Hilde Spielvogel
Dados Biográficos
| ID | 4289526 |
|---|---|
| NOME | Hilde Spielvogel |
| PRENOMES | Hilde |
| SOBRENOME | Spielvogel |
| ASSINATURA | SPIELVOGEL H |
| AFILIAÇÕES | Instituto Boliviano de Ciencia y Tecnología Nuclear |
| VERIFICADO | Não |
| TOTAL DE OBRAS | 23 |
| TOTAL DE CITAÇÕES | 71 |
| TOTAL COMO AUTOR | 23 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1982 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2024 |
| ÍNDICE H | 4 |
C‐reactive protein (CRP) in high altitude Bolivian peri‐urban adolescents varies by adiposity, current illness, height, socioeconomic status, sex, and menarcheal status
OBJECTIVES: In non-industrialized and low-income populations, adipose stores can serve as a valuable buffer against harsh conditions such as seasonal food scarcity. However, these reserves may incur costs due to adipocytes' production of pro-inflammatory cytokines; inflammation is associated with increased risk for cardiometabolic diseases later in life. Life history theory posits that, especially in populations with high juvenile mortality, high…
Recognizing normal reproductive biology
The idealized "normal" menstrual cycle typically comprises a coordinated ebb and flow of hormones over a 28-day span with ovulation invariably shown at the midpoint. It's a pretty picture-but rare. Systematic studies have debunked the myth that cycles occur regularly about every 28 days. However, assumptions persist regarding the extent and normalcy of variation in other cycle biomarkers. The processes of judging which phenotypic variants are "no…
Seasonal modulation of reproductive effort during early pregnancy in humans
Life history theory predicts that early pregnancy presents a relatively low cost, uncontested opportunity for a woman to terminate investment in a current reproductive opportunity if a conceptus is of poor quality and/or maternal status or environmental conditions are not propitious for a successful birth. We tested this hypothesis in rural Bolivian women experiencing substantial seasonal variation in workload and food resources. Significant risk…
Seasonal and circadian variation in salivary testosterone in rural Bolivian men
Testosterone (T) plays a key role in the increase and maintenance of muscle mass and bone density in adult men. Life history theory predicts that environmental stress may prompt a reallocation of such investments to those functions critical to survival. We tested this hypothesis in two studies of rural Bolivian adult men by comparing free T levels and circadian rhythms during late winter, which is especially severe, to those in less arduous seaso…
Regression‐based prediction of net energy expenditure in children performing activities at high altitude
We developed a simple, non-invasive, and affordable method for estimating net energy expenditure (EE) in children performing activities at high altitude. A regression-based method predicts net oxygen consumption (VO(2)) from net heart rate (HR) along with several covariates. The method is atypical in that, the "net" measures are taken as the difference between exercise and resting VO(2) (DeltaVO(2)) and the difference between exercise and resting…
Epidemiological transitions, reproductive health, and the Flexible Response Model
Higher arterial oxygen saturation during submaximal exercise in Bolivian Aymara compared to European sojourners and Europeans born and raised at high altitude
Arterial oxygen saturation (SaO2) was measured at 3,600–3,850 m by pulse oximetry at rest and during submaximal exercise in three study groups: 1) highland Aymara natives of the Bolivian altiplano (n = 25); 2) lowland European/North American sojourners to the highlands with at least 2 months of acclimatization time to 3,600 m (n = 27); and 3) subjects of European ancestry born and raised at 3,600 m (n = 22). Aymara subjects maintained ∼1 percenta…
Higher arterial oxygen saturation during submaximal exercise in Bolivian Aymara compared to European sojourners and Europeans born and raised at high altitude
Arterial oxygen saturation (SaO(2)) was measured at 3,600-3,850 m by pulse oximetry at rest and during submaximal exercise in three study groups: 1) highland Aymara natives of the Bolivian altiplano (n = 25); 2) lowland European/North American sojourners to the highlands with at least 2 months of acclimatization time to 3,600 m (n = 27); and 3) subjects of European ancestry born and raised at 3,600 m (n = 22). Aymara subjects maintained approxima…
