Beverly H Brummett
Biographic Data
| ID | 4235435 |
|---|---|
| NAME | Beverly H Brummett |
| GIVEN NAMES | Beverly H |
| FAMILY NAME | Brummett |
| SIGNATURE | BRUMMETT B H |
| AFFILIATIONS | Duke University |
| VERIFIED | No |
| TOTAL WORKS | 31 |
| TOTAL CITATIONS | 76 |
| WORKS AS AUTHOR | 31 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 1995 |
| LATEST PUBLICATION YEAR | 2019 |
| H-INDEX | 4 |
The Effects of Tryptophan Enhancement and Depletion on Plasma Catecholamine Levels in Healthy Individuals
OBJECTIVE: Central nervous system (CNS) serotonin (5-HT) exerts both excitatory and inhibitory effects on the sympathetic nervous system (SNS) in animals. In this study, we examine the effects of tryptophan enhancement and depletion on plasma catecholamine levels in humans. METHODS: The total sample consisted of 164 healthy men and women who were tested for 2 days. Seventy-nine participants were randomized to a tryptophan enhancement condition an…
Systolic Blood Pressure and Socioeconomic Status in a large multi-study population
The present study used harmonized data from eight studies (N = 28,891) to examine the association between socioeconomic status (SES) and resting systolic blood pressure (SBP). The study replicates and extends our prior work on this topic by examining potential moderation of this association by race and gender. We also examined the extent to which body mass index (BMI), waist circumference (WC), and smoking might explain the association between SE…
Socioeconomic Indices as Independent Correlates of C-Reactive Protein in the National Longitudinal Study of Adolescent Health
OBJECTIVES: To examine the association between socioeconomic status (SES) and C-reactive protein (CRP) to understand how SES may increase the risk of cardiovascular disease and thus identify targets for prevention measures. METHODS: Path models were used to examine direct and indirect associations of four indices of SES (objective early life built environment ratings, parental and participant education, and income) with CRP measured during early …
Adult Development and Aging
In this chapter, we address research and theory in adult development and aging that have the potential to be important for aging research in health psychology and for opportunities for practice in clinical health psychology of aging in the decade ahead. These areas include (a) personality and prediction of disease, especially the potential for early Alzheimer's disease and other dementias; (b) cognitive declines leading to physical health changes…
Effects of 5HTTLPR on Cardiovascular Response to an Emotional Stressor
OBJECTIVES: To replicate a prior main effect of the serotonin transporter gene promoter (5HTTLPR) genotype on cardiovascular reactivity (CVR) and explore caregiver stress as a potential moderator of 5HTTLPR effects on CVR. On the basis of prior findings, we hypothesized that the more transcriptionally active allele variants would be associated with increased CVR. METHODS: Expression of the serotonin transporter is affected by the genotype of the …
Impact of Psychological Stress on the Associations Between Apolipoprotein E Variants and Metabolic Traits
OBJECTIVE: To examine the association between apolipoprotein E (APOE) gene variants and waist circumference, fasting plasma glucose, serum insulin, serum high-density lipoprotein cholesterol, and serum triglycerides, all metabolic traits known as cardiovascular disease (CVD) endophenotypes, in a population of stressed individuals and controls. Abdominal obesity, insulin resistance, elevated serum lipid concentration, and APOE polymorphisms have b…
Associations of Depressive Symptoms, Trait Hostility, and Gender With C-Reactive Protein and Interleukin-6 Response After Emotion Recall
OBJECTIVE: To examine the effects of depressive symptoms and hostility on changes in C-reactive protein (CRP) and interleukin (IL)-6 in response to an acute laboratory stressor. Depressive symptoms moderate the effect of trait hostility on circulating levels of CRP and IL-6. METHODS: The study included 307 men and 218 women, affording the opportunity to examine moderation by gender. Regression analyses were performed to examine depressive symptom…
Central Nervous System Serotonin and Clustering of Hostility, Psychosocial, Metabolic, and Cardiovascular Endophenotypes in Men
OBJECTIVE: To use measures of cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5HIAA) and genotype of a functional polymorphism of the monoamine oxidase A gene promoter (MAOA-uVNTR) to study the role of central nervous system (CNS) serotonin in clustering of hostility, other psychosocial, metabolic and cardiovascular endophenotypes. METHODS: In 86 healthy male volunteers, we evaluated CSF levels of the primary serotonin metabolite 5HIAA and …
Vulnerability genes or plasticity genes?
