John W Mason
Biographic Data
| ID | 4095546 |
|---|---|
| NAME | John W Mason |
| GIVEN NAMES | John W |
| FAMILY NAME | Mason |
| SIGNATURE | MASON J W |
| VERIFIED | No |
| TOTAL WORKS | 37 |
| TOTAL CITATIONS | 6 |
| AUTHOR COUNT | 37 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1961 |
| LATEST PUBLICATION YEAR | 2002 |
| H-INDEX | 1 |
The Cold War
Mason provides concise coverage of the entire Cold War, paying particular attention to the Soviet-American dimension. This pamphlet:* Analyzes the origins of the conflict* Examines how the existence of nuclear weapons gives a unique character to the period* Discusses the involvement of other nations and regions, particularly China* Explains how and why the cold war ended* Draws on recent research of revisionist scholars.
Marked Lability in Urinary Cortisol Levels in Subgroups of Combat Veterans With Posttraumatic Stress Disorder During an Intensive Exposure Treatment Program
OBJECTIVE: The objective of this study was to obtain longitudinal data on lability of cortisol levels in posttraumatic stress disorder (PTSD) because previous studies have largely been based on sampling at a single time point and have yielded varying results. METHODS: This study measured urinary cortisol levels at admission, midcourse, and discharge during a 90-day hospitalization period in male Vietnam combat veterans with PTSD (N = 51). RESULTS…
Psychogenic Lowering of Urinary Cortisol Levels Linked to Increased Emotional Numbing and a Shame-Depressive Syndrome in Combat-Related Posttraumatic Stress Disorder
OBJECTIVE: The purpose of the study was to search for the intrapsychic correlates of individual differences in cortisol levels in male Vietnam combat veterans with posttraumatic stress disorder. METHODS: The study involved measurement of urinary cortisol levels and clinical assessment with a broad profile of psychometric tests during a single 48-hour period in 30 inpatients. RESULTS: The main finding by both correlation and t test analyses was a …
Stages of decompensation in combat-related posttraumatic stress disorder
Political Economy and the Response to Socialism in Britain, 1870–1914
Political economy suffered a sharp decline in prestige and influence in Britain after 1870. The methods, doctrines and policies of the classical school were called into question by a younger generation of economists, eager to respond positively to the sudden appearance of the ‘ social problem’ in politics. The most dramatic break with the old school took place in the sphere of policy, where the link between laissez-faire and political economy was…
Plasma Cortisol and Norepinephrine Responses in Anticipation of Muscular Exercise
Strikingly consistent individual responses and significant mean elevations of plasma cortisol levels (5 to 9 μ g%) and plasma norepinephrine levels (2.0 to 2.5 μ g/1) were observed during a 20-min interval prior to onset of the first exhausting exercise (70% max VO2) session in eight normal young men. No detectable plasma epinephrine response was observed. Such consistent anticipatory psychoendocrine responses were not found prior to subsequent e…
Thyroid (Plasma BEI) Response to Chair Restraint in the Monkey
Study of a series of 26 rhesus monkeys revealed significant elevations of plasma butanol extractable iodine (BEI) levels persisting through a 6-day period of chair restraint. There was a mean BEI increase from a control baseline of 3.2 μg% to a peak of 5.1 μg% on the third day of chair restraint. Study of 14 of these monkeys throughout a longer period of 8 weeks of chair restraint indicated that, although duration of response varied considerably …
A Psychoendocrine Study of Bereavement
This study reports 17-hydroxycorticosteroid excretion rates of 40 parents during the 2 years following the death of their children from leukemia. Overall group mean rates remained unchanged, but this apparent stability was the result of an interaction between individuals with low rates during the child's illness, who significantly increased their rates at follow-up return visits to NIH, and those with high values pre-loss, who showed a significan…
A Psychoendocrine Study of Bereavement
This paper reports psychologic observations on previously studied parents of leukemic children during the period of bereavement. Thirty-six parents returned to the hospital after 6 months and 21 returned at 2 years after their child's death for interviewing and urine collections. Extensive notes on structured interviews made without knowledge of the biochemical data revealed reliable differences between those parents in the highest quartile of ad…
Multiple Determinants of 17-Hydroxycorticosteroid Excretion in Recruits During Basic Training
To define the effect of psychologic and other variables on 17-hydroxycorticosteroid excretion, a mean 17-OHCS level was obtained for each of 46 basic trainees, plus a rating of how effectively each was coping with psychologic stress, based on interviews and observations. Psychologic ratings and weight both correlated with 17-OHCS and together predicted 17-OHCS more accurately than did either alone. Several MMPI scales correlated with 17-OHCS; an …
