Elizabeth A Holdsworth
Biographic Data
| ID | 4192647 |
|---|---|
| NAME | Elizabeth A Holdsworth |
| GIVEN NAMES | Elizabeth A |
| FAMILY NAME | Holdsworth |
| SIGNATURE | HOLDSWORTH E A |
| AFFILIATIONS | Washington State University |
| ORCID | 0000-0001-6095-2378 |
| VERIFIED | Yes |
| TOTAL WORKS | 9 |
| TOTAL CITATIONS | 6 |
| AUTHOR COUNT | 9 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2017 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Postpartum Maternal Stress is Unrelated to the Infant Fecal Microbiome, but is Associated With the Human Milk Microbiome in Exclusively Breastfeeding Mother‐Infant Dyads: The Mother‐Infant Microbiomes…
Objectives This study aimed to evaluate whether postpartum maternal stress is associated with infant gastrointestinal microbiome composition and diversity, and whether this relationship may be mediated by maternal caregiving and breastfeeding behaviors and human milk microbiome (HMM) composition. Methods Infant fecal and human milk samples were collected from 51 exclusively breastfeeding mother‐infant dyads in the Pacific Northwest between 1 and …
Maternal–infant interaction quality is associated with child NR3C1 CpG site methylation at 7 years of age
OBJECTIVE: Infancy is both a critical window for hypothalamic-pituitary-adrenal (HPA) axis development, and a sensitive period for social-emotional influences. We hypothesized that the social-emotional quality of maternal-infant interactions are associated with methylation of HPA-axis gene NR3C1 later in childhood. METHODS: Using a subsample of 114 mother-infant pairs from the Avon Longitudinal Study of Parents and Children (ALSPAC), linear regre…
Hackademics: Hacks toward success in academia
OBJECTIVE: The Sausage of Science is a podcast for the Human Biology Association and the American Journal of Human Biology through which we introduced a special series called #Hackademics. The podcast was initially used to highlight the scholarship and humanity of fellow human biologists through interviews about "how the sausage is made" in research-that is, the nuts and bolts that go into our publications. However, we soon realized there is much…
Gendered impacts of the Covid-19 pandemic: A Mixed-Method Study of Teacher Stress and Work-Life Balance
There is a growing concern that the COVID-19 pandemic has had disproportionate impacts on women, especially those with children. Female educators, and, in particular, those with childcare responsibilities, have also reported higher levels of stress and work-life challenges as compared to their male counterparts. It is unclear exactly which factors are behind these disparities. However, while some have pointed to the gendered division of domestic …
Prenatal Lead and Depression Exposures Jointly Influence Birth Outcomes and NR3C1 DNA Methylation
Many gestational exposures influence birth outcomes, yet the joint contribution of toxicant and psychosocial factors is understudied. Moreover, associated gestational epigenetic mechanisms are unknown. Lead (Pb) and depression independently influence birth outcomes and offspring NR3C1 (glucocorticoid receptor) DNA methylation. We hypothesized that gestational Pb and depression would jointly influence birth outcomes and NR3C1 methylation. Pregnanc…
Prenatal Exposure to Favorable Social and Environmental Neighborhood Conditions Is Associated with Healthy Pregnancy and Infant Outcomes
Neighborhood and individual level risks commonly co-occur for pregnant women and may cumulatively contribute to birth outcomes. Moreover, the relationship between favorable social and environmental neighborhood conditions and perinatal outcomes has been understudied. This study considered the accumulated impact of prenatal exposure to positive neighborhood social, environmental, and educational conditions in relation to maternal health during pre…
Adverse childhood experiences and reproductive strategies in a contemporary U.S. population
OBJECTIVES: Stressful experiences may initiate developmentally plastic responses toward a faster reproductive strategy. This study tests whether adverse childhood experiences (ACEs) are associated with characteristics of faster reproductive strategies: earlier menarche and reduced prenatal investment in offspring in a well-nourished, low-immune system burden population. MATERIALS AND METHODS: We analyzed the first 214 enrollees of the prenatal-bi…
Social Support During Pregnancy Modifies the Association Between Maternal Adverse Childhood Experiences and Infant Birth Size
Maternal‐infant interaction as an influence on infant adiposity
OBJECTIVES: The aim of this research is to identify whether specific aspects of the early life psychosocial environment such as quality of home and maternal-infant interaction are associated with increased infant adiposity, in a disadvantaged population in the United States. METHODS: Data on 121 mother-infant pairs from the Albany Pregnancy and Infancy Lead Study were analyzed using three multiple linear regression models with subscapular skinfol…
Gendered impacts of the Covid-19 pandemic: A Mixed-Method Study of Teacher Stress and Work-Life Balance
There is a growing concern that the COVID-19 pandemic has had disproportionate impacts on women, especially those with children. Female educators, and, in particular, those with childcare responsibilities, have also reported higher levels of stress and work-life challenges as compared to their male counterparts. It is unclear exactly which factors are behind these disparities. However, while some have pointed to the gendered division of domestic …