The classic diathesis-stress framework, which views some individuals as particularly vulnerable to adversity, informs virtually all psychiatric research on behavior-gene-environment (G x E) interaction. An alternative framework of 'differential susceptibility' is proposed, one which regards those most susceptible to adversity because of their genetic make up as simultaneously most likely to benefit from supportive or enriching experiences-or even…
Hostility and Fasting Glucose in African American Women
OBJECTIVE: To examine whether the relationship of hostility (HOST) to fasting glucose indices is moderated by sex and race. HOST has been associated with abnormalities in glucose metabolism. Prior studies suggested that this association may be more prevalent in women and in African American (AA) individuals. METHODS: A total of 565 healthy AA and white (W) men and women (mean age = 33 +/- 6 years) were assessed. HOST was measured by the 27-item v…
Prospective Study of Associations Among Positive Emotion and Functional Status in Older Patients With Coronary Artery Disease
We examined associations between positive emotion (PE) and functional status (Duke Activity Status Inventory) in 948 coronary artery disease (CAD) patients (35.1% women; age M = 70.1 years, SD = 6.3). Emotion and function measures were gathered during hospitalization and annually for 3 years. We used random coefficient models to examine PE during hospitalization and follow-up, as a predictor of change in function. Analyses adjusted for baseline f…
Childhood Socioeconomic Status and Serotonin Transporter Gene Polymorphism Enhance Cardiovascular Reactivity to Mental Stress
OBJECTIVE: To test the hypothesis that low socioeconomic status (SES) and the 5HTTLPR L allele are associated with increased cardiovascular reactivity (CVR) to stress in a larger sample and that SES and 5HTTLPR genotypes interact to enhance CVR to stress. CVR to mental stress has been proposed as one mechanism linking stress to the pathogenesis of cardiovascular disease. The more transcriptionally efficient long (L) allele of a polymorphism of th…
Personality as a Predictor of Dietary Quality in Spouses During Midlife
The authors evaluated the NEO Personality Inventory-Revised (NEO-PI-R) as a predictor of dietary quality in 850 married couples, focusing on associations among each participant's personality as a predictor of their own dietary quality and their spouses' dietary quality. Diet was based on a modified version of the US Department of Agriculture Healthy Eating Index. Openness was associated with self-ratings of dietary quality for wives (r = .28) and…
Associations of a Regulatory Polymorphism of Monoamine Oxidase-A Gene Promoter (Maoa-uVNTR) With Symptoms of Depression and Sleep Quality
OBJECTIVE: To examine the relationships among the variable number of tandem repeats in the monoamine oxidase-A linked polymorphic region allelic variation (MAOA-uVNTR) and the symptoms of depression and sleep quality. The monoamine oxidase-A (MAOA) gene, which plays a vital role in degradation of neurotransmitters such as serotonin, norepinephrine, and dopamine, contains a polymorphism in its promoter region (MAOA-uVNTR) that affects transcriptio…
Sleep Quality Varies as a Function of 5-HTTLPR Genotype and Stress
OBJECTIVE: To test the hypothesis that allelic variation in 5HTT gene-linked polymorphic region (5-HTTLPR) genotype was associated with sleep quality (Pittsburgh Sleep Quality Index, PSQI) as a main effect and as moderated by the chronic stress of caregiving. Serotonin (5HT) is involved in sleep regulation and the 5HT transporter (5HTT) regulates 5HT function. A common 44-base pair deletion (s allele) polymorphism in the 5-HTTLPR is associated wi…
NEO personality domains and gender predict levels and trends in body mass index over 14 years during midlife
Perceived Social Support as a Predictor of Mortality in Coronary Patients
OBJECTIVE: Numerous studies have shown network assessments of social contact predict mortality in patients with coronary artery disease (CAD). Fewer studies have demonstrated an association between perceived social support and longevity in patient samples. It has been suggested that 1 of the mechanisms linking social support with elevated risk for mortality is the association between social support and other risk factors associated with decreased…
Neighborhood Characteristics Moderate Effects of Caregiving on Glucose Functioning
Objective: Adverse neighborhood environments and caregiving for a relative with dementia are both stressors that have been associated with poor health. The present study examined the extent to which three self-report measures of neighborhood characteristics interact with caregiving status (caregiver versus noncaregiver) to modify an important stress related health outcome: plasma glucose. Methods: The study sample consisted of 147 community recru…
Effect of Race on Cultural Justifications for Caregiving
This study supports the long-standing cultural tradition of African American families providing care to dependent elders. Cultural reasons for caregiving need to be interpreted within the context of race and gender socialization. Social roles, such as husband or wife, son or daughter, can also help determine how individuals within a particular cultural group experience cultural expectations and obligations. Information from this study can inform …