Strategy in Psychosomatic Research
From the Department oi Neuroendocrinology, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, DC. Presidential Address, Annual Meeting of the American Psychosomatic Society, March 21, 1970. Received for publication April 10, 1970. Address for reprint requests: Dr. J. Mason, Department of Neuroendocrinology, Walter Reed Army Institute of Research, Washington, DC 20012
Androgen Responses to Stress
Recruits in the first month of basic training at Fort Dix, NJ and special forces personnel anticipating imminent combat in Vietnam showed lowered excretion of testosterone, epitestosterone, androsterone, and etiocholanolone. This suggests that men responded to the potential threat of these situations with an inhibition of testosterone secretion. The wide range of values, similar to that observed for 17-OHCS excretion, reflects the importance of i…
Thyroid (Plasma Butanol-Extractable Iodine) Responses to 72-Hr. Avoidance Sessions in the Monkey
Plasma thyroid hormone levels, as judged by the BEI measurement, show slow but prolonged elevations in association with conditioned avoidance sessions in the monkey. The peak of the mean BEI response occurs at the end of the 3-day avoidance session and represents about a 50% elevation above baseline values. Levels remained elevated well into the recovery period and the response was prolonged as much as 2 or 3 weeks in some experiments. Smaller, b…
Plasma Insulin Response to 72-Hr. Avoidance Sessions in the Monkey
Plasma immunoreactive insulin levels, determined by radioimmunoassay, show a biphasic pattern of response to avoidance sessions in the monkey. There is an initial drop in plasma immunoreactive insulin levels during the first hours of avoidance and a later prolonged elevation of levels above baseline--persisting often for many days following 72-hr. avoidance sessions. The fact that the plasma insulin changes in avoidance do not appear to be mediat…
Urinary Testosterone Response to 72-Hr. Avoidance Sessions in the Monkey
Urinary testosterone levels show a biphasic response in association with 72hr. avoidance sessions in the monkey, characterized by an initial decline during avoidance followed by a rebound elevation during the recovery period. The duration of the two response phases, the primary lowering and the secondary elevation, may vary from one experiment to the next, but the general configuration of the response curve remains the same. Similar testosterone …
Organization of the Multiple Endocrine Responses to Avoidance in the Monkey
In the presentation of an interpretation of the findings in the present study a number of general issues have been discussed. The findings suggest that the scope of psychoendocrine responses is remarkably broad. The findings also suggest that the multiple hormonal responses to avoidance are organized on an over-all basis. Some specific characteristics of this organization were suggested. The possibility that the multiple psychoendocrine responses…
“Over-all” Hormonal Balance as a Key to Endocrine Organization
Department of Neuroendocrinology, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D. C
Urinary Aldosterone and Urine Volume Responses to 72-Hr. Avoidance Sessions in the Monkey
Urinary aldosterone levels showed marked fluctuations in relation to 72-hr. conditioned avoidance sessions in the monkey. Two different response patterns were observed. The first was a biphasic response characterized by an initial depression during avoidance, followed by a rebound elevation during the recovery period. The second was characterized by an elevation, in some cases quite marked, during avoidance with a return to basal level during the…
A Review of Psychoendocrine Research on the Pituitary-Thyroid System
At first glance, the present status of psychoendocrine research on the pituitary-thyroid system may appear somewhat confusing. Yet if certain methodological issues are considered critically, the field may not be so unsettled as it first appears. It is perhaps particularly illuminating to view this work in the perspective of the more advanced but similar psychoendocrine research on the adrenal systems. If this is done, several conspicious deficien…
A Review of Psychoendocrine Research on the Pituitary-Adrenal Cortical System
Massive evidence has now accumulated which indicates that the pituitary-adrenal cortical system responds sensitively to psychological influences. This evidence represents converging and reinforcing findings from diverse studies of many species, including man. It involved the use of many methods of eliciting, isolating, and evaluating emotional disturbances, relatively direct and specific biochemical measurements of endocrine activity, and control…
The Scope of Psychoendocrine Research
Department of Neuroendocrinology, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D. C. 20012
Urinary Estrone, Estradiol, and Estriol Responses to 72-Hr. Avoidance Sessions in the Monkey
