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Michael A Province

Biographic Data

ID3862424
NAMEMichael A Province
GIVEN NAMESMichael A
FAMILY NAMEProvince
SIGNATUREPROVINCE M A
AFFILIATIONSWashington University in St. Louis
ORCID0000-0001-6102-774X
VERIFIEDYes
TOTAL WORKS11
TOTAL CITATIONS24
WORKS AS AUTHOR11
WORKS AS EDITOR0
FIRST PUBLICATION YEAR1990
LATEST PUBLICATION YEAR2022
H-INDEX1
  • Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

    Open Access•Aysu Okbay, Yeda Wu et al.•ARTICLE•Nature Genetics•2022

    We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…

  • Combined Effect of Lead Exposure and Allostatic Load on Cardiovascular Disease Mortality—A Preliminary Study

    Open Access•Emmanuel Obeng-Gyasi, Alesia Ferguson et al.•ARTICLE•International Journal of…•2021

    This study explores the combined effect of lead (Pb) exposure and an index of chronic physiological stress on cardiovascular disease mortality using data from the National Health and Nutrition Examination Survey (NHANES) 1999-2008 linked to 1999-2014 National Death Index data. Chronic physiological stress was measured using the allostatic load (AL) index, which was formed by analyzing markers from the cardiovascular, inflammatory, and metabolic s…

  • Genetic evidence of assortative mating in humans

    Open Access•M R Robinson, Aaron Kleinman et al.•ARTICLE•Nature Human Behaviour•2017•Cited by: 23•References: 49

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Open Access•Aysu Okbay, Jonathan P Beauchamp et al.•ARTICLE•Nature•2016

  • Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies

    Open Access•Hua Tang, Tom Quertermous et al.•ARTICLE•The American Journal of Human…•2005

  • Familial resemblance in fatness and fat distribution

    Open Access•P T Katzmarzyk, Robert M Malina et al.•ARTICLE•American Journal of Human Biology•2000

    The purpose of the study was to estimate the degree of familial resemblance in anthropometric indicators of fatness and fat distribution. The sample consisted of 327 Caucasian participants from 102 nuclear families. Indicators of fatness included the body mass index (BMI), the sum of six skinfolds (SF6: triceps + biceps + medial calf + subscapular + suprailiac + abdominal), and waist circumference (WAIST), while indicators of fat distribution inc…

  • Familial Resemblance for Hostility

    Gerdi Weidner, Treva Rice et al.•ARTICLE•Psychosomatic Medicine•2000

    OBJECTIVE: The purpose of this study was to examine whether several aspects of hostility as measured by the Cook-Medley Hostility Scale (ie, aggressive responding, hostile affect, cynicism, and overall hostility score) were determined in part by family factors (ie, genes and/or familial environments). METHODS: Analyses were based on 680 European-American families (2525 individuals) from the NHLBI Family Heart Study (FHS), a population-based study…

  • Selected antepartum medical complications and very-low-birthweight infants among black and white women

    M DeBaun, Michael R Debaun et al.•ARTICLE•American Journal of Public Health•1994•Cited by: 1•References: 3

    This study estimated the risk of very-low-birthweight delivery among Black and White women with selected treatable antepartum medical conditions. A logistic regression model was applied to a retrospective, population-based data set identified by computerized, linked birth certificate and maternal hospital discharge records. For Black mothers, the adjusted odds ratio for very-low-birthweight delivery was statistically significant for essential hyp…

  • Heterogeneity among populations for familial aggregation of blood pressure

    Open Access•Treva Rice, Michael A Province et al.•ARTICLE•American Journal of Human Biology•1991

    A simple model of familial aggregation was applied to age–sex corrected systolic (SBP) and diastolic (DBP) blood pressure data from two separate studies: The Québec Family Study and the Tecumseh Community Health Study. Examination of the familial correlations suggested heterogeneity across studies in all DBP correlations, but for SBP only spouse correlations were higher in Québec. Fitting the path model to the data revealed that the only source o…

  • A commingling analysis of obesity in the Tecumseh community health study

    Open Access•Michael A Province, J Keller et al.•ARTICLE•American Journal of Human Biology•1991

    A commingling analysis of the distributions of obesity as quantified by Quetelet's index, triceps skinfold, suprailiac skinfold, umbilical skinfold, subscapular skinfold, a trunk‐extremity ratio of skinfold measurements and Quetelet‐adjusted trunk‐extremity ratio was performed in a population of 9,226 individuals living in Tecumseh, Michigan, during 1962–1965. For all but the (non‐Quetelet‐adjusted) trunk‐extremity ratio, two or three distributio…

  • Commingling analysis of blood pressure in the Tecumseh community health study

    Open Access•Michael A Province, J Keller et al.•ARTICLE•American Journal of Human Biology•1990

    A commingling analysis of the distribution of systolic and diastolic blood pressure was performed on measurements from 9,226 individuals living in Tecumseh, Michigan during 1962–1965. Even after correcting for skewness in the distributions, multiple normal distributions fit the data significantly better than a single normal one, suggesting some level of commingling. The exact nature of the components differed depending on the phenotype, and the n…

  • Genetic evidence of assortative mating in humans

    Open Access•M R Robinson, Aaron Kleinman et al.•ARTICLE•Nature Human Behaviour•2017•Cited by: 23•References: 49

  • Selected antepartum medical complications and very-low-birthweight infants among black and white women