Hostility as a Predictor of Survival in Patients With Coronary Artery Disease
OBJECTIVE: This article presents a reanalysis of an earlier study that reported a nonsignificant relation between the 50-item Cook-Medley Hostility Scale (CMHS) and survival in a sample of coronary patients. Since publication of those results, there have been significant developments in the measurement of hostility that suggest that an abbreviated scale may be a better predictor of health outcomes. This study examined the ability of the total CMH…
Patterns of Change in Hostility from College to Midlife in the UNC Alumni Heart Study Predict High-Risk Status
OBJECTIVE: To examine hostility measured in college and patterns of change in hostility from college to midlife as predictors of high health-related risk later in midlife. METHODS: Logistic regression models were used to test hostility/risk associations. RESULTS: College hostility predicted being a current smoker, consuming more than two drinks of alcohol, low social support, achieving less than expected in career and in relationships, risk for d…
Characteristics of Socially Isolated Patients With Coronary Artery Disease Who Are at Elevated Risk for Mortality
OBJECTIVES: Social isolation has been linked to poor survival in patients with coronary artery disease (CAD). Few studies have closely examined the psychosocial characteristics of CAD patients who lack social contact. METHODS: Social isolation was examined as a predictor of mortality in 430 patients with significant CAD. More isolated patients were compared with their less isolated counterparts on factors that might help explain the association b…
Depressive Symptoms and Survival of Patients With Coronary Artery Disease
OBJECTIVE: Multiple studies have shown that high levels of depressive symptoms increase the mortality risk of patients with established coronary disease. This investigation divided depressive symptoms into groups to assess their relative effectiveness in predicting survival. METHODS: Questionnaires about the presence of depressive symptoms were administered to 1250 patients with significant coronary disease while they were hospitalized for diagno…
Social support and quality of life in patients with coronary artery disease
Cardiovascular Reactivity Associated With Induced Anger and Depressive Affect
Brummett, B. H.; Lane, J. D.; Merritt, M.; Sheaks, J.; Siegler, I. C.; Barefoot, J. C. Author Information
Effect of Race on Cultural Justifications for Caregiving
This study supports the long-standing cultural tradition of African American families providing care to dependent elders. Cultural reasons for caregiving need to be interpreted within the context of race and gender socialization. Social roles, such as husband or wife, son or daughter, can also help determine how individuals within a particular cultural group experience cultural expectations and obligations. Information from this study can inform …
Empathy and the collective good
We predicted that feeling empathy for another member of the collective in a social dilemma would create an altruistic desire to allocate resources to that person as an individual, reducing collective good. To test this prediction, 2 studies were run. In each, participants faced a dilemma in which they could choose to benefit themselves, the group, or other group members as individuals. In Study 1, empathy for another group member was manipulated;…
NEO personality domains and gender predict levels and trends in body mass index over 14 years during midlife
The Relationship between Self-Rated Health and Health Status among Coronary Artery Patients
A single item measure of SRH may be useful; the generalizability of the item must be considered. In this sample of CAD patients, SRH was related more to psychosocial factors than to clinical and disease indicators
Prospective Study of Associations Among Positive Emotion and Functional Status in Older Patients With Coronary Artery Disease
We examined associations between positive emotion (PE) and functional status (Duke Activity Status Inventory) in 948 coronary artery disease (CAD) patients (35.1% women; age M = 70.1 years, SD = 6.3). Emotion and function measures were gathered during hospitalization and annually for 3 years. We used random coefficient models to examine PE during hospitalization and follow-up, as a predictor of change in function. Analyses adjusted for baseline f…
Empathy and the collective good
We predicted that feeling empathy for another member of the collective in a social dilemma would create an altruistic desire to allocate resources to that person as an individual, reducing collective good. To test this prediction, 2 studies were run. In each, participants faced a dilemma in which they could choose to benefit themselves, the group, or other group members as individuals. In Study 1, empathy for another group member was manipulated;…
Social Support and Hostility as Predictors of Depressive Symptoms in Cardiac Patients One Month After Hospitalization
OBJECTIVE: Hospitalization for cardiac disease is associated with an increased risk for depression, which itself confers a poorer prognosis. Few prospective studies have examined the determinants of depression after hospitalization in cardiac patients, and even fewer have examined depression within the weeks after hospital discharge. The present study assessed the prospective relations among perceptions of social support and trait hostility in pr…