Urinary estrone, estradiol and estriol all show a similar biphasic response to 72-hr. conditioned avoidance sessions in the monkey, characterized by a decline in levels during avoidance, usually followed by a rebound elevation in the recovery period. The duration of the two response phases, the primary depression and the secondary elevation, may vary from one experiment to the next, particularly in relation to repetition of the stressful experien…
Urinary Androsterone, Etiocholanolone, and Dehydroepiandrosterone Responses to 72-Hr. Avoidance Sessions in the Monkey
Urinary androsterone, etiocholanolone, and dehydroepiandrosterone levels show substantial responses in association with 72-hr. avoidance sessions in the monkey. In most instances a biphasic response is observed which is characterized by a decline in levels during avoidance followed by a rebound elevation during the recovery period. The duration of the two response phases, the primary depression and the secondary elevation, may vary from one exper…
Urinary Epinephrine and Norepinephrine Responses to 72-Hr. Avoidance Sessions in the Monkey
Marked elevations in urinary epinephrine levels occur in response to 72-hr. conditioned avoidance sessions in the monkey. The response is relatively rapid and brief, reaching a peak on the first avoidance day, declining on the second and third avoidance days, and returning to baseline levels immediately on the first recovery day. In some instances epinephrine levels fell substantially below baseline values during the recovery period. Smaller but …
Plasma Growth Hormone Response to Avoidance Sessions in the Monkey
Plasma immunoreactive growth hormone levels usually rise during conditioned avoidance sessions in monkeys. The rise occurs promptly, being evident in the first sample obtained after avoidance onset (30 min.), and levels remain elevated during 2-hr. avoidance sessions. Preliminary experiments suggest that the elevations may persist during longer avoidance sessions, but the reliability of single 9: 00 A.M. fasting samples in assessing day-to-day ch…
Political Economy and the Response to Socialism in Britain, 1870–1914
Political economy suffered a sharp decline in prestige and influence in Britain after 1870. The methods, doctrines and policies of the classical school were called into question by a younger generation of economists, eager to respond positively to the sudden appearance of the ‘ social problem’ in politics. The most dramatic break with the old school took place in the sphere of policy, where the link between laissez-faire and political economy was…
Stages of decompensation in combat-related posttraumatic stress disorder
Concurrent Plasma Epinephrine, Norepinephrine and 17-Hydroxycorticosteroid Levels During Conditioned Emotional Disturbances in Monkeys
In studies involving biochemical measurement of plasma 17-OH-CS, norepinephrine, and epinephrine levels during conditioned emotional disturbances in monkeys, elevations in 17-OH-CS and norepinephrine levels were observed in a variety of experimental situations. The regulation of epinephrine secretion, however, appeared to have a more selective basis. In relatively stereotyped, predictable situations such as avoidance and CER, patterns of 17-OH-CS…
Psychological Factors Lowering Plasma 17-Hydroxycorticosteroid Concentration
While much recent evidence indicates that a variety of psychological stimulus conditions can elevate the circulating levels of hormones known to be responsive to stress, little work has been done exploring those conditions which might lower the levels of such hormones. Using 19 normal young adult male subjects viewing Disney nature-study films, it was discovered that the levels of plasma 17-hydroxycorticosteroid (17-OHCS) were lowered to a signif…
Urinary 17-Hydroxycorticosteroid Levels in Parents of Children with Neoplastic Disease
Urinary 17-hydroxycorticosteroid (17-OHCS) excretion rates were determined in 43 subjects, representing one or both parents of 26 children with neoplastic disease. Twentynine of the parents were admitted for study to a National Institute of Mental Health ward while their children were hospitalized; 14 parents lived at home and were studied on an “outpatient” basis. In this situation of chronic psychological stress, repeated determinations on each…
The Physiology of Emotions
Psychoendocrine Aspects of Acute Schizophrenic Reactions
Four young male soldiers suffering from first-episode acute schizophrenic reactions were studied psychiatrically and endocrinologically over a period of months while they received milieu therapy for their illnesses. Independent of endocrine findings, the clinical course of each patient was classified into phases, in which special emphasis was given to periods designated “Acute Psychotic Turmoil,” “Psychotic Equilibrium”, “Anaclitic Depression,” a…
Relationship Between Psychological Defenses and Mean Urinary 17-Hydroxycorticosteroid Excretion Rates
