Sebastian Porsdam Mann
Biographic Data
| ID | 4466030 |
|---|---|
| NAME | Sebastian Porsdam Mann |
| GIVEN NAMES | Sebastian Porsdam |
| FAMILY NAME | Mann |
| SIGNATURE | MANN S P |
| AFFILIATIONS | University of Copenhagen |
| ORCID | 0000-0002-1867-2097 |
| VERIFIED | Yes |
| TOTAL WORKS | 24 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 23 |
| EDITOR COUNT | 1 |
| FIRST PUBLICATION YEAR | 2018 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Against mandatory prompt disclosure in AI-assisted scholarship
Large language models (LLMs) are becoming routine as tools for drafting, editing, and revising scholarly manuscripts, raising difficult questions about how much transparency is needed to assess research integrity, authorship claims, and accountability. In response, some authors have proposed that researchers who use LLMs in manuscript preparation should be required to submit the prompts they used, together with the generated outputs, as supplemen…
Leaving no one behind
If geroscience research delivers on its promise to increase healthy life years, societies around the globe will face profound moral questions. Unlike research addressing diseases such as cardiovascular disease, cancer, or diabetes, biological targeting of the process of senescence has a far wider, almost unprecedented sweep, potentially benefiting all people across the lifespan and future generations. This paper proposes that geroscience products…
When to create embryos or organoids for research
The development of brain organoids and use of human embryonic neural structures for research each raise distinct ethical considerations that require careful analysis. We propose that rather than attempting to resolve longstanding debates about embryonic moral status, a more productive approach is to examine how different positions on this fundamental question lead to distinct conclusions about appropriate research strategies. For those who ground…
Normalising transparency
i We adopt the definition used by Nature portfolio journals: 'AI-assisted improvements to human-generated texts for readability and style, and to ensure that the texts are free of errors in grammar, spelling, punctuation and tone.These AI-assisted improvements may include wording and formatting changes to the texts, but do not include generative editorial work and autonomous content creation'. 18 As Hosseini and colleagues 16 note, using the shor…
Chat-IRB for LMICs
Compared with high-income countries (HICs), developing ‘Chat-IRB’—application-specific large language models for research ethics review—may have different implications for resource-constrained Research Ethics Committees or Institutional Review Boards (IRBs) in low- and middle-income countries (LMICs). While certain concerns raised by Moodley, Malpani, and Reis—including resource challenges, reviewing research conducted in LMICs, and automation bi…
Digital Doppelgängers, Human Relationships, and Practical Identity
In this paper, we examine the potential effects of relationships with Large Language Model (LLM)‐based digital doppelgängers (DDs) on users' values, concerns, and interests, that is, on their practical identity. DDs are artificially intelligent conversational agents trained on individuals' data to replicate their speech patterns, mannerisms, and personality traits. We start by showing that practical identity is largely defined by the relationship…
On Whether Sex Is Binary
The calculator analogy
Like the arrival of calculators in 1970s classrooms, large language models (LLMs) provoke both fears of intellectual deskilling and hopes of more efficient learning. In this paper we analyze the calculator analogy, arguing that while it is a useful starting point to understand the potential impact of LLMs in education, it is ultimately insufficient. We show where the analogy holds and, just as importantly, where its limitations reveal the unique …
Augmenting research consent
The integration of artificial intelligence (AI), particularly large language models (LLMs) like OpenAI’s ChatGPT, into clinical research could significantly enhance the informed consent process. This paper critically examines the ethical implications of employing LLMs to facilitate consent in clinical research. LLMs could offer considerable benefits, such as improving participant understanding and engagement, broadening participants’ access to th…
Psychedelics beyond medicine
The current revival of interest in classic psychedelics and other psychoactives such as ketamine and MDMA, coupled with changes to their regulatory status in many jurisdictions, necessitates rigorous ethical guidelines both within and beyond clinical and scientific contexts. This paper examines crucial ethical, philosophical, and policy considerations needed to ensure psychedelic use across various settings remains equitable, beneficial, consensu…
Respecting formerly autonomous persons
Digital twins or AI SIMs? What to call generative AI systems designed to emulate specific individuals, in healthcare settings and beyond
Chat-IRB? How application-specific language models can enhance research ethics review
Institutional review boards (IRBs) play a crucial role in ensuring the ethical conduct of human subjects research, but face challenges including inconsistency, delays, and inefficiencies. We propose the development and implementation of application-specific large language models (LLMs) to facilitate IRB review processes. These IRB-specific LLMs would be fine-tuned on IRB-specific literature and institutional datasets, and equipped with retrieval …
On Religious Influence in Bioethics
The World Congress of Bioethics held in Qatar in 2024 (WCB 2024) sparked controversy around the role of religion in bioethics, highlighting the need for critical discussions. During the congress, there was a strong push for incorporating religious values into bioethical discourse, raising questions about the validity and implications of such an approach. This paper examines the influence of religious thought on bioethical discussions, and the ong…
Personalizing AI art boosts credit, not beauty
Generative AI and medical ethics
Digital Duplicates, Relational Scarcity, and Value
