Ramiro Barrantes
Biographic Data
| ID | 4090766 |
|---|---|
| NAME | Ramiro Barrantes |
| GIVEN NAMES | Ramiro |
| FAMILY NAME | Barrantes |
| SIGNATURE | BARRANTES R |
| AFFILIATIONS | Universidad de Costa Rica |
| VERIFIED | No |
| TOTAL WORKS | 18 |
| TOTAL CITATIONS | 34 |
| AUTHOR COUNT | 18 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1982 |
| LATEST PUBLICATION YEAR | 2014 |
| H-INDEX | 4 |
Ancient human genomes suggest three ancestral populations for present-day Europeans
A Mitochondrial Haplogroup Is Associated with Decreased Longevity in a Historic New World Population
Interest in mitochondrial influences on extended longevity has been mounting, as evidenced by a growing literature. Such work has demonstrated that some haplogroups are associated with increased longevity and that such associations are population specific. Most previous work, however, suffers from the methodological shortcoming that long-lived individuals are compared with "controls" who are born decades after the aged individuals. The only true …
Microevolution, migration, and the population structure of five Amerindian populations from Nicaragua and Costa Rica
OBJECTIVE: This research examines the coevolution of languages and uniparental genetic marker (mitochondrial DNA [mtDNA] and nonrecombining Y-chromosome [NRY]) variation within five Lower Central American (Rama, Chorotega, Maléku, Zapatón-Huetar, and Abrojo-Guaymí) Amerindian groups. This pattern occurred since European contact. METHODS: We examined mtDNA sequence variation from the hypervariable region 1 (HVS-1) and NRY genetic variation using s…
Ancestry Informative Markers Clarify the Regional Admixture Variation in the Costa Rican Population
The genetic structure of Costa Rica's population is complex, both by region and by individual, due to the admixture process that started during the 15th century and historical events thereafter. Previous studies have been done mostly on Amerindian populations and the Central Valley inhabitants using various microsatellites and mitochondrial DNA markers. Here, we study for the first time a random sample from all regions of the country with ancestr…
Reconstructing Native American population history
High mitochondrial mutation rates estimated from deep‐rooting costa rican pedigrees
Estimates of mutation rates for the noncoding hypervariable Region I (HVR‐I) of mitochondrial DNA vary widely, depending on whether they are inferred from phylogenies (assuming that molecular evolution is clock‐like) or directly from pedigrees. All pedigree‐based studies so far were conducted on populations of European origin. In this article, we analyzed 19 deep‐rooting pedigrees in a population of mixed origin in Costa Rica. We calculated two e…
Mitochondrial polymorphisms associated with differential longevity do not impact lifetime‐reproductive success
Geographic Patterns of Genome Admixture in Latin American Mestizos
The large and diverse population of Latin America is potentially a powerful resource for elucidating the genetic basis of complex traits through admixture mapping. However, no genome-wide characterization of admixture across Latin America has yet been attempted. Here, we report an analysis of admixture in thirteen Mestizo populations (i.e. in regions of mainly European and Native settlement) from seven countries in Latin America based on data for…
Genetic Variation and Population Structure in Native Americans
We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data available in 54 other indigenous populations worldwide, including an additional five Native American groups. The Native American populations have lower gen…
Indentured migration and differential gender gene flow: The origin and evolution of the East‐Indian community of Limón, Costa Rica
After the emancipation of African slaves in the Caribbean, the labor void left by out‐migrating former slaves was filled by in‐migrating indentured servants from prepartition India and China. In some areas of the Caribbean such as Trinidad, Suriname, and Guyana, the East‐Indian migrants formed large communities. In this article, we report a study based on mtDNA and Y‐chromosomal markers of a small East‐Indian community from Limón, Costa Rica. The…
Genetic Structure Analysis of Three Hispanic Populations from Costa Rica, Mexico, and the Southwestern United States Using Y-Chromosome STR Markers and mtDNA Sequences
Two hundred seventeen male subjects from Costa Rica, Mexico, and the Hispanic population of the southwestern United States were studied. Twelve Y-chromosome STRs and the HVSI sequence of the mtDNA were analyzed to describe their genetic structure and to compare maternal and paternal lineages. All subjects are part of two NIMH-funded studies to localize schizophrenia susceptibility genes in Hispanic populations of Mexican and Central American ance…
