Caroline L Relton
Biographic Data
| ID | 4364672 |
|---|---|
| NAME | Caroline L Relton |
| GIVEN NAMES | Caroline L |
| FAMILY NAME | Relton |
| SIGNATURE | RELTON C L |
| AFFILIATIONS | Newcastle University |
| ORCID | 0000-0003-2052-4840 |
| VERIFIED | Yes |
| TOTAL WORKS | 5 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 5 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2005 |
| LATEST PUBLICATION YEAR | 2019 |
| H-INDEX | 0 |
Serum cholesterol, MTHFR methylation, and symptoms of depression in children
Depression is associated with dietary factors and epigenetics. Serum cholesterol, which is prone to dietary influences, has been linked to symptoms of depression. This relationship may be (in part) due to altered epigenetic regulation of Methylenetetrahydrofolate Reductase (MTHFR). MTHFR codes for the MTHFR enzyme, which has diverse metabolic functions, and has recently been linked individually with diet, serum cholesterol levels and depressive s…
Assessment of Offspring DNA Methylation across the Lifecourse Associated with Prenatal Maternal Smoking Using Bayesian Mixture Modelling
A growing body of research has implicated DNA methylation as a potential mediator of the effects of maternal smoking in pregnancy on offspring ill-health. Data were available from a UK birth cohort of children with DNA methylation measured at birth, age 7 and 17. One issue when analysing genome-wide DNA methylation data is the correlation of methylation levels between CpG sites, though this can be crudely bypassed using a data reduction method. I…
Birth weight and early socio‐economic disadvantage as predictors of sex hormones and sex hormone binding globulin in men at age 49–51 years
Objectives: A number of associations have been shown between early growth and later sex hormone levels in women, but less is known about this relationship in men. This study investigated lifecourse predictors of sex hormones in men in the Newcastle Thousand Families birth cohort. Methods: The Newcastle Thousand Families Study is a prospective study initiated in 1947. At age 49‐51 years, 574 study members returned detailed self‐completion question…
P2-239 Associations between sex hormones and bone mineral density and bone resorption in 50-year-old men
Introduction While much research relating sex hormones to bone health has centred on oestrogen deficiency in postmenopausal women, far less is known regarding the potential for sex hormone levels to influence bone health in men. We investigated the influence of sex hormone concentrations on bone health in men at age 50, using data from the Newcastle Thousand Families Study. Methods The study included 171 men who attended for DEXA scanning (giving…
Folic acid supplementation and social deprivation
Objective To assess the use of folic acid supplementation in relation to small-area measures of social deprivation. Design Cohort study. Setting Antenatal clinic, Women's Outpatients Services, Cumberland Infirmary, Carlisle, UK. Subjects Four hundred and fifty women attending their 18-week antenatal clinic appointment. No selection criteria were applied. Townsend scores were allocated using postcodes to provide a small-area measure (enumeration d…
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Folic acid supplementation and social deprivation
Objective To assess the use of folic acid supplementation in relation to small-area measures of social deprivation. Design Cohort study. Setting Antenatal clinic, Women's Outpatients Services, Cumberland Infirmary, Carlisle, UK. Subjects Four hundred and fifty women attending their 18-week antenatal clinic appointment. No selection criteria were applied. Townsend scores were allocated using postcodes to provide a small-area measure (enumeration d…
Birth weight and early socio‐economic disadvantage as predictors of sex hormones and sex hormone binding globulin in men at age 49–51 years
Objectives: A number of associations have been shown between early growth and later sex hormone levels in women, but less is known about this relationship in men. This study investigated lifecourse predictors of sex hormones in men in the Newcastle Thousand Families birth cohort. Methods: The Newcastle Thousand Families Study is a prospective study initiated in 1947. At age 49‐51 years, 574 study members returned detailed self‐completion question…
P2-239 Associations between sex hormones and bone mineral density and bone resorption in 50-year-old men
Introduction While much research relating sex hormones to bone health has centred on oestrogen deficiency in postmenopausal women, far less is known regarding the potential for sex hormone levels to influence bone health in men. We investigated the influence of sex hormone concentrations on bone health in men at age 50, using data from the Newcastle Thousand Families Study. Methods The study included 171 men who attended for DEXA scanning (giving…
Assessment of Offspring DNA Methylation across the Lifecourse Associated with Prenatal Maternal Smoking Using Bayesian Mixture Modelling
A growing body of research has implicated DNA methylation as a potential mediator of the effects of maternal smoking in pregnancy on offspring ill-health. Data were available from a UK birth cohort of children with DNA methylation measured at birth, age 7 and 17. One issue when analysing genome-wide DNA methylation data is the correlation of methylation levels between CpG sites, though this can be crudely bypassed using a data reduction method. I…
Serum cholesterol, MTHFR methylation, and symptoms of depression in children
Depression is associated with dietary factors and epigenetics. Serum cholesterol, which is prone to dietary influences, has been linked to symptoms of depression. This relationship may be (in part) due to altered epigenetic regulation of Methylenetetrahydrofolate Reductase (MTHFR). MTHFR codes for the MTHFR enzyme, which has diverse metabolic functions, and has recently been linked individually with diet, serum cholesterol levels and depressive s…
Medicine (5 works) · Internal Medicine (4 works) · Biology (3 works) · Endocrinology (3 works) · Pregnancy (3 works) · Androgen (2 works) · Birth, Development, and Health (2 works) · Body mass index (2 works) · DNA methylation (2 works) · Endocrinology (2 works)