David A Goldfarb
Dados Biográficos
| ID | 4871553 |
|---|---|
| NOME | David A Goldfarb |
| PRENOMES | David A |
| SOBRENOME | Goldfarb |
| ASSINATURA | GOLDFARB D A |
| AFILIAÇÕES | University of British Columbia |
| ORCID | 0000-0003-0835-9504 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 12 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 12 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1997 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2026 |
| ÍNDICE H | 0 |
Integrated epidemiologic investigation and genomic confirmation of a Klebsiella pneumoniae neonatal sepsis outbreak in Botswana
Klebsiella pneumoniae ( Kpn ) is a major cause of infant mortality worldwide, with most transmission occurring among hospitalized neonates in low- and middle-income countries where infections caused by multidrug-resistant Kpn (MDR- Kpn ) are increasingly common. We hypothesized that integrating laboratory surveillance for neonatal colonization and infection, real-time epidemiologic investigations, and whole-genome sequencing (WGS) could identify …
Admission screening for extended-spectrum cephalosporin-resistant and carbapenem-resistant Enterobacterales colonization at a referral hospital in Botswana
Extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) and carbapenem-resistant Enterobacterales (CRE) are significant contributors to infection-related mortality in low- and middle-income countries. Colonization with ESCrE and/or CRE can precede infection and serve as a reservoir for transmission within healthcare facilities and the community.We conducted a 12-month period-prevalence study, screening patients for ESCrE and CRE upon a…
Electrolyte abnormalities and clinical outcomes in children aged one month to 13 years hospitalized with acute gastroenteritis in two large referral hospitals in Botswana
Acute gastroenteritis (AGE) is a common childhood disease, with a median of 2.5 diarrhoea episodes per child per year in both low- and middle-income countries. Morbidity and mortality from AGE result from a number of causes, including electrolyte abnormalities. This study characterized children hospitalized for AGE in Botswana with and without electrolyte abnormalities. This was a prospective observational study of children under the age of 13 ye…
A call to bridge the diagnostic gap
BOX Low- and middle-income countries (LMICs) bear the greatest burden of neonatal mortality, with sepsis being a major contributor
Canada’s approach to Sars-CoV-2 sero-surveillance
Methodological Insights, Advantages and Innovations Manuscript Title
With the growth of qualitative health research in low- and middle-income countries, local health professionals are increasingly involved in facilitating interviews with their fellow health workers. Understanding the methodological implications of such situations is required to ensure high-quality study findings and to build capacity and skills for interviewers with clinical backgrounds working with limited resources. This article reports a qualit…
Covid-19 Vaccine Intentions and Perceptions Among Public School Staff of the Greater Vancouver Metropolitan Area, British Columbia, Canada
Background The purpose of this study was to explore factors associated with COVID-19 vaccine intentions among school staff as high vaccine uptake is essential to ensure schools return to normal activities. Methods Staff (e.g., teachers, administrators, student support workers) from three urban school districts in the Greater Vancouver Area of British Columbia, Canada completed a survey between February and June 2021 ( n = 2,393) on COVID-19 vacci…
Optimising the management of childhood acute diarrhoeal disease using a rapid test-and- treat strategy and/or Lactobacillus reuteri DSM 17938
Introduction The study aim was to determine if rapid enteric diagnostics followed by the provision of targeted antibiotic therapy (‘test-and-treat’) and/or Lactobacillus reuteri DSM 17938 would improve outcomes in children hospitalised in Botswana with acute gastroenteritis. Methods This was a multicentre, randomised, factorial, controlled, trial. Children aged 2–60 months admitted for acute non-bloody diarrhoea to four hospitals in southern Bots…
Beyond early initiation
Improving breastfeeding practices is key to reducing child mortality globally. Sub-optimal exclusive breastfeeding rates may be associated with inadequate hospital-based postpartum breastfeeding support, particularly in resource-limited health settings such as Malawi. While almost all children in Malawi are breastfed, it is a concern that exclusive breastfeeding rates in Malawi are declining. The objective of this study is to understand postpartu…
Intention to receive a Covid-19 vaccine
To optimize vaccine coverage, public health should focus on key messages around vaccine safety and benefit, and leverage trusted practitioners for messaging. As certain key populations identified by NACI and ACIP for early immunization report a lower intention to vaccinate, there is a need for in-depth education and support for these communities to ensure optimal uptake
Hidden Selection Bias Deriving From Donor Organ Characteristics Does Not Affect Performance Evaluations of Kidney Transplant Centers
BACKGROUND: Transplant center performance evaluations have garnered substantial attention in recent years. Among sources of bias that may affect measured performance are underlying characteristics of donor organs. An unresolved question is whether centers accepting higher-risk donations are placed in jeopardy for lower evaluations independent of actual quality of care. OBJECTIVE: The primary aim was to assess whether unmeasured characteristics of…
The Vortex and the Labyrinth
Sem obras proeminentes nesta página.
