Sergio Tofanelli
Biographic Data
| ID | 4091048 |
|---|---|
| NAME | Sergio Tofanelli |
| GIVEN NAMES | Sergio |
| FAMILY NAME | Tofanelli |
| SIGNATURE | TOFANELLI S |
| AFFILIATIONS | University of Pisa |
| ORCID | 0000-0002-7399-9308 |
| VERIFIED | Yes |
| TOTAL WORKS | 15 |
| TOTAL CITATIONS | 19 |
| AUTHOR COUNT | 15 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1993 |
| LATEST PUBLICATION YEAR | 2017 |
| H-INDEX | 4 |
A bio-cultural approach to the study of food choice: The contribution of taste genetics, population and culture
Stuck in fragments: Population genetics of the Endangered collared brown lemur Eulemur collaris in the Malagasy littoral forest
OBJECTIVES: The Endangered collared brown lemur (Eulemur collaris) is the largest primate living in the littoral forest of southeastern Madagascar, a top priority habitat for biodiversity conservation on the island. Because this lemur is a key seed-disperser, an evaluation of the structure and connectivity of the populations surviving in the forest fragments is urgently needed to guide conservation plans. MATERIALS AND METHODS: Genetic variabilit…
Increased efficiency in geographic ancestry assignment and human identification by combining lineage profiles: The case of the iranians
OBJECTIVES: This research is a first empirical attempt to quantify the increase of the among-groups variance and the probative value of a DNA evidence when combining profiles based on markers with uniparental inheritance. METHODS: Yfiler and HVS-I panels of loci were analyzed in 130 healthy unrelated males from six Iranian native groups. RESULTS: A separate analysis of DNA profiles at the two lineage markers failed to detect a population substruc…
The dual origin of tati‐speakers from dagestan as written in the genealogy of uniparental variants
The independent demographic histories of the two samples, with mutually reversed profiles at paternally and maternally transmitted genetic systems, suggest that geographic proximity and linguistic assimilation of Tati-speakers from Dagestan do not reflect a common ancestry
MtDNA variability in two Bantu‐speaking populations (Shona and Hutu) from Eastern Africa: Implications for peopling and migration patterns in sub‐Saharan Africa
In this study, we report novel data on mitochondrial DNA in two of the largest eastern Bantu‐speaking populations, the Shona from Zimbabwe and the Hutu from Rwanda. The goal is to evaluate the genetic relationships of these two ethnic groups with other Bantu‐speaking populations. Moreover, by comparing our data with those from other Niger‐Congo speaking populations, we aim to clarify some aspects of evolutionary and demographic processes accompan…
Ethnogenomic diversity of Caucasus, Daghestan
Autosomal short‐tandem repeats (STRs) were typed in ethnic populations of Kubachians, Dargins, Avars, Lezgins, Kumiks, and Nogais of the Caucasus (Daghestan, Russia) at the University of Utah. Daghestan ethnic populations demonstrated differences in STR allele frequency distributions, but these differences were much lower among these ethnic groups compared to worldwide ethnic groups. The observed genetic diversity was low while F ST values were h…
Diversity drop and identity maintenance in the male gene-pool of corsican immigrants with Maghreb origin
Genetic History of the Population of Corsica (Western Mediterranean) as Inferred from Autosomal STR Analysis
To genetically reconstruct the demographic history of the human population of Corsica (western Mediterranean), we analyzed the variability at eight autosomal STR loci (FES, VWA, CSF1PO, TH01, F13A1, TPOX, CD4, and D3S1358) in a sample of 179 native blood donors from 4 out of the 5 administrative districts. The main line of genetic discontinuity inferred from the spatial distribution of STR variability overlapped the linguistic and geographic boun…
Peopling of three Mediterranean Islands (Corsica, Sardinia, and Sicily) inferred by Y‐chromosome biallelic variability
An informative set of biallelic polymorphisms was used to study the structure of Y‐chromosome variability in a sample from the Mediterranean islands of Corsica and Sicily, and compared with data on Sardinia to gain insights into the ethnogenesis of these island populations. The results were interpreted in a broader Mediterranean context by including in the analysis neighboring populations previously studied with the same methodology. All samples …
A Study of Y-Chromosome Microsatellite Variation in Sub-Saharan Africa: A Comparison between F ST and R ST Genetic Distances
