Pablo López
Biographic Data
| ID | 4149411 |
|---|---|
| NAME | Pablo López |
| GIVEN NAMES | Pablo |
| FAMILY NAME | López |
| SIGNATURE | LÓPEZ P |
| AFFILIATIONS | Ponce Health Sciences University |
| ORCID | 0000-0003-4857-8138 |
| VERIFIED | Yes |
| TOTAL WORKS | 14 |
| TOTAL CITATIONS | 8 |
| WORKS AS AUTHOR | 14 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2013 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 2 |
Building multi-sectoral alliances to co-design and pilot a gender-transformative comprehensive sexuality education intervention for adolescents
Stressors and Impact of the Covid-19 Pandemic on Vulnerable Hispanic Caregivers and Children
Psychological sequelae are important elements of the burden of disease among caregivers. Recognition of the impact of adversity and stress biomarkers is important to prevent mental health problems that affect rearing practices and child well-being. This cross-sectional study explored social determinants of health (SDoH)-mediated stressors during COVID-19 and risks for mental health problems among caregivers of children with prenatal Zika virus ex…
Genomic Surveillance of Sars-CoV-2 Variants in the Dominican Republic and Emergence of a Local Lineage
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an RNA virus that evolves over time, leading to new variants. In the current study, we assessed the genomic epidemiology of SARS-CoV-2 in the Dominican Republic. A total of 1149 SARS-CoV-2 complete genome nucleotide sequences from samples collected between March 2020 and mid-February 2022 in the Dominican Republic were obtained from the Global Initiative on Sharing All Influenza Data…
Un día en la vida de docente y estudiante virtual
En este trabajo presentamos un análisis de narraciones elaboradas por un grupo de residentes de dos profesorados universitarios de Argentina durante el primer semestre de 2020. Como equipo a cargo de las Prácticas Docentes nos posicionamos político-pedagógicamente desde la Educación Popular Latinoamericana, apuntando a la formación de profesionales reflexivos/as, que puedan desarrollar una mirada crítica. En los inicios del periodo de aislamiento…
Short Communication
The HIV-1 integrase viral protein is responsible for incorporating the viral DNA into the genomic DNA. The inhibition of viral integration into host cell DNA is part of recent therapeutic procedures. Combination therapy with protease and reverse transcriptase inhibitors has demonstrated good synergistic results in reducing viral replication. The purpose of this study is to assess the occurrence of integrase drug resistance mutations from the peri…
The generation of new tsunami risk areas due to an intentionally biased reconstruction process
Tsunamis are among the most significant hazards in coastal settlements. Mitigation measures have been focused mainly on physical aspects, and few studies have addressed vulnerability and resilience in a multidimensional approach. The main objective of the present work is to assess changes in vulnerability and, consequently, risk, considering a time-space dimension. Three deterministic tsunami scenarios based on historical events were analyzed, an…
A sustainability index for anthropized and urbanized coasts
Inflammatory Biomarkers, Microbiome, Depression, and Executive Dysfunction in Alcohol Users
Alcohol-related disorders (ARD) are highly prevalent among Latin American-Caribbean countries. Mental disorders are common comorbidities in individuals with ARD. However, the etiology of the association between ARD and mental disorders remains unclear. We examined the association of inflammatory cytokines, microbiome, and other biomakers with measures of depression, social anxiety, and executive functions. We observed a significant increase in cy…
Testing Broken Windows Theory in Mexico City
Objectives To test the broken windows theory in the Mexican context. Methods Publicly available homicide counts and census data at the neighborhood level were used. Broken windows theory was operationalized through the use of social disorder and physical disorder measures. Measures were both calculated using PCA. For data analysis, we employed four multilevel random intercept models to relate homicide counts to our broken windows components. Resu…
Regional Variations in Physical Fitness and Activity in Healthy and Overweight Ecuadorian Adolescents
Background: Insufficient physical activity (PA) and excessive sedentary behavior (SB) are the main contributors to adolescent obesity. However, it is uncertain whether recent economic growth and urbanization in Ecuador are contributing to an obesogenic environment. This study assessed the relationships among fitness, PA, SB, and perceived social support for PA in adolescents from urban (Quito) and rural (Loja) Ecuador. Methods: Fitness was estima…
Sanger and Next Generation Sequencing Approaches to Evaluate HIV-1 Virus in Blood Compartments