Adverse childhood experiences and reproductive strategies in a contemporary U.S. population
OBJECTIVES: Stressful experiences may initiate developmentally plastic responses toward a faster reproductive strategy. This study tests whether adverse childhood experiences (ACEs) are associated with characteristics of faster reproductive strategies: earlier menarche and reduced prenatal investment in offspring in a well-nourished, low-immune system burden population. MATERIALS AND METHODS: We analyzed the first 214 enrollees of the prenatal-bi…
Maternal‐infant interaction as an influence on infant adiposity
OBJECTIVES: The aim of this research is to identify whether specific aspects of the early life psychosocial environment such as quality of home and maternal-infant interaction are associated with increased infant adiposity, in a disadvantaged population in the United States. METHODS: Data on 121 mother-infant pairs from the Albany Pregnancy and Infancy Lead Study were analyzed using three multiple linear regression models with subscapular skinfol…
Social Support During Pregnancy Modifies the Association Between Maternal Adverse Childhood Experiences and Infant Birth Size
Adverse childhood experiences and reproductive strategies in a contemporary U.S. population
OBJECTIVES: Stressful experiences may initiate developmentally plastic responses toward a faster reproductive strategy. This study tests whether adverse childhood experiences (ACEs) are associated with characteristics of faster reproductive strategies: earlier menarche and reduced prenatal investment in offspring in a well-nourished, low-immune system burden population. MATERIALS AND METHODS: We analyzed the first 214 enrollees of the prenatal-bi…
Prenatal Lead and Depression Exposures Jointly Influence Birth Outcomes and NR3C1 DNA Methylation
Many gestational exposures influence birth outcomes, yet the joint contribution of toxicant and psychosocial factors is understudied. Moreover, associated gestational epigenetic mechanisms are unknown. Lead (Pb) and depression independently influence birth outcomes and offspring NR3C1 (glucocorticoid receptor) DNA methylation. We hypothesized that gestational Pb and depression would jointly influence birth outcomes and NR3C1 methylation. Pregnanc…
Prenatal Exposure to Favorable Social and Environmental Neighborhood Conditions Is Associated with Healthy Pregnancy and Infant Outcomes
Neighborhood and individual level risks commonly co-occur for pregnant women and may cumulatively contribute to birth outcomes. Moreover, the relationship between favorable social and environmental neighborhood conditions and perinatal outcomes has been understudied. This study considered the accumulated impact of prenatal exposure to positive neighborhood social, environmental, and educational conditions in relation to maternal health during pre…
Hackademics: Hacks toward success in academia
OBJECTIVE: The Sausage of Science is a podcast for the Human Biology Association and the American Journal of Human Biology through which we introduced a special series called #Hackademics. The podcast was initially used to highlight the scholarship and humanity of fellow human biologists through interviews about "how the sausage is made" in research-that is, the nuts and bolts that go into our publications. However, we soon realized there is much…
Gendered impacts of the Covid-19 pandemic: A Mixed-Method Study of Teacher Stress and Work-Life Balance
There is a growing concern that the COVID-19 pandemic has had disproportionate impacts on women, especially those with children. Female educators, and, in particular, those with childcare responsibilities, have also reported higher levels of stress and work-life challenges as compared to their male counterparts. It is unclear exactly which factors are behind these disparities. However, while some have pointed to the gendered division of domestic …
Maternal–infant interaction quality is associated with child NR3C1 CpG site methylation at 7 years of age
OBJECTIVE: Infancy is both a critical window for hypothalamic-pituitary-adrenal (HPA) axis development, and a sensitive period for social-emotional influences. We hypothesized that the social-emotional quality of maternal-infant interactions are associated with methylation of HPA-axis gene NR3C1 later in childhood. METHODS: Using a subsample of 114 mother-infant pairs from the Avon Longitudinal Study of Parents and Children (ALSPAC), linear regre…
Postpartum Maternal Stress is Unrelated to the Infant Fecal Microbiome, but is Associated With the Human Milk Microbiome in Exclusively Breastfeeding Mother‐Infant Dyads: The Mother‐Infant Microbiomes…
Objectives This study aimed to evaluate whether postpartum maternal stress is associated with infant gastrointestinal microbiome composition and diversity, and whether this relationship may be mediated by maternal caregiving and breastfeeding behaviors and human milk microbiome (HMM) composition. Methods Infant fecal and human milk samples were collected from 51 exclusively breastfeeding mother‐infant dyads in the Pacific Northwest between 1 and …
Medicine (8 works) · Pregnancy (6 works) · Biology (5 works) · Demography (4 works) · Obstetrics (4 works) · Psychology (4 works) · Genetics (3 works) · Psychiatry (3 works) · Birth weight (2 works) · Birth, Development, and Health (2 works)