Ana Fernández‐santander
Biographic Data
| ID | 4885680 |
|---|---|
| NAME | Ana Fernández‐santander |
| GIVEN NAMES | Ana |
| FAMILY NAME | Fernández‐santander |
| SIGNATURE | SANTANDER A F |
| AFFILIATIONS | Universidad Europea de Madrid |
| ORCID | 0000-0001-7545-1170 |
| VERIFIED | Yes |
| TOTAL WORKS | 11 |
| TOTAL CITATIONS | 2 |
| AUTHOR COUNT | 11 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1998 |
| LATEST PUBLICATION YEAR | 2024 |
| H-INDEX | 1 |
Worldwide distribution of genetic factors related to severity of Covid-19 infection
Considering the caveats of PRS transferability across ethnicities, our analysis showed that American populations present the highest genetic risk score, hence potentially higher propensity, for COVID-19 severity. Independent validation is warranted with additional summary statistics and phenotype data
UDP-glucuronosyltransferase genetic variation in North African populations: A comparison with African and European data
North African populations show a high frequency of carriers of UGT2B15 523Thr , a variant linked to an increased risk of prostate cancer. High Atlas Moroccans and Algerians show low frequency of UGT2B17 del , a variant associated with high concentrations of testosterone and oestradiol
A Multicentre and stratified study of the attitude of medical students towards organ donation in Spain
Spanish medical students generally have a favourable attitude towards organ donation, although 20% are not in favour
North African genetic variation of cytochrome and sulfotransferase genes
This review is focused on the genetic variation of sulfotransferases (SULTs) and cytochromes (CYPs) genes among different ethnic groups, mainly focusing in variation in North African populations. Polymorphisms of SULTs and CYPs proteins are associated with altered enzymatic activity and physical characteristics. Single nucleotide polymorphisms (SNP) in these genes have shown relevant ethnic differences among Sub-Saharan African and European group…
Genetic differences among North African Berber and Arab-speaking populations revealed by Y-STR diversity
Y-chromosome STR polymorphisms are inherited in a haploid state which makes them a powerful tool for easy tracing of paternal lineage and for use in human population evolutionary studies. North-African Y chromosomal diversity has traditionally been studied in order to find genetic and geographic associations as well as to test how natural and cultural barriers have affected the degree of genetic flow not only within North Africa but also in a wid…
STR genetic diversity in a Mediterranean population from the south of the Iberian Peninsula
Sixteen Y-chromosomal short tandem repeats (STRs) (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635 and GATA H4.1) were typed in DNA samples from 52 unrelated men and 15 autosomal STRs (CSF1PO, D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, FGA, TH01, TPOX, vWA) were also studied for a group of 90 individuals (men and women) from the sam…
Factors Influencing Prereproductive Mortality in the Isolated and Preindustrial Western Mediterranean Population of La Alpujarra, 1900–1950
We study the effects of several variables on the prereproductive mortality pattern in the isolated and rural population of La Alpujarra, located on the western Mediterranean coast (southeast Spain), in the first half of the 20th century. The study is a retrospective analysis from a total sample of 2,200 deliveries, 2,085 of which were born alive and 171 of which did not survive to the 20th birthday. The potential influences of birthdate of childr…
Seventy‐three nuclear DNA polymorphisms in a Spanish population and a comparison with ten other populations
An anthropologically well-defined Spanish sample from La Alpujarra (SE Spain) was analyzed for 73 nuclear DNA polymorphisms. The population was chosen on the basis of available information on its history and demographic characteristics making it suitable for comparisons with data from North African populations. The Moslem invasion in this area was longer than anywhere in the Iberian Peninsula (more than nine centuries). The markers analyzed have …
Stillbirth Pattern in an Isolated Mediterranean Population: La Alpujarra, Spain
This study attempted to analyze the effect of several factors on the stillbirth pattern in a relatively isolated rural population, La Alpujarra (Spain), during the first half of the 20th century. The study was a retrospective analysis from a total sample of 2199 births to 525 mothers, allowing for birth year of mother, maternal age, parental inbreeding, family size, birth order, sex, single/twin delivery, and birth interval. Binomial probability …
Variation of 1 7 RFLP markers on chromosome 1 3 in Southeastern Spain
The allele frequency distribution of 17 nuclear DNA restriction polymorphisms at 15 loci on chromosome 13 was examined in a sample of 70 unrelated autochthonous individuals from La Alpujarra rural mountainous region in Southeastern Spain. The markers typed, 14 associated with anonymous segments and three located on coding regions, constitute a subset from the battery of the nuclear RFLPs previously proposed for population studies (Bowcock et al. …
Inbreeding incidence on biological fitness in an isolated mediterranean population: La Alta Alpujarra Oriental (southeastern Spain)
The incidence of parental inbreeding on biological fitness was analysed in a sample of the Alpujarrenian population. Fitness was estimated as the fertility and offspring viability from conception to reproductive age. The analysed sample represents about 45% of the population from the Alta Alpujarra Oriental in southeastern Spain, and includes 847 families and 2916 pregnancies. The results showed slightly higher reproduction in consanguineous marr…
