Moses S Schanfield
Biographic Data
| ID | 4091424 |
|---|---|
| NAME | Moses S Schanfield |
| GIVEN NAMES | Moses S |
| FAMILY NAME | Schanfield |
| SIGNATURE | SCHANFIELD M S |
| AFFILIATIONS | American Red Cross |
| ORCID | 0000-0002-7128-1482 |
| VERIFIED | Yes |
| TOTAL WORKS | 14 |
| TOTAL CITATIONS | 8 |
| WORKS AS AUTHOR | 14 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1977 |
| LATEST PUBLICATION YEAR | 2015 |
| H-INDEX | 2 |
Epigenetic mechanisms as an archive of ancestral dietary history of populations
Immunoglobulin allotypes in Southwest Asia
Southwest Asia has a long history of contact with Central Asian and with Sub‐Saharan African populations. Is the genetic structure of these populations reflective of these historical facts? To study this, data was generated on the immunoglobulin heavy chain (GM) and light chain (KM) allotypes from seven Arab and three non‐Arab populations in SW Asia to examine the relationship of these populations to SE European, NW Indian, Sub‐Saharan African, a…
Applications of Pooled DNA Samples to the Assessment of Population Affinities
Pooled DNA samples have been used in association studies of Mendelian disease genes. This method involves combining equal quantities of DNA from patients and control subjects into separate pools and comparing the pools for distributions of genetic markers. In this study identical quantities of DNA from 300 individuals representing 6 populations were pooled and amplified for 296 loci using the touchdown polymerase chain reaction (PCR) method. The …
Immunoglobulin Allotypes among Taiwan Aborigines
The aborigines of Taiwan represent the indigenous inhabitants of the island at the time of the arrival of the Chinese from the mainland. Linguistically, the aboriginal Taiwanese are related to the Malayo-Polynesian-speaking inhabitants of Indonesia and the Philippines. Three tribes occupied lowland areas while six tribes occupied highland areas. Previous studies indicate that genetic markers associated with malaria occur in lowland populations. T…
Interpreting DNA evidence
Interpreting DNA evidence
Genetic admixture and gallbladder disease in Mexican Americans
Gallbladder disease is a common source of morbidity in the Mexican American population. Genetic heritage has been proposed as a possible contributor, but evidence for this is limited. Because gallbladder disease has been associated with Native American heritage, genetic admixture may serve as a useful proxy for genetic susceptibility to the disease in epidemiologic studies. The objective of our study was to examine the possibility that gallbladde…
Genetic admixture and gallbladder disease in Mexican Americans
Gallbladder disease is a common source of morbidity in the Mexican American population. Genetic heritage has been proposed as a possible contributor, but evidence for this is limited. Because gallbladder disease has been associated with Native American heritage, genetic admixture may serve as a useful proxy for genetic susceptibility to the disease in epidemiologic studies. The objective of our study was to examine the possibility that gallbladde…
DNA interpopulational variation in Siberian indigenous populations
Using mtDNA and classical markers, previous studies have found that the Altai are genetically divergent from the rest of Siberia. This study uses five variable number tandem repeat (VNTR) loci to examine the relationship of the Altai to other indigenous Siberian populations. Frequencies of VNTR fragments have been obtained from the DNA of 95 individuals living in the Altai village of Mendur-Sokkon. A Kolmogorov-Smirnov test shows that the Altai a…
Native American mitochondrial DNA analysis indicates that the Amerind and the Nadene populations were founded by two independent migrations.
