Lei Hu
Biographic Data
| ID | 3702074 |
|---|---|
| NAME | Lei Hu |
| GIVEN NAMES | Lei |
| FAMILY NAME | Hu |
| SIGNATURE | HU L |
| AFFILIATIONS | Central South University |
| ORCID | 0000-0001-9268-4697 |
| VERIFIED | Yes |
| TOTAL WORKS | 22 |
| TOTAL CITATIONS | 5 |
| AUTHOR COUNT | 22 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2014 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
Alaskan regional-scale measurements show late season ecosystem carbonyl sulfide uptake decoupled from gross photosynthesis
Increasing atmospheric CO 2 seasonal cycle amplitudes in boreal regions have been attributed to climate-driven changes in land ecosystems, but terrestrial biosphere models (TBMs) are unable to replicate observations, leading to large uncertainties in future predictions of carbon cycle changes. Accurately partitioning net ecosystem exchange into its component fluxes—gross primary production (GPP) and respiration—is essential for understanding impa…
Environmental performance and urban land competitiveness: Insights from mega sport event bidding outcomes
Association between air pollution and risk of non-alcoholic fatty liver disease: An updated meta-analysis
Objective: Air pollution is a major environmental risk to human health, with increasing evidence linking it to non-alcoholic fatty liver disease (NAFLD). However, findings remain inconsistent. This meta-analysis aimed to assess the relationship between air pollutants and the risk of NAFLD. Methods PubMed, Embase, and Web of Science were systematically searched for studies published up to March 20, 2025. A random effects model was used to estimate…
Integrative pharmacological analysis of modified Zuojin formula: Inhibiting the HIF-1α-mediated glycolytic pathway in chronic atrophic gastritis
Spatial complex correlation characteristics of carbon emissions and carbon transboundary transfer: Assessment of the carbon footprint in four mega-urban agglomerations in China
Urban agglomerations, as the main carriers of, serve as critical platforms for emission reduction and carbon absorption playing a pivotal role in achieving the goals of ''carbon peaking'' and ''carbon neutrality'' targets. This study investigates these issues from the dual perspectives of ''carbon sources'' and ''carbon sinks,'' utilizing a modified gravity model to construct a spatial correlation matrix of carbon footprint pressure. Based on thi…
Psychometric properties of the Chinese version of Nightmare Distress Questionnaire in adolescents with psychiatric disorders
Escalating rainstorm-induced flood risks in the Yellow River Basin, China
The warming climate-induced intensification of hydrological cycle is amplifying extreme precipitation and increasing flood risk at regional and global scales. The evaluation of flood risk, which depends on assessment indicators, weights, as well as data quality, is the first step toward mitigation flood disasters. In this study, we accepted ten risk assessment indicators concerning hazard of disaster-causing factors, sensitivity of hazard-forming…
Immersed in the Fleeting World of Modernity: Edo Music and the Aestheticism of Melancholy in Nagai Kafū’s Literary World
Distinct responses of soil bacterial communities to N and P fertilization in a Tibetan alpine meadow of China
Increased nitrogen (N) and phosphorus (P) availability, due to fertilization and deposition, is expected to influence soil microbial community structure and function. However, little is known about the sensitivity and dependency of soil microbial structure on the levels of N and P, and on the integration of N and P inputs in alpine meadow ecosystems. Here, we implemented a 3‐year manipulative fertilization study with four levels (0, 10, 20, and 3…
The action logic of the older adults about health-seeking in South Rural China
This study showed that the medical practices of the rural elderly were profoundly influenced by their perceptions of health and their life experiences. In the face of diseases, they tended to keep their lives in order, preferring self-treatment practices that address symptoms or selectively following medical advice rather than medical and science-based clinical solutions. In the future, the construction of rural health care should focus on changi…
To leave or stay? Out‐migration of skilled migrants in Beijing, China
The out‐migration decision of skilled migrants in first‐tier cities is receiving growing attention from researchers and policymakers in recent years. We conducted a survey on skilled people in Beijing who did not have a household registration ( hukou ). We employed a Probit model with selection to determine the individual socioeconomic characteristics compelling skilled migrants to remigrate from first‐tier cities to other regions. The analysis r…
Geospatial Semantics Analysis of the Qinghai–Tibetan Plateau Based on Microblog Short Texts
Place descriptions record qualitative information related to places and their spatial relationships; thus, the geospatial semantics of a place can be extracted from place descriptions. In this study, geotagged microblog short texts recorded in 2017 from the Tibetan Autonomous Region and Qinghai Province were used to extract the place semantics of the Qinghai–Tibetan Plateau (QTP). ERNIE, a language representation model enhanced by knowledge, was …