The implementation of antiretroviral treatment combined with the monitoring of drug resistance mutations improves the quality of life of HIV-1 positive patients. The drug resistance mutation patterns and viral genotypes are currently analyzed by DNA sequencing of the virus in the plasma of patients. However, the virus compartmentalizes, and different T cell subsets may harbor distinct viral subsets. In this study, we compared the patterns of HIV …
Cigarette Smoking Modulation of Saliva Microbial Composition and Cytokine Levels
Tobacco use has been implicated as an immunomodulator in the oral cavity and contributes to the development of oral cancer. In the present study, we investigated the effects of cigarette smoking on bacterial diversity and host responses compared to healthy nonsmoking controls. Saliva samples were collected from eighteen smokers and sixteen nonsmoking individuals by passive drool. The 16S rRNA gene was used to characterize the salivary microbiome …
The Genetic Diversity and Evolution of HIV-1 Subtype B Epidemic in Puerto Rico
HIV-1 epidemics in Caribbean countries, including Puerto Rico, have been reported to be almost exclusively associated with the subtype B virus (HIV-1B). However, while HIV infections associated with other clades have been only sporadically reported, no organized data exist to accurately assess the prevalence of non-subtype B HIV-1 infection. We analyzed the nucleotide sequence data of the HIV pol gene associated with HIV isolates from Puerto Rica…
Fundamentos epistemológicos del liderazgo distribuido
El artículo revisa investigaciones entre los años 1999 y 2013 con el objetivo de conocer las bases epistemológicas de la investigación en liderazgo distribuido, con especial interés en estudios de educación. Se concluye que es un campo en formación, con potencial, pero que sus bases empíricas son débiles y sus estrategias metodológicas no siempre están explícitas, lo que dificulta un poco evaluar sus descubrimientos. Con respecto a las bases teór…
Testing Broken Windows Theory in Mexico City
Objectives To test the broken windows theory in the Mexican context. Methods Publicly available homicide counts and census data at the neighborhood level were used. Broken windows theory was operationalized through the use of social disorder and physical disorder measures. Measures were both calculated using PCA. For data analysis, we employed four multilevel random intercept models to relate homicide counts to our broken windows components. Resu…
Fundamentos epistemológicos del liderazgo distribuido
El artículo revisa investigaciones entre los años 1999 y 2013 con el objetivo de conocer las bases epistemológicas de la investigación en liderazgo distribuido, con especial interés en estudios de educación. Se concluye que es un campo en formación, con potencial, pero que sus bases empíricas son débiles y sus estrategias metodológicas no siempre están explícitas, lo que dificulta un poco evaluar sus descubrimientos. Con respecto a las bases teór…
Fundamentos epistemológicos del liderazgo distribuido
El artículo revisa investigaciones entre los años 1999 y 2013 con el objetivo de conocer las bases epistemológicas de la investigación en liderazgo distribuido, con especial interés en estudios de educación. Se concluye que es un campo en formación, con potencial, pero que sus bases empíricas son débiles y sus estrategias metodológicas no siempre están explícitas, lo que dificulta un poco evaluar sus descubrimientos. Con respecto a las bases teór…
The Genetic Diversity and Evolution of HIV-1 Subtype B Epidemic in Puerto Rico
HIV-1 epidemics in Caribbean countries, including Puerto Rico, have been reported to be almost exclusively associated with the subtype B virus (HIV-1B). However, while HIV infections associated with other clades have been only sporadically reported, no organized data exist to accurately assess the prevalence of non-subtype B HIV-1 infection. We analyzed the nucleotide sequence data of the HIV pol gene associated with HIV isolates from Puerto Rica…
Regional Variations in Physical Fitness and Activity in Healthy and Overweight Ecuadorian Adolescents
Background: Insufficient physical activity (PA) and excessive sedentary behavior (SB) are the main contributors to adolescent obesity. However, it is uncertain whether recent economic growth and urbanization in Ecuador are contributing to an obesogenic environment. This study assessed the relationships among fitness, PA, SB, and perceived social support for PA in adolescents from urban (Quito) and rural (Loja) Ecuador. Methods: Fitness was estima…
Sanger and Next Generation Sequencing Approaches to Evaluate HIV-1 Virus in Blood Compartments
