Kathleen A O'Connor
Biographic Data
| ID | 4576554 |
|---|---|
| NAME | Kathleen A O'Connor |
| GIVEN NAMES | Kathleen A |
| FAMILY NAME | O'Connor |
| SIGNATURE | CONNOR K A O |
| AFFILIATIONS | Department of Anthropology University of Washington Seattle Washington 98195 |
| VERIFIED | No |
| TOTAL WORKS | 12 |
| TOTAL CITATIONS | 24 |
| AUTHOR COUNT | 12 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1999 |
| LATEST PUBLICATION YEAR | 2016 |
| H-INDEX | 4 |
Salivary but not blood cortisol excretion is associated with metabolic biomarkers in healthy young women
OBJECTIVES: Elevated and suppressed concentrations of cortisol have been linked with less favorable metabolic biomarkers, such as elevated lipids and glycosylated hemoglobin (HbA1c). Based on recent work reporting that some individuals secrete more cortisol into saliva (high saliva-to-blood cortisol ratio; high secretors) than others after correcting for blood cortisol concentrations, our objectives were to examine (1) whether lipids and glycosyl…
Sensitivity and specificity of C‐reactive protein and α 1 ‐acid glycoprotein for episodes of acute infection among children in kilimanjaro, tanzania
OBJECTIVES: Biomarkers of inflammation, including C-reactive protein (CRP) and α(1) -acid glycoprotein (AGP), have tremendous potential in anthropological, public health, and nutrition research as objective indicators of acute infection; however, their usage is limited by the lack of widely agreed upon, reliable cutpoints to define infection. We assessed the sensitivity and specificity of CRP and AGP for identifying acute infectious disease (ID) …
Salivary concentration of progesterone and cortisol significantly differs across individuals after correcting for blood hormone values
Between‐individual variation of salivary progesterone (P4) and cortisol levels does not always closely reflect blood hormone concentrations. This may be partly a function of individual differences in salivary hormone excretion. We tested whether time of day at sampling and ethnicity contributed to individual variation in salivary hormones after adjusting for blood hormone levels. Forty‐three Caucasian and 15 Japanese women (18–34 years) collected…
The effects of a long‐term psychosocial stress on reproductive indicators in the baboon
Psychosocial stress is thought to negatively impact fecundity, but human studies are confounded by variation in nutrition and lifestyle. Baboons offer a useful model to test the effect of prolonged mild stress on reproductive indicators in a controlled setting. Following relocation from social groups to solitary housing, a previously documented stressful event for nonhuman primates, daily urine samples, tumescence, and menstrual bleeding were mon…
Responsiveness of the reproductive axis to a single missed evening meal in young adult males
Objectives: The male reproductive axis is responsive to energetic deficits, including multiday fasts, but little is known about brief periods of fasting ( Methods: Participants provided daily saliva and urine samples for two baseline days and the morning following an evening fast (water only after 4 PM). Testosterone, cortisol, and luteinizing hormone were measured with enzyme immunoassays. Results: Fasting specimens had significantly lower overn…
C‐reactive protein across the menstrual cycle
C‐reactive protein (CRP) is a widely used, sensitive biomarker of inflammation. Studies conducted among users of exogenous hormones suggest that estrogen increases CRP, whereas progesterone decreases CRP. Examinations of CRP in normally cycling women suggest the opposite: CRP is negatively associated with endogenous estrogen and positively associated with endogenous progesterone. This work evaluates the association between menstrual cycle‐related…
Distribution of postpartum amenorrhea in rural Bangladeshi women
Previous studies of postpartum amenorrhea (PPA) demonstrated distinct subgroups of women with short and long durations of amenorrhea. This phenomenon was attributed to cases where breastfeeding is absent because of pregnancy loss or infant death, or confusion of postpartum bleeding with resumption of menses. We explored these ideas using data from an 11‐month prospective study in Bangladesh in which 858 women provided twice‐weekly interviews and …
Mortality models for paleodemography
Introduction Population scientists concerned with long-term trends in human mortality ought to be interested in skeletal samples from extinct communities. Such samples are, in principle, the only possible source of information for most pre-industrial populations lacking written records – by far the most common kind of human community that has ever existed. Samples of skeletons provide two broad classes of information of potential interest to demo…
Menstrual cycle variability and the perimenopause
Menopause, the final cessation of menstrual cycling, occurs when the pool of ovarian follicles is depleted. The one to five years just prior to the menopause are usually marked by increasing variability in menstrual cycle length, frequency of ovulation, and levels of reproductive hormones. Little is known about the mechanisms that account for these characteristics of ovarian cycles as the menopause approaches. Some evidence suggests that the dwin…
Hormones, Health, and Behavior
Edited by C. Panter-Brick and C.M. Worthman. Cambridge University Press. 1999. 290 pp. ISBN 0 521 57332 7. $69.95 (hardcover).