The Vortex and the Labyrinth
Hidden Selection Bias Deriving From Donor Organ Characteristics Does Not Affect Performance Evaluations of Kidney Transplant Centers
BACKGROUND: Transplant center performance evaluations have garnered substantial attention in recent years. Among sources of bias that may affect measured performance are underlying characteristics of donor organs. An unresolved question is whether centers accepting higher-risk donations are placed in jeopardy for lower evaluations independent of actual quality of care. OBJECTIVE: The primary aim was to assess whether unmeasured characteristics of…
Intention to receive a Covid-19 vaccine
To optimize vaccine coverage, public health should focus on key messages around vaccine safety and benefit, and leverage trusted practitioners for messaging. As certain key populations identified by NACI and ACIP for early immunization report a lower intention to vaccinate, there is a need for in-depth education and support for these communities to ensure optimal uptake
Covid-19 Vaccine Intentions and Perceptions Among Public School Staff of the Greater Vancouver Metropolitan Area, British Columbia, Canada
Background The purpose of this study was to explore factors associated with COVID-19 vaccine intentions among school staff as high vaccine uptake is essential to ensure schools return to normal activities. Methods Staff (e.g., teachers, administrators, student support workers) from three urban school districts in the Greater Vancouver Area of British Columbia, Canada completed a survey between February and June 2021 ( n = 2,393) on COVID-19 vacci…
Optimising the management of childhood acute diarrhoeal disease using a rapid test-and- treat strategy and/or Lactobacillus reuteri DSM 17938
Introduction The study aim was to determine if rapid enteric diagnostics followed by the provision of targeted antibiotic therapy (‘test-and-treat’) and/or Lactobacillus reuteri DSM 17938 would improve outcomes in children hospitalised in Botswana with acute gastroenteritis. Methods This was a multicentre, randomised, factorial, controlled, trial. Children aged 2–60 months admitted for acute non-bloody diarrhoea to four hospitals in southern Bots…
Beyond early initiation
Improving breastfeeding practices is key to reducing child mortality globally. Sub-optimal exclusive breastfeeding rates may be associated with inadequate hospital-based postpartum breastfeeding support, particularly in resource-limited health settings such as Malawi. While almost all children in Malawi are breastfed, it is a concern that exclusive breastfeeding rates in Malawi are declining. The objective of this study is to understand postpartu…
Methodological Insights, Advantages and Innovations Manuscript Title
With the growth of qualitative health research in low- and middle-income countries, local health professionals are increasingly involved in facilitating interviews with their fellow health workers. Understanding the methodological implications of such situations is required to ensure high-quality study findings and to build capacity and skills for interviewers with clinical backgrounds working with limited resources. This article reports a qualit…
A call to bridge the diagnostic gap
BOX Low- and middle-income countries (LMICs) bear the greatest burden of neonatal mortality, with sepsis being a major contributor
Canada’s approach to Sars-CoV-2 sero-surveillance
Admission screening for extended-spectrum cephalosporin-resistant and carbapenem-resistant Enterobacterales colonization at a referral hospital in Botswana
Extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) and carbapenem-resistant Enterobacterales (CRE) are significant contributors to infection-related mortality in low- and middle-income countries. Colonization with ESCrE and/or CRE can precede infection and serve as a reservoir for transmission within healthcare facilities and the community.We conducted a 12-month period-prevalence study, screening patients for ESCrE and CRE upon a…
Electrolyte abnormalities and clinical outcomes in children aged one month to 13 years hospitalized with acute gastroenteritis in two large referral hospitals in Botswana
Acute gastroenteritis (AGE) is a common childhood disease, with a median of 2.5 diarrhoea episodes per child per year in both low- and middle-income countries. Morbidity and mortality from AGE result from a number of causes, including electrolyte abnormalities. This study characterized children hospitalized for AGE in Botswana with and without electrolyte abnormalities. This was a prospective observational study of children under the age of 13 ye…
Integrated epidemiologic investigation and genomic confirmation of a Klebsiella pneumoniae neonatal sepsis outbreak in Botswana
Klebsiella pneumoniae ( Kpn ) is a major cause of infant mortality worldwide, with most transmission occurring among hospitalized neonates in low- and middle-income countries where infections caused by multidrug-resistant Kpn (MDR- Kpn ) are increasingly common. We hypothesized that integrating laboratory surveillance for neonatal colonization and infection, real-time epidemiologic investigations, and whole-genome sequencing (WGS) could identify …
Medicine (9 obras) · Nursing (5 obras) · Internal Medicine (4 obras) · Pediatrics (4 obras) · Child Nutrition and Water Access (3 obras) · Family medicine (3 obras) · Health care (3 obras) · Political science (3 obras) · Psychology (3 obras) · Public health (3 obras)