Genetic Variation of the Y Chromosome in Chibcha-Speaking Amerindians of Costa Rica and Panama
Genetic variation of the Y chromosome in five Chibchan tribes (Bribri, Cabecar, Guaymi, Huetar, and Teribe) of Costa Rica and Panama was analyzed using six microsatellite loci (DYS19, DYS389A, DYS389B, DYS390, DYS391, and DYS393), the Y-chromosome-specific alphoid system (alphah), the Y-chromosome Alu polymorphism (YAP), and a specific pre-Columbian transition (C-->T) (M3 marker) in the DYS 199 locus that defines the Q-M3 haplogroup. Thirty-nine …
Genetic Variation of Cassava (Manihot Esculenta Crantz) Cultivated by Chibchan Amerindians of Costa Rica
Intra- and Intercontinental Molecular Variability of an Alu Insertion in the 3' Untranslated Region of the LDLR Gene
One-hundred three individuals from two Mongolian, two Siberian, and ten native American populations were studied in relation to a 340-bp sequence from an Alu insertion located in the 3' untranslated region of the LDLR gene. Seven haplotypes have been determined, and haplotype B1 was the most common, accounting for about half the sequences found. In general, diversity values are quite high, about 2.5 times higher than those found in other autosoma…
Species Diversity of Edible Plants Grown in Homegardens of Chibchan Amerindians from Costa Rica
Blood group, red cell, and serum protein variation in the Cabecar and Huetar, two Chibchan Amerindian tribes of Costa Rica
Genetic variation, using blood groups and red cell and serum proteins, was surveyed in the Cabecar of Chirripo and the Huetar of Quitirrisi, Costa Rica. Thirty-nine loci were screened in a sample of 91 Cabecars and 40 loci in 45 Huetars. Twenty-seven loci were monomorphic in the Cabecar and 30 in the Huetar. The proportions of polymorphic loci (P), out of 34 studied by electrophoresis, were 0.235 and 0.177, respectively. Estimated gene diversitie…
Blood group, red cell, and serum protein variation in the Cabecar and Huetar, two Chibchan Amerindian tribes of Costa Rica
Genetic variation, using blood groups and red cell and serum proteins, was surveyed in the Cabecar of Chirripo and the Huetar of Quitirrisi, Costa Rica. Thirty-nine loci were screened in a sample of 91 Cabecars and 40 loci in 45 Huetars. Twenty-seven loci were monomorphic in the Cabecar and 30 in the Huetar. The proportions of polymorphic loci (P), out of 34 studied by electrophoresis, were 0.235 and 0.177, respectively. Estimated gene diversitie…
Migration and genetic infrastructure of the central american guaymi and their affinities with other tribal groups
New genetic data on 40 red cell enzymes, antigenic blood groups, and serum proteins representing 42 separate loci, are reported for two Guaymi communities in Southeastern Costa Rica. These two settlements, Limoncito and Abrojo, are of recent origin, having been established by Panamanian migrants in the last 50 years. Detailed data on the provenance of these migrants permits an analysis of how these settlement patterns differ from those typical of…
Genetic Structure Analysis of Three Hispanic Populations from Costa Rica, Mexico, and the Southwestern United States Using Y-Chromosome STR Markers and mtDNA Sequences
Two hundred seventeen male subjects from Costa Rica, Mexico, and the Hispanic population of the southwestern United States were studied. Twelve Y-chromosome STRs and the HVSI sequence of the mtDNA were analyzed to describe their genetic structure and to compare maternal and paternal lineages. All subjects are part of two NIMH-funded studies to localize schizophrenia susceptibility genes in Hispanic populations of Mexican and Central American ance…
Species Diversity of Edible Plants Grown in Homegardens of Chibchan Amerindians from Costa Rica
Genetic Variation of the Y Chromosome in Chibcha-Speaking Amerindians of Costa Rica and Panama
Genetic variation of the Y chromosome in five Chibchan tribes (Bribri, Cabecar, Guaymi, Huetar, and Teribe) of Costa Rica and Panama was analyzed using six microsatellite loci (DYS19, DYS389A, DYS389B, DYS390, DYS391, and DYS393), the Y-chromosome-specific alphoid system (alphah), the Y-chromosome Alu polymorphism (YAP), and a specific pre-Columbian transition (C-->T) (M3 marker) in the DYS 199 locus that defines the Q-M3 haplogroup. Thirty-nine …
Migration and genetic infrastructure of the central american guaymi and their affinities with other tribal groups