Effect of developmental and ancestral high altitude exposure on chest morphology and pulmonary function in Andean and European/North American natives
Chest depth, chest width, forced vital capacity (FVC), and forced expiratory volume (FEV1) were measured in 170 adult males differing by ancestral (genetic) and developmental exposure to high altitude (HA). A complete migrant study design was used to study HA natives (Aymara/Quechua ancestry, n = 88) and low altitude (LA) natives (European/North American ancestry, n = 82) at both altitude (La Paz, Bolivia, 3,600 m) and near sea level (Santa Cruz,…
Effect of developmental and ancestral high-altitude exposure on ??O2peak of Andean and European/North American Natives
Peak oxygen consumption (VO(2)peak) was measured in 150 adult males (18-35 years old) in Bolivia, using a complete migrant study design to partition developmental from ancestral (genetic) effects of high-altitude (HA) exposure. High-altitude natives (HANs, Aymara/Quechua ancestry, n = 75) and low-altitude natives (LANs, European/North American ancestry, n = 75) were studied at high altitude (3,600-3,850 m) and near sea level (420 m). HAN and LAN …
Coca chewing among high altitude natives
The leaves of the coca plant ( Erythroxylum sp. ) have long been chewed by natives of the highland Andes. Folk belief is that the mild stimulant effect is indispensable as an ergogenic aid for strenuous work activities in a high altitude environment. This study explored the exercise responses of 23 nonhabitual coca chewing males who were asked to pedal a bicycle ergometer through a series of submaximal and maximal workloads both with and without …
Developmental, genetic, and environmental components of aerobic capacity at high altitude
The aerobic capacity of 268 subjects (158 males and 110 females) was evaluated in La Paz, Bolivia situated at 3,750 m. The sample included 1) 39 high altitude rural natives (all male); 2) 67 high altitude urban natives (32 male, 35 female); 3) 69 Bolivians of foreign ancestry acclimatized to high altitude since birth (37 male, 32 female); 4) 50 Bolivians of foreign ancestry acclimatized to high altitude during growth (25 male, 25 female); and 5) …
The importance of socioeconomic and nutritional conditions rather than altitude on the physical growth of prepubertal Andean highland boys
The aim of this work was to study the effect of hypoxic stress on the physical growth of prepubertal Bolivian boys (10-11.5 years of age) of the same socioeconomic and nutritional conditions. The subjects consisted of 143 boys living in La Paz (altitude 3600 m, n = 67) and Santa Cruz de la Sierra (altitude 420 m, n = 76). Among the boys studied at high altitude, 23 were from a high socioeconomic background (HA1) and 44 from a low socioeconomic ba…
Total lung capacity in young highlanders of Aymara ancestry
Total lung capacity (TLC) and its components, including residual volume (RV) and vital capacity (VC), are described in a sample of 164 male and 143 female youths of Aymara ancestry (10.0–19.9 years) who were born and raised at high altitudes (> 2,500 m) and who were residing in La Paz, Bolivia (average altitude of about 3,600 m). The hypothesis was tested that the enhanced lung volumes of adult highlanders are attained during the period of growth…
Maximal aerobic power in high-altitude runners
Maximal aerobic power (VO2max) was assessed in seven male and one female middle- and long-distance recreational runners residing in La Paz, Bolivia (3600 m). All runners were born and raised at high altitudes (> 2500). Mean VO2max in the male runners was 60.8 ml/kg/min while VO2max in the female runner was 55.5 ml/kg/min. These values are higher than in any previously reported sample of either trained or untrained high-altitude natives. In additi…
Skin reflectance of children and young adults of Aymara ancestry
The skin reflectance of 556 Andean Indians of Aymara ancestry (305 males, 251 females; 10.0–29.9 yr) residing in La Paz, Bolivia (average altitude of about 3,600 m) is described. Reflectances were measured at three wavelengths (425 nm, 545 nm, and 685 nm) on two different sites, the medial surface of the upper arm and forehead. Males tended to be significantly darker than females on both the upper arm and forehead ( P P
Effect of altitude on the lung function of high altitude residents of European ancestry
