Harald H H Göring
Biographic Data
| ID | 4089809 |
|---|---|
| NAME | Harald H H Göring |
| GIVEN NAMES | Harald H H |
| FAMILY NAME | Göring |
| SIGNATURE | GORING H H H |
| AFFILIATIONS | Texas Biomedical Research Institute |
| VERIFIED | No |
| TOTAL WORKS | 5 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 5 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2009 |
| LATEST PUBLICATION YEAR | 2011 |
| H-INDEX | 0 |
Genetic influences on serum bilirubin in American Indians: The strong heart family study
OBJECTIVE: To identify genetic variation influencing serum bilirubin levels in American Indians, we performed genome-wide screening and association analyses in the Strong Heart Family Study. Bilirubin is an endogenous antioxidant that has demonstrated an inverse relationship with cardiovascular disease. Genetic variation within the promoter region of uridine diphosphate glucuronosyltransferase (UGT1A1) on chromosome 2q has been associated with el…
Quantitative Trait Nucleotide Analysis Using Bayesian Model Selection
Although much attention has been given to statistical genetic methods for the initial localization and fine mapping of quantitative trait loci (QTLs), little methodological work has been done to date on the problem of statistically identifying the most likely functional polymorphisms using sequence data. In this paper we provide a general statistical genetic framework, called Bayesian quantitative trait nucleotide (BQTN) analysis, for assessing t…
Update to Terwilliger and Göring's “Gene Mapping in the 20th and 21st Centuries” (2000): Gene Mapping When Rare Variants Are Common and Common Variants Are Rare
Our Lasker Prize winning article from 2000 was a discussion of the myriad factors that influence the success or failure of gene mapping studies, and in it we sug- gested that the reasons we geneticists have had so little success in unraveling the etiology of complex traits had more to do with biology than technology and that many of the decisions about future strategies were being made based on unrealis- tic and untested assumptions. At the time,…
Update to Terwilliger and Göring's "Gene Mapping in the 20th and 21st Centuries" (2000): Gene Mapping When Rare Variants Are Common and Common Variants Are Rare
Update to Terwilliger and Göring's "Gene Mapping in the 20th and 21st Centuries" (2000):Gene Mapping When Rare Variants Are Common and Common Variants Are Rare Joseph D. Terwilliger and Harald H. H. Göring Keywords Gene Mapping, Common Variant/Common Disease (CVCD) Hypothesis, Complex Disease Genetics, Study Design Our Lasker Prize winning article from 2000 was a discussion of the myriad factors that influence the success or failure of gene mappi…
Gene Mapping in the 20th and 21st Centuries: Statistical Methods, Data Analysis, and Experimental Design
In the 20th century geneticists began to unravel some of the simpler aspects of the etiology of inherited diseases in humans. The theory of linkage analysis was developed and applied long before the advent of molecular biology, but only the technological advances of the second half of the 20th century made large-scale gene mapping with a dense genome-spanning set of markers a reality. More recently, the primary topic of interest has shifted from …
No prominent works on this page.
Quantitative Trait Nucleotide Analysis Using Bayesian Model Selection
Although much attention has been given to statistical genetic methods for the initial localization and fine mapping of quantitative trait loci (QTLs), little methodological work has been done to date on the problem of statistically identifying the most likely functional polymorphisms using sequence data. In this paper we provide a general statistical genetic framework, called Bayesian quantitative trait nucleotide (BQTN) analysis, for assessing t…
Update to Terwilliger and Göring's “Gene Mapping in the 20th and 21st Centuries” (2000): Gene Mapping When Rare Variants Are Common and Common Variants Are Rare
Our Lasker Prize winning article from 2000 was a discussion of the myriad factors that influence the success or failure of gene mapping studies, and in it we sug- gested that the reasons we geneticists have had so little success in unraveling the etiology of complex traits had more to do with biology than technology and that many of the decisions about future strategies were being made based on unrealis- tic and untested assumptions. At the time,…
Update to Terwilliger and Göring's "Gene Mapping in the 20th and 21st Centuries" (2000): Gene Mapping When Rare Variants Are Common and Common Variants Are Rare
Update to Terwilliger and Göring's "Gene Mapping in the 20th and 21st Centuries" (2000):Gene Mapping When Rare Variants Are Common and Common Variants Are Rare Joseph D. Terwilliger and Harald H. H. Göring Keywords Gene Mapping, Common Variant/Common Disease (CVCD) Hypothesis, Complex Disease Genetics, Study Design Our Lasker Prize winning article from 2000 was a discussion of the myriad factors that influence the success or failure of gene mappi…
Gene Mapping in the 20th and 21st Centuries: Statistical Methods, Data Analysis, and Experimental Design
In the 20th century geneticists began to unravel some of the simpler aspects of the etiology of inherited diseases in humans. The theory of linkage analysis was developed and applied long before the advent of molecular biology, but only the technological advances of the second half of the 20th century made large-scale gene mapping with a dense genome-spanning set of markers a reality. More recently, the primary topic of interest has shifted from …
Genetic influences on serum bilirubin in American Indians: The strong heart family study
OBJECTIVE: To identify genetic variation influencing serum bilirubin levels in American Indians, we performed genome-wide screening and association analyses in the Strong Heart Family Study. Bilirubin is an endogenous antioxidant that has demonstrated an inverse relationship with cardiovascular disease. Genetic variation within the promoter region of uridine diphosphate glucuronosyltransferase (UGT1A1) on chromosome 2q has been associated with el…
Biology (5 works) · Gene (5 works) · Genetics (5 works) · Evolutionary biology (4 works) · Computational biology (3 works) · Computer Science (3 works) · Genetic Associations and Epidemiology (3 works) · Genetics (3 works) · Demography (2 works) · Disease (2 works)