Concepción De La Rúa Vaca
Biographic Data
| ID | 4777927 |
|---|---|
| NAME | Concepción De La Rúa Vaca |
| GIVEN NAMES | Concepción De La Rúa |
| FAMILY NAME | Vaca |
| SIGNATURE | VACA C R |
| AFFILIATIONS | University of the Basque Country |
| ORCID | 0000-0003-4599-0020 |
| VERIFIED | Yes |
| TOTAL WORKS | 16 |
| TOTAL CITATIONS | 106 |
| AUTHOR COUNT | 16 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1995 |
| LATEST PUBLICATION YEAR | 2023 |
| H-INDEX | 6 |
High frequency of mitochondrial haplogroups H and H2 in medieval individuals from the Cathedral of Santa María (Basque Country). Their contribution to the study of inflammatory arthropathies
The haplogroup H has been associated with high mitochondrial energy efficiency, which may have favoured survival and reproduction under adverse environmental conditions. On the other hand, it enhances the production of Reactive Oxygen Species (ROS), which are involved in the pathogenesis of several arthropathies, especially those of inflammatory origin (IAs). In the present study, we analysed mtDNA haplogroups H and H2 in a sample composed of 55 …
The domestic dog that lived ∼17,000 years ago in the Lower Magdalenian of Erralla site (Basque Country): A radiometric and genetic analysis
Dogs are known to be the first species domesticated by humans, although the geographic and temporal origin of this process is still under debate in different fields of knowledge. In the present study, we examined a humerus from a canid recovered in the Lower Magdalenian level of the site of Erralla (Zestoa, Gipuzkoa, Basque Country, Spain), combining morphology, radiocarbon dating and genetics. Our results confirm the identification of this speci…
A recording form for differential diagnosis of arthropathies
The present study is focused on a group of arthropathies that may have very similar bone manifestations (rheumatoid arthritis, ankylosing spondylitis, reactive arthritis, psoriatic arthritis, osteoarthritis and diffuse idiopathic skeletal hyperostosis), which makes it more difficult to diagnose them in human remains from archaeological contexts. A stepwise recording form was designed in order to improve the identification and differential diagnos…
Genetic studies on the prehispanic population buried in Punta Azul cave (El Hierro, Canary Islands)
Demographic differences between funerary caves and megalithic graves of northern S panish L ate N eolithic/Early Chalcolithic
OBJECTIVES: The study focuses on the estimation of demographic parameters of Late Neolithic/Early Chalcolithic (mid 4th-early 3rd millenniums cal. BC) burial sites from the La Rioja region (Ebro valley, northern Spain) to identify demographic characteristics. MATERIALS AND METHODS: The human remains come from three caves (Las Yurdinas II, Peña Larga, and La Peña de Marañón) and three megalithic graves (Alto de la Huesera, San Martín, and Peña Gue…
Early Neolithic funerary diversity and mitochondrial variability of two Iberian sites
Direct U-series analysis of the Lezetxiki humerus reveals a Middle Pleistocene age for human remains in the Basque Country (northern Iberia)
Discovery of copy number variants by multiplex amplifiable probe hybridization (Maph) in candidate pigmentation genes
Although the functional role of these structural variants in pigmentation should be the subject of future work, the results emphasize the need to consider all classes of variation (both SNPs and CNVs) when exploring the genetics of skin pigmentation
Demographic evidence of selective burial in megalithic graves of northern Spain
Influences of the European Kingdoms of Late Antiquity on the Basque Country: An Ancient‐DNA Study
The Aldaieta cemetery (6th–7th century AD, Basque Country) provides an excellent opportunity for analysing the relationships between biology and culture. Culturally it presents material features whose origins lie in the Northern Pyrenean Frankish kingdom, while genetically it reveals greater affinity to the present‐day populations of the northern Iberian Peninsula. This raises the question of the degree of influence exerted by the large European …
Insights into the “isolation” of the Basques: MtDNA lineages from the historical site of Aldaieta (6th–7th centuries AD)
We analyzed the hypervariable region I (HVR‐I) sequence variability of the mitochondrial DNA (mtDNA) of individuals buried at Aldaieta (6th–7th centuries AD) in order to find out more about the biosocial implications of this cemetery. The results, fully authenticated by means of diverse criteria (analysis of duplicates, replication in an independent laboratory, quantification of target DNA, and sequencing and cloning of polymerase chain reaction …
Rare Haplotypes in mtDNA: Applications in the Analysis of Biosocial Aspects of Past Human Populations
We report on the use of rare mutations to tackle biosocial questions such as kinship and differential burial practices from past human populations. To do this, we have inferred nucleotide position 73 of HVS-II in individuals classified as belonging to haplogroup H from 76 human dental samples from the necropolis of Aldaieta (Basque Country, Spain, 6th-7th century) by means of PCR and restriction enzyme tests. The same analysis has been performed …
Ancient mtDNA haplogroups: A new insight into the genetic history of European populations