Thirty-one parents of children suffering from fatal illnesses were studied psychologically. Urinary 17-hydroxycorticosteroid (17-OHCS) levels were measured concurrently. Throughout the extended crisis, these parents had characteristic mean 17-OHCS excretion rates along the continuum from high to low excretion. The hypothesis was tested that the more effectively a parent defends against the threat of loss, the lower will be his mean 17-OHCS excret…
Relationship Between Psychological Defenses and Mean Urinary 17-Hydroxycorticosteroid Excretion Rates
The previous paper reported that it was possible to predict the mean urinary 17-hydroxycorticosteroid (17-OHCS) excretion rates of parents of fatally ill children on the basis of an evaluation of the effectiveness of their defenses. This report presents in detail the methods used to make predictions. The criteria of effective defense and the interviewing methods are described, and the process of predicting and the problems related to it are discu…
Corticosteroid Excretion in Normal Young Adults Living Under “Basal” Conditions
Under basal conditions in a hospital setting, mean 17-OHCS excretion for normal 18- to 25-year-old males and females was 8.5 (13.3–5.5) and 5.1 mg./day (8.6–3.0), respectively. Weight “correction” did not abolish this significant sex difference; it did alter somewhat the rank-order of “high” to “low” 17-OHCS excretors. Values for males were about 50% higher than those reported in outpatient studies. Subjects tended to be relatively consistent in …
Correlations Between Behavioral Variables and Urinary 17-Hydroxycorticosteroids in Depressed Patients
This paper presents a study of the relationship of urinary 17-hydroxycorticosteroids (17-OHCS) to behavioral variables in depressed patients. Longitudinal behavioral ratings of depression and anxiety showed high positive correlations with 17-OHCS levels when analyzed over time for a given patient. However, if mean depression ratings and mean 17-OHCS levels were taken for each of the 17 patients studied, a significant positive correlation was not …
Influence of the Hypnotic Trance on Plasma 17-Hydroxycorticosteroid Concentration
In a pilot study and a formal experiment, plasma 17-hydroxycorticosteroid concentration was observed to drop to unusually low levels (3 μg./100 ml. or less) at the end of 90 min. of deep, relaxing, hypnotic trance. In the formal experiment on 12 subjects who were very susceptible to hypnosis, the low plasma 17-OHCS levels occurred in 25% of the hypnotic sessions, but only rarely in control periods (p < .0001). This trance-associated phenomenon co…
Thyroid (Plasma Butanol-Extractable Iodine) Responses to 72-Hr. Avoidance Sessions in the Monkey
Plasma thyroid hormone levels, as judged by the BEI measurement, show slow but prolonged elevations in association with conditioned avoidance sessions in the monkey. The peak of the mean BEI response occurs at the end of the 3-day avoidance session and represents about a 50% elevation above baseline values. Levels remained elevated well into the recovery period and the response was prolonged as much as 2 or 3 weeks in some experiments. Smaller, b…
Plasma Insulin Response to 72-Hr. Avoidance Sessions in the Monkey
Plasma immunoreactive insulin levels, determined by radioimmunoassay, show a biphasic pattern of response to avoidance sessions in the monkey. There is an initial drop in plasma immunoreactive insulin levels during the first hours of avoidance and a later prolonged elevation of levels above baseline--persisting often for many days following 72-hr. avoidance sessions. The fact that the plasma insulin changes in avoidance do not appear to be mediat…
Urinary Testosterone Response to 72-Hr. Avoidance Sessions in the Monkey
Urinary testosterone levels show a biphasic response in association with 72hr. avoidance sessions in the monkey, characterized by an initial decline during avoidance followed by a rebound elevation during the recovery period. The duration of the two response phases, the primary lowering and the secondary elevation, may vary from one experiment to the next, but the general configuration of the response curve remains the same. Similar testosterone …
Organization of the Multiple Endocrine Responses to Avoidance in the Monkey
In the presentation of an interpretation of the findings in the present study a number of general issues have been discussed. The findings suggest that the scope of psychoendocrine responses is remarkably broad. The findings also suggest that the multiple hormonal responses to avoidance are organized on an over-all basis. Some specific characteristics of this organization were suggested. The possibility that the multiple psychoendocrine responses…
“Over-all” Hormonal Balance as a Key to Endocrine Organization
Department of Neuroendocrinology, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D. C
Urinary Aldosterone and Urine Volume Responses to 72-Hr. Avoidance Sessions in the Monkey
