Yann C Klimentidis
Biographic Data
| ID | 4292231 |
|---|---|
| NAME | Yann C Klimentidis |
| GIVEN NAMES | Yann C |
| FAMILY NAME | Klimentidis |
| SIGNATURE | KLIMENTIDIS Y C |
| AFFILIATIONS | University of Arizona |
| ORCID | 0000-0002-6065-4044 |
| VERIFIED | Yes |
| TOTAL WORKS | 8 |
| TOTAL CITATIONS | 13 |
| WORKS AS AUTHOR | 8 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2009 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 2 |
Nonlinear Associations of Accelerometer-Based Sedentary Time With Cognitive Functions in the UK Biobank
Objectives Device-based sedentary time shows a nonlinear association with incident dementia among older adults. However, associations between sedentary time and cognitive performance have been inconsistent. We examined potential nonlinear associations between sedentary time and performance on cognitive tests among older adults. Methods We used data from the UK Biobank and included 32,875 adults aged 60–79. Sedentary time was estimated from a mach…
Design of the Arizona CoVHORT
This study is a prospective, population-based cohort of individuals with a history of SARS-CoV-2 infection and those without past infection through multiple recruitment sources. The main study goal is to track health status over time, within the diverse populations of Arizona and to identify the long-term consequences of COVID-19 on health and well-being. A total of 2,881 study participants (16.2% with a confirmed SARS-CoV-2 infection) have been …
Assessing Interactions between PNPLA3 and Dietary Intake on Liver Steatosis in Mexican-Origin Adults
Mexican-origin (MO) adults have among the highest rates of nonalcoholic fatty liver disease (NAFLD) placing them at increased risk of liver cancer. Evidence suggests that a single nucleotide polymorphism (SNP) in the PNPLA3 gene, rs738409, increases the risk and progression of NAFLD and may modify the relationship between certain dietary factors and liver steatosis. The purpose of this study was to identify whether interactions exist between spec…
The intersectional role of social stress in fracture risk
BACKGROUND: The biological consequences of stress from the social environment pattern health outcomes. This study investigated whether social stress is prospectively associated with fracture incidence among racially and ethnically diverse, postmenopausal women. METHODS: Data from 160 709 postmenopausal women in the Women's Health Initiative was analysed using Cox proportional hazards regression models to examine prospective associations of social…
Psychosocial stress and bone loss among postmenopausal women
BACKGROUND: Bone loss is a major public health concern with large proportions of older women experiencing osteoporotic fractures. Previous research has established a relationship between psychosocial stressors and fractures. However, few studies have investigated bone loss as an intermediary in this relationship. This study investigates whether social stress is associated with bone loss during a 6-year period in postmenopausal women. METHODS: Dat…
Evidence for novel genetic loci associated with metabolic traits in Yup'ik people
OBJECTIVES: To identify genomic regions associated with fasting plasma lipid profiles, insulin, glucose, and glycosylated hemoglobin in a Yup'ik study population, and to evaluate whether the observed associations between genetic factors and metabolic traits were modified by dietary intake of marine derived omega-3 polyunsaturated acids (n-3 PUFA). METHODS: A genome-wide linkage scan was conducted among 982 participants of the Center for Alaska Na…
The relationship between European genetic admixture and body composition among Hispanics and Native Americans
Previous studies have shown a relationship between health-related phenotypes and the degree of African, European, or Native American genetic admixture, indicating that there may be a genetic component to these phenotypes. However, these relationships may be driven to a large extent by the environmental differences that co-vary with admixture differences between and within groups. In this study, we examine the relationship between genetic admixtur…
Genetic admixture, self‐reported ethnicity, self‐estimated admixture, and skin pigmentation among Hispanics and Native Americans
The relationship between ethnicity and biology is of interest to anthropologists, biomedical scientists, and historians in understanding how human groups are constructed. Ethnic self‐identification in recently admixed groups such as Hispanics, African Americans, and Native Americans (NA) is likely to be complex due to the heterogeneity in individual admixture proportions and social environments within these groups. This study examines the relatio…
Genetic admixture, self‐reported ethnicity, self‐estimated admixture, and skin pigmentation among Hispanics and Native Americans
The relationship between ethnicity and biology is of interest to anthropologists, biomedical scientists, and historians in understanding how human groups are constructed. Ethnic self‐identification in recently admixed groups such as Hispanics, African Americans, and Native Americans (NA) is likely to be complex due to the heterogeneity in individual admixture proportions and social environments within these groups. This study examines the relatio…
