understanding Internal Migration: A Research Note Providing an Assessment of Migration Selection With Genetic Data
Migration is selective, resulting in inequalities between migrants and nonmigrants. However, investigating migration selection is empirically challenging because combined pre- and post-migration data are rarely available. We propose an alternative approach to assessing internal migration selection by integrating genetic data, enabling an investigation of migration selection with cross-sectional data collected post-migration. Using data from the U…
Gender differences in the association between parity and cognitive function: Evidence from the UK biobank
Detecting genetic heterogeneities in response to trauma: The case of 9/11
The current study evaluates genetic heterogeneities in response to trauma among U.S. young adults. Using Add Health Wave III, which coincidently overlapped with the September 11 attacks, and a depression mean and variance polygenic scores, we investigate how the polygenic scores moderate the causal effect of 9/11 on mental health. Our results show the presence of genetic heterogeneity, where those with high genetic plasticity experience an increa…
Higher educational attainment is associated with longer telomeres in midlife: Evidence from sibling comparisons in the UK Biobank
Prior studies have established that higher educational attainment is associated with a longer telomere length (TL), a marker of cellular aging. However, it is unclear whether extant associations are causal, since they are likely confounded by unobserved genetic, early-life and family background factors that are correlated with education and TL. We leverage sibling differences in TL, education and measured genetics (polygenic scores for educationa…
Gene-by-peer-environment interaction effects on cigarette, alcohol, and marijuana use among US high school students of European Ancestry
The effects of education on cognition in older age: Evidence from genotyped Siblings
The effects of education on cognition in older age: Evidence from genotyped Siblings
Gender differences in the association between parity and cognitive function: Evidence from the UK biobank
Associations between common genetic variants and income provide insights about the socio-economic health gradient
We conducted a genome-wide association study on income among individuals of European descent ( N = 668,288) to investigate the relationship between socio-economic status and health disparities. We identified 162 genomic loci associated with a common genetic factor underlying various income measures, all with small effect sizes (the Income Factor). Our polygenic index captures 1–5% of income variance, with only one fourth due to direct genetic eff…
The Big (Genetic) Sort? A Research Note on Migration Patterns and Their Genetic Imprint in the United Kingdom
This research note reinvestigates Abdellaoui et al.’s (2019) findings that genetically selective migration may lead to persistent and accumulating socioeconomic and health inequalities between types (coal mining or non–coal mining) of places in the United Kingdom. Their migration measure classified migrants who moved to the same type of place (coal mining to coal mining or non–coal mining to non–coal mining) into “stay” categories, preventing the…
Understanding Internal Migration: A Research Note Providing an Assessment of Migration Selection With Genetic Data
Migration is selective, resulting in inequalities between migrants and nonmigrants. However, investigating migration selection is empirically challenging because combined pre- and post-migration data are rarely available. We propose an alternative approach to assessing internal migration selection by integrating genetic data, enabling an investigation of migration selection with cross-sectional data collected post-migration. Using data from the U…
Gene-by-peer-environment interaction effects on cigarette, alcohol, and marijuana use among US high school students of European Ancestry
The effects of education on cognition in older age: Evidence from genotyped Siblings
Detecting genetic heterogeneities in response to trauma: The case of 9/11
The current study evaluates genetic heterogeneities in response to trauma among U.S. young adults. Using Add Health Wave III, which coincidently overlapped with the September 11 attacks, and a depression mean and variance polygenic scores, we investigate how the polygenic scores moderate the causal effect of 9/11 on mental health. Our results show the presence of genetic heterogeneity, where those with high genetic plasticity experience an increa…
Higher educational attainment is associated with longer telomeres in midlife: Evidence from sibling comparisons in the UK Biobank
Prior studies have established that higher educational attainment is associated with a longer telomere length (TL), a marker of cellular aging. However, it is unclear whether extant associations are causal, since they are likely confounded by unobserved genetic, early-life and family background factors that are correlated with education and TL. We leverage sibling differences in TL, education and measured genetics (polygenic scores for educationa…
Gene-by-peer-environment interaction effects on cigarette, alcohol, and marijuana use among US high school students of European Ancestry
Re-examining the relationship between education and adult mental health in the UK: A research note
Previous studies using variation in education arising from compulsory schooling laws have found no causal effects of education on mental health in the UK. We re-examine the relationship between education and mental health in the UK by taking a different approach: sibling fixed-effects with controls for polygenic scores (summary measures of genetic predisposition) for educational attainment and adult depressive symptoms. We find that higher educat…
The Big (Genetic) Sort? A Research Note on Migration Patterns and Their Genetic Imprint in the United Kingdom
This research note reinvestigates Abdellaoui et al.’s (2019) findings that genetically selective migration may lead to persistent and accumulating socioeconomic and health inequalities between types (coal mining or non–coal mining) of places in the United Kingdom. Their migration measure classified migrants who moved to the same type of place (coal mining to coal mining or non–coal mining to non–coal mining) into “stay” categories, preventing the…
Understanding Internal Migration: A Research Note Providing an Assessment of Migration Selection With Genetic Data
Migration is selective, resulting in inequalities between migrants and nonmigrants. However, investigating migration selection is empirically challenging because combined pre- and post-migration data are rarely available. We propose an alternative approach to assessing internal migration selection by integrating genetic data, enabling an investigation of migration selection with cross-sectional data collected post-migration. Using data from the U…
Gender differences in the association between parity and cognitive function: Evidence from the UK biobank
Separating Scarring Effect and Selection of Early-Life Exposures With Genetic Data
Causal life course research examining consequences of early-life exposures has largely relied on associations between early-life environments and later-life outcomes using exogenous environmental shocks. Nonetheless, even with (quasi-)randomized early-life exposures, these associations may reflect not only causation (“scarring”) but also selection (i.e., which members are included in data assessing later life). Investigating this selection and it…
Analysis of Sex-Specific Gene-by-Cohort and Genetic Correlation-by-Cohort Interaction in Educational and Reproductive Outcomes Using the UK Biobank Data
Synthesizing prior gene-by-cohort (G×C) interaction studies, we theorize that changes in genetic effects by social conditions depend on the level of resource constraints, the distribution and use of resources, structural constraints, and constraints on individual choice. Motivated by the theory, we explored several sex-specific G×C trends across a set of outcomes using 30 birth cohorts of UK Biobank data (N = 400,000). We find that genetic coeffi…
Associations between common genetic variants and income provide insights about the socio-economic health gradient
We conducted a genome-wide association study on income among individuals of European descent ( N = 668,288) to investigate the relationship between socio-economic status and health disparities. We identified 162 genomic loci associated with a common genetic factor underlying various income measures, all with small effect sizes (the Income Factor). Our polygenic index captures 1–5% of income variance, with only one fourth due to direct genetic eff…
Pigeon: A Statistical Framework for Estimating Gene-Environment Interaction for Polygenic Traits
Biology (7 works) · Medicine (7 works) · Psychology (7 works) · Demography (6 works) · Genetics (6 works) · Sociology (6 works) · Biobank (5 works) · Birth, Development, and Health (5 works) · Developmental psychology (5 works) · Genetic Associations and Epidemiology (5 works)