Mitochondrial DNAs (mtDNAs) from 167 American Indians including 87 Amerind-speakers (Amerinds) and 80 Nadene-speakers (Nadene) were surveyed for sequence variation by detailed restriction analysis. All Native American mtDNAs clustered into one of four distinct lineages, defined by the restriction site variants: HincII site loss at np 13,259, AluI site loss at np 5,176, 9-base pair (9-bp) COII-tRNA(Lys) intergenic deletion and HaeIII site gain at …
Genetic variation at the immunoglobulin allotype loci in Creoles of Trinidad
The sera of a sample of 204 Croeoles from Trinidad were tested for the presence of polymorphic gene complexes occurring on immunoglobulin ligh‐ and heavy‐chain molecules including the allotypic markers IGKC 1, IGHA2 1 and 2, IGHG1 A, X, F, and Z, and IGHG3 G, G5, BO, B1, B3, B4, B5, C3, C5, S, and T. Nine IGHG (GM) haplotypes occur in polymorphic frequencies (>0.1) in this population, including known African, Asian, Caucasian, and Amerindian mark…
Immunoglobulin allotypes in Jewish populations living in Israel and the United States
The ongoing interest in the interrelationships of Jewish populations justifies inclusion of the immunoglobulin allotypes in an ethnohistorical analysis. A total of 2,184 serum specimens obtained from unrelated Israeli Jewish and self‐identified Milwaukee, WI, Jewish blood donors were classified as Ashkenazi, Sephardi, Asiatic, or North African and tested for G1m (a, x, z, and f), G3m (b0, b1, b3, b5, g), A2m (1 and 2), and Km (1). Selected sera w…
Admixture and Heterozygosity in West Alaskan Populations
Average heterozygosities for four communities (Savoonga and Gambell on St Lawrence Island, the King Island community now located in Nome, and Wales) are computed from blood allele frequencies. No significant relationship is found between this measure of heterozygosity and the amount of European admixture calculated from gamma globulin haplotype frequencies, indicating that forces other than European gene flow are affecting relative heterozygosity…
Population affinities of the Australian aborigines as reflected by the genetic markers of immunoglobulins
Population affinities of the Australian aborigines as reflected by the genetic markers of immunoglobulins
Immunoglobulin allotypes in Jewish populations living in Israel and the United States
The ongoing interest in the interrelationships of Jewish populations justifies inclusion of the immunoglobulin allotypes in an ethnohistorical analysis. A total of 2,184 serum specimens obtained from unrelated Israeli Jewish and self‐identified Milwaukee, WI, Jewish blood donors were classified as Ashkenazi, Sephardi, Asiatic, or North African and tested for G1m (a, x, z, and f), G3m (b0, b1, b3, b5, g), A2m (1 and 2), and Km (1). Selected sera w…
Immunoglobulin Allotypes among Taiwan Aborigines
The aborigines of Taiwan represent the indigenous inhabitants of the island at the time of the arrival of the Chinese from the mainland. Linguistically, the aboriginal Taiwanese are related to the Malayo-Polynesian-speaking inhabitants of Indonesia and the Philippines. Three tribes occupied lowland areas while six tribes occupied highland areas. Previous studies indicate that genetic markers associated with malaria occur in lowland populations. T…
Population affinities of the Australian aborigines as reflected by the genetic markers of immunoglobulins
Admixture and Heterozygosity in West Alaskan Populations
Average heterozygosities for four communities (Savoonga and Gambell on St Lawrence Island, the King Island community now located in Nome, and Wales) are computed from blood allele frequencies. No significant relationship is found between this measure of heterozygosity and the amount of European admixture calculated from gamma globulin haplotype frequencies, indicating that forces other than European gene flow are affecting relative heterozygosity…
Immunoglobulin allotypes in Jewish populations living in Israel and the United States
The ongoing interest in the interrelationships of Jewish populations justifies inclusion of the immunoglobulin allotypes in an ethnohistorical analysis. A total of 2,184 serum specimens obtained from unrelated Israeli Jewish and self‐identified Milwaukee, WI, Jewish blood donors were classified as Ashkenazi, Sephardi, Asiatic, or North African and tested for G1m (a, x, z, and f), G3m (b0, b1, b3, b5, g), A2m (1 and 2), and Km (1). Selected sera w…
Genetic variation at the immunoglobulin allotype loci in Creoles of Trinidad
The sera of a sample of 204 Croeoles from Trinidad were tested for the presence of polymorphic gene complexes occurring on immunoglobulin ligh‐ and heavy‐chain molecules including the allotypic markers IGKC 1, IGHA2 1 and 2, IGHG1 A, X, F, and Z, and IGHG3 G, G5, BO, B1, B3, B4, B5, C3, C5, S, and T. Nine IGHG (GM) haplotypes occur in polymorphic frequencies (>0.1) in this population, including known African, Asian, Caucasian, and Amerindian mark…
Native American mitochondrial DNA analysis indicates that the Amerind and the Nadene populations were founded by two independent migrations.
