Shigekazu Higuchi
Biographic Data
| ID | 4306993 |
|---|---|
| NAME | Shigekazu Higuchi |
| GIVEN NAMES | Shigekazu |
| FAMILY NAME | Higuchi |
| SIGNATURE | HIGUCHI S |
| AFFILIATIONS | Kyushu University |
| ORCID | 0000-0001-7131-0792 |
| VERIFIED | Yes |
| TOTAL WORKS | 10 |
| TOTAL CITATIONS | 12 |
| AUTHOR COUNT | 10 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2007 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 2 |
Acute hypobaric hypoxia induces coordinated DNA methylation alterations and immune cell redistribution in lowlanders
Background: Acute hypobaric hypoxia rapidly affects oxygen transport, endocrine regulation, and immune function. However, how short-term hypoxic stress links immune cell redistribution with changes in blood DNA methylation remains unclear. Objectives: We aimed to characterize coordinated immune and DNA methylation responses to acute hypobaric hypoxia in lowlanders and to distinguish methylation changes caused by altered blood cell composition fro…
Light at night and circadian rhythms: From the Perspective of Physiological Anthropology Research
Effects of observing own/others hand movement in different perspectives on mu rhythm suppression: An EEG study
Background Previous studies have reported that the sense of "self" is associated with specific brain regions and neural network activities. In addition, the mirror system, which functions when executing or observing an action, might contribute to differentiating the self from others and form the basis of the sense of self as a fundamental physical representation. This study investigated whether differences in mu suppression, an indicator of mirro…
Effects of others' gaze and facial expression on an observer's microsaccades and their association with ADHD tendencies
Background The aim of this study was to examine the effect of others' gaze on an observer's microsaccades. We also aimed to conduct preliminary investigations on the relationship between the microsaccadic response to a gaze and a gazer's facial expression and attention-deficit/hyperactivity disorder (ADHD) tendencies. Methods Twenty healthy undergraduate and graduate students performed a peripheral target detection task by using unpredictable gaz…
Effects of bathing-induced changes in body temperature on sleep
Background Passive body heating before sleep is well known to lead to improved sleep. However, the effects of the degree of change in body temperature by bathing on sleep quality are unclear. The present study aimed to clarify the effects on sleep of bathing-induced changes in body temperature. Methods Twenty-three healthy males and females in their 20 s to 50 s bathed in their homes 1.5-2 h before bedtime under three bathing conditions: showerin…
Circadian phase advances in children during camping life according to the natural light-dark cycle
Background It is known that the circadian rhythm phase in adults can be advanced in a natural light-dark cycle without electrical lighting. However, the effect of advanced sleep-wake timing according to the natural light-dark cycle on children's circadian phase is unclear. We investigated the effects of approximately 2 weeks of camping life with little access to artificial lighting on children's circadian phases. We also conducted an exploratory …
Intake of l-serine before bedtime prevents the delay of the circadian phase in real life
Background It has been shown in laboratory experiments using human subjects that ingestion of the non-essential amino acid l-serine before bedtime enhances the advance of circadian phase induced by light exposure the next morning. In the present study, we tested the effect of ingestion of l-serine before bedtime on circadian phase in real life and whether its effect depends on the initial circadian phase. Methods The subjects were 33 healthy male…
Is the use of high correlated color temperature light at night related to delay of sleep timing in university students? A cross-country study in Japan and China
BackgroundBlue-enriched white light at night has the potential to delay the circadian rhythm in daily life. This study was conducted to determine whether the use of high correlated color temperature (CCT) light at home at night is associated with delay of sleep timing in university students.MethodsThe survey was conducted in 2014-2015 in 447 university students in Japan and 327 students in China. Habitual sleep timing and type of CCT light at hom…
Effectiveness of a Red-visor Cap for Preventing Light-induced Melatonin Suppression during Simulated Night Work