In the present work, DNA was extracted from 63 skeletal samples recovered at the Neolithic site of San Juan ante Portam Latinam (SJAPL) (Araba, Basque Country). These samples have proved useful as genetic material for the performance of population studies. To achieve this it was necessary to overcome the methodological problems arising when working with damaged DNA molecules. We succeeded in performing an amplification and restriction analysis of…
Structuring the Genetic Heterogeneity of the Basque Population: A View from Classical Polymorphisms
In this study we analyze 18 classical polymorphisms (ABO, Rh, MNSs, Lewis, P, Duffy, Kell, ADA, ESD, PGM1, PGD, AK1, ACP1, GLO1, HP, GC, TF, and PI) in over 2000 autochthonous individuals from 14 natural districts in three provinces of the Basque Country (Alava, Guipuzcoa, and Biscay). Heterogeneity analysis via the chi2 test and a calculation of F(ST) indicate that there is significant genetic heterogeneity between the Basque districts. The R ma…
Reconstruction of Diet with Trace Elements of Bone at the Chalcolithic Site of Pico Ramos, Basque Country, Spain
Molar crown height as a means of evaluating existing dental wear scales for estimating age at death in human skeletal remains
Molar crown height as a means of evaluating existing dental wear scales for estimating age at death in human skeletal remains
Demographic evidence of selective burial in megalithic graves of northern Spain
Genetic studies on the prehispanic population buried in Punta Azul cave (El Hierro, Canary Islands)
Insights into the “isolation” of the Basques: MtDNA lineages from the historical site of Aldaieta (6th–7th centuries AD)
We analyzed the hypervariable region I (HVR‐I) sequence variability of the mitochondrial DNA (mtDNA) of individuals buried at Aldaieta (6th–7th centuries AD) in order to find out more about the biosocial implications of this cemetery. The results, fully authenticated by means of diverse criteria (analysis of duplicates, replication in an independent laboratory, quantification of target DNA, and sequencing and cloning of polymerase chain reaction …
Demographic differences between funerary caves and megalithic graves of northern S panish L ate N eolithic/Early Chalcolithic
OBJECTIVES: The study focuses on the estimation of demographic parameters of Late Neolithic/Early Chalcolithic (mid 4th-early 3rd millenniums cal. BC) burial sites from the La Rioja region (Ebro valley, northern Spain) to identify demographic characteristics. MATERIALS AND METHODS: The human remains come from three caves (Las Yurdinas II, Peña Larga, and La Peña de Marañón) and three megalithic graves (Alto de la Huesera, San Martín, and Peña Gue…
Direct U-series analysis of the Lezetxiki humerus reveals a Middle Pleistocene age for human remains in the Basque Country (northern Iberia)
Structuring the Genetic Heterogeneity of the Basque Population: A View from Classical Polymorphisms
In this study we analyze 18 classical polymorphisms (ABO, Rh, MNSs, Lewis, P, Duffy, Kell, ADA, ESD, PGM1, PGD, AK1, ACP1, GLO1, HP, GC, TF, and PI) in over 2000 autochthonous individuals from 14 natural districts in three provinces of the Basque Country (Alava, Guipuzcoa, and Biscay). Heterogeneity analysis via the chi2 test and a calculation of F(ST) indicate that there is significant genetic heterogeneity between the Basque districts. The R ma…
Rare Haplotypes in mtDNA: Applications in the Analysis of Biosocial Aspects of Past Human Populations
We report on the use of rare mutations to tackle biosocial questions such as kinship and differential burial practices from past human populations. To do this, we have inferred nucleotide position 73 of HVS-II in individuals classified as belonging to haplogroup H from 76 human dental samples from the necropolis of Aldaieta (Basque Country, Spain, 6th-7th century) by means of PCR and restriction enzyme tests. The same analysis has been performed …
Influences of the European Kingdoms of Late Antiquity on the Basque Country: An Ancient‐DNA Study
The Aldaieta cemetery (6th–7th century AD, Basque Country) provides an excellent opportunity for analysing the relationships between biology and culture. Culturally it presents material features whose origins lie in the Northern Pyrenean Frankish kingdom, while genetically it reveals greater affinity to the present‐day populations of the northern Iberian Peninsula. This raises the question of the degree of influence exerted by the large European …
Reconstruction of Diet with Trace Elements of Bone at the Chalcolithic Site of Pico Ramos, Basque Country, Spain
Early Neolithic funerary diversity and mitochondrial variability of two Iberian sites
Molar crown height as a means of evaluating existing dental wear scales for estimating age at death in human skeletal remains
Reconstruction of Diet with Trace Elements of Bone at the Chalcolithic Site of Pico Ramos, Basque Country, Spain
Ancient mtDNA haplogroups: A new insight into the genetic history of European populations
In the present work, DNA was extracted from 63 skeletal samples recovered at the Neolithic site of San Juan ante Portam Latinam (SJAPL) (Araba, Basque Country). These samples have proved useful as genetic material for the performance of population studies. To achieve this it was necessary to overcome the methodological problems arising when working with damaged DNA molecules. We succeeded in performing an amplification and restriction analysis of…
Structuring the Genetic Heterogeneity of the Basque Population: A View from Classical Polymorphisms
