Bong-Soo Park
Biographic Data
| ID | 4160880 |
|---|---|
| NAME | Bong-Soo Park |
| GIVEN NAMES | Bong-Soo |
| FAMILY NAME | Park |
| SIGNATURE | PARK B |
| AFFILIATIONS | Pusan National University |
| ORCID | 0000-0002-9799-5627 |
| VERIFIED | Yes |
| TOTAL WORKS | 10 |
| TOTAL CITATIONS | 1 |
| AUTHOR COUNT | 10 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2001 |
| LATEST PUBLICATION YEAR | 2015 |
| H-INDEX | 1 |
Antioxidant Effect of Eugenol in Human Periodontal Ligament Fibroblasts
Periodontal disease (PD) is the most common osteolytic disease of alveolar bone, oral infection seen in humans worldwide. PD is a common, chronic immunoinflammatory disease initiated by a complex subgingival bacterial and results in the inflammatory destruction of periodontal tissues, including the alveolar bone periodontal ligament, and gingivae. The effects of eugenol on periodontal ligament fibroblasts (PDLF) cell under oxidative injury have n…
Mechanism Underlying NaF-induced Apoptosis and Cell Cycle Arrest on G361 Human Melanoma Cell Line
Fluoride is widely used in dentistry to prevent dental caries, even though the safety of fluoride is a controversial issue. There are no known adverse effects of long-term fluoride ingestion for caries prevention, but an overdose can cause serious acute toxicity. Nevertheless it is accepted that fluoride is an important material for oral health. This study was undertaken to investigate the modulation of cell cycle-related proteins and apoptosis i…
Apoptotic Effect of Co-Treatment with a Natural Product, Chios Gum Mastic, and a Synthetic Chenodeoxycholic Acid Derivative, HS-1200, on Human Osteosarcoma Cells
Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently it reported that CGM induced apoptosis in a few cancer cells in vitro. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. This study was undertaken to investigate the synergistic apoptotic effect…
Histomorphometric Characteristics of the Facial Nerve
With the development of microsurgery, autogenous nerve grafting is being used widely in the treatment of the injured facial nerve. To use a donor graft for repair of the facial nerve, fascicular area and fascicular number should be considered in the selection of the donor site. This study demonstrated a detailed morphologic description of the facial nerve, including a microscopic assessment of nerve size and shape, and fascicular number and diame…
Chios Gum Mastic Induces Cell Cycle Arrest and Apoptosis in YD9 Human Oral Squamous Carcinoma Cells
Chios gum mastic (CGM) is obtained from the stem and leaves of Pistacia lentiscus trees and has been extensively used for centuries in Mediterranean and Middle Eastern countries, both as a dietary supplement and herbal remedy. This study was undertaken to examine in vitro effects of cytotoxicity and growth inhibition, and the molecular mechanism underlying modulation of cell cycle and induction of apoptosis in YD9 human oral squamous carcinoma ce…
A purified extract from Clematis mandshurica prevents staurosporin-induced downregulation of 14-3-3 and subsequent apoptosis on rat chondrocytes
Translocation of Phospho-ser 15-p53 in Eugenol-induced Apoptosis of in vitro Cultured Cancer Cells
Eugenol (4-allyl-2-methoxyphenol), a major ingredient of herbs such as clove and Magnoliae Flos, is known to induce apoptosis in mast cells via p53 pathway. This study was undertaken to examine the in vivo effect of eugenol and the molecular mechanism underlying eugenol-induced apoptosis in several cancer cells with different p53 status. Effect of eugenol on mesenteric mast cells was tested using a rat anaphylaxis model. And TUNEL staining was co…
Synthetic Chenodeoxycholic Acid Derivative HS-1200-induced Apoptosis of Human Melanoma Cells
Bile acids and their synthetic derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. It wasn’t discovered those materials have apoptosis-inducing effects on G361 human melanoma cells. The present study was done to examine the synthetic bile acid derivatives, HS-1199 …
Characteristics of Mitochondrial Events in Synthetic Bile Acids-induced Apoptosis of Human Osteosarcoma Cells
담즙산 유도체 HS-1200에 의한 골육종세포의 세포자멸사에서 사립체 관련 현상을 연구하였다. HS-1200은 사립체의 주요 세포자멸사 관련 인자인 cytochrome c와 Smac/DIABLO의 방출을 유도하였다. 이런 형태의 세포자멸사에서 cytochrome c 방출은 caspase 억제제로 막아지지 않았으나 Smac/DIABLO의 방출은 막아졌다. PTP 억제제인 BKA는 cytochrome c와 Smac/DIABLO 모두의 방출을 막지 못하였다. 흥미롭게도 JC-1 dye를 사용하여 측정한 결과 MMP의 변화가 관찰되지 않았다. 이를 확인하기 위하여 MitoTracker, DiOC-6 및 Rhodamine123 등을 사용하여 MMP를 측정하여도 감소는 관찰되지 않았다. 이런 현상이 세포자멸사 신호에 특이한지 혹은 세포에 특이한지를 조사한 결과 genistein 투여 후에도 MMP 감소가 …
The Role of CD44 in the Adhesion of Human Osteosarcoma to Hyaluronic Acid
Translocation of Phospho-ser 15-p53 in Eugenol-induced Apoptosis of in vitro Cultured Cancer Cells