Influential Factor Detection for Tourism on the Qinghai-Tibet Plateau Based on Social Media Data
Tourism is playing an important role in the economic development of the Qinghai-Tibet Plateau (QTP). To better develop tourism in this region, the spatial heterogeneity of influencing factors on tourism needs to be studied. Using the spatial distribution of tourism potential from social media data, this paper analyzes the influencing factors of tourism on the QTP from the perspective of spatial heterogeneity. We extract microblogs related to trav…
The Integration of Linguistic and Geospatial Features Using Global Context Embedding for Automated Text Geocoding
Geocoding is an essential procedure in geographical information retrieval to associate place names with coordinates. Due to the inherent ambiguity of place names in natural language and the scarcity of place names in textual data, it is widely recognized that geocoding is challenging. Recent advances in deep learning have promoted the use of the neural network to improve the performance of geocoding. However, most of the existing approaches consi…
Root dynamics along a restoration chronosequence of revegetated grasslands in degraded alpine meadows of the Qinghai‐Tibetan Plateau, China
Revegetation using perennial grass, such as Elymus nutans is an effective approach in abating grassland degradation on the Qinghai‐Tibetan Plateau. However, knowledge of root dynamics along restoration chronosequences of revegetated grasslands are limited. To gain better insight into root dynamics, we used minirhizotrons to examine changes in root traits, including root standing crop, production, mortality, and turnover along a restoration chrono…
Evidence for an Interaction Between Nedd4 and Childhood Trauma on Clinical Characters of Schizophrenia With Family History of Psychosis
Background: Neural precursor cell-expressed developmentally downregulated 4 ( NEDD4 ) polymorphisms and childhood trauma (CT) are associated with schizophrenia. However, whether NEDD4 interacts with CT on symptoms of schizophrenia remains unknown. This study aimed to investigate the gene-environment interaction effect. Methods: We recruited 289 schizophrenia patients and 487 controls and genotyped rs2303579, rs3088077, rs7162435, rs11550869, and …
Prevalence and associated factors of metabolic syndrome in adults: A population-based epidemiological survey in Jiangxi province, China
To the best of our knowledge, this was the latest study on MS prevalence in Jiangxi province. In conclusion, MS prevalence is high in Jiangxi province. Considering the unhealthy lifestyle, education is urgently needed to prevent the rapid increase of MS prevalence
Overexpression of Rack1 Promotes Metastasis by Enhancing Epithelial-Mesenchymal Transition and Predicts Poor Prognosis in Human Glioma
Emerging studies show that dysregulation of the receptor of activated protein kinase C1 (RACK1) plays a crucial role in tumorigenesis and progression of various cancers. However, the biological function and underlying mechanism of RACK1 in glioma remains poorly defined. Here, we found that RACK1 was significantly up-regulated in glioma tissues compared with normal brain tissues, being closely related to clinical stage of glioma both in mRNA and p…
Up-Regulation of Long Non-Coding RNA AB073614 Predicts a Poor Prognosis in Patients with Glioma
Dysregulated long noncoding RNAs (lncRNAs) have been found in human diseases, especially in cancer. Emerging evidence indicates that dysregulated lncRNAs are implicated in tumorigenesis and cancer progression. LncRNA AB073614 characterized as a new candidate lncRNA promotes the development of ovarian cancer. However, the role of lncRNA AB073614 in human gliomas remains unknown. The expression of AB073614 was detected in 65 glioma tissues and 13 n…
In Vitro and in Vivo Inhibitory Effects of Glycyrrhetinic Acid in Mice and Human Cytochrome P450 3A4
Glycyrrhetinic acid (GA) has been used clinically in the treatment of patients with chronic hepatitis. This study evaluated the effect of GA on the activity of five P450(CYP450) cytochrome enzymes: CYP2A6, CYP2C9, CYP2C19, CYP2D6, and CYP3A4, in human liver microsomes (HLMs) and recombinant cDNA-expressed enzyme systems using a HPLC-MS/MS CYP-specific probe substrate assay. With midazolam as the probe substrate, GA greatly decreased CYP3A4 activi…
Mechanism-based inhibition of Alantolactone on human cytochrome P450 3A4 in vitro and activity of hepatic cytochrome P450 in mice
Dose-response of oridonin on hepatic cytochromes P450 mRNA expression and activities in mice
To leave or stay? Out‐migration of skilled migrants in Beijing, China
The out‐migration decision of skilled migrants in first‐tier cities is receiving growing attention from researchers and policymakers in recent years. We conducted a survey on skilled people in Beijing who did not have a household registration ( hukou ). We employed a Probit model with selection to determine the individual socioeconomic characteristics compelling skilled migrants to remigrate from first‐tier cities to other regions. The analysis r…