Social Support and Hostility Predict Depression 1 Month Following Diagnostic Angiography
Brummett, Beverly H.; Babyak, Michael A.; Barefoot, John C.; Bosworth, Hayden B.; Clapp-Channing, Nancy E.; Harwood, Russell W.; Siegler, Ilene C.; Williams, Redford B. Jr.; Mark, Daniel B. Author Information
Cardiovascular Reactivity Associated With Induced Anger and Depressive Affect
Brummett, B. H.; Lane, J. D.; Merritt, M.; Sheaks, J.; Siegler, I. C.; Barefoot, J. C. Author Information
Are the Salutogenic Effects of Social Supports Modified by Income
Vitaliano, P. P.; Scanlan, J. M.; Zhang, J.; Savage, M. V.; Dyck, D.; Barefoot, J.; Brummett, B.; Siegler, I. Author Information
The Relationship between Self-Rated Health and Health Status among Coronary Artery Patients
A single item measure of SRH may be useful; the generalizability of the item must be considered. In this sample of CAD patients, SRH was related more to psychosocial factors than to clinical and disease indicators
The Association Between Self-Rated Health and Mortality in a Well-Characterized Sample of Coronary Artery Disease Patients
BACKGROUND: The relationship between self-rated health and mortality after adjustment for sociodemographic variables, physician-rated comorbidities, disease severity, health-related quality of life (HRQOL), and psychosocial measures (depression, social support, and functional ability) was examined in the Mediators of Social Support (MOSS) study. SUBJECTS: The sample consisted of 2,885 individuals (mean age, 62.5 years) who had significant heart d…
Depressive Symptoms and Survival of Patients With Coronary Artery Disease
OBJECTIVE: Multiple studies have shown that high levels of depressive symptoms increase the mortality risk of patients with established coronary disease. This investigation divided depressive symptoms into groups to assess their relative effectiveness in predicting survival. METHODS: Questionnaires about the presence of depressive symptoms were administered to 1250 patients with significant coronary disease while they were hospitalized for diagno…
Social support and quality of life in patients with coronary artery disease
Characteristics of Socially Isolated Patients With Coronary Artery Disease Who Are at Elevated Risk for Mortality
OBJECTIVES: Social isolation has been linked to poor survival in patients with coronary artery disease (CAD). Few studies have closely examined the psychosocial characteristics of CAD patients who lack social contact. METHODS: Social isolation was examined as a predictor of mortality in 430 patients with significant CAD. More isolated patients were compared with their less isolated counterparts on factors that might help explain the association b…
Patterns of Change in Hostility from College to Midlife in the UNC Alumni Heart Study Predict High-Risk Status
OBJECTIVE: To examine hostility measured in college and patterns of change in hostility from college to midlife as predictors of high health-related risk later in midlife. METHODS: Logistic regression models were used to test hostility/risk associations. RESULTS: College hostility predicted being a current smoker, consuming more than two drinks of alcohol, low social support, achieving less than expected in career and in relationships, risk for d…
Hostility as a Predictor of Survival in Patients With Coronary Artery Disease
OBJECTIVE: This article presents a reanalysis of an earlier study that reported a nonsignificant relation between the 50-item Cook-Medley Hostility Scale (CMHS) and survival in a sample of coronary patients. Since publication of those results, there have been significant developments in the measurement of hostility that suggest that an abbreviated scale may be a better predictor of health outcomes. This study examined the ability of the total CMH…
Perceived Social Support as a Predictor of Mortality in Coronary Patients
OBJECTIVE: Numerous studies have shown network assessments of social contact predict mortality in patients with coronary artery disease (CAD). Fewer studies have demonstrated an association between perceived social support and longevity in patient samples. It has been suggested that 1 of the mechanisms linking social support with elevated risk for mortality is the association between social support and other risk factors associated with decreased…
Neighborhood Characteristics Moderate Effects of Caregiving on Glucose Functioning
Objective: Adverse neighborhood environments and caregiving for a relative with dementia are both stressors that have been associated with poor health. The present study examined the extent to which three self-report measures of neighborhood characteristics interact with caregiving status (caregiver versus noncaregiver) to modify an important stress related health outcome: plasma glucose. Methods: The study sample consisted of 147 community recru…
Effect of Race on Cultural Justifications for Caregiving
This study supports the long-standing cultural tradition of African American families providing care to dependent elders. Cultural reasons for caregiving need to be interpreted within the context of race and gender socialization. Social roles, such as husband or wife, son or daughter, can also help determine how individuals within a particular cultural group experience cultural expectations and obligations. Information from this study can inform …
