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Nakao Iwata

Biographic Data

ID3863417
NAMENakao Iwata
GIVEN NAMESNakao
FAMILY NAMEIwata
SIGNATUREIWATA N
AFFILIATIONSFujita Health University
ORCID0000-0003-3189-6076
VERIFIEDYes
TOTAL WORKS10
TOTAL CITATIONS7
AUTHOR COUNT10
EDITOR COUNT0
FIRST PUBLICATION YEAR2017
LATEST PUBLICATION YEAR2025
H-INDEX2
  • Estimating the incidence of actionable drug-gene interactions in Japanese patients with major depressive disorder

    Open Access•Masakazu Hatano, Masashi Ikeda et al.•ARTICLE•Frontiers in Psychiatry•2025

    We estimated that one in four Japanese patients with major depressive disorder who were prescribed first-time antidepressants had actionable drug-gene interactions. These results suggest that pre-emptive pharmacogenetic testing in the treatment of major depressive disorder could have important clinical implications

  • Association between decreased taurine levels in the anterior cingulate cortex and restricted and repetitive behaviors in autism spectrum disorder: A cross-sectional study

    Open Access•Akihiro Minami, Kiwamu Matsuoka et al.•ARTICLE•Frontiers in Psychiatry•2025

    These findings suggest that reduced taurine levels in the ACC of children with ASD, alongside unchanged GSH levels, may indicate distinct biosynthetic pathways and functional roles of these metabolites in oxidative stress defense mechanisms associated with ASD pathology. Taurine depletion may disrupt physiological processes associated with RRBs and could serve as a potential therapeutic target for symptom management

  • Reduced prefrontal hemodynamic responses measured using near-infrared spectroscopy in adults with autism spectrum disorder

    Open Access•Kohei Kamikawa, Kazuhiko Yamamuro et al.•ARTICLE•Frontiers in Psychiatry•2025

    Adults with ASD have reduced prefrontal hemodynamic responses as measured using near-infrared spectroscopy and the reduced activity of the frontal pole in particular is related to reduced attentional function

  • Physical, Psychiatric, and Social Comorbidities of Individuals with Schizophrenia Living in the Community in Japan

    Open Access•Masaaki Matsunaga, Yuanying Li et al.•ARTICLE•International Journal of…•2023

    The physical, psychiatric, and social comorbidities interfere with the everyday activities of community-dwelling individuals with schizophrenia and increase the risk of their readmission. However, these comorbidities have not been investigated comprehensively in Japan. We conducted a self-reported internet survey in February 2022 to identify individuals aged 20-75 years with and without schizophrenia using a prevalence case-control study. The sur…

  • Mapping genomic loci implicates genes and synaptic biology in schizophrenia

    Open Access•Vassily Trubetskoy, Antonio F Pardiñas et al.•ARTICLE•Nature•2022

  • Altered distribution of resting periods of daily locomotor activity in patients with delayed sleep phase disorder

    Open Access•Marina Hirose, Toru Nakamura et al.•ARTICLE•Frontiers in Psychiatry•2022

    Delayed sleep phase disorder (DSPD) and mood disorders have a close relationship. However, the shared mechanisms by DSPD and mood disorders have not been well-elucidated. We previously found that micro-fluctuations in human behaviors are organized by robust statistical laws (behavioral organization), where the cumulative distributions of resting and active period durations take a power-law distribution form and a stretched exponential functional …

  • GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits

    Open Access•Nana Matoba, Masahiro Akiyama et al.•ARTICLE•Nature Human Behaviour•2020•Cited by: 4•References: 48

  • GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture

    Open Access•Nana Matoba, Masahiro Akiyama et al.•ARTICLE•Nature Human Behaviour•2019•Cited by: 3•References: 51

  • Serum Brain-Derived Neurotrophic Factor, and Plasma Catecholamine Metabolites in People with Major Depression: Preliminary Cross-Sectional Study

    Open Access•Reiji Yoshimura, Taro Kishi et al.•ARTICLE•Frontiers in Psychiatry•2018

    The results suggest that there are no significant correlations between catecholamine metabolites and BDNF in the blood for MDD patients

  • Verbal Memory Impairment in Patients with Subsyndromal Bipolar Disorder

    Open Access•Tomiki Sumiyoshi, Atsuhito Toyomaki et al.•ARTICLE•Frontiers in Psychiatry•2017

    These results suggest the CVLT-II Japanese version is able to discriminate between bipolar disorder patients and healthy controls with good sensitivity and validity. Data in this study also indicate that the degree of verbal memory deficits in bipolar disorder may be influenced by memory organizational strategy

  • GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits

    Open Access•Nana Matoba, Masahiro Akiyama et al.•ARTICLE•Nature Human Behaviour•2020•Cited by: 4•References: 48

  • GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture

    Open Access•Nana Matoba, Masahiro Akiyama et al.•ARTICLE•Nature Human Behaviour•2019•Cited by: 3•References: 51

  • Verbal Memory Impairment in Patients with Subsyndromal Bipolar Disorder

    Open Access•Tomiki Sumiyoshi, Atsuhito Toyomaki et al.•ARTICLE•Frontiers in Psychiatry•2017

    These results suggest the CVLT-II Japanese version is able to discriminate between bipolar disorder patients and healthy controls with good sensitivity and validity. Data in this study also indicate that the degree of verbal memory deficits in bipolar disorder may be influenced by memory organizational strategy

  • Serum Brain-Derived Neurotrophic Factor, and Plasma Catecholamine Metabolites in People with Major Depression: Preliminary Cross-Sectional Study

    Open Access•Reiji Yoshimura, Taro Kishi et al.•ARTICLE•Frontiers in Psychiatry•2018

    The results suggest that there are no significant correlations between catecholamine metabolites and BDNF in the blood for MDD patients

  • GWAS of smoking behaviour in 165,436 Japanese people reveals seven new loci and shared genetic architecture

    Open Access•Nana Matoba, Masahiro Akiyama et al.•ARTICLE•Nature Human Behaviour•2019•Cited by: 3•References: 51

  • GWAS of 165,084 Japanese individuals identified nine loci associated with dietary habits

    Open Access•Nana Matoba, Masahiro Akiyama et al.•ARTICLE•Nature Human Behaviour•2020•Cited by: 4•References: 48

  • Mapping genomic loci implicates genes and synaptic biology in schizophrenia

    Open Access•Vassily Trubetskoy, Antonio F Pardiñas et al.•ARTICLE•Nature•2022

  • Altered distribution of resting periods of daily locomotor activity in patients with delayed sleep phase disorder

    Open Access•Marina Hirose, Toru Nakamura et al.•ARTICLE•Frontiers in Psychiatry•2022

    Delayed sleep phase disorder (DSPD) and mood disorders have a close relationship. However, the shared mechanisms by DSPD and mood disorders have not been well-elucidated. We previously found that micro-fluctuations in human behaviors are organized by robust statistical laws (behavioral organization), where the cumulative distributions of resting and active period durations take a power-law distribution form and a stretched exponential functional …

  • Physical, Psychiatric, and Social Comorbidities of Individuals with Schizophrenia Living in the Community in Japan

    Open Access•Masaaki Matsunaga, Yuanying Li et al.•ARTICLE•International Journal of…•2023

    The physical, psychiatric, and social comorbidities interfere with the everyday activities of community-dwelling individuals with schizophrenia and increase the risk of their readmission. However, these comorbidities have not been investigated comprehensively in Japan. We conducted a self-reported internet survey in February 2022 to identify individuals aged 20-75 years with and without schizophrenia using a prevalence case-control study. The sur…

  • Estimating the incidence of actionable drug-gene interactions in Japanese patients with major depressive disorder

    Open Access•Masakazu Hatano, Masashi Ikeda et al.•ARTICLE•Frontiers in Psychiatry•2025

    We estimated that one in four Japanese patients with major depressive disorder who were prescribed first-time antidepressants had actionable drug-gene interactions. These results suggest that pre-emptive pharmacogenetic testing in the treatment of major depressive disorder could have important clinical implications

  • Association between decreased taurine levels in the anterior cingulate cortex and restricted and repetitive behaviors in autism spectrum disorder: A cross-sectional study

    Open Access•Akihiro Minami, Kiwamu Matsuoka et al.•ARTICLE•Frontiers in Psychiatry•2025

    These findings suggest that reduced taurine levels in the ACC of children with ASD, alongside unchanged GSH levels, may indicate distinct biosynthetic pathways and functional roles of these metabolites in oxidative stress defense mechanisms associated with ASD pathology. Taurine depletion may disrupt physiological processes associated with RRBs and could serve as a potential therapeutic target for symptom management

  • Reduced prefrontal hemodynamic responses measured using near-infrared spectroscopy in adults with autism spectrum disorder

    Open Access•Kohei Kamikawa, Kazuhiko Yamamuro et al.•ARTICLE•Frontiers in Psychiatry•2025

    Adults with ASD have reduced prefrontal hemodynamic responses as measured using near-infrared spectroscopy and the reduced activity of the frontal pole in particular is related to reduced attentional function

Medicine (8 works) · Psychiatry (6 works) · Psychology (5 works) · Biology (4 works) · Clinical Psychology (4 works) · Clinical Psychology (4 works) · Gene (4 works) · Genetic Associations and Epidemiology (3 works) · Genetics (3 works) · Genotype (3 works)

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