Psychosocial stress and bone loss among postmenopausal women
BACKGROUND: Bone loss is a major public health concern with large proportions of older women experiencing osteoporotic fractures. Previous research has established a relationship between psychosocial stressors and fractures. However, few studies have investigated bone loss as an intermediary in this relationship. This study investigates whether social stress is associated with bone loss during a 6-year period in postmenopausal women. METHODS: Dat…
The relationship between European genetic admixture and body composition among Hispanics and Native Americans
Previous studies have shown a relationship between health-related phenotypes and the degree of African, European, or Native American genetic admixture, indicating that there may be a genetic component to these phenotypes. However, these relationships may be driven to a large extent by the environmental differences that co-vary with admixture differences between and within groups. In this study, we examine the relationship between genetic admixtur…
Genetic admixture, self‐reported ethnicity, self‐estimated admixture, and skin pigmentation among Hispanics and Native Americans
The relationship between ethnicity and biology is of interest to anthropologists, biomedical scientists, and historians in understanding how human groups are constructed. Ethnic self‐identification in recently admixed groups such as Hispanics, African Americans, and Native Americans (NA) is likely to be complex due to the heterogeneity in individual admixture proportions and social environments within these groups. This study examines the relatio…
Evidence for novel genetic loci associated with metabolic traits in Yup'ik people
OBJECTIVES: To identify genomic regions associated with fasting plasma lipid profiles, insulin, glucose, and glycosylated hemoglobin in a Yup'ik study population, and to evaluate whether the observed associations between genetic factors and metabolic traits were modified by dietary intake of marine derived omega-3 polyunsaturated acids (n-3 PUFA). METHODS: A genome-wide linkage scan was conducted among 982 participants of the Center for Alaska Na…
Psychosocial stress and bone loss among postmenopausal women
BACKGROUND: Bone loss is a major public health concern with large proportions of older women experiencing osteoporotic fractures. Previous research has established a relationship between psychosocial stressors and fractures. However, few studies have investigated bone loss as an intermediary in this relationship. This study investigates whether social stress is associated with bone loss during a 6-year period in postmenopausal women. METHODS: Dat…
Design of the Arizona CoVHORT
This study is a prospective, population-based cohort of individuals with a history of SARS-CoV-2 infection and those without past infection through multiple recruitment sources. The main study goal is to track health status over time, within the diverse populations of Arizona and to identify the long-term consequences of COVID-19 on health and well-being. A total of 2,881 study participants (16.2% with a confirmed SARS-CoV-2 infection) have been …
Assessing Interactions between PNPLA3 and Dietary Intake on Liver Steatosis in Mexican-Origin Adults
Mexican-origin (MO) adults have among the highest rates of nonalcoholic fatty liver disease (NAFLD) placing them at increased risk of liver cancer. Evidence suggests that a single nucleotide polymorphism (SNP) in the PNPLA3 gene, rs738409, increases the risk and progression of NAFLD and may modify the relationship between certain dietary factors and liver steatosis. The purpose of this study was to identify whether interactions exist between spec…
The intersectional role of social stress in fracture risk
BACKGROUND: The biological consequences of stress from the social environment pattern health outcomes. This study investigated whether social stress is prospectively associated with fracture incidence among racially and ethnically diverse, postmenopausal women. METHODS: Data from 160 709 postmenopausal women in the Women's Health Initiative was analysed using Cox proportional hazards regression models to examine prospective associations of social…
Nonlinear Associations of Accelerometer-Based Sedentary Time With Cognitive Functions in the UK Biobank
Objectives Device-based sedentary time shows a nonlinear association with incident dementia among older adults. However, associations between sedentary time and cognitive performance have been inconsistent. We examined potential nonlinear associations between sedentary time and performance on cognitive tests among older adults. Methods We used data from the UK Biobank and included 32,875 adults aged 60–79. Sedentary time was estimated from a mach…
Medicine (8 works) · Biology (5 works) · Gene (4 works) · Genetics (4 works) · Internal Medicine (4 works) · Population (4 works) · Demography (3 works) · Ethnic group (3 works) · Genotype (3 works) · Gerontology (3 works)