The forced vital capacity (FVC), forced expiratory volume in one second (FEV), and ratio of FEV to FVC (%FEV) of 161 male and 158 female youths of European ancestry who were born at high altitudes and who were residing in La Paz, Bolivia (average altitude of 3,600 m) were examined and compared with those for lowland Europeans and highland Aymara Amerindians. FVC and FEV were significantly larger (p
Lung function of young Aymara highlanders
The patterns of development of FVC, FEV and %FEV are examined in 217 male and 195 female youths of Aymara ancestry residing in La Paz, Bolivia (altitude 3600 m). The data provide some evidence of an acceleration in the development of lung function relative to stature in Aymara children, beginning during early adolescence, and also indicate that there is a strong relationship between lung function and chest dimensions in Aymara children. Similar p…
Effect of altitude on the physical growth of upper-class children of European ancestry
The physical growth of 351 upper-socioeconomic-status children (9-20 years) of European ancestry residing in La Paz, Bolivia (altitude 3600 m) is described and compared with that of lowland children of similar background. The purpose is to evaluate the independent effect of continual exposure to atmospheric hypoxia during the period of growth and development on linear growth. The data presented here indicate that the effect of hypoxia on achieved…
Maximal exercise capacity in adolescent European and Amerindian high‐altitude natives
Forty‐seven highland natives were given maximal exercise tests on a treadmill ergometer at 3,600 m. The subjects were grouped into four subsamples on the basis of ethnicity (European vs. Aymara) and age (young vs. old adolescent). Two‐way ANOVA indicated that VO 2 max adjusted for body size did not differ significantly between ethnic groups but was significantly larger in older than younger boys within each ethnic group (p 2 max's of highlanders …
Work performance of high-altitude Aymara males
The sample for this study consisted of 28 Aymara males between the ages of 15 and 43 years. The subjects were rural high-altitude natives who were temporarily working as porters in La Paz, Bolivia (3700 m). Mean VO2max was 46 X 5 ml/kg/min. There was a significant negative relationship between VO2max and age in adult porters . However, there was also a significant positive relationship between maximal work output and age and a significant negativ…
The physical growth of urban children at high altitude
The physical growth of urban Aymara children residing in La Paz, Bolivia (3,600 m) is described and compared with Amerindian children residing at low and high altitudes and with low‐altitude U.S. children. The sample consists of 227 males (10.6–19.7 yr) and 219 females (11.2–19.8 yr). The urban La Paz children were taller at all ages than rural high altitude Amerindian children but similar in stature to urban high altitude children from Peru. The…
Maximal aerobic power in trained youths at high altitude
The sample for this study consisted of 25 males and 19 females between the ages of 8.8 and 19.5 years. The subjects were healthy, well nourished and trained swimmers residing in La Paz, Bolivia (mean altitude 3700 m). The purpose of this study was to provide normative values for the work capacity of high-altitude youths. Mean VO2 max was 46.9 ml/kg/min in males and 39.3 ml/kg/min in females. VO2max increased significantly with age in males but no…
The physical growth of urban children at high altitude
The physical growth of urban Aymara children residing in La Paz, Bolivia (3,600 m) is described and compared with Amerindian children residing at low and high altitudes and with low‐altitude U.S. children. The sample consists of 227 males (10.6–19.7 yr) and 219 females (11.2–19.8 yr). The urban La Paz children were taller at all ages than rural high altitude Amerindian children but similar in stature to urban high altitude children from Peru. The…
Developmental, genetic, and environmental components of aerobic capacity at high altitude
The aerobic capacity of 268 subjects (158 males and 110 females) was evaluated in La Paz, Bolivia situated at 3,750 m. The sample included 1) 39 high altitude rural natives (all male); 2) 67 high altitude urban natives (32 male, 35 female); 3) 69 Bolivians of foreign ancestry acclimatized to high altitude since birth (37 male, 32 female); 4) 50 Bolivians of foreign ancestry acclimatized to high altitude during growth (25 male, 25 female); and 5) …
Effect of altitude on the lung function of high altitude residents of European ancestry