Danaher and Nyholm (2024a) have recently proposed that digital duplicates—such as fine-tuned, “personalized” large language models that closely mimic a particular individual—might reduce that individual’s scarcity and thus increase the amount of instrumental value they can bring to the world. In this commentary, we introduce the notion of relational scarcity and explore how digital duplicates would affect the value of interpersonal relationships
The right to science or to Wissenschaft ? Five lessons from the travaux préparatoires
This article identifies novel insights from a detailed analysis of the travaux préparatoires of the right to science provisions in the Universal Declaration of Human Rights (UDHR) and the International Covenant on Economic, Social and Cultural Rights (ICESCR). It makes five main contributions. First, it demonstrates the bidirectional influence between the UDHR and the earlier American Declaration of the Rights and Duties of Man in the formulation…
Anticipation and diplomacy (with)in science
How can scientists assist society and contribute to international policymaking – and just as crucially, how can society engage with and shape science? What will it take to make modern science diplomacy for the Anthropocene successful so that the benefits of science are furthered and its risks and harms, as far as possible, prevented? In this article, we explore the relevance and usefulness of three areas of study to these questions: science diplo…
Innovating in uncharted terrain
Science permeates almost every aspect of society, yet the human right to science remains neglected. In 2020, the Committee on Economic, Social and Cultural Rights published its General Comment No. 25, intended to interpret the abstract provisions of Article 15 ICESCR. As a non-binding treaty body pronouncement, the General Comment’s reception and impact depend on its normative legitimacy – the extent to which its reasoning is coherent, determinat…
The Right to Science
That everyone has a human right to enjoy the benefits of the progress of science and its applications comes as a surprise to many. Nevertheless, this right is pertinent to numerous issues at the intersection of science and society: open access; 'dual use' science; access to ownership and dissemination of data, knowledge, methods and the affordances and applications thereof; as well as the role of international co-operation, human dignity and othe…
Blockchain, consent and prosent for medical research
Recent advances in medical and information technologies, the availability of new types of medical data, the requirement of increasing numbers of study participants, as well as difficulties in recruitment and retention, all present serious problems for traditional models of specific and informed consent to medical research. However, these advances also enable novel ways to securely share and analyse data. This paper introduces one of these advance…
Right to Science
Is the use of modafinil, a pharmacological cognitive enhancer, cheating
Drugs used to provide improvement of cognitive functioning have been shown to be effective in healthy individuals. It is sometimes assumed that the use of these drugs constitutes cheating in an academic context. We examine whether this assumption is ethically sound. Beyond providing the most up-to-date discussion of modafinil use in an academic context, this contribution includes an overview of the safety of modafinil use in greater depth than pr…
No prominent works on this page.
Is the use of modafinil, a pharmacological cognitive enhancer, cheating
Drugs used to provide improvement of cognitive functioning have been shown to be effective in healthy individuals. It is sometimes assumed that the use of these drugs constitutes cheating in an academic context. We examine whether this assumption is ethically sound. Beyond providing the most up-to-date discussion of modafinil use in an academic context, this contribution includes an overview of the safety of modafinil use in greater depth than pr…
The Right to Science
That everyone has a human right to enjoy the benefits of the progress of science and its applications comes as a surprise to many. Nevertheless, this right is pertinent to numerous issues at the intersection of science and society: open access; 'dual use' science; access to ownership and dissemination of data, knowledge, methods and the affordances and applications thereof; as well as the role of international co-operation, human dignity and othe…
Blockchain, consent and prosent for medical research
Recent advances in medical and information technologies, the availability of new types of medical data, the requirement of increasing numbers of study participants, as well as difficulties in recruitment and retention, all present serious problems for traditional models of specific and informed consent to medical research. However, these advances also enable novel ways to securely share and analyse data. This paper introduces one of these advance…
Right to Science
Anticipation and diplomacy (with)in science
How can scientists assist society and contribute to international policymaking – and just as crucially, how can society engage with and shape science? What will it take to make modern science diplomacy for the Anthropocene successful so that the benefits of science are furthered and its risks and harms, as far as possible, prevented? In this article, we explore the relevance and usefulness of three areas of study to these questions: science diplo…
Innovating in uncharted terrain
Science permeates almost every aspect of society, yet the human right to science remains neglected. In 2020, the Committee on Economic, Social and Cultural Rights published its General Comment No. 25, intended to interpret the abstract provisions of Article 15 ICESCR. As a non-binding treaty body pronouncement, the General Comment’s reception and impact depend on its normative legitimacy – the extent to which its reasoning is coherent, determinat…
Generative AI and medical ethics
Digital Duplicates, Relational Scarcity, and Value
Danaher and Nyholm (2024a) have recently proposed that digital duplicates—such as fine-tuned, “personalized” large language models that closely mimic a particular individual—might reduce that individual’s scarcity and thus increase the amount of instrumental value they can bring to the world. In this commentary, we introduce the notion of relational scarcity and explore how digital duplicates would affect the value of interpersonal relationships
The right to science or to Wissenschaft ? Five lessons from the travaux préparatoires