Mitochondrial DNAs (mtDNAs) from 167 American Indians including 87 Amerind-speakers (Amerinds) and 80 Nadene-speakers (Nadene) were surveyed for sequence variation by detailed restriction analysis. All Native American mtDNAs clustered into one of four distinct lineages, defined by the restriction site variants: HincII site loss at np 13,259, AluI site loss at np 5,176, 9-base pair (9-bp) COII-tRNA(Lys) intergenic deletion and HaeIII site gain at …
DNA interpopulational variation in Siberian indigenous populations
Using mtDNA and classical markers, previous studies have found that the Altai are genetically divergent from the rest of Siberia. This study uses five variable number tandem repeat (VNTR) loci to examine the relationship of the Altai to other indigenous Siberian populations. Frequencies of VNTR fragments have been obtained from the DNA of 95 individuals living in the Altai village of Mendur-Sokkon. A Kolmogorov-Smirnov test shows that the Altai a…
Genetic admixture and gallbladder disease in Mexican Americans
Gallbladder disease is a common source of morbidity in the Mexican American population. Genetic heritage has been proposed as a possible contributor, but evidence for this is limited. Because gallbladder disease has been associated with Native American heritage, genetic admixture may serve as a useful proxy for genetic susceptibility to the disease in epidemiologic studies. The objective of our study was to examine the possibility that gallbladde…
Genetic admixture and gallbladder disease in Mexican Americans
Gallbladder disease is a common source of morbidity in the Mexican American population. Genetic heritage has been proposed as a possible contributor, but evidence for this is limited. Because gallbladder disease has been associated with Native American heritage, genetic admixture may serve as a useful proxy for genetic susceptibility to the disease in epidemiologic studies. The objective of our study was to examine the possibility that gallbladde…
Interpreting DNA evidence
Interpreting DNA evidence
Immunoglobulin Allotypes among Taiwan Aborigines
The aborigines of Taiwan represent the indigenous inhabitants of the island at the time of the arrival of the Chinese from the mainland. Linguistically, the aboriginal Taiwanese are related to the Malayo-Polynesian-speaking inhabitants of Indonesia and the Philippines. Three tribes occupied lowland areas while six tribes occupied highland areas. Previous studies indicate that genetic markers associated with malaria occur in lowland populations. T…
Applications of Pooled DNA Samples to the Assessment of Population Affinities
Pooled DNA samples have been used in association studies of Mendelian disease genes. This method involves combining equal quantities of DNA from patients and control subjects into separate pools and comparing the pools for distributions of genetic markers. In this study identical quantities of DNA from 300 individuals representing 6 populations were pooled and amplified for 296 loci using the touchdown polymerase chain reaction (PCR) method. The …
Immunoglobulin allotypes in Southwest Asia
Southwest Asia has a long history of contact with Central Asian and with Sub‐Saharan African populations. Is the genetic structure of these populations reflective of these historical facts? To study this, data was generated on the immunoglobulin heavy chain (GM) and light chain (KM) allotypes from seven Arab and three non‐Arab populations in SW Asia to examine the relationship of these populations to SE European, NW Indian, Sub‐Saharan African, a…
Epigenetic mechanisms as an archive of ancestral dietary history of populations
Biology (14 works) · Demography (10 works) · Population (10 works) · Gene (9 works) · Forensic and Genetic Research (8 works) · Genetics (7 works) · Genetics (6 works) · Evolutionary biology (5 works) · Geography (5 works) · Allele (4 works)