Seven Y-chromosome microsatellite loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, and DYS393) were analyzed in three populations from sub-Saharan Africa: the Bamileke and Ewondo populations from Cameroon and the Hutu from Rwanda. Complete typing was obtained for 112 individuals, and a total of 53 different haplotypes was observed. The single-locus gene diversity, averaged across populations, ranges from 0.100 for the DYS392 locus to 0.610…
Variation at 10 protein coding loci in the mbenzele pygmies from the central african republic and a comparison with microsatellite data
Ten protein coding loci (6-PGD, A1-AT, ACP1, CaII, ESD, GC, GPX1, Hb beta, PGM1, and TF) were analyzed in the Mbenzele Pygmies from the Central African Republic. The frequency data were used to calculate the genetic distances between Mbenzele Pygmies and other African groups. In the principal coordinate plot of FST genetic distances, the Mbenzele cluster together with other Pygmies of the western cluster, the Biaka from C.A.R., Gielli from Camero…
Microsatellite variation in Central Africa: An analysis of intrapopulational and interpopulational genetic diversity
As a part of a research project on molecular variation in Central Africa, we have analyzed 10 microsatellites (CD4, CSFO, D3S1358, D18S51, D21S11, F13A1, FES, TH01, TPOX, and VWA) in the Bamileke and Ewondo from Cameroon and the Sanga and Mbenzele Pygmies from the Central African Republic (a total of 390 chromosomes). A statistically significant trend towards heterozygote deficiency was detected in the Mbenzele Pygmies. This was established throu…
Cytogenetic analysis shows extensive genomic rearrangements between red howler ( Alouatta seniculus, Linnaeus ) subspecies
A comparison of the G‐banded karyotypes of two red howler subspecies, Alouatta seniculus arctoidea and A. s. sara , showed that they differed by at least 14 chromosomal rearrangements. Genomic reshuffling is so great that homologs between subspecies could not be found for some chromosome, while the assignment of homology for other chromosomes remains uncertain. The two red howlers, however, share an unusual X 1 X 2 Y 1 Y 2 / X 1 X 1 X 2 X 2 sex‐c…
Genomic reorganization and disrupted chromosomal synteny in the siamang ( Hylobates syndactylus ) revealed by fluorescence in situ hybridization
We employed in situ hybridization (“chromosome painting”) of chromosome‐specific DNA libraries of all human chromosomes to establish homologies between the human and siamang karyotypes (Hylobates syndactylus, 2n = 50). Numerous intra‐ and interchromosomal rearrangements have led to a massive reorganization of the siamang karyotype. There have been a minimum of 33 translocations. The 24 siamang autosomes are composed of 60 recognizable segments th…
Paleoserology of the Christian population at Sayala (Lower Nubia): An evaluation of the reliability of the results
A paleoserological study of human remains from the Christian cemeteries of Sayala (Lower Nubia, 6th–11th centuries A. D.) was carried out by applying two techniques (absorption‐elution and haemagglutination‐inhibition), on two types of substratum (bones and hair), in separate laboratories (Pisa and Prague). The aim of research was to evaluate the degree of repeatability of the results and the reliability of the final paleoserological diagnoses. T…
A bio-cultural approach to the study of food choice: The contribution of taste genetics, population and culture
MtDNA variability in two Bantu‐speaking populations (Shona and Hutu) from Eastern Africa: Implications for peopling and migration patterns in sub‐Saharan Africa
In this study, we report novel data on mitochondrial DNA in two of the largest eastern Bantu‐speaking populations, the Shona from Zimbabwe and the Hutu from Rwanda. The goal is to evaluate the genetic relationships of these two ethnic groups with other Bantu‐speaking populations. Moreover, by comparing our data with those from other Niger‐Congo speaking populations, we aim to clarify some aspects of evolutionary and demographic processes accompan…
A Study of Y-Chromosome Microsatellite Variation in Sub-Saharan Africa: A Comparison between F ST and R ST Genetic Distances
Seven Y-chromosome microsatellite loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, and DYS393) were analyzed in three populations from sub-Saharan Africa: the Bamileke and Ewondo populations from Cameroon and the Hutu from Rwanda. Complete typing was obtained for 112 individuals, and a total of 53 different haplotypes was observed. The single-locus gene diversity, averaged across populations, ranges from 0.100 for the DYS392 locus to 0.610…
Paleoserology of the Christian population at Sayala (Lower Nubia): An evaluation of the reliability of the results