In this study we analyze 18 classical polymorphisms (ABO, Rh, MNSs, Lewis, P, Duffy, Kell, ADA, ESD, PGM1, PGD, AK1, ACP1, GLO1, HP, GC, TF, and PI) in over 2000 autochthonous individuals from 14 natural districts in three provinces of the Basque Country (Alava, Guipuzcoa, and Biscay). Heterogeneity analysis via the chi2 test and a calculation of F(ST) indicate that there is significant genetic heterogeneity between the Basque districts. The R ma…
Rare Haplotypes in mtDNA: Applications in the Analysis of Biosocial Aspects of Past Human Populations
We report on the use of rare mutations to tackle biosocial questions such as kinship and differential burial practices from past human populations. To do this, we have inferred nucleotide position 73 of HVS-II in individuals classified as belonging to haplogroup H from 76 human dental samples from the necropolis of Aldaieta (Basque Country, Spain, 6th-7th century) by means of PCR and restriction enzyme tests. The same analysis has been performed …
Insights into the “isolation” of the Basques: MtDNA lineages from the historical site of Aldaieta (6th–7th centuries AD)
We analyzed the hypervariable region I (HVR‐I) sequence variability of the mitochondrial DNA (mtDNA) of individuals buried at Aldaieta (6th–7th centuries AD) in order to find out more about the biosocial implications of this cemetery. The results, fully authenticated by means of diverse criteria (analysis of duplicates, replication in an independent laboratory, quantification of target DNA, and sequencing and cloning of polymerase chain reaction …
Influences of the European Kingdoms of Late Antiquity on the Basque Country: An Ancient‐DNA Study
The Aldaieta cemetery (6th–7th century AD, Basque Country) provides an excellent opportunity for analysing the relationships between biology and culture. Culturally it presents material features whose origins lie in the Northern Pyrenean Frankish kingdom, while genetically it reveals greater affinity to the present‐day populations of the northern Iberian Peninsula. This raises the question of the degree of influence exerted by the large European …
Discovery of copy number variants by multiplex amplifiable probe hybridization (Maph) in candidate pigmentation genes
Although the functional role of these structural variants in pigmentation should be the subject of future work, the results emphasize the need to consider all classes of variation (both SNPs and CNVs) when exploring the genetics of skin pigmentation
Demographic evidence of selective burial in megalithic graves of northern Spain
Genetic studies on the prehispanic population buried in Punta Azul cave (El Hierro, Canary Islands)
Demographic differences between funerary caves and megalithic graves of northern S panish L ate N eolithic/Early Chalcolithic
OBJECTIVES: The study focuses on the estimation of demographic parameters of Late Neolithic/Early Chalcolithic (mid 4th-early 3rd millenniums cal. BC) burial sites from the La Rioja region (Ebro valley, northern Spain) to identify demographic characteristics. MATERIALS AND METHODS: The human remains come from three caves (Las Yurdinas II, Peña Larga, and La Peña de Marañón) and three megalithic graves (Alto de la Huesera, San Martín, and Peña Gue…
Early Neolithic funerary diversity and mitochondrial variability of two Iberian sites
Direct U-series analysis of the Lezetxiki humerus reveals a Middle Pleistocene age for human remains in the Basque Country (northern Iberia)
A recording form for differential diagnosis of arthropathies
The present study is focused on a group of arthropathies that may have very similar bone manifestations (rheumatoid arthritis, ankylosing spondylitis, reactive arthritis, psoriatic arthritis, osteoarthritis and diffuse idiopathic skeletal hyperostosis), which makes it more difficult to diagnose them in human remains from archaeological contexts. A stepwise recording form was designed in order to improve the identification and differential diagnos…
The domestic dog that lived ∼17,000 years ago in the Lower Magdalenian of Erralla site (Basque Country): A radiometric and genetic analysis
Dogs are known to be the first species domesticated by humans, although the geographic and temporal origin of this process is still under debate in different fields of knowledge. In the present study, we examined a humerus from a canid recovered in the Lower Magdalenian level of the site of Erralla (Zestoa, Gipuzkoa, Basque Country, Spain), combining morphology, radiocarbon dating and genetics. Our results confirm the identification of this speci…
High frequency of mitochondrial haplogroups H and H2 in medieval individuals from the Cathedral of Santa María (Basque Country). Their contribution to the study of inflammatory arthropathies
The haplogroup H has been associated with high mitochondrial energy efficiency, which may have favoured survival and reproduction under adverse environmental conditions. On the other hand, it enhances the production of Reactive Oxygen Species (ROS), which are involved in the pathogenesis of several arthropathies, especially those of inflammatory origin (IAs). In the present study, we analysed mtDNA haplogroups H and H2 in a sample composed of 55 …
Geography (13 works) · Forensic Anthropology and Bioarchaeology Studies (12 works) · Biology (11 works) · Archaeology (10 works) · Demography (9 works) · Genetics (7 works) · Population (7 works) · Demography (6 works) · Archaeology and ancient environmental studies (5 works) · Cave (5 works)