Spatial complex correlation characteristics of carbon emissions and carbon transboundary transfer: Assessment of the carbon footprint in four mega-urban agglomerations in China
Urban agglomerations, as the main carriers of, serve as critical platforms for emission reduction and carbon absorption playing a pivotal role in achieving the goals of ''carbon peaking'' and ''carbon neutrality'' targets. This study investigates these issues from the dual perspectives of ''carbon sources'' and ''carbon sinks,'' utilizing a modified gravity model to construct a spatial correlation matrix of carbon footprint pressure. Based on thi…
Dose-response of oridonin on hepatic cytochromes P450 mRNA expression and activities in mice
In Vitro and in Vivo Inhibitory Effects of Glycyrrhetinic Acid in Mice and Human Cytochrome P450 3A4
Glycyrrhetinic acid (GA) has been used clinically in the treatment of patients with chronic hepatitis. This study evaluated the effect of GA on the activity of five P450(CYP450) cytochrome enzymes: CYP2A6, CYP2C9, CYP2C19, CYP2D6, and CYP3A4, in human liver microsomes (HLMs) and recombinant cDNA-expressed enzyme systems using a HPLC-MS/MS CYP-specific probe substrate assay. With midazolam as the probe substrate, GA greatly decreased CYP3A4 activi…
Mechanism-based inhibition of Alantolactone on human cytochrome P450 3A4 in vitro and activity of hepatic cytochrome P450 in mice
Overexpression of Rack1 Promotes Metastasis by Enhancing Epithelial-Mesenchymal Transition and Predicts Poor Prognosis in Human Glioma
Emerging studies show that dysregulation of the receptor of activated protein kinase C1 (RACK1) plays a crucial role in tumorigenesis and progression of various cancers. However, the biological function and underlying mechanism of RACK1 in glioma remains poorly defined. Here, we found that RACK1 was significantly up-regulated in glioma tissues compared with normal brain tissues, being closely related to clinical stage of glioma both in mRNA and p…
Up-Regulation of Long Non-Coding RNA AB073614 Predicts a Poor Prognosis in Patients with Glioma
Dysregulated long noncoding RNAs (lncRNAs) have been found in human diseases, especially in cancer. Emerging evidence indicates that dysregulated lncRNAs are implicated in tumorigenesis and cancer progression. LncRNA AB073614 characterized as a new candidate lncRNA promotes the development of ovarian cancer. However, the role of lncRNA AB073614 in human gliomas remains unknown. The expression of AB073614 was detected in 65 glioma tissues and 13 n…
Prevalence and associated factors of metabolic syndrome in adults: A population-based epidemiological survey in Jiangxi province, China
To the best of our knowledge, this was the latest study on MS prevalence in Jiangxi province. In conclusion, MS prevalence is high in Jiangxi province. Considering the unhealthy lifestyle, education is urgently needed to prevent the rapid increase of MS prevalence
Geospatial Semantics Analysis of the Qinghai–Tibetan Plateau Based on Microblog Short Texts
Place descriptions record qualitative information related to places and their spatial relationships; thus, the geospatial semantics of a place can be extracted from place descriptions. In this study, geotagged microblog short texts recorded in 2017 from the Tibetan Autonomous Region and Qinghai Province were used to extract the place semantics of the Qinghai–Tibetan Plateau (QTP). ERNIE, a language representation model enhanced by knowledge, was …
Influential Factor Detection for Tourism on the Qinghai-Tibet Plateau Based on Social Media Data
Tourism is playing an important role in the economic development of the Qinghai-Tibet Plateau (QTP). To better develop tourism in this region, the spatial heterogeneity of influencing factors on tourism needs to be studied. Using the spatial distribution of tourism potential from social media data, this paper analyzes the influencing factors of tourism on the QTP from the perspective of spatial heterogeneity. We extract microblogs related to trav…
The Integration of Linguistic and Geospatial Features Using Global Context Embedding for Automated Text Geocoding
Geocoding is an essential procedure in geographical information retrieval to associate place names with coordinates. Due to the inherent ambiguity of place names in natural language and the scarcity of place names in textual data, it is widely recognized that geocoding is challenging. Recent advances in deep learning have promoted the use of the neural network to improve the performance of geocoding. However, most of the existing approaches consi…
Root dynamics along a restoration chronosequence of revegetated grasslands in degraded alpine meadows of the Qinghai‐Tibetan Plateau, China
Revegetation using perennial grass, such as Elymus nutans is an effective approach in abating grassland degradation on the Qinghai‐Tibetan Plateau. However, knowledge of root dynamics along restoration chronosequences of revegetated grasslands are limited. To gain better insight into root dynamics, we used minirhizotrons to examine changes in root traits, including root standing crop, production, mortality, and turnover along a restoration chrono…