The implementation of antiretroviral treatment combined with the monitoring of drug resistance mutations improves the quality of life of HIV-1 positive patients. The drug resistance mutation patterns and viral genotypes are currently analyzed by DNA sequencing of the virus in the plasma of patients. However, the virus compartmentalizes, and different T cell subsets may harbor distinct viral subsets. In this study, we compared the patterns of HIV …
Cigarette Smoking Modulation of Saliva Microbial Composition and Cytokine Levels
Tobacco use has been implicated as an immunomodulator in the oral cavity and contributes to the development of oral cancer. In the present study, we investigated the effects of cigarette smoking on bacterial diversity and host responses compared to healthy nonsmoking controls. Saliva samples were collected from eighteen smokers and sixteen nonsmoking individuals by passive drool. The 16S rRNA gene was used to characterize the salivary microbiome …
The generation of new tsunami risk areas due to an intentionally biased reconstruction process
Tsunamis are among the most significant hazards in coastal settlements. Mitigation measures have been focused mainly on physical aspects, and few studies have addressed vulnerability and resilience in a multidimensional approach. The main objective of the present work is to assess changes in vulnerability and, consequently, risk, considering a time-space dimension. Three deterministic tsunami scenarios based on historical events were analyzed, an…
A sustainability index for anthropized and urbanized coasts
Inflammatory Biomarkers, Microbiome, Depression, and Executive Dysfunction in Alcohol Users
Alcohol-related disorders (ARD) are highly prevalent among Latin American-Caribbean countries. Mental disorders are common comorbidities in individuals with ARD. However, the etiology of the association between ARD and mental disorders remains unclear. We examined the association of inflammatory cytokines, microbiome, and other biomakers with measures of depression, social anxiety, and executive functions. We observed a significant increase in cy…
Testing Broken Windows Theory in Mexico City
Objectives To test the broken windows theory in the Mexican context. Methods Publicly available homicide counts and census data at the neighborhood level were used. Broken windows theory was operationalized through the use of social disorder and physical disorder measures. Measures were both calculated using PCA. For data analysis, we employed four multilevel random intercept models to relate homicide counts to our broken windows components. Resu…
Short Communication
The HIV-1 integrase viral protein is responsible for incorporating the viral DNA into the genomic DNA. The inhibition of viral integration into host cell DNA is part of recent therapeutic procedures. Combination therapy with protease and reverse transcriptase inhibitors has demonstrated good synergistic results in reducing viral replication. The purpose of this study is to assess the occurrence of integrase drug resistance mutations from the peri…
Un día en la vida de docente y estudiante virtual
En este trabajo presentamos un análisis de narraciones elaboradas por un grupo de residentes de dos profesorados universitarios de Argentina durante el primer semestre de 2020. Como equipo a cargo de las Prácticas Docentes nos posicionamos político-pedagógicamente desde la Educación Popular Latinoamericana, apuntando a la formación de profesionales reflexivos/as, que puedan desarrollar una mirada crítica. En los inicios del periodo de aislamiento…
Stressors and Impact of the Covid-19 Pandemic on Vulnerable Hispanic Caregivers and Children
Psychological sequelae are important elements of the burden of disease among caregivers. Recognition of the impact of adversity and stress biomarkers is important to prevent mental health problems that affect rearing practices and child well-being. This cross-sectional study explored social determinants of health (SDoH)-mediated stressors during COVID-19 and risks for mental health problems among caregivers of children with prenatal Zika virus ex…
Genomic Surveillance of Sars-CoV-2 Variants in the Dominican Republic and Emergence of a Local Lineage
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an RNA virus that evolves over time, leading to new variants. In the current study, we assessed the genomic epidemiology of SARS-CoV-2 in the Dominican Republic. A total of 1149 SARS-CoV-2 complete genome nucleotide sequences from samples collected between March 2020 and mid-February 2022 in the Dominican Republic were obtained from the Global Initiative on Sharing All Influenza Data…
Building multi-sectoral alliances to co-design and pilot a gender-transformative comprehensive sexuality education intervention for adolescents
Medicine (7 works) · Biology (6 works) · Psychology (5 works) · Gene (4 works) · Genetics (4 works) · Virology (4 works) · Environmental health (3 works) · Geography (3 works) · HIV Research and Treatment (3 works) · HIV/AIDS drug development and treatment (3 works)