A paleoserological study of human remains from the Christian cemeteries of Sayala (Lower Nubia, 6th–11th centuries A. D.) was carried out by applying two techniques (absorption‐elution and haemagglutination‐inhibition), on two types of substratum (bones and hair), in separate laboratories (Pisa and Prague). The aim of research was to evaluate the degree of repeatability of the results and the reliability of the final paleoserological diagnoses. T…
Stuck in fragments: Population genetics of the Endangered collared brown lemur Eulemur collaris in the Malagasy littoral forest
OBJECTIVES: The Endangered collared brown lemur (Eulemur collaris) is the largest primate living in the littoral forest of southeastern Madagascar, a top priority habitat for biodiversity conservation on the island. Because this lemur is a key seed-disperser, an evaluation of the structure and connectivity of the populations surviving in the forest fragments is urgently needed to guide conservation plans. MATERIALS AND METHODS: Genetic variabilit…
Genomic reorganization and disrupted chromosomal synteny in the siamang ( Hylobates syndactylus ) revealed by fluorescence in situ hybridization
We employed in situ hybridization (“chromosome painting”) of chromosome‐specific DNA libraries of all human chromosomes to establish homologies between the human and siamang karyotypes (Hylobates syndactylus, 2n = 50). Numerous intra‐ and interchromosomal rearrangements have led to a massive reorganization of the siamang karyotype. There have been a minimum of 33 translocations. The 24 siamang autosomes are composed of 60 recognizable segments th…
Paleoserology of the Christian population at Sayala (Lower Nubia): An evaluation of the reliability of the results
A paleoserological study of human remains from the Christian cemeteries of Sayala (Lower Nubia, 6th–11th centuries A. D.) was carried out by applying two techniques (absorption‐elution and haemagglutination‐inhibition), on two types of substratum (bones and hair), in separate laboratories (Pisa and Prague). The aim of research was to evaluate the degree of repeatability of the results and the reliability of the final paleoserological diagnoses. T…
Cytogenetic analysis shows extensive genomic rearrangements between red howler ( Alouatta seniculus, Linnaeus ) subspecies
A comparison of the G‐banded karyotypes of two red howler subspecies, Alouatta seniculus arctoidea and A. s. sara , showed that they differed by at least 14 chromosomal rearrangements. Genomic reshuffling is so great that homologs between subspecies could not be found for some chromosome, while the assignment of homology for other chromosomes remains uncertain. The two red howlers, however, share an unusual X 1 X 2 Y 1 Y 2 / X 1 X 1 X 2 X 2 sex‐c…
Genomic reorganization and disrupted chromosomal synteny in the siamang ( Hylobates syndactylus ) revealed by fluorescence in situ hybridization
We employed in situ hybridization (“chromosome painting”) of chromosome‐specific DNA libraries of all human chromosomes to establish homologies between the human and siamang karyotypes (Hylobates syndactylus, 2n = 50). Numerous intra‐ and interchromosomal rearrangements have led to a massive reorganization of the siamang karyotype. There have been a minimum of 33 translocations. The 24 siamang autosomes are composed of 60 recognizable segments th…
Microsatellite variation in Central Africa: An analysis of intrapopulational and interpopulational genetic diversity
As a part of a research project on molecular variation in Central Africa, we have analyzed 10 microsatellites (CD4, CSFO, D3S1358, D18S51, D21S11, F13A1, FES, TH01, TPOX, and VWA) in the Bamileke and Ewondo from Cameroon and the Sanga and Mbenzele Pygmies from the Central African Republic (a total of 390 chromosomes). A statistically significant trend towards heterozygote deficiency was detected in the Mbenzele Pygmies. This was established throu…
Variation at 10 protein coding loci in the mbenzele pygmies from the central african republic and a comparison with microsatellite data
Ten protein coding loci (6-PGD, A1-AT, ACP1, CaII, ESD, GC, GPX1, Hb beta, PGM1, and TF) were analyzed in the Mbenzele Pygmies from the Central African Republic. The frequency data were used to calculate the genetic distances between Mbenzele Pygmies and other African groups. In the principal coordinate plot of FST genetic distances, the Mbenzele cluster together with other Pygmies of the western cluster, the Biaka from C.A.R., Gielli from Camero…
Peopling of three Mediterranean Islands (Corsica, Sardinia, and Sicily) inferred by Y‐chromosome biallelic variability
