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Leigh F Johnson

Biographic Data

ID4197548
NAMELeigh F Johnson
GIVEN NAMESLeigh F
FAMILY NAMEJohnson
SIGNATUREJOHNSON L F
AFFILIATIONSUniversity of Cape Town
ORCID0000-0002-2717-011X
VERIFIEDYes
TOTAL WORKS18
TOTAL CITATIONS2
WORKS AS AUTHOR18
WORKS AS EDITOR0
FIRST PUBLICATION YEAR2005
LATEST PUBLICATION YEAR2026
H-INDEX1
  • Towards ending tuberculosis in South Africa

    Open Access•Leigh F Johnson, Mmamapudi Kubjane et al.•ARTICLE•Global Health Action•2026

  • Suicidal thoughts and behaviours in Cape Town

    Open Access•Mpho Tlali, Reshma Kassanjee et al.•ARTICLE•SSM - Mental Health•2026

    Suicidal thoughts and behaviours (STBs) are traditionally attributed to mental disorders; however, increasing evidence indicates that social determinants contribute to suicide risk. We examined STBs and their socioeconomic, psychosocial and clinical correlates in two communities in Cape Town. We conducted psychiatric diagnostic interviews (MINI) at three public-sector facilities (2023-2024). Adults aged ≥18 years, with and without HIV, were recru…

  • Estimating the burden of mpox among MSM in South Africa

    Open Access•Ruth McCabe, Leigh F Johnson et al.•ARTICLE•BMJ Global Health•2025

    Despite seeing few cases during the 2022–2023 mpox global outbreak, reports in May–July 2024 of 22 cases among men-who-have-sex-with-men (MSM) in South Africa, including three deaths, have raised concerns about under-reported community transmission. We used a Monte Carlo simulation model to estimate the true epidemic size, considering the increased severity of mpox among MSM living with advanced HIV, documented over-representation of people livin…

  • Brief Report

    Open Access•Na’eem Kistnasamy, Danai Musuka et al.•ARTICLE•Population Research and Policy…•2025•References: 23

    Same-sex unions are increasingly common in high-income countries that have legally recognized same-sex unions, but data from other settings are limited. In 2006, South Africa became the fifth country in the world to legally recognize same-sex unions. This study uses data from the General Household Surveys conducted in South Africa between 2002 and 2022 (483,500 men and 584,303 women aged 18 or older) to determine the proportions of cohabiting uni…

  • A model-based approach to estimating the prevalence of disease combinations in South Africa

    Open Access•Leigh F Johnson, Reshma Kassanjee et al.•ARTICLE•BMJ Global Health•2024

    BACKGROUND: The development of strategies to better detect and manage patients with multiple long-term conditions requires estimates of the most prevalent condition combinations. However, standard meta-analysis tools are not well suited to synthesising heterogeneous multimorbidity data. METHODS: We developed a statistical model to synthesise data on associations between diseases and nationally representative prevalence estimates and applied the m…

  • Investigating the Associations between Drought, Poverty, High-Risk Sexual Behaviours, and HIV Incidence in Sub-Saharan Africa

    Open Access•Adam Trickey, Leigh F Johnson et al.•ARTICLE•AIDS and Behavior•2024

    Climate change is increasing the likelihood of drought in sub-Saharan Africa, where HIV prevalence is high. Drought could increase HIV transmission through various mediating mechanisms; we investigated these associations. We used data on people aged 15-59 from Population-Based HIV Impact Assessment surveys from 2016 in Eswatini, Lesotho, Tanzania, Uganda, and Zambia. Survey data were geospatially linked to precipitation data for 2014-2016, with l…

  • Trends and factors associated with illicit drug use in South Africa

    Open Access•Kennedy Kipkoech Mutai, Jack Stone et al.•ARTICLE•International Journal of Drug…•2024

    Illicit drug use has increased substantially in South Africa and is associated with numerous socio-demographic characteristics, higher sexual risk behaviours and other well-being variables

  • A quantitative assessment of the consistency of projections from five mathematical models of the HIV epidemic in South Africa

    Open Access•Haroon Moolla, Andrew Phillips et al.•ARTICLE•BMC Public Health•2023

    While models produced consistent estimates for several outputs, there are areas of variability that should be investigated. This is important if projections are to be used in subsequent cost-effectiveness studies