Stillbirth Pattern in an Isolated Mediterranean Population: La Alpujarra, Spain
This study attempted to analyze the effect of several factors on the stillbirth pattern in a relatively isolated rural population, La Alpujarra (Spain), during the first half of the 20th century. The study was a retrospective analysis from a total sample of 2199 births to 525 mothers, allowing for birth year of mother, maternal age, parental inbreeding, family size, birth order, sex, single/twin delivery, and birth interval. Binomial probability …
Inbreeding incidence on biological fitness in an isolated mediterranean population: La Alta Alpujarra Oriental (southeastern Spain)
The incidence of parental inbreeding on biological fitness was analysed in a sample of the Alpujarrenian population. Fitness was estimated as the fertility and offspring viability from conception to reproductive age. The analysed sample represents about 45% of the population from the Alta Alpujarra Oriental in southeastern Spain, and includes 847 families and 2916 pregnancies. The results showed slightly higher reproduction in consanguineous marr…
Variation of 1 7 RFLP markers on chromosome 1 3 in Southeastern Spain
The allele frequency distribution of 17 nuclear DNA restriction polymorphisms at 15 loci on chromosome 13 was examined in a sample of 70 unrelated autochthonous individuals from La Alpujarra rural mountainous region in Southeastern Spain. The markers typed, 14 associated with anonymous segments and three located on coding regions, constitute a subset from the battery of the nuclear RFLPs previously proposed for population studies (Bowcock et al. …
Seventy‐three nuclear DNA polymorphisms in a Spanish population and a comparison with ten other populations
An anthropologically well-defined Spanish sample from La Alpujarra (SE Spain) was analyzed for 73 nuclear DNA polymorphisms. The population was chosen on the basis of available information on its history and demographic characteristics making it suitable for comparisons with data from North African populations. The Moslem invasion in this area was longer than anywhere in the Iberian Peninsula (more than nine centuries). The markers analyzed have …
Stillbirth Pattern in an Isolated Mediterranean Population: La Alpujarra, Spain
This study attempted to analyze the effect of several factors on the stillbirth pattern in a relatively isolated rural population, La Alpujarra (Spain), during the first half of the 20th century. The study was a retrospective analysis from a total sample of 2199 births to 525 mothers, allowing for birth year of mother, maternal age, parental inbreeding, family size, birth order, sex, single/twin delivery, and birth interval. Binomial probability …
Factors Influencing Prereproductive Mortality in the Isolated and Preindustrial Western Mediterranean Population of La Alpujarra, 1900–1950
We study the effects of several variables on the prereproductive mortality pattern in the isolated and rural population of La Alpujarra, located on the western Mediterranean coast (southeast Spain), in the first half of the 20th century. The study is a retrospective analysis from a total sample of 2,200 deliveries, 2,085 of which were born alive and 171 of which did not survive to the 20th birthday. The potential influences of birthdate of childr…
STR genetic diversity in a Mediterranean population from the south of the Iberian Peninsula
Sixteen Y-chromosomal short tandem repeats (STRs) (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635 and GATA H4.1) were typed in DNA samples from 52 unrelated men and 15 autosomal STRs (CSF1PO, D2S1338, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D19S433, D21S11, FGA, TH01, TPOX, vWA) were also studied for a group of 90 individuals (men and women) from the sam…
Genetic differences among North African Berber and Arab-speaking populations revealed by Y-STR diversity
Y-chromosome STR polymorphisms are inherited in a haploid state which makes them a powerful tool for easy tracing of paternal lineage and for use in human population evolutionary studies. North-African Y chromosomal diversity has traditionally been studied in order to find genetic and geographic associations as well as to test how natural and cultural barriers have affected the degree of genetic flow not only within North Africa but also in a wid…
North African genetic variation of cytochrome and sulfotransferase genes
This review is focused on the genetic variation of sulfotransferases (SULTs) and cytochromes (CYPs) genes among different ethnic groups, mainly focusing in variation in North African populations. Polymorphisms of SULTs and CYPs proteins are associated with altered enzymatic activity and physical characteristics. Single nucleotide polymorphisms (SNP) in these genes have shown relevant ethnic differences among Sub-Saharan African and European group…
A Multicentre and stratified study of the attitude of medical students towards organ donation in Spain
Spanish medical students generally have a favourable attitude towards organ donation, although 20% are not in favour
UDP-glucuronosyltransferase genetic variation in North African populations: A comparison with African and European data
North African populations show a high frequency of carriers of UGT2B15 523Thr , a variant linked to an increased risk of prostate cancer. High Atlas Moroccans and Algerians show low frequency of UGT2B17 del , a variant associated with high concentrations of testosterone and oestradiol
Worldwide distribution of genetic factors related to severity of Covid-19 infection
Considering the caveats of PRS transferability across ethnicities, our analysis showed that American populations present the highest genetic risk score, hence potentially higher propensity, for COVID-19 severity. Independent validation is warranted with additional summary statistics and phenotype