Evidence for an Interaction Between Nedd4 and Childhood Trauma on Clinical Characters of Schizophrenia With Family History of Psychosis
Background: Neural precursor cell-expressed developmentally downregulated 4 ( NEDD4 ) polymorphisms and childhood trauma (CT) are associated with schizophrenia. However, whether NEDD4 interacts with CT on symptoms of schizophrenia remains unknown. This study aimed to investigate the gene-environment interaction effect. Methods: We recruited 289 schizophrenia patients and 487 controls and genotyped rs2303579, rs3088077, rs7162435, rs11550869, and …
To leave or stay? Out‐migration of skilled migrants in Beijing, China
The out‐migration decision of skilled migrants in first‐tier cities is receiving growing attention from researchers and policymakers in recent years. We conducted a survey on skilled people in Beijing who did not have a household registration ( hukou ). We employed a Probit model with selection to determine the individual socioeconomic characteristics compelling skilled migrants to remigrate from first‐tier cities to other regions. The analysis r…
Immersed in the Fleeting World of Modernity: Edo Music and the Aestheticism of Melancholy in Nagai Kafū’s Literary World
Distinct responses of soil bacterial communities to N and P fertilization in a Tibetan alpine meadow of China
Increased nitrogen (N) and phosphorus (P) availability, due to fertilization and deposition, is expected to influence soil microbial community structure and function. However, little is known about the sensitivity and dependency of soil microbial structure on the levels of N and P, and on the integration of N and P inputs in alpine meadow ecosystems. Here, we implemented a 3‐year manipulative fertilization study with four levels (0, 10, 20, and 3…
The action logic of the older adults about health-seeking in South Rural China
This study showed that the medical practices of the rural elderly were profoundly influenced by their perceptions of health and their life experiences. In the face of diseases, they tended to keep their lives in order, preferring self-treatment practices that address symptoms or selectively following medical advice rather than medical and science-based clinical solutions. In the future, the construction of rural health care should focus on changi…
Escalating rainstorm-induced flood risks in the Yellow River Basin, China
The warming climate-induced intensification of hydrological cycle is amplifying extreme precipitation and increasing flood risk at regional and global scales. The evaluation of flood risk, which depends on assessment indicators, weights, as well as data quality, is the first step toward mitigation flood disasters. In this study, we accepted ten risk assessment indicators concerning hazard of disaster-causing factors, sensitivity of hazard-forming…
Association between air pollution and risk of non-alcoholic fatty liver disease: An updated meta-analysis
Objective: Air pollution is a major environmental risk to human health, with increasing evidence linking it to non-alcoholic fatty liver disease (NAFLD). However, findings remain inconsistent. This meta-analysis aimed to assess the relationship between air pollutants and the risk of NAFLD. Methods PubMed, Embase, and Web of Science were systematically searched for studies published up to March 20, 2025. A random effects model was used to estimate…
Integrative pharmacological analysis of modified Zuojin formula: Inhibiting the HIF-1α-mediated glycolytic pathway in chronic atrophic gastritis
Spatial complex correlation characteristics of carbon emissions and carbon transboundary transfer: Assessment of the carbon footprint in four mega-urban agglomerations in China
Urban agglomerations, as the main carriers of, serve as critical platforms for emission reduction and carbon absorption playing a pivotal role in achieving the goals of ''carbon peaking'' and ''carbon neutrality'' targets. This study investigates these issues from the dual perspectives of ''carbon sources'' and ''carbon sinks,'' utilizing a modified gravity model to construct a spatial correlation matrix of carbon footprint pressure. Based on thi…
Psychometric properties of the Chinese version of Nightmare Distress Questionnaire in adolescents with psychiatric disorders
Alaskan regional-scale measurements show late season ecosystem carbonyl sulfide uptake decoupled from gross photosynthesis
Increasing atmospheric CO 2 seasonal cycle amplitudes in boreal regions have been attributed to climate-driven changes in land ecosystems, but terrestrial biosphere models (TBMs) are unable to replicate observations, leading to large uncertainties in future predictions of carbon cycle changes. Accurately partitioning net ecosystem exchange into its component fluxes—gross primary production (GPP) and respiration—is essential for understanding impa…
Environmental performance and urban land competitiveness: Insights from mega sport event bidding outcomes
Biology (8 works) · Geography (7 works) · China (6 works) · Medicine (6 works) · Internal Medicine (5 works) · Chemistry (4 works) · Computer Science (4 works) · Gene (4 works) · Pharmacology (4 works) · Biochemistry (3 works)