New genetic data on 40 red cell enzymes, antigenic blood groups, and serum proteins representing 42 separate loci, are reported for two Guaymi communities in Southeastern Costa Rica. These two settlements, Limoncito and Abrojo, are of recent origin, having been established by Panamanian migrants in the last 50 years. Detailed data on the provenance of these migrants permits an analysis of how these settlement patterns differ from those typical of…
Indentured migration and differential gender gene flow: The origin and evolution of the East‐Indian community of Limón, Costa Rica
After the emancipation of African slaves in the Caribbean, the labor void left by out‐migrating former slaves was filled by in‐migrating indentured servants from prepartition India and China. In some areas of the Caribbean such as Trinidad, Suriname, and Guyana, the East‐Indian migrants formed large communities. In this article, we report a study based on mtDNA and Y‐chromosomal markers of a small East‐Indian community from Limón, Costa Rica. The…
High mitochondrial mutation rates estimated from deep‐rooting costa rican pedigrees
Estimates of mutation rates for the noncoding hypervariable Region I (HVR‐I) of mitochondrial DNA vary widely, depending on whether they are inferred from phylogenies (assuming that molecular evolution is clock‐like) or directly from pedigrees. All pedigree‐based studies so far were conducted on populations of European origin. In this article, we analyzed 19 deep‐rooting pedigrees in a population of mixed origin in Costa Rica. We calculated two e…
Genetic Variation of Cassava (Manihot Esculenta Crantz) Cultivated by Chibchan Amerindians of Costa Rica
Migration and genetic infrastructure of the central american guaymi and their affinities with other tribal groups
New genetic data on 40 red cell enzymes, antigenic blood groups, and serum proteins representing 42 separate loci, are reported for two Guaymi communities in Southeastern Costa Rica. These two settlements, Limoncito and Abrojo, are of recent origin, having been established by Panamanian migrants in the last 50 years. Detailed data on the provenance of these migrants permits an analysis of how these settlement patterns differ from those typical of…
Blood group, red cell, and serum protein variation in the Cabecar and Huetar, two Chibchan Amerindian tribes of Costa Rica
Genetic variation, using blood groups and red cell and serum proteins, was surveyed in the Cabecar of Chirripo and the Huetar of Quitirrisi, Costa Rica. Thirty-nine loci were screened in a sample of 91 Cabecars and 40 loci in 45 Huetars. Twenty-seven loci were monomorphic in the Cabecar and 30 in the Huetar. The proportions of polymorphic loci (P), out of 34 studied by electrophoresis, were 0.235 and 0.177, respectively. Estimated gene diversitie…
Blood group, red cell, and serum protein variation in the Cabecar and Huetar, two Chibchan Amerindian tribes of Costa Rica
Genetic variation, using blood groups and red cell and serum proteins, was surveyed in the Cabecar of Chirripo and the Huetar of Quitirrisi, Costa Rica. Thirty-nine loci were screened in a sample of 91 Cabecars and 40 loci in 45 Huetars. Twenty-seven loci were monomorphic in the Cabecar and 30 in the Huetar. The proportions of polymorphic loci (P), out of 34 studied by electrophoresis, were 0.235 and 0.177, respectively. Estimated gene diversitie…
Species Diversity of Edible Plants Grown in Homegardens of Chibchan Amerindians from Costa Rica
Genetic Variation of Cassava (Manihot Esculenta Crantz) Cultivated by Chibchan Amerindians of Costa Rica
Intra- and Intercontinental Molecular Variability of an Alu Insertion in the 3' Untranslated Region of the LDLR Gene
One-hundred three individuals from two Mongolian, two Siberian, and ten native American populations were studied in relation to a 340-bp sequence from an Alu insertion located in the 3' untranslated region of the LDLR gene. Seven haplotypes have been determined, and haplotype B1 was the most common, accounting for about half the sequences found. In general, diversity values are quite high, about 2.5 times higher than those found in other autosoma…
Genetic Variation of the Y Chromosome in Chibcha-Speaking Amerindians of Costa Rica and Panama
Genetic variation of the Y chromosome in five Chibchan tribes (Bribri, Cabecar, Guaymi, Huetar, and Teribe) of Costa Rica and Panama was analyzed using six microsatellite loci (DYS19, DYS389A, DYS389B, DYS390, DYS391, and DYS393), the Y-chromosome-specific alphoid system (alphah), the Y-chromosome Alu polymorphism (YAP), and a specific pre-Columbian transition (C-->T) (M3 marker) in the DYS 199 locus that defines the Q-M3 haplogroup. Thirty-nine …
Genetic Structure Analysis of Three Hispanic Populations from Costa Rica, Mexico, and the Southwestern United States Using Y-Chromosome STR Markers and mtDNA Sequences
