Donald M Thea
Biographic Data
| ID | 4340697 |
|---|---|
| NAME | Donald M Thea |
| GIVEN NAMES | Donald M |
| FAMILY NAME | Thea |
| SIGNATURE | THEA D M |
| AFFILIATIONS | Boston University |
| ORCID | 0000-0002-6933-1030 |
| VERIFIED | Yes |
| TOTAL WORKS | 10 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 10 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1998 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Present or absent
Background: Despite a reduction in sudden unexplained infant death (SUID) in high-income countries, the incidence of SUID and the prevalence of its risk and protective factors remain poorly understood in Zambia due to limited research. We aimed to describe the infant sleep positions and sleep environments in an urban Zambian population to gain a better understanding of modifiable risk factors for SUID. Methods: We used antenatal, birth, and postn…
Development and validation of a novel clinical risk score to predict hypoxaemia in children with pneumonia using the WHO PREPARE dataset
BACKGROUND: Hypoxaemia predicts mortality at all levels of care, and appropriate management can reduce preventable deaths. However, pulse oximetry and oxygen therapy remain inaccessible in many primary care health facilities. We aimed to develop and validate a simple risk score comprising commonly evaluated clinical features to predict hypoxaemia in 2-59-month-old children with pneumonia. METHODS: Data from seven studies conducted in five countri…
Derivation and validation of a novel risk assessment tool to identify children aged 2–59 months at risk of hospitalised pneumonia-related mortality in 20 countries
INTRODUCTION: Existing risk assessment tools to identify children at risk of hospitalised pneumonia-related mortality have shown suboptimal discriminatory value during external validation. Our objective was to derive and validate a novel risk assessment tool to identify children aged 2-59 months at risk of hospitalised pneumonia-related mortality across various settings. METHODS: We used primary, baseline, patient-level data from 11 studies, incl…
Adherence to and enforcement of non-pharmaceutical interventions (NPIs) for Covid-19 prevention in Nigeria, Rwanda, and Zambia
Introduction In the early parts of the COVID-19 pandemic, non-pharmaceutical interventions (NPIs) were implemented worldwide, including in sub-Saharan Africa, to prevent and control SARS-CoV-2 transmission. This mixed-methods study examines adherence to and enforcement of NPIs implemented to curb COVID-19 in Nigeria, Rwanda, and Zambia, leading up to the 10,000 th case of laboratory-confirmed COVID-19 in each country. Additionally, we aim to eval…
Assembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm
Background: The existing World Health Organization (WHO) pneumonia case management guidelines rely on clinical symptoms and signs for identifying, classifying, and treating pneumonia in children up to 5 years old. We aimed to collate an individual patient-level data set from large, high-quality pre-existing studies on pneumonia in children to identify a set of signs and symptoms with greater validity in the diagnosis, prognosis, and possible trea…
External validation of the Risc, Risc-Malawi, and PERCH clinical prediction rules to identify risk of death in children hospitalized with pneumonia
BACKGROUND: Existing scores to identify children at risk of hospitalized pneumonia-related mortality lack broad external validation. Our objective was to externally validate three such risk scores. METHODS: We applied the Respiratory Index of Severity in Children (RISC) for HIV-negative children, the RISC-Malawi, and the Pneumonia Etiology Research for Child Health (PERCH) scores to hospitalized children in the Pneumonia REsearch Partnerships to …
The impact of a multi-level maternal health programme on facility delivery and capacity for emergency obstetric care in Zambia
In 2012, Saving Mothers, Giving Life (SMGL), a multi-level health systems initiative, launched in Kalomo District, Zambia, to address persistent challenges in reducing maternal mortality. We assessed the impact of the programme from 2012 to 2013 using a quasi-experimental study with both household- and health facility-level data collected before and after implementation in both intervention and comparison areas. A total of 21,680 women and 75 non…
Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women
Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors…
Relative and interacting effects of sex, race, and environment upon body cell mass in healthy adults
Most epidemiologic studies in nutrition have concentrated on body fat and obesity because of associated health risks, while few studies have examined factors that influence body cell mass (BCM). The relative influences of sex, race, environment, and age upon BCM were compared by analyzing the results of bioimpedance analyses in two cohorts of 1094 healthy adults, including Africans in Zaire, plus African Americans and Caucasians in New York City.…
Relative and interacting effects of sex, race, and environment upon body cell mass in healthy adults
Most epidemiologic studies in nutrition have concentrated on body fat and obesity because of associated health risks, while few studies have examined factors that influence body cell mass (BCM). The relative influences of sex, race, environment, and age upon BCM were compared by analyzing the results of bioimpedance analyses in two cohorts of 1094 healthy adults, including Africans in Zaire, plus African Americans and Caucasians in New York City.…
No prominent works on this page.