  • Diagnosis and treatment of opioid-related disorders in a South African private sector medical insurance scheme

    Open Access•Mpho Tlali, A Scheibe et al.•ARTICLE•International Journal of Drug…•2022

  • The cost effectiveness and optimal configuration of HIV self-test distribution in South Africa

    Open Access•Lise Jamieson, Leigh F Johnson et al.•ARTICLE•BMJ Global Health•2021

    BACKGROUND: HIV self-testing (HIVST) has been shown to be acceptable, feasible and effective in increasing HIV testing uptake. Novel testing strategies are critical to achieving the UNAIDS target of 95% HIV-positive diagnosis by 2025 in South Africa and globally. METHODS: We modelled the impact of six HIVST kit distribution modalities (community fixed-point, taxi ranks, workplace, partners of primary healthcare (PHC) antiretroviral therapy (ART) …

  • Advancing global health and strengthening the HIV response in the era of the Sustainable Development Goals

    Open Access•Linda-Gail Bekker, George A O Alleyne et al.•ARTICLE•The Lancet•2018

  • Precarious transition

    Open Access•Kim Bloch, Leigh F Johnson et al.•ARTICLE•BMC Public Health•2018

    This is the first long-term mortality assessment in the large ex-miner population from the South African mining industry. Mortality patterns follow that of the national HIV-tuberculosis epidemic and antiretroviral treatment availability. However, ex-miners have further elevated mortality and a very high mortality risk in the year after leaving the workforce. Coordinated action between the mining industry, governments and non-governmental organisa…

  • Designing an optimal HIV programme for South Africa

    Open Access•Calvin Chiu, Leigh F Johnson et al.•ARTICLE•BMC Public Health•2017

    Conventional league tables may exaggerate the cost-effectiveness of interventions when programmes are implemented at scale. Accounting for interaction and non-linear scale-up effects provides more realistic estimates in highly saturated real-world settings

  • Prospects for HIV control in South Africa

    Open Access•Leigh F Johnson, Calvin Chiu et al.•ARTICLE•Global Health Action•2016

    BACKGROUND: The goal of virtual elimination of horizontal and mother-to-child HIV transmission in South Africa (SA) has been proposed, but there have been few systematic investigations of which interventions are likely to be most critical to reducing HIV incidence. OBJECTIVE: This study aims to evaluate SA's potential to achieve virtual elimination targets and to identify which interventions will be most critical to achieving HIV incidence reduct…

  • Combination HIV prevention for female sex workers

    Open Access•Linda-Gail Bekker, Leigh Johnson et al.•ARTICLE•The Lancet•2015

  • The relationship between reproductive rights and prevalence of HIV among women in developing countries

    Leigh F Johnson•ARTICLE•Journal of Comparative Social…•2008•Cited by: 1•References: 10

    The rate of HIV infection among women in the developing world is rising. The goal of this study was to assess the effectiveness of a reproductive rights approach to reducing HIV rates among women in the developing world. Researchers proposed that reproductive rights mediated the relationship between gender equality and HIV rates. Data from 142 developing countries were used to test the proposed model. Researchers did not find that reproductive ri…

  • Modelling the demographic impact of HIV/Aids in South Africa and the likely impact of interventions

    Open Access•Leigh F Johnson, Rob Dorrington•ARTICLE•Demographic Research•2006•Cited by: 1•References: 52

    This paper describes an approach to incorporating the impact of HIV/AIDS and the effects of HIV/AIDS prevention and treatment programmes into a cohort component projection model of the South African population. The modelled HIV-positive population is d

  • Children ‘in need of care’ or in need of cash? Social security in the time of Aids

    Helen Meintjes, Debbie Budlender et al.•ARTICLE•Society in Transition•2005

    In the face of international pressure and local concern regarding the repercussions of the AIDS epidemic for children in South Africa, as well as the review underway of children's legislation in the country, there is much debate regarding social security provision for children in the context of HIV/AIDS. To date, the State's social security response to the impact of AIDS on children has been to focus its attention on the provision of the Foster C…

  • The relationship between reproductive rights and prevalence of HIV among women in developing countries

    Leigh F Johnson•ARTICLE•Journal of Comparative Social…•2008•Cited by: 1•References: 10

    The rate of HIV infection among women in the developing world is rising. The goal of this study was to assess the effectiveness of a reproductive rights approach to reducing HIV rates among women in the developing world. Researchers proposed that reproductive rights mediated the relationship between gender equality and HIV rates. Data from 142 developing countries were used to test the proposed model. Researchers did not find that reproductive ri…

