Alla G Reddy
Biographic Data
| ID | 4411720 |
|---|---|
| NAME | Alla G Reddy |
| GIVEN NAMES | Alla G |
| FAMILY NAME | Reddy |
| SIGNATURE | REDDY A G |
| AFFILIATIONS | Centre for Cellular and Molecular Biology |
| VERIFIED | No |
| TOTAL WORKS | 6 |
| TOTAL CITATIONS | 6 |
| AUTHOR COUNT | 6 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2005 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Prevalence of Low EPHX1 Activity‐Associated Genotypes in Himalayan Populations of India
Objectives The EPHX1 gene encodes human microsomal epoxide hydrolase 1, which helps in biotransformation processes. Its activity is influenced by combinations of genotypes at its polymorphic sites. There are no data on the EPHX1 gene variants in the Indian Himalayan and adjoining populations (HAAPs). Therefore, this study aims to investigate the activity‐associated genotypes of the EPHX1 gene variants in the HAAPs. Materials and Methods The EPHX1…
Mitochondrial DNA variation and substructure among the tribal populations of Andhra Pradesh, India
We analyzed mtDNA HVR-I variation among six tribal populations-Andh, Pardan, Gond, Naikpod, Kolam and Chenchu--from Andhra Pradesh. These tribes belong to the Dravidian and Indo-European linguistic group. Except for Chenchu, the rest of the tribal samples were collected from two or more than two locations. The analysis of molecular variance (AMOVA) of the sequences yields a significant F(ST) value (0.045), suggesting a fair degree of genetic diff…
Single nucleotide polymorphisms in alcohol dehydrogenase genes among some Indian populations
Seven ADH genes, identified until now, located in the long arm of human chromosome 4, produce seven different isozymes involved in the metabolism of ethanol to acetaldehyde. Of the more than 500 SNPs reported in the coding and non‐coding regions of these genes in the world databases, 11 are more extensively studied. Three SNPs, ADH1B Arg47His (Exon3), ADH1B Arg369Cys (Exon9) and ADH1C Val349Ile (Exon8), are functionally validated in terms of phen…
Asian and non‐Asian origins of Mon‐Khmer‐ and Mundari‐speaking Austro‐Asiatic populations of India
In the present study, we analyzed 1,686 samples from 31 tribal populations of India for the mitochondrial DNA 9‐base‐pair deletion/insertion polymorphism, and characterized them based on the relevant mitochondrial DNA coding‐region single nucleotide polymorphisms and hypervariable region I motifs, to test the genetic origins of the ethnically and linguistically heterogeneous Austro‐Asiatic tribes of India. A comparative analysis of our results wi…
Reconstructing the Origin of Andaman Islanders
The origin of the Andaman "Negrito" and Nicobar "Mongoloid" populations has been ambiguous. Our analyses of complete mitochondrial DNA sequences from Onges and Great Andaman populations revealed two deeply branching clades that share their most recent common ancestor in founder haplogroup M, with lineages spread among India, Africa, East Asia, New Guinea, and Australia. This distribution suggests that these two clades have likely survived in gene…
Microsatellite Diversity in Andhra Pradesh, India: Genetic Stratification Versus Social Stratification
DNA samples of 948 individuals belonging to 27 populations from southern Andhra Pradesh were analyzed for nine AmpFlSTR Profiler Plus loci. The nature and extent of genomic diversity within and between these populations have been examined with reference to socioeconomic and geographic affiliations. The results suggest that the average heterozygosity is uniformly high in these populations (>0.80) and that the patterns of allele distributions are s…
Microsatellite Diversity in Andhra Pradesh, India: Genetic Stratification Versus Social Stratification
DNA samples of 948 individuals belonging to 27 populations from southern Andhra Pradesh were analyzed for nine AmpFlSTR Profiler Plus loci. The nature and extent of genomic diversity within and between these populations have been examined with reference to socioeconomic and geographic affiliations. The results suggest that the average heterozygosity is uniformly high in these populations (>0.80) and that the patterns of allele distributions are s…
Reconstructing the Origin of Andaman Islanders
The origin of the Andaman "Negrito" and Nicobar "Mongoloid" populations has been ambiguous. Our analyses of complete mitochondrial DNA sequences from Onges and Great Andaman populations revealed two deeply branching clades that share their most recent common ancestor in founder haplogroup M, with lineages spread among India, Africa, East Asia, New Guinea, and Australia. This distribution suggests that these two clades have likely survived in gene…
Microsatellite Diversity in Andhra Pradesh, India: Genetic Stratification Versus Social Stratification
DNA samples of 948 individuals belonging to 27 populations from southern Andhra Pradesh were analyzed for nine AmpFlSTR Profiler Plus loci. The nature and extent of genomic diversity within and between these populations have been examined with reference to socioeconomic and geographic affiliations. The results suggest that the average heterozygosity is uniformly high in these populations (>0.80) and that the patterns of allele distributions are s…
Asian and non‐Asian origins of Mon‐Khmer‐ and Mundari‐speaking Austro‐Asiatic populations of India
In the present study, we analyzed 1,686 samples from 31 tribal populations of India for the mitochondrial DNA 9‐base‐pair deletion/insertion polymorphism, and characterized them based on the relevant mitochondrial DNA coding‐region single nucleotide polymorphisms and hypervariable region I motifs, to test the genetic origins of the ethnically and linguistically heterogeneous Austro‐Asiatic tribes of India. A comparative analysis of our results wi…
Single nucleotide polymorphisms in alcohol dehydrogenase genes among some Indian populations
Seven ADH genes, identified until now, located in the long arm of human chromosome 4, produce seven different isozymes involved in the metabolism of ethanol to acetaldehyde. Of the more than 500 SNPs reported in the coding and non‐coding regions of these genes in the world databases, 11 are more extensively studied. Three SNPs, ADH1B Arg47His (Exon3), ADH1B Arg369Cys (Exon9) and ADH1C Val349Ile (Exon8), are functionally validated in terms of phen…
Mitochondrial DNA variation and substructure among the tribal populations of Andhra Pradesh, India
We analyzed mtDNA HVR-I variation among six tribal populations-Andh, Pardan, Gond, Naikpod, Kolam and Chenchu--from Andhra Pradesh. These tribes belong to the Dravidian and Indo-European linguistic group. Except for Chenchu, the rest of the tribal samples were collected from two or more than two locations. The analysis of molecular variance (AMOVA) of the sequences yields a significant F(ST) value (0.045), suggesting a fair degree of genetic diff…
Prevalence of Low EPHX1 Activity‐Associated Genotypes in Himalayan Populations of India
Objectives The EPHX1 gene encodes human microsomal epoxide hydrolase 1, which helps in biotransformation processes. Its activity is influenced by combinations of genotypes at its polymorphic sites. There are no data on the EPHX1 gene variants in the Indian Himalayan and adjoining populations (HAAPs). Therefore, this study aims to investigate the activity‐associated genotypes of the EPHX1 gene variants in the HAAPs. Materials and Methods The EPHX1…
Biology (5 works) · Demography (4 works) · Forensic and Genetic Research (4 works) · Gene (4 works) · Genetics (4 works) · Genotype (4 works) · Geography (4 works) · Population (3 works) · Sociology (3 works) · Allele (2 works)