Two hundred seventeen male subjects from Costa Rica, Mexico, and the Hispanic population of the southwestern United States were studied. Twelve Y-chromosome STRs and the HVSI sequence of the mtDNA were analyzed to describe their genetic structure and to compare maternal and paternal lineages. All subjects are part of two NIMH-funded studies to localize schizophrenia susceptibility genes in Hispanic populations of Mexican and Central American ance…
Genetic Variation and Population Structure in Native Americans
We examined genetic diversity and population structure in the American landmass using 678 autosomal microsatellite markers genotyped in 422 individuals representing 24 Native American populations sampled from North, Central, and South America. These data were analyzed jointly with similar data available in 54 other indigenous populations worldwide, including an additional five Native American groups. The Native American populations have lower gen…
Indentured migration and differential gender gene flow: The origin and evolution of the East‐Indian community of Limón, Costa Rica
After the emancipation of African slaves in the Caribbean, the labor void left by out‐migrating former slaves was filled by in‐migrating indentured servants from prepartition India and China. In some areas of the Caribbean such as Trinidad, Suriname, and Guyana, the East‐Indian migrants formed large communities. In this article, we report a study based on mtDNA and Y‐chromosomal markers of a small East‐Indian community from Limón, Costa Rica. The…
Geographic Patterns of Genome Admixture in Latin American Mestizos
The large and diverse population of Latin America is potentially a powerful resource for elucidating the genetic basis of complex traits through admixture mapping. However, no genome-wide characterization of admixture across Latin America has yet been attempted. Here, we report an analysis of admixture in thirteen Mestizo populations (i.e. in regions of mainly European and Native settlement) from seven countries in Latin America based on data for…
Mitochondrial polymorphisms associated with differential longevity do not impact lifetime‐reproductive success
Reconstructing Native American population history
High mitochondrial mutation rates estimated from deep‐rooting costa rican pedigrees
Estimates of mutation rates for the noncoding hypervariable Region I (HVR‐I) of mitochondrial DNA vary widely, depending on whether they are inferred from phylogenies (assuming that molecular evolution is clock‐like) or directly from pedigrees. All pedigree‐based studies so far were conducted on populations of European origin. In this article, we analyzed 19 deep‐rooting pedigrees in a population of mixed origin in Costa Rica. We calculated two e…
Microevolution, migration, and the population structure of five Amerindian populations from Nicaragua and Costa Rica
OBJECTIVE: This research examines the coevolution of languages and uniparental genetic marker (mitochondrial DNA [mtDNA] and nonrecombining Y-chromosome [NRY]) variation within five Lower Central American (Rama, Chorotega, Maléku, Zapatón-Huetar, and Abrojo-Guaymí) Amerindian groups. This pattern occurred since European contact. METHODS: We examined mtDNA sequence variation from the hypervariable region 1 (HVS-1) and NRY genetic variation using s…
Ancestry Informative Markers Clarify the Regional Admixture Variation in the Costa Rican Population
The genetic structure of Costa Rica's population is complex, both by region and by individual, due to the admixture process that started during the 15th century and historical events thereafter. Previous studies have been done mostly on Amerindian populations and the Central Valley inhabitants using various microsatellites and mitochondrial DNA markers. Here, we study for the first time a random sample from all regions of the country with ancestr…
Ancient human genomes suggest three ancestral populations for present-day Europeans
A Mitochondrial Haplogroup Is Associated with Decreased Longevity in a Historic New World Population
Interest in mitochondrial influences on extended longevity has been mounting, as evidenced by a growing literature. Such work has demonstrated that some haplogroups are associated with increased longevity and that such associations are population specific. Most previous work, however, suffers from the methodological shortcoming that long-lived individuals are compared with "controls" who are born decades after the aged individuals. The only true …
Biology (15 works) · Population (14 works) · Demography (13 works) · Evolutionary biology (12 works) · Forensic and Genetic Research (12 works) · Gene (12 works) · Genetics (10 works) · Genetics (9 works) · Geography (8 works) · Allele (6 works)