NEO personality domains and gender predict levels and trends in body mass index over 14 years during midlife
Associations of a Regulatory Polymorphism of Monoamine Oxidase-A Gene Promoter (Maoa-uVNTR) With Symptoms of Depression and Sleep Quality
OBJECTIVE: To examine the relationships among the variable number of tandem repeats in the monoamine oxidase-A linked polymorphic region allelic variation (MAOA-uVNTR) and the symptoms of depression and sleep quality. The monoamine oxidase-A (MAOA) gene, which plays a vital role in degradation of neurotransmitters such as serotonin, norepinephrine, and dopamine, contains a polymorphism in its promoter region (MAOA-uVNTR) that affects transcriptio…
Sleep Quality Varies as a Function of 5-HTTLPR Genotype and Stress
OBJECTIVE: To test the hypothesis that allelic variation in 5HTT gene-linked polymorphic region (5-HTTLPR) genotype was associated with sleep quality (Pittsburgh Sleep Quality Index, PSQI) as a main effect and as moderated by the chronic stress of caregiving. Serotonin (5HT) is involved in sleep regulation and the 5HT transporter (5HTT) regulates 5HT function. A common 44-base pair deletion (s allele) polymorphism in the 5-HTTLPR is associated wi…
Childhood Socioeconomic Status and Serotonin Transporter Gene Polymorphism Enhance Cardiovascular Reactivity to Mental Stress
OBJECTIVE: To test the hypothesis that low socioeconomic status (SES) and the 5HTTLPR L allele are associated with increased cardiovascular reactivity (CVR) to stress in a larger sample and that SES and 5HTTLPR genotypes interact to enhance CVR to stress. CVR to mental stress has been proposed as one mechanism linking stress to the pathogenesis of cardiovascular disease. The more transcriptionally efficient long (L) allele of a polymorphism of th…
Personality as a Predictor of Dietary Quality in Spouses During Midlife
The authors evaluated the NEO Personality Inventory-Revised (NEO-PI-R) as a predictor of dietary quality in 850 married couples, focusing on associations among each participant's personality as a predictor of their own dietary quality and their spouses' dietary quality. Diet was based on a modified version of the US Department of Agriculture Healthy Eating Index. Openness was associated with self-ratings of dietary quality for wives (r = .28) and…
Vulnerability genes or plasticity genes?
The classic diathesis-stress framework, which views some individuals as particularly vulnerable to adversity, informs virtually all psychiatric research on behavior-gene-environment (G x E) interaction. An alternative framework of 'differential susceptibility' is proposed, one which regards those most susceptible to adversity because of their genetic make up as simultaneously most likely to benefit from supportive or enriching experiences-or even…
Hostility and Fasting Glucose in African American Women
OBJECTIVE: To examine whether the relationship of hostility (HOST) to fasting glucose indices is moderated by sex and race. HOST has been associated with abnormalities in glucose metabolism. Prior studies suggested that this association may be more prevalent in women and in African American (AA) individuals. METHODS: A total of 565 healthy AA and white (W) men and women (mean age = 33 +/- 6 years) were assessed. HOST was measured by the 27-item v…
Prospective Study of Associations Among Positive Emotion and Functional Status in Older Patients With Coronary Artery Disease
We examined associations between positive emotion (PE) and functional status (Duke Activity Status Inventory) in 948 coronary artery disease (CAD) patients (35.1% women; age M = 70.1 years, SD = 6.3). Emotion and function measures were gathered during hospitalization and annually for 3 years. We used random coefficient models to examine PE during hospitalization and follow-up, as a predictor of change in function. Analyses adjusted for baseline f…
Impact of Psychological Stress on the Associations Between Apolipoprotein E Variants and Metabolic Traits
OBJECTIVE: To examine the association between apolipoprotein E (APOE) gene variants and waist circumference, fasting plasma glucose, serum insulin, serum high-density lipoprotein cholesterol, and serum triglycerides, all metabolic traits known as cardiovascular disease (CVD) endophenotypes, in a population of stressed individuals and controls. Abdominal obesity, insulin resistance, elevated serum lipid concentration, and APOE polymorphisms have b…
Associations of Depressive Symptoms, Trait Hostility, and Gender With C-Reactive Protein and Interleukin-6 Response After Emotion Recall
OBJECTIVE: To examine the effects of depressive symptoms and hostility on changes in C-reactive protein (CRP) and interleukin (IL)-6 in response to an acute laboratory stressor. Depressive symptoms moderate the effect of trait hostility on circulating levels of CRP and IL-6. METHODS: The study included 307 men and 218 women, affording the opportunity to examine moderation by gender. Regression analyses were performed to examine depressive symptom…
Medicine (28 works) · Psychology (28 works) · Internal Medicine (23 works) · Internal Medicine (20 works) · Cardiac Health and Mental Health (17 works) · Clinical Psychology (15 works) · Psychiatry (12 works) · Health disparities and outcomes (10 works) · Coronary artery disease (9 works) · Gerontology (9 works)