Urinary aldosterone levels showed marked fluctuations in relation to 72-hr. conditioned avoidance sessions in the monkey. Two different response patterns were observed. The first was a biphasic response characterized by an initial depression during avoidance, followed by a rebound elevation during the recovery period. The second was characterized by an elevation, in some cases quite marked, during avoidance with a return to basal level during the…
A Review of Psychoendocrine Research on the Pituitary-Thyroid System
At first glance, the present status of psychoendocrine research on the pituitary-thyroid system may appear somewhat confusing. Yet if certain methodological issues are considered critically, the field may not be so unsettled as it first appears. It is perhaps particularly illuminating to view this work in the perspective of the more advanced but similar psychoendocrine research on the adrenal systems. If this is done, several conspicious deficien…
A Review of Psychoendocrine Research on the Pituitary-Adrenal Cortical System
Massive evidence has now accumulated which indicates that the pituitary-adrenal cortical system responds sensitively to psychological influences. This evidence represents converging and reinforcing findings from diverse studies of many species, including man. It involved the use of many methods of eliciting, isolating, and evaluating emotional disturbances, relatively direct and specific biochemical measurements of endocrine activity, and control…
The Scope of Psychoendocrine Research
Department of Neuroendocrinology, Walter Reed Army Institute of Research, Walter Reed Army Medical Center, Washington, D. C. 20012
Urinary Estrone, Estradiol, and Estriol Responses to 72-Hr. Avoidance Sessions in the Monkey
Urinary estrone, estradiol and estriol all show a similar biphasic response to 72-hr. conditioned avoidance sessions in the monkey, characterized by a decline in levels during avoidance, usually followed by a rebound elevation in the recovery period. The duration of the two response phases, the primary depression and the secondary elevation, may vary from one experiment to the next, particularly in relation to repetition of the stressful experien…
Urinary Androsterone, Etiocholanolone, and Dehydroepiandrosterone Responses to 72-Hr. Avoidance Sessions in the Monkey
Urinary androsterone, etiocholanolone, and dehydroepiandrosterone levels show substantial responses in association with 72-hr. avoidance sessions in the monkey. In most instances a biphasic response is observed which is characterized by a decline in levels during avoidance followed by a rebound elevation during the recovery period. The duration of the two response phases, the primary depression and the secondary elevation, may vary from one exper…
Urinary Epinephrine and Norepinephrine Responses to 72-Hr. Avoidance Sessions in the Monkey
Marked elevations in urinary epinephrine levels occur in response to 72-hr. conditioned avoidance sessions in the monkey. The response is relatively rapid and brief, reaching a peak on the first avoidance day, declining on the second and third avoidance days, and returning to baseline levels immediately on the first recovery day. In some instances epinephrine levels fell substantially below baseline values during the recovery period. Smaller but …
Plasma Growth Hormone Response to Avoidance Sessions in the Monkey
Plasma immunoreactive growth hormone levels usually rise during conditioned avoidance sessions in monkeys. The rise occurs promptly, being evident in the first sample obtained after avoidance onset (30 min.), and levels remain elevated during 2-hr. avoidance sessions. Preliminary experiments suggest that the elevations may persist during longer avoidance sessions, but the reliability of single 9: 00 A.M. fasting samples in assessing day-to-day ch…
A Review of Psychoendocrine Research on the Sympathetic-Adrenal Medullary System
There appears now to be no reasonable doubt that both epinephrine and norepinephrine belong to the category of hormones which are responsive to psychological influences. Catecholamine levels, furthermore, appear sensitively to reflect relatively common, psychological reactions associated with “everyday” events, tasks, and activities. As in the case of the pituitary-adrenal cortical system, it appears that the central nervous system may exert an o…
Plasma and Urinary 17-Hydroxycorticosteroid Responses to 72-Hr. Avoidance Sessions in the Monkey
Marked elevations in both mean urinary and mean 9 A.M. plasma 17-OHCS levels are associated with 72-hr. avoidance sessions in the monkey. The urinary 17-OHCS elevations persist also for several days in the recovery period. The 17-OHCS elevations, while substantial, do not appear to represent maximal adrenal cortical responses and no evidence of adrenal cortical exhaustion was observed. Indirect evidence suggests rather the hypothesis that neural …
Medicine (33 works) · Psychology (31 works) · Internal Medicine (27 works) · Internal Medicine (27 works) · Stress Responses and Cortisol (24 works) · Endocrinology (21 works) · Endocrinology (21 works) · Hormone (13 works) · Clinical Psychology (11 works) · Physiology (9 works)