An informative set of biallelic polymorphisms was used to study the structure of Y‐chromosome variability in a sample from the Mediterranean islands of Corsica and Sicily, and compared with data on Sardinia to gain insights into the ethnogenesis of these island populations. The results were interpreted in a broader Mediterranean context by including in the analysis neighboring populations previously studied with the same methodology. All samples …
A Study of Y-Chromosome Microsatellite Variation in Sub-Saharan Africa: A Comparison between F ST and R ST Genetic Distances
Seven Y-chromosome microsatellite loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, and DYS393) were analyzed in three populations from sub-Saharan Africa: the Bamileke and Ewondo populations from Cameroon and the Hutu from Rwanda. Complete typing was obtained for 112 individuals, and a total of 53 different haplotypes was observed. The single-locus gene diversity, averaged across populations, ranges from 0.100 for the DYS392 locus to 0.610…
Genetic History of the Population of Corsica (Western Mediterranean) as Inferred from Autosomal STR Analysis
To genetically reconstruct the demographic history of the human population of Corsica (western Mediterranean), we analyzed the variability at eight autosomal STR loci (FES, VWA, CSF1PO, TH01, F13A1, TPOX, CD4, and D3S1358) in a sample of 179 native blood donors from 4 out of the 5 administrative districts. The main line of genetic discontinuity inferred from the spatial distribution of STR variability overlapped the linguistic and geographic boun…
Diversity drop and identity maintenance in the male gene-pool of corsican immigrants with Maghreb origin
Ethnogenomic diversity of Caucasus, Daghestan
Autosomal short‐tandem repeats (STRs) were typed in ethnic populations of Kubachians, Dargins, Avars, Lezgins, Kumiks, and Nogais of the Caucasus (Daghestan, Russia) at the University of Utah. Daghestan ethnic populations demonstrated differences in STR allele frequency distributions, but these differences were much lower among these ethnic groups compared to worldwide ethnic groups. The observed genetic diversity was low while F ST values were h…
MtDNA variability in two Bantu‐speaking populations (Shona and Hutu) from Eastern Africa: Implications for peopling and migration patterns in sub‐Saharan Africa
In this study, we report novel data on mitochondrial DNA in two of the largest eastern Bantu‐speaking populations, the Shona from Zimbabwe and the Hutu from Rwanda. The goal is to evaluate the genetic relationships of these two ethnic groups with other Bantu‐speaking populations. Moreover, by comparing our data with those from other Niger‐Congo speaking populations, we aim to clarify some aspects of evolutionary and demographic processes accompan…
The dual origin of tati‐speakers from dagestan as written in the genealogy of uniparental variants
The independent demographic histories of the two samples, with mutually reversed profiles at paternally and maternally transmitted genetic systems, suggest that geographic proximity and linguistic assimilation of Tati-speakers from Dagestan do not reflect a common ancestry
Increased efficiency in geographic ancestry assignment and human identification by combining lineage profiles: The case of the iranians
OBJECTIVES: This research is a first empirical attempt to quantify the increase of the among-groups variance and the probative value of a DNA evidence when combining profiles based on markers with uniparental inheritance. METHODS: Yfiler and HVS-I panels of loci were analyzed in 130 healthy unrelated males from six Iranian native groups. RESULTS: A separate analysis of DNA profiles at the two lineage markers failed to detect a population substruc…
A bio-cultural approach to the study of food choice: The contribution of taste genetics, population and culture
Stuck in fragments: Population genetics of the Endangered collared brown lemur Eulemur collaris in the Malagasy littoral forest
OBJECTIVES: The Endangered collared brown lemur (Eulemur collaris) is the largest primate living in the littoral forest of southeastern Madagascar, a top priority habitat for biodiversity conservation on the island. Because this lemur is a key seed-disperser, an evaluation of the structure and connectivity of the populations surviving in the forest fragments is urgently needed to guide conservation plans. MATERIALS AND METHODS: Genetic variabilit…
Biology (14 works) · Demography (11 works) · Population (11 works) · Evolutionary biology (10 works) · Forensic and Genetic Research (9 works) · Gene (9 works) · Genetics (9 works) · Geography (9 works) · Genetic diversity and population structure (8 works) · Allele (7 works)