The forced vital capacity (FVC), forced expiratory volume in one second (FEV), and ratio of FEV to FVC (%FEV) of 161 male and 158 female youths of European ancestry who were born at high altitudes and who were residing in La Paz, Bolivia (average altitude of 3,600 m) were examined and compared with those for lowland Europeans and highland Aymara Amerindians. FVC and FEV were significantly larger (p
Maximal exercise capacity in adolescent European and Amerindian high‐altitude natives
Forty‐seven highland natives were given maximal exercise tests on a treadmill ergometer at 3,600 m. The subjects were grouped into four subsamples on the basis of ethnicity (European vs. Aymara) and age (young vs. old adolescent). Two‐way ANOVA indicated that VO 2 max adjusted for body size did not differ significantly between ethnic groups but was significantly larger in older than younger boys within each ethnic group (p 2 max's of highlanders …
Total lung capacity in young highlanders of Aymara ancestry
Total lung capacity (TLC) and its components, including residual volume (RV) and vital capacity (VC), are described in a sample of 164 male and 143 female youths of Aymara ancestry (10.0–19.9 years) who were born and raised at high altitudes (> 2,500 m) and who were residing in La Paz, Bolivia (average altitude of about 3,600 m). The hypothesis was tested that the enhanced lung volumes of adult highlanders are attained during the period of growth…
Maximal aerobic power in trained youths at high altitude
The sample for this study consisted of 25 males and 19 females between the ages of 8.8 and 19.5 years. The subjects were healthy, well nourished and trained swimmers residing in La Paz, Bolivia (mean altitude 3700 m). The purpose of this study was to provide normative values for the work capacity of high-altitude youths. Mean VO2 max was 46.9 ml/kg/min in males and 39.3 ml/kg/min in females. VO2max increased significantly with age in males but no…
Work performance of high-altitude Aymara males
The sample for this study consisted of 28 Aymara males between the ages of 15 and 43 years. The subjects were rural high-altitude natives who were temporarily working as porters in La Paz, Bolivia (3700 m). Mean VO2max was 46 X 5 ml/kg/min. There was a significant negative relationship between VO2max and age in adult porters . However, there was also a significant positive relationship between maximal work output and age and a significant negativ…
The physical growth of urban children at high altitude
The physical growth of urban Aymara children residing in La Paz, Bolivia (3,600 m) is described and compared with Amerindian children residing at low and high altitudes and with low‐altitude U.S. children. The sample consists of 227 males (10.6–19.7 yr) and 219 females (11.2–19.8 yr). The urban La Paz children were taller at all ages than rural high altitude Amerindian children but similar in stature to urban high altitude children from Peru. The…
Effect of altitude on the physical growth of upper-class children of European ancestry
The physical growth of 351 upper-socioeconomic-status children (9-20 years) of European ancestry residing in La Paz, Bolivia (altitude 3600 m) is described and compared with that of lowland children of similar background. The purpose is to evaluate the independent effect of continual exposure to atmospheric hypoxia during the period of growth and development on linear growth. The data presented here indicate that the effect of hypoxia on achieved…
Maximal exercise capacity in adolescent European and Amerindian high‐altitude natives
Forty‐seven highland natives were given maximal exercise tests on a treadmill ergometer at 3,600 m. The subjects were grouped into four subsamples on the basis of ethnicity (European vs. Aymara) and age (young vs. old adolescent). Two‐way ANOVA indicated that VO 2 max adjusted for body size did not differ significantly between ethnic groups but was significantly larger in older than younger boys within each ethnic group (p 2 max's of highlanders …
Lung function of young Aymara highlanders
The patterns of development of FVC, FEV and %FEV are examined in 217 male and 195 female youths of Aymara ancestry residing in La Paz, Bolivia (altitude 3600 m). The data provide some evidence of an acceleration in the development of lung function relative to stature in Aymara children, beginning during early adolescence, and also indicate that there is a strong relationship between lung function and chest dimensions in Aymara children. Similar p…
Effect of altitude on the lung function of high altitude residents of European ancestry