    M DeBaun, Michael R Debaun et al.•ARTICLE•American Journal of Public Health•1994•Cited by: 1•References: 3

    This study estimated the risk of very-low-birthweight delivery among Black and White women with selected treatable antepartum medical conditions. A logistic regression model was applied to a retrospective, population-based data set identified by computerized, linked birth certificate and maternal hospital discharge records. For Black mothers, the adjusted odds ratio for very-low-birthweight delivery was statistically significant for essential hyp…

  • Commingling analysis of blood pressure in the Tecumseh community health study

    Open Access•Michael A Province, J Keller et al.•ARTICLE•American Journal of Human Biology•1990

    A commingling analysis of the distribution of systolic and diastolic blood pressure was performed on measurements from 9,226 individuals living in Tecumseh, Michigan during 1962–1965. Even after correcting for skewness in the distributions, multiple normal distributions fit the data significantly better than a single normal one, suggesting some level of commingling. The exact nature of the components differed depending on the phenotype, and the n…

  • Heterogeneity among populations for familial aggregation of blood pressure

    Open Access•Treva Rice, Michael A Province et al.•ARTICLE•American Journal of Human Biology•1991

    A simple model of familial aggregation was applied to age–sex corrected systolic (SBP) and diastolic (DBP) blood pressure data from two separate studies: The Québec Family Study and the Tecumseh Community Health Study. Examination of the familial correlations suggested heterogeneity across studies in all DBP correlations, but for SBP only spouse correlations were higher in Québec. Fitting the path model to the data revealed that the only source o…

  • A commingling analysis of obesity in the Tecumseh community health study

    Open Access•Michael A Province, J Keller et al.•ARTICLE•American Journal of Human Biology•1991

    A commingling analysis of the distributions of obesity as quantified by Quetelet's index, triceps skinfold, suprailiac skinfold, umbilical skinfold, subscapular skinfold, a trunk‐extremity ratio of skinfold measurements and Quetelet‐adjusted trunk‐extremity ratio was performed in a population of 9,226 individuals living in Tecumseh, Michigan, during 1962–1965. For all but the (non‐Quetelet‐adjusted) trunk‐extremity ratio, two or three distributio…

  • Selected antepartum medical complications and very-low-birthweight infants among black and white women

    M DeBaun, Michael R Debaun et al.•ARTICLE•American Journal of Public Health•1994•Cited by: 1•References: 3

    This study estimated the risk of very-low-birthweight delivery among Black and White women with selected treatable antepartum medical conditions. A logistic regression model was applied to a retrospective, population-based data set identified by computerized, linked birth certificate and maternal hospital discharge records. For Black mothers, the adjusted odds ratio for very-low-birthweight delivery was statistically significant for essential hyp…

  • Familial resemblance in fatness and fat distribution

    Open Access•P T Katzmarzyk, Robert M Malina et al.•ARTICLE•American Journal of Human Biology•2000

    The purpose of the study was to estimate the degree of familial resemblance in anthropometric indicators of fatness and fat distribution. The sample consisted of 327 Caucasian participants from 102 nuclear families. Indicators of fatness included the body mass index (BMI), the sum of six skinfolds (SF6: triceps + biceps + medial calf + subscapular + suprailiac + abdominal), and waist circumference (WAIST), while indicators of fat distribution inc…

  • Familial Resemblance for Hostility

    Gerdi Weidner, Treva Rice et al.•ARTICLE•Psychosomatic Medicine•2000

    OBJECTIVE: The purpose of this study was to examine whether several aspects of hostility as measured by the Cook-Medley Hostility Scale (ie, aggressive responding, hostile affect, cynicism, and overall hostility score) were determined in part by family factors (ie, genes and/or familial environments). METHODS: Analyses were based on 680 European-American families (2525 individuals) from the NHLBI Family Heart Study (FHS), a population-based study…

  • Genetic Structure, Self-Identified Race/Ethnicity, and Confounding in Case-Control Association Studies

    Open Access•Hua Tang, Tom Quertermous et al.•ARTICLE•The American Journal of Human…•2005

  • Genome-wide association study identifies 74 loci associated with educational attainment

    Open Access•Aysu Okbay, Jonathan P Beauchamp et al.•ARTICLE•Nature•2016

  • Genetic evidence of assortative mating in humans

    Open Access•M R Robinson, Aaron Kleinman et al.•ARTICLE•Nature Human Behaviour•2017•Cited by: 23•References: 49

  • Combined Effect of Lead Exposure and Allostatic Load on Cardiovascular Disease Mortality—A Preliminary Study

    Open Access•Emmanuel Obeng-Gyasi, Alesia Ferguson et al.•ARTICLE•International Journal of…•2021

    This study explores the combined effect of lead (Pb) exposure and an index of chronic physiological stress on cardiovascular disease mortality using data from the National Health and Nutrition Examination Survey (NHANES) 1999-2008 linked to 1999-2014 National Death Index data. Chronic physiological stress was measured using the allostatic load (AL) index, which was formed by analyzing markers from the cardiovascular, inflammatory, and metabolic s…

  • Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals

    Open Access•Aysu Okbay, Yeda Wu et al.•ARTICLE•Nature Genetics•2022

    We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…

Biology (8 works) · Medicine (7 works) · Demography (6 works) · Genetic Associations and Epidemiology (6 works) · Population (6 works) · Genetics (4 works) · Internal Medicine (4 works) · Birth, Development, and Health (3 works) · Environmental health (3 works) · Gene (3 works)

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