  • Modelling the demographic impact of HIV/Aids in South Africa and the likely impact of interventions

    Open Access•Leigh F Johnson, Rob Dorrington•ARTICLE•Demographic Research•2006•Cited by: 1•References: 52

    This paper describes an approach to incorporating the impact of HIV/AIDS and the effects of HIV/AIDS prevention and treatment programmes into a cohort component projection model of the South African population. The modelled HIV-positive population is d

  • Children ‘in need of care’ or in need of cash? Social security in the time of Aids

    Helen Meintjes, Debbie Budlender et al.•ARTICLE•Society in Transition•2005

    In the face of international pressure and local concern regarding the repercussions of the AIDS epidemic for children in South Africa, as well as the review underway of children's legislation in the country, there is much debate regarding social security provision for children in the context of HIV/AIDS. To date, the State's social security response to the impact of AIDS on children has been to focus its attention on the provision of the Foster C…

  • Modelling the demographic impact of HIV/Aids in South Africa and the likely impact of interventions

    Open Access•Leigh F Johnson, Rob Dorrington•ARTICLE•Demographic Research•2006•Cited by: 1•References: 52

    This paper describes an approach to incorporating the impact of HIV/AIDS and the effects of HIV/AIDS prevention and treatment programmes into a cohort component projection model of the South African population. The modelled HIV-positive population is d

  • The relationship between reproductive rights and prevalence of HIV among women in developing countries

    Leigh F Johnson•ARTICLE•Journal of Comparative Social…•2008•Cited by: 1•References: 10

    The rate of HIV infection among women in the developing world is rising. The goal of this study was to assess the effectiveness of a reproductive rights approach to reducing HIV rates among women in the developing world. Researchers proposed that reproductive rights mediated the relationship between gender equality and HIV rates. Data from 142 developing countries were used to test the proposed model. Researchers did not find that reproductive ri…

  • Combination HIV prevention for female sex workers

    Open Access•Linda-Gail Bekker, Leigh Johnson et al.•ARTICLE•The Lancet•2015

  • Prospects for HIV control in South Africa

    Open Access•Leigh F Johnson, Calvin Chiu et al.•ARTICLE•Global Health Action•2016

    BACKGROUND: The goal of virtual elimination of horizontal and mother-to-child HIV transmission in South Africa (SA) has been proposed, but there have been few systematic investigations of which interventions are likely to be most critical to reducing HIV incidence. OBJECTIVE: This study aims to evaluate SA's potential to achieve virtual elimination targets and to identify which interventions will be most critical to achieving HIV incidence reduct…

  • Designing an optimal HIV programme for South Africa

    Open Access•Calvin Chiu, Leigh F Johnson et al.•ARTICLE•BMC Public Health•2017

    Conventional league tables may exaggerate the cost-effectiveness of interventions when programmes are implemented at scale. Accounting for interaction and non-linear scale-up effects provides more realistic estimates in highly saturated real-world settings

  • Advancing global health and strengthening the HIV response in the era of the Sustainable Development Goals

    Open Access•Linda-Gail Bekker, George A O Alleyne et al.•ARTICLE•The Lancet•2018

  • Precarious transition

    Open Access•Kim Bloch, Leigh F Johnson et al.•ARTICLE•BMC Public Health•2018

    This is the first long-term mortality assessment in the large ex-miner population from the South African mining industry. Mortality patterns follow that of the national HIV-tuberculosis epidemic and antiretroviral treatment availability. However, ex-miners have further elevated mortality and a very high mortality risk in the year after leaving the workforce. Coordinated action between the mining industry, governments and non-governmental organisa…

  • The cost effectiveness and optimal configuration of HIV self-test distribution in South Africa

    Open Access•Lise Jamieson, Leigh F Johnson et al.•ARTICLE•BMJ Global Health•2021

    BACKGROUND: HIV self-testing (HIVST) has been shown to be acceptable, feasible and effective in increasing HIV testing uptake. Novel testing strategies are critical to achieving the UNAIDS target of 95% HIV-positive diagnosis by 2025 in South Africa and globally. METHODS: We modelled the impact of six HIVST kit distribution modalities (community fixed-point, taxi ranks, workplace, partners of primary healthcare (PHC) antiretroviral therapy (ART) …