The forced vital capacity (FVC), forced expiratory volume in one second (FEV), and ratio of FEV to FVC (%FEV) of 161 male and 158 female youths of European ancestry who were born at high altitudes and who were residing in La Paz, Bolivia (average altitude of 3,600 m) were examined and compared with those for lowland Europeans and highland Aymara Amerindians. FVC and FEV were significantly larger (p
Skin reflectance of children and young adults of Aymara ancestry
The skin reflectance of 556 Andean Indians of Aymara ancestry (305 males, 251 females; 10.0–29.9 yr) residing in La Paz, Bolivia (average altitude of about 3,600 m) is described. Reflectances were measured at three wavelengths (425 nm, 545 nm, and 685 nm) on two different sites, the medial surface of the upper arm and forehead. Males tended to be significantly darker than females on both the upper arm and forehead ( P P
Maximal aerobic power in high-altitude runners
Maximal aerobic power (VO2max) was assessed in seven male and one female middle- and long-distance recreational runners residing in La Paz, Bolivia (3600 m). All runners were born and raised at high altitudes (> 2500). Mean VO2max in the male runners was 60.8 ml/kg/min while VO2max in the female runner was 55.5 ml/kg/min. These values are higher than in any previously reported sample of either trained or untrained high-altitude natives. In additi…
The importance of socioeconomic and nutritional conditions rather than altitude on the physical growth of prepubertal Andean highland boys
The aim of this work was to study the effect of hypoxic stress on the physical growth of prepubertal Bolivian boys (10-11.5 years of age) of the same socioeconomic and nutritional conditions. The subjects consisted of 143 boys living in La Paz (altitude 3600 m, n = 67) and Santa Cruz de la Sierra (altitude 420 m, n = 76). Among the boys studied at high altitude, 23 were from a high socioeconomic background (HA1) and 44 from a low socioeconomic ba…
Total lung capacity in young highlanders of Aymara ancestry
Total lung capacity (TLC) and its components, including residual volume (RV) and vital capacity (VC), are described in a sample of 164 male and 143 female youths of Aymara ancestry (10.0–19.9 years) who were born and raised at high altitudes (> 2,500 m) and who were residing in La Paz, Bolivia (average altitude of about 3,600 m). The hypothesis was tested that the enhanced lung volumes of adult highlanders are attained during the period of growth…
Coca chewing among high altitude natives
The leaves of the coca plant ( Erythroxylum sp. ) have long been chewed by natives of the highland Andes. Folk belief is that the mild stimulant effect is indispensable as an ergogenic aid for strenuous work activities in a high altitude environment. This study explored the exercise responses of 23 nonhabitual coca chewing males who were asked to pedal a bicycle ergometer through a series of submaximal and maximal workloads both with and without …
Developmental, genetic, and environmental components of aerobic capacity at high altitude
The aerobic capacity of 268 subjects (158 males and 110 females) was evaluated in La Paz, Bolivia situated at 3,750 m. The sample included 1) 39 high altitude rural natives (all male); 2) 67 high altitude urban natives (32 male, 35 female); 3) 69 Bolivians of foreign ancestry acclimatized to high altitude since birth (37 male, 32 female); 4) 50 Bolivians of foreign ancestry acclimatized to high altitude during growth (25 male, 25 female); and 5) …
Effect of developmental and ancestral high altitude exposure on chest morphology and pulmonary function in Andean and European/North American natives
Chest depth, chest width, forced vital capacity (FVC), and forced expiratory volume (FEV1) were measured in 170 adult males differing by ancestral (genetic) and developmental exposure to high altitude (HA). A complete migrant study design was used to study HA natives (Aymara/Quechua ancestry, n = 88) and low altitude (LA) natives (European/North American ancestry, n = 82) at both altitude (La Paz, Bolivia, 3,600 m) and near sea level (Santa Cruz,…
Effect of developmental and ancestral high-altitude exposure on ??O2peak of Andean and European/North American Natives
Peak oxygen consumption (VO(2)peak) was measured in 150 adult males (18-35 years old) in Bolivia, using a complete migrant study design to partition developmental from ancestral (genetic) effects of high-altitude (HA) exposure. High-altitude natives (HANs, Aymara/Quechua ancestry, n = 75) and low-altitude natives (LANs, European/North American ancestry, n = 75) were studied at high altitude (3,600-3,850 m) and near sea level (420 m). HAN and LAN …