Bright light at night improves the alertness of night workers. Melatonin suppression induced by light at night is, however, reported to be a possible risk factor for breast cancer. Short-wavelength light has a strong impact on melatonin suppression. A red-visor cap can cut the short-wavelength light from the upper visual field selectively with no adverse effects on visibility. The purpose of this study was to investigate the effects of a red-viso…
Involvement of Basal Metabolic Rate in Determination of Type of Cold Tolerance
This study aimed to assess the relationship between basal metabolic rate (BMR) and metabolic heat production, and to clarify the involvement of BMR in determining the phenotype of cold tolerance. Measurements of BMR, maximum oxygen uptake, and cold exposure test were conducted on ten males. In the cold exposure test, rectal (T(rec)) and mean skin temperatures (T(ms)), oxygen uptake, and blood flow at forearm (BF(arm)) were measured during exposur…
Is the use of high correlated color temperature light at night related to delay of sleep timing in university students? A cross-country study in Japan and China
BackgroundBlue-enriched white light at night has the potential to delay the circadian rhythm in daily life. This study was conducted to determine whether the use of high correlated color temperature (CCT) light at home at night is associated with delay of sleep timing in university students.MethodsThe survey was conducted in 2014-2015 in 447 university students in Japan and 327 students in China. Habitual sleep timing and type of CCT light at hom…
Circadian phase advances in children during camping life according to the natural light-dark cycle
Background It is known that the circadian rhythm phase in adults can be advanced in a natural light-dark cycle without electrical lighting. However, the effect of advanced sleep-wake timing according to the natural light-dark cycle on children's circadian phase is unclear. We investigated the effects of approximately 2 weeks of camping life with little access to artificial lighting on children's circadian phases. We also conducted an exploratory …
Intake of l-serine before bedtime prevents the delay of the circadian phase in real life
Background It has been shown in laboratory experiments using human subjects that ingestion of the non-essential amino acid l-serine before bedtime enhances the advance of circadian phase induced by light exposure the next morning. In the present study, we tested the effect of ingestion of l-serine before bedtime on circadian phase in real life and whether its effect depends on the initial circadian phase. Methods The subjects were 33 healthy male…
Involvement of Basal Metabolic Rate in Determination of Type of Cold Tolerance
This study aimed to assess the relationship between basal metabolic rate (BMR) and metabolic heat production, and to clarify the involvement of BMR in determining the phenotype of cold tolerance. Measurements of BMR, maximum oxygen uptake, and cold exposure test were conducted on ten males. In the cold exposure test, rectal (T(rec)) and mean skin temperatures (T(ms)), oxygen uptake, and blood flow at forearm (BF(arm)) were measured during exposur…
Effects of bathing-induced changes in body temperature on sleep
Background Passive body heating before sleep is well known to lead to improved sleep. However, the effects of the degree of change in body temperature by bathing on sleep quality are unclear. The present study aimed to clarify the effects on sleep of bathing-induced changes in body temperature. Methods Twenty-three healthy males and females in their 20 s to 50 s bathed in their homes 1.5-2 h before bedtime under three bathing conditions: showerin…
Effectiveness of a Red-visor Cap for Preventing Light-induced Melatonin Suppression during Simulated Night Work
Bright light at night improves the alertness of night workers. Melatonin suppression induced by light at night is, however, reported to be a possible risk factor for breast cancer. Short-wavelength light has a strong impact on melatonin suppression. A red-visor cap can cut the short-wavelength light from the upper visual field selectively with no adverse effects on visibility. The purpose of this study was to investigate the effects of a red-viso…
Involvement of Basal Metabolic Rate in Determination of Type of Cold Tolerance
This study aimed to assess the relationship between basal metabolic rate (BMR) and metabolic heat production, and to clarify the involvement of BMR in determining the phenotype of cold tolerance. Measurements of BMR, maximum oxygen uptake, and cold exposure test were conducted on ten males. In the cold exposure test, rectal (T(rec)) and mean skin temperatures (T(ms)), oxygen uptake, and blood flow at forearm (BF(arm)) were measured during exposur…
Effectiveness of a Red-visor Cap for Preventing Light-induced Melatonin Suppression during Simulated Night Work
Bright light at night improves the alertness of night workers. Melatonin suppression induced by light at night is, however, reported to be a possible risk factor for breast cancer. Short-wavelength light has a strong impact on melatonin suppression. A red-visor cap can cut the short-wavelength light from the upper visual field selectively with no adverse effects on visibility. The purpose of this study was to investigate the effects of a red-viso…
Is the use of high correlated color temperature light at night related to delay of sleep timing in university students? A cross-country study in Japan and China
BackgroundBlue-enriched white light at night has the potential to delay the circadian rhythm in daily life. This study was conducted to determine whether the use of high correlated color temperature (CCT) light at home at night is associated with delay of sleep timing in university students.MethodsThe survey was conducted in 2014-2015 in 447 university students in Japan and 327 students in China. Habitual sleep timing and type of CCT light at hom…
Circadian phase advances in children during camping life according to the natural light-dark cycle
Background It is known that the circadian rhythm phase in adults can be advanced in a natural light-dark cycle without electrical lighting. However, the effect of advanced sleep-wake timing according to the natural light-dark cycle on children's circadian phase is unclear. We investigated the effects of approximately 2 weeks of camping life with little access to artificial lighting on children's circadian phases. We also conducted an exploratory …
Intake of l-serine before bedtime prevents the delay of the circadian phase in real life
Background It has been shown in laboratory experiments using human subjects that ingestion of the non-essential amino acid l-serine before bedtime enhances the advance of circadian phase induced by light exposure the next morning. In the present study, we tested the effect of ingestion of l-serine before bedtime on circadian phase in real life and whether its effect depends on the initial circadian phase. Methods The subjects were 33 healthy male…
Effects of others' gaze and facial expression on an observer's microsaccades and their association with ADHD tendencies
Background The aim of this study was to examine the effect of others' gaze on an observer's microsaccades. We also aimed to conduct preliminary investigations on the relationship between the microsaccadic response to a gaze and a gazer's facial expression and attention-deficit/hyperactivity disorder (ADHD) tendencies. Methods Twenty healthy undergraduate and graduate students performed a peripheral target detection task by using unpredictable gaz…
Effects of bathing-induced changes in body temperature on sleep
Background Passive body heating before sleep is well known to lead to improved sleep. However, the effects of the degree of change in body temperature by bathing on sleep quality are unclear. The present study aimed to clarify the effects on sleep of bathing-induced changes in body temperature. Methods Twenty-three healthy males and females in their 20 s to 50 s bathed in their homes 1.5-2 h before bedtime under three bathing conditions: showerin…
Light at night and circadian rhythms: From the Perspective of Physiological Anthropology Research
Effects of observing own/others hand movement in different perspectives on mu rhythm suppression: An EEG study
Background Previous studies have reported that the sense of "self" is associated with specific brain regions and neural network activities. In addition, the mirror system, which functions when executing or observing an action, might contribute to differentiating the self from others and form the basis of the sense of self as a fundamental physical representation. This study investigated whether differences in mu suppression, an indicator of mirro…
Acute hypobaric hypoxia induces coordinated DNA methylation alterations and immune cell redistribution in lowlanders
Background: Acute hypobaric hypoxia rapidly affects oxygen transport, endocrine regulation, and immune function. However, how short-term hypoxic stress links immune cell redistribution with changes in blood DNA methylation remains unclear. Objectives: We aimed to characterize coordinated immune and DNA methylation responses to acute hypobaric hypoxia in lowlanders and to distinguish methylation changes caused by altered blood cell composition fro…
Medicine (8 works) · Psychology (7 works) · Circadian rhythm and melatonin (5 works) · Audiology (4 works) · Internal Medicine (4 works) · Sleep and related disorders (4 works) · Circadian rhythm (3 works) · Impact of Light on Environment and Health (3 works) · Melatonin (3 works) · Neuroscience (3 works)