  • Diagnosis and treatment of opioid-related disorders in a South African private sector medical insurance scheme

    Open Access•Mpho Tlali, A Scheibe et al.•ARTICLE•International Journal of Drug…•2022

  • A quantitative assessment of the consistency of projections from five mathematical models of the HIV epidemic in South Africa

    Open Access•Haroon Moolla, Andrew Phillips et al.•ARTICLE•BMC Public Health•2023

    While models produced consistent estimates for several outputs, there are areas of variability that should be investigated. This is important if projections are to be used in subsequent cost-effectiveness studies

  • A model-based approach to estimating the prevalence of disease combinations in South Africa

    Open Access•Leigh F Johnson, Reshma Kassanjee et al.•ARTICLE•BMJ Global Health•2024

    BACKGROUND: The development of strategies to better detect and manage patients with multiple long-term conditions requires estimates of the most prevalent condition combinations. However, standard meta-analysis tools are not well suited to synthesising heterogeneous multimorbidity data. METHODS: We developed a statistical model to synthesise data on associations between diseases and nationally representative prevalence estimates and applied the m…

  • Investigating the Associations between Drought, Poverty, High-Risk Sexual Behaviours, and HIV Incidence in Sub-Saharan Africa

    Open Access•Adam Trickey, Leigh F Johnson et al.•ARTICLE•AIDS and Behavior•2024

    Climate change is increasing the likelihood of drought in sub-Saharan Africa, where HIV prevalence is high. Drought could increase HIV transmission through various mediating mechanisms; we investigated these associations. We used data on people aged 15-59 from Population-Based HIV Impact Assessment surveys from 2016 in Eswatini, Lesotho, Tanzania, Uganda, and Zambia. Survey data were geospatially linked to precipitation data for 2014-2016, with l…

  • Trends and factors associated with illicit drug use in South Africa

    Open Access•Kennedy Kipkoech Mutai, Jack Stone et al.•ARTICLE•International Journal of Drug…•2024

    Illicit drug use has increased substantially in South Africa and is associated with numerous socio-demographic characteristics, higher sexual risk behaviours and other well-being variables

  • Estimating the burden of mpox among MSM in South Africa

    Open Access•Ruth McCabe, Leigh F Johnson et al.•ARTICLE•BMJ Global Health•2025

    Despite seeing few cases during the 2022–2023 mpox global outbreak, reports in May–July 2024 of 22 cases among men-who-have-sex-with-men (MSM) in South Africa, including three deaths, have raised concerns about under-reported community transmission. We used a Monte Carlo simulation model to estimate the true epidemic size, considering the increased severity of mpox among MSM living with advanced HIV, documented over-representation of people livin…

  • Brief Report

    Open Access•Na’eem Kistnasamy, Danai Musuka et al.•ARTICLE•Population Research and Policy…•2025•References: 23

    Same-sex unions are increasingly common in high-income countries that have legally recognized same-sex unions, but data from other settings are limited. In 2006, South Africa became the fifth country in the world to legally recognize same-sex unions. This study uses data from the General Household Surveys conducted in South Africa between 2002 and 2022 (483,500 men and 584,303 women aged 18 or older) to determine the proportions of cohabiting uni…

  • Towards ending tuberculosis in South Africa

    Open Access•Leigh F Johnson, Mmamapudi Kubjane et al.•ARTICLE•Global Health Action•2026

  • Suicidal thoughts and behaviours in Cape Town

    Open Access•Mpho Tlali, Reshma Kassanjee et al.•ARTICLE•SSM - Mental Health•2026

    Suicidal thoughts and behaviours (STBs) are traditionally attributed to mental disorders; however, increasing evidence indicates that social determinants contribute to suicide risk. We examined STBs and their socioeconomic, psychosocial and clinical correlates in two communities in Cape Town. We conducted psychiatric diagnostic interviews (MINI) at three public-sector facilities (2023-2024). Adults aged ≥18 years, with and without HIV, were recru…

Medicine (15 works) · Environmental health (12 works) · Demography (11 works) · Population (11 works) · HIV/AIDS Research and Interventions (9 works) · HIV/AIDS Impact and Responses (6 works) · Sociology (6 works) · Adolescent Sexual and Reproductive Health (5 works) · Demography (5 works) · Economic growth (5 works)

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