Nathan D Sepeda

Biographic Data

ID3824475
NAMENathan D Sepeda
GIVEN NAMESNathan D
FAMILY NAMESepeda
SIGNATURESEPEDA N D
AFFILIATIONSJohns Hopkins University
VERIFIEDNo
TOTAL WORKS11
TOTAL CITATIONS1
AUTHOR COUNT11
EDITOR COUNT0
FIRST PUBLICATION YEAR2020
LATEST PUBLICATION YEAR2026
H-INDEX1

  • Mystical dynamics

    Open AccessKurt Stocker, Matthias Hartmann et al.ARTICLEReligion Brain & Behavior2026

  • Patterns of Internalizing Problems, Substance Use and Cognitive Flexibility Before and After Naturalistic Psilocybin Use

    Open AccessJérémie Richard, Jeremy Scott et al.ARTICLEInternational Journal of Mental…2025

  • Shame, Guilt and Psychedelic Experience

    David S Mathai, Daniel E Roberts et al.ARTICLEJournal of Psychoactive Drugs2025

    The classic psychedelic psilocybin has attracted special interest across clinical and non-clinical settings as a potential tool for mental health. Despite increasing attention to challenging psychedelic experiences, few studies have explored the relevance of shame-related processes with psychedelic use. This prospective, longitudinal study involved sequential, automated, web-based surveys that collected data from 679 adults planning to use psiloc…

  • Reactivations Associated with the Use of 5-MeO-DMT Among Spanish-Speaking Individuals

    Ana María Ortiz Bernal, Charles L Raison et al.ARTICLEJournal of Psychoactive Drugs2025

    5-Methoxy- N,N -dimethyltryptamine (5-MeO-DMT) is a psychedelic gaining interest as a potential mental health treatment. However, a poorly characterized phenomenon termed reactivation (similar to "flashbacks") is commonly reported with 5-MeO-DMT use and merits investigation. This study examined the prevalence, predictors, and emotional valence of reactivations among Spanish-speaking individuals. Specifically, we investigated whether gender, time …

  • Five-year outcomes of psilocybin-assisted therapy for Major Depressive Disorder

    Open AccessA K Davis, Meghan A Dellacrosse et al.ARTICLEJournal of Psychedelic Studies2025References: 49

    BackgroundMajor Depressive Disorder (MDD) is a leading cause of disability and economic loss, with high recurrence and treatment resistance. Psilocybin-assisted therapy (PAT) shows promise in reducing depressive symptoms, but long-term effects are unknown. We aimed to determine the long-term safety and efficacy of PAT for MDD over a five-year follow-up period.MethodsIndividuals who previously participated in an RCT studying the effects of PAT for…

  • The Epidemiology of Psychedelic Use Among United States Military Veterans

    Open AccessA K Davis, Mark J Bates et al.ARTICLEJournal of Psychoactive Drugs2024

    We sought to identify patterns of psychedelic use among United States military veterans, compare demographic variables and perspectives of those who did and did not report use, and characterize benefits and adverse outcomes associated with use. Respondents ( N = 426) were recruited to complete an online cross-sectional survey. Approximately one-half (51%) reported using psychedelics. Most did so for healing/treatment (70%) and/or spiritual purpos…

  • Naturalistic psilocybin use is associated with persisting improvements in mental health and wellbeing

    Open AccessSandeep M Nayak, Hillary Jackson et al.ARTICLEFrontiers in Psychiatry2023

    Results from this study, the largest prospective survey of naturalistic psilocybin use to date, support the potential for psilocybin to produce lasting improvements in mental health symptoms and general wellbeing

  • Translation and Initial Psychometric Evaluation of Spanish Versions of Three Psychedelic Acute Effects Measures

    Open AccessA K Davis, Christopher Timmermann et al.ARTICLEJournal of Psychoactive Drugs2023

    This study translated and tested the psychometric properties of acute psychedelic effects measures among Spanish-speaking people. The Psychological Insight Questionnaire (PIQ), Challenging Experiences Questionnaire (CEQ), and Mystical Experiences Questionnaire (MEQ) were translated before being incorporated into a web-based survey. We recruited native Spanish-speakers ( N = 442; M age = 30.8, SD = 10.9; Latino/Latina = 62%; Hispanic = 91.4%; male…

  • Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder

    Open AccessA K Davis, Frederick S Barrett et al.ARTICLEJAMA Psychiatry2021

    ClinicalTrials.gov Identifier: NCT03181529.

  • People of color in North America report improvements in racial trauma and mental health symptoms following psychedelic experiences

    Open AccessM T Williams, A K Davis et al.ARTICLEDrugs Education Prevention and…2021

    This study examined how psychedelics reduced symptoms of racial trauma among black, indigenous, and people of color (BIPOC) subsequent to an experience of racism. A cross-sectional internet-based survey included questions about experiences with racism, mental health symptoms, and acute and enduring psychedelic effects. Changes in mental health were assessed by retrospective report of symptoms in the 30 days before and 30 days after an experience …

  • Inhaled 5-methoxy-N,N-dimethyltryptamine

    Open AccessNathan D Sepeda, John M Clifton et al.ARTICLEJournal of Psychedelic Studies2020Cited by: 1References: 32

    Background and aims 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a potent, short-acting psychedelic that produces strong hallucinogenic effects. The association between the context (i.e., set and setting) of 5-MeO-DMT use and the acute and enduring effects of the substance is unknown. Therefore, this study examined these associations using secondary data from two cross-sectional survey studies. Methods The acute and enduring effects of inhaled…