Pregnancy sickness
Pregnancy sickness
C‐reactive protein across the menstrual cycle
C‐reactive protein (CRP) is a widely used, sensitive biomarker of inflammation. Studies conducted among users of exogenous hormones suggest that estrogen increases CRP, whereas progesterone decreases CRP. Examinations of CRP in normally cycling women suggest the opposite: CRP is negatively associated with endogenous estrogen and positively associated with endogenous progesterone. This work evaluates the association between menstrual cycle‐related…
Salivary concentration of progesterone and cortisol significantly differs across individuals after correcting for blood hormone values
Between‐individual variation of salivary progesterone (P4) and cortisol levels does not always closely reflect blood hormone concentrations. This may be partly a function of individual differences in salivary hormone excretion. We tested whether time of day at sampling and ethnicity contributed to individual variation in salivary hormones after adjusting for blood hormone levels. Forty‐three Caucasian and 15 Japanese women (18–34 years) collected…
Distribution of postpartum amenorrhea in rural Bangladeshi women
Previous studies of postpartum amenorrhea (PPA) demonstrated distinct subgroups of women with short and long durations of amenorrhea. This phenomenon was attributed to cases where breastfeeding is absent because of pregnancy loss or infant death, or confusion of postpartum bleeding with resumption of menses. We explored these ideas using data from an 11‐month prospective study in Bangladesh in which 858 women provided twice‐weekly interviews and …
The effects of a long‐term psychosocial stress on reproductive indicators in the baboon
Psychosocial stress is thought to negatively impact fecundity, but human studies are confounded by variation in nutrition and lifestyle. Baboons offer a useful model to test the effect of prolonged mild stress on reproductive indicators in a controlled setting. Following relocation from social groups to solitary housing, a previously documented stressful event for nonhuman primates, daily urine samples, tumescence, and menstrual bleeding were mon…
Pregnancy sickness
Pregnancy sickness
Hormones, Health, and Behavior
Edited by C. Panter-Brick and C.M. Worthman. Cambridge University Press. 1999. 290 pp. ISBN 0 521 57332 7. $69.95 (hardcover).
Menstrual cycle variability and the perimenopause
Menopause, the final cessation of menstrual cycling, occurs when the pool of ovarian follicles is depleted. The one to five years just prior to the menopause are usually marked by increasing variability in menstrual cycle length, frequency of ovulation, and levels of reproductive hormones. Little is known about the mechanisms that account for these characteristics of ovarian cycles as the menopause approaches. Some evidence suggests that the dwin…
Mortality models for paleodemography
Introduction Population scientists concerned with long-term trends in human mortality ought to be interested in skeletal samples from extinct communities. Such samples are, in principle, the only possible source of information for most pre-industrial populations lacking written records – by far the most common kind of human community that has ever existed. Samples of skeletons provide two broad classes of information of potential interest to demo…
Distribution of postpartum amenorrhea in rural Bangladeshi women
Previous studies of postpartum amenorrhea (PPA) demonstrated distinct subgroups of women with short and long durations of amenorrhea. This phenomenon was attributed to cases where breastfeeding is absent because of pregnancy loss or infant death, or confusion of postpartum bleeding with resumption of menses. We explored these ideas using data from an 11‐month prospective study in Bangladesh in which 858 women provided twice‐weekly interviews and …
C‐reactive protein across the menstrual cycle
C‐reactive protein (CRP) is a widely used, sensitive biomarker of inflammation. Studies conducted among users of exogenous hormones suggest that estrogen increases CRP, whereas progesterone decreases CRP. Examinations of CRP in normally cycling women suggest the opposite: CRP is negatively associated with endogenous estrogen and positively associated with endogenous progesterone. This work evaluates the association between menstrual cycle‐related…
Responsiveness of the reproductive axis to a single missed evening meal in young adult males
Objectives: The male reproductive axis is responsive to energetic deficits, including multiday fasts, but little is known about brief periods of fasting ( Methods: Participants provided daily saliva and urine samples for two baseline days and the morning following an evening fast (water only after 4 PM). Testosterone, cortisol, and luteinizing hormone were measured with enzyme immunoassays. Results: Fasting specimens had significantly lower overn…
The effects of a long‐term psychosocial stress on reproductive indicators in the baboon
Psychosocial stress is thought to negatively impact fecundity, but human studies are confounded by variation in nutrition and lifestyle. Baboons offer a useful model to test the effect of prolonged mild stress on reproductive indicators in a controlled setting. Following relocation from social groups to solitary housing, a previously documented stressful event for nonhuman primates, daily urine samples, tumescence, and menstrual bleeding were mon…
Sensitivity and specificity of C‐reactive protein and α 1 ‐acid glycoprotein for episodes of acute infection among children in kilimanjaro, tanzania
OBJECTIVES: Biomarkers of inflammation, including C-reactive protein (CRP) and α(1) -acid glycoprotein (AGP), have tremendous potential in anthropological, public health, and nutrition research as objective indicators of acute infection; however, their usage is limited by the lack of widely agreed upon, reliable cutpoints to define infection. We assessed the sensitivity and specificity of CRP and AGP for identifying acute infectious disease (ID) …
Salivary concentration of progesterone and cortisol significantly differs across individuals after correcting for blood hormone values
Between‐individual variation of salivary progesterone (P4) and cortisol levels does not always closely reflect blood hormone concentrations. This may be partly a function of individual differences in salivary hormone excretion. We tested whether time of day at sampling and ethnicity contributed to individual variation in salivary hormones after adjusting for blood hormone levels. Forty‐three Caucasian and 15 Japanese women (18–34 years) collected…
Salivary but not blood cortisol excretion is associated with metabolic biomarkers in healthy young women
OBJECTIVES: Elevated and suppressed concentrations of cortisol have been linked with less favorable metabolic biomarkers, such as elevated lipids and glycosylated hemoglobin (HbA1c). Based on recent work reporting that some individuals secrete more cortisol into saliva (high saliva-to-blood cortisol ratio; high secretors) than others after correcting for blood cortisol concentrations, our objectives were to examine (1) whether lipids and glycosyl…
Medicine (9 works) · Internal Medicine (8 works) · Endocrinology (5 works) · Physiology (5 works) · Demography (4 works) · Hormone (4 works) · Internal Medicine (4 works) · Population (4 works) · Biology (3 works) · Endocrinology (3 works)