Eugenol (4-allyl-2-methoxyphenol), a major ingredient of herbs such as clove and Magnoliae Flos, is known to induce apoptosis in mast cells via p53 pathway. This study was undertaken to examine the in vivo effect of eugenol and the molecular mechanism underlying eugenol-induced apoptosis in several cancer cells with different p53 status. Effect of eugenol on mesenteric mast cells was tested using a rat anaphylaxis model. And TUNEL staining was co…
The Role of CD44 in the Adhesion of Human Osteosarcoma to Hyaluronic Acid
Characteristics of Mitochondrial Events in Synthetic Bile Acids-induced Apoptosis of Human Osteosarcoma Cells
담즙산 유도체 HS-1200에 의한 골육종세포의 세포자멸사에서 사립체 관련 현상을 연구하였다. HS-1200은 사립체의 주요 세포자멸사 관련 인자인 cytochrome c와 Smac/DIABLO의 방출을 유도하였다. 이런 형태의 세포자멸사에서 cytochrome c 방출은 caspase 억제제로 막아지지 않았으나 Smac/DIABLO의 방출은 막아졌다. PTP 억제제인 BKA는 cytochrome c와 Smac/DIABLO 모두의 방출을 막지 못하였다. 흥미롭게도 JC-1 dye를 사용하여 측정한 결과 MMP의 변화가 관찰되지 않았다. 이를 확인하기 위하여 MitoTracker, DiOC-6 및 Rhodamine123 등을 사용하여 MMP를 측정하여도 감소는 관찰되지 않았다. 이런 현상이 세포자멸사 신호에 특이한지 혹은 세포에 특이한지를 조사한 결과 genistein 투여 후에도 MMP 감소가 …
A purified extract from Clematis mandshurica prevents staurosporin-induced downregulation of 14-3-3 and subsequent apoptosis on rat chondrocytes
Translocation of Phospho-ser 15-p53 in Eugenol-induced Apoptosis of in vitro Cultured Cancer Cells
Eugenol (4-allyl-2-methoxyphenol), a major ingredient of herbs such as clove and Magnoliae Flos, is known to induce apoptosis in mast cells via p53 pathway. This study was undertaken to examine the in vivo effect of eugenol and the molecular mechanism underlying eugenol-induced apoptosis in several cancer cells with different p53 status. Effect of eugenol on mesenteric mast cells was tested using a rat anaphylaxis model. And TUNEL staining was co…
Synthetic Chenodeoxycholic Acid Derivative HS-1200-induced Apoptosis of Human Melanoma Cells
Bile acids and their synthetic derivatives induced apoptosis in various kinds of cancer cells and anticancer effects. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. It wasn’t discovered those materials have apoptosis-inducing effects on G361 human melanoma cells. The present study was done to examine the synthetic bile acid derivatives, HS-1199 …
Apoptotic Effect of Co-Treatment with a Natural Product, Chios Gum Mastic, and a Synthetic Chenodeoxycholic Acid Derivative, HS-1200, on Human Osteosarcoma Cells
Chios gum mastic (CGM) is a resinous exudate obtained from the stem and the main leaves of Pistacia lenticulus tree native to Mediterranean areas. Recently it reported that CGM induced apoptosis in a few cancer cells in vitro. It has been reported that the synthetic chenodeoxycholic acid (CDCA) derivatives showed apoptosis-inducing activity on various cancer cells in vitro. This study was undertaken to investigate the synergistic apoptotic effect…
Histomorphometric Characteristics of the Facial Nerve
With the development of microsurgery, autogenous nerve grafting is being used widely in the treatment of the injured facial nerve. To use a donor graft for repair of the facial nerve, fascicular area and fascicular number should be considered in the selection of the donor site. This study demonstrated a detailed morphologic description of the facial nerve, including a microscopic assessment of nerve size and shape, and fascicular number and diame…
Chios Gum Mastic Induces Cell Cycle Arrest and Apoptosis in YD9 Human Oral Squamous Carcinoma Cells
Chios gum mastic (CGM) is obtained from the stem and leaves of Pistacia lentiscus trees and has been extensively used for centuries in Mediterranean and Middle Eastern countries, both as a dietary supplement and herbal remedy. This study was undertaken to examine in vitro effects of cytotoxicity and growth inhibition, and the molecular mechanism underlying modulation of cell cycle and induction of apoptosis in YD9 human oral squamous carcinoma ce…
Mechanism Underlying NaF-induced Apoptosis and Cell Cycle Arrest on G361 Human Melanoma Cell Line
Fluoride is widely used in dentistry to prevent dental caries, even though the safety of fluoride is a controversial issue. There are no known adverse effects of long-term fluoride ingestion for caries prevention, but an overdose can cause serious acute toxicity. Nevertheless it is accepted that fluoride is an important material for oral health. This study was undertaken to investigate the modulation of cell cycle-related proteins and apoptosis i…
Antioxidant Effect of Eugenol in Human Periodontal Ligament Fibroblasts
Periodontal disease (PD) is the most common osteolytic disease of alveolar bone, oral infection seen in humans worldwide. PD is a common, chronic immunoinflammatory disease initiated by a complex subgingival bacterial and results in the inflammatory destruction of periodontal tissues, including the alveolar bone periodontal ligament, and gingivae. The effects of eugenol on periodontal ligament fibroblasts (PDLF) cell under oxidative injury have n…
Biochemistry (9 works) · Biology (9 works) · Apoptosis (8 works) · Chemistry (8 works) · Molecular Biology (7 works) · Medicine (5 works) · Cancer Research (4 works) · Cell Biology (4 works) · Cytochrome c (3 works) · Gene (3 works)