Higher arterial oxygen saturation during submaximal exercise in Bolivian Aymara compared to European sojourners and Europeans born and raised at high altitude
Arterial oxygen saturation (SaO2) was measured at 3,600–3,850 m by pulse oximetry at rest and during submaximal exercise in three study groups: 1) highland Aymara natives of the Bolivian altiplano (n = 25); 2) lowland European/North American sojourners to the highlands with at least 2 months of acclimatization time to 3,600 m (n = 27); and 3) subjects of European ancestry born and raised at 3,600 m (n = 22). Aymara subjects maintained ∼1 percenta…
Higher arterial oxygen saturation during submaximal exercise in Bolivian Aymara compared to European sojourners and Europeans born and raised at high altitude
Arterial oxygen saturation (SaO(2)) was measured at 3,600-3,850 m by pulse oximetry at rest and during submaximal exercise in three study groups: 1) highland Aymara natives of the Bolivian altiplano (n = 25); 2) lowland European/North American sojourners to the highlands with at least 2 months of acclimatization time to 3,600 m (n = 27); and 3) subjects of European ancestry born and raised at 3,600 m (n = 22). Aymara subjects maintained approxima…
Regression‐based prediction of net energy expenditure in children performing activities at high altitude
We developed a simple, non-invasive, and affordable method for estimating net energy expenditure (EE) in children performing activities at high altitude. A regression-based method predicts net oxygen consumption (VO(2)) from net heart rate (HR) along with several covariates. The method is atypical in that, the "net" measures are taken as the difference between exercise and resting VO(2) (DeltaVO(2)) and the difference between exercise and resting…
Epidemiological transitions, reproductive health, and the Flexible Response Model
Seasonal modulation of reproductive effort during early pregnancy in humans
Life history theory predicts that early pregnancy presents a relatively low cost, uncontested opportunity for a woman to terminate investment in a current reproductive opportunity if a conceptus is of poor quality and/or maternal status or environmental conditions are not propitious for a successful birth. We tested this hypothesis in rural Bolivian women experiencing substantial seasonal variation in workload and food resources. Significant risk…
Seasonal and circadian variation in salivary testosterone in rural Bolivian men
Testosterone (T) plays a key role in the increase and maintenance of muscle mass and bone density in adult men. Life history theory predicts that environmental stress may prompt a reallocation of such investments to those functions critical to survival. We tested this hypothesis in two studies of rural Bolivian adult men by comparing free T levels and circadian rhythms during late winter, which is especially severe, to those in less arduous seaso…
Recognizing normal reproductive biology
The idealized "normal" menstrual cycle typically comprises a coordinated ebb and flow of hormones over a 28-day span with ovulation invariably shown at the midpoint. It's a pretty picture-but rare. Systematic studies have debunked the myth that cycles occur regularly about every 28 days. However, assumptions persist regarding the extent and normalcy of variation in other cycle biomarkers. The processes of judging which phenotypic variants are "no…
C‐reactive protein (CRP) in high altitude Bolivian peri‐urban adolescents varies by adiposity, current illness, height, socioeconomic status, sex, and menarcheal status
OBJECTIVES: In non-industrialized and low-income populations, adipose stores can serve as a valuable buffer against harsh conditions such as seasonal food scarcity. However, these reserves may incur costs due to adipocytes' production of pro-inflammatory cytokines; inflammation is associated with increased risk for cardiometabolic diseases later in life. Life history theory posits that, especially in populations with high juvenile mortality, high…
Demography (21 obras) · Medicine (20 obras) · Internal Medicine (15 obras) · Effects of high altitude on humans (12 obras) · High Altitude and Hypoxia (11 obras) · Biology (9 obras) · Geography (9 obras) · Anatomy (8 obras) · Blood pressure (8 obras) · Heart rate (8 obras)