This article identifies novel insights from a detailed analysis of the travaux préparatoires of the right to science provisions in the Universal Declaration of Human Rights (UDHR) and the International Covenant on Economic, Social and Cultural Rights (ICESCR). It makes five main contributions. First, it demonstrates the bidirectional influence between the UDHR and the earlier American Declaration of the Rights and Duties of Man in the formulation…
Augmenting research consent
The integration of artificial intelligence (AI), particularly large language models (LLMs) like OpenAI’s ChatGPT, into clinical research could significantly enhance the informed consent process. This paper critically examines the ethical implications of employing LLMs to facilitate consent in clinical research. LLMs could offer considerable benefits, such as improving participant understanding and engagement, broadening participants’ access to th…
Psychedelics beyond medicine
The current revival of interest in classic psychedelics and other psychoactives such as ketamine and MDMA, coupled with changes to their regulatory status in many jurisdictions, necessitates rigorous ethical guidelines both within and beyond clinical and scientific contexts. This paper examines crucial ethical, philosophical, and policy considerations needed to ensure psychedelic use across various settings remains equitable, beneficial, consensu…
Respecting formerly autonomous persons
Digital twins or AI SIMs? What to call generative AI systems designed to emulate specific individuals, in healthcare settings and beyond
Chat-IRB? How application-specific language models can enhance research ethics review
Institutional review boards (IRBs) play a crucial role in ensuring the ethical conduct of human subjects research, but face challenges including inconsistency, delays, and inefficiencies. We propose the development and implementation of application-specific large language models (LLMs) to facilitate IRB review processes. These IRB-specific LLMs would be fine-tuned on IRB-specific literature and institutional datasets, and equipped with retrieval …
On Religious Influence in Bioethics
The World Congress of Bioethics held in Qatar in 2024 (WCB 2024) sparked controversy around the role of religion in bioethics, highlighting the need for critical discussions. During the congress, there was a strong push for incorporating religious values into bioethical discourse, raising questions about the validity and implications of such an approach. This paper examines the influence of religious thought on bioethical discussions, and the ong…
Personalizing AI art boosts credit, not beauty
Against mandatory prompt disclosure in AI-assisted scholarship
Large language models (LLMs) are becoming routine as tools for drafting, editing, and revising scholarly manuscripts, raising difficult questions about how much transparency is needed to assess research integrity, authorship claims, and accountability. In response, some authors have proposed that researchers who use LLMs in manuscript preparation should be required to submit the prompts they used, together with the generated outputs, as supplemen…
Leaving no one behind
If geroscience research delivers on its promise to increase healthy life years, societies around the globe will face profound moral questions. Unlike research addressing diseases such as cardiovascular disease, cancer, or diabetes, biological targeting of the process of senescence has a far wider, almost unprecedented sweep, potentially benefiting all people across the lifespan and future generations. This paper proposes that geroscience products…
When to create embryos or organoids for research
The development of brain organoids and use of human embryonic neural structures for research each raise distinct ethical considerations that require careful analysis. We propose that rather than attempting to resolve longstanding debates about embryonic moral status, a more productive approach is to examine how different positions on this fundamental question lead to distinct conclusions about appropriate research strategies. For those who ground…
Normalising transparency
i We adopt the definition used by Nature portfolio journals: 'AI-assisted improvements to human-generated texts for readability and style, and to ensure that the texts are free of errors in grammar, spelling, punctuation and tone.These AI-assisted improvements may include wording and formatting changes to the texts, but do not include generative editorial work and autonomous content creation'. 18 As Hosseini and colleagues 16 note, using the shor…
Chat-IRB for LMICs
Compared with high-income countries (HICs), developing ‘Chat-IRB’—application-specific large language models for research ethics review—may have different implications for resource-constrained Research Ethics Committees or Institutional Review Boards (IRBs) in low- and middle-income countries (LMICs). While certain concerns raised by Moodley, Malpani, and Reis—including resource challenges, reviewing research conducted in LMICs, and automation bi…
Digital Doppelgängers, Human Relationships, and Practical Identity
In this paper, we examine the potential effects of relationships with Large Language Model (LLM)‐based digital doppelgängers (DDs) on users' values, concerns, and interests, that is, on their practical identity. DDs are artificially intelligent conversational agents trained on individuals' data to replicate their speech patterns, mannerisms, and personality traits. We start by showing that practical identity is largely defined by the relationship…
On Whether Sex Is Binary
The calculator analogy
Like the arrival of calculators in 1970s classrooms, large language models (LLMs) provoke both fears of intellectual deskilling and hopes of more efficient learning. In this paper we analyze the calculator analogy, arguing that while it is a useful starting point to understand the potential impact of LLMs in education, it is ultimately insufficient. We show where the analogy holds and, just as importantly, where its limitations reveal the unique …
Political science (10 works) · Computer Science (9 works) · Law (8 works) · Psychology (6 works) · Artificial Intelligence in Healthcare and Education (5 works) · Philosophy (5 works) · Sociology (5 works) · Data science (4 works) · Engineering ethics (4 works) · Epistemology (4 works)