Relative and interacting effects of sex, race, and environment upon body cell mass in healthy adults
Most epidemiologic studies in nutrition have concentrated on body fat and obesity because of associated health risks, while few studies have examined factors that influence body cell mass (BCM). The relative influences of sex, race, environment, and age upon BCM were compared by analyzing the results of bioimpedance analyses in two cohorts of 1094 healthy adults, including Africans in Zaire, plus African Americans and Caucasians in New York City.…
Relative and interacting effects of sex, race, and environment upon body cell mass in healthy adults
Most epidemiologic studies in nutrition have concentrated on body fat and obesity because of associated health risks, while few studies have examined factors that influence body cell mass (BCM). The relative influences of sex, race, environment, and age upon BCM were compared by analyzing the results of bioimpedance analyses in two cohorts of 1094 healthy adults, including Africans in Zaire, plus African Americans and Caucasians in New York City.…
Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women
Sub-Saharan Africa contains over 60% of the world's HIV infections and Zambia is among the most severely affected countries in the region. As antiretroviral programs have been rapidly expanding, the long-term success of these programs depends on a good understanding of the behavioral determinants of acceptance and adherence to antiretroviral therapy (ART). The study used qualitative methods to gain local insight into potentially important factors…
The impact of a multi-level maternal health programme on facility delivery and capacity for emergency obstetric care in Zambia
In 2012, Saving Mothers, Giving Life (SMGL), a multi-level health systems initiative, launched in Kalomo District, Zambia, to address persistent challenges in reducing maternal mortality. We assessed the impact of the programme from 2012 to 2013 using a quasi-experimental study with both household- and health facility-level data collected before and after implementation in both intervention and comparison areas. A total of 21,680 women and 75 non…
External validation of the Risc, Risc-Malawi, and PERCH clinical prediction rules to identify risk of death in children hospitalized with pneumonia
BACKGROUND: Existing scores to identify children at risk of hospitalized pneumonia-related mortality lack broad external validation. Our objective was to externally validate three such risk scores. METHODS: We applied the Respiratory Index of Severity in Children (RISC) for HIV-negative children, the RISC-Malawi, and the Pneumonia Etiology Research for Child Health (PERCH) scores to hospitalized children in the Pneumonia REsearch Partnerships to …
Derivation and validation of a novel risk assessment tool to identify children aged 2–59 months at risk of hospitalised pneumonia-related mortality in 20 countries
INTRODUCTION: Existing risk assessment tools to identify children at risk of hospitalised pneumonia-related mortality have shown suboptimal discriminatory value during external validation. Our objective was to derive and validate a novel risk assessment tool to identify children aged 2-59 months at risk of hospitalised pneumonia-related mortality across various settings. METHODS: We used primary, baseline, patient-level data from 11 studies, incl…
Adherence to and enforcement of non-pharmaceutical interventions (NPIs) for Covid-19 prevention in Nigeria, Rwanda, and Zambia
Introduction In the early parts of the COVID-19 pandemic, non-pharmaceutical interventions (NPIs) were implemented worldwide, including in sub-Saharan Africa, to prevent and control SARS-CoV-2 transmission. This mixed-methods study examines adherence to and enforcement of NPIs implemented to curb COVID-19 in Nigeria, Rwanda, and Zambia, leading up to the 10,000 th case of laboratory-confirmed COVID-19 in each country. Additionally, we aim to eval…
Assembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm
Background: The existing World Health Organization (WHO) pneumonia case management guidelines rely on clinical symptoms and signs for identifying, classifying, and treating pneumonia in children up to 5 years old. We aimed to collate an individual patient-level data set from large, high-quality pre-existing studies on pneumonia in children to identify a set of signs and symptoms with greater validity in the diagnosis, prognosis, and possible trea…
Development and validation of a novel clinical risk score to predict hypoxaemia in children with pneumonia using the WHO PREPARE dataset
BACKGROUND: Hypoxaemia predicts mortality at all levels of care, and appropriate management can reduce preventable deaths. However, pulse oximetry and oxygen therapy remain inaccessible in many primary care health facilities. We aimed to develop and validate a simple risk score comprising commonly evaluated clinical features to predict hypoxaemia in 2-59-month-old children with pneumonia. METHODS: Data from seven studies conducted in five countri…
Present or absent
Background: Despite a reduction in sudden unexplained infant death (SUID) in high-income countries, the incidence of SUID and the prevalence of its risk and protective factors remain poorly understood in Zambia due to limited research. We aimed to describe the infant sleep positions and sleep environments in an urban Zambian population to gain a better understanding of modifiable risk factors for SUID. Methods: We used antenatal, birth, and postn…
Medicine (10 works) · Intensive care medicine (4 works) · Internal Medicine (4 works) · Pneumonia (4 works) · Pneumonia and Respiratory Infections (4 works) · Environmental health (3 works) · Logistic regression (3 works) · Pediatrics (3 works) · Psychology (3 works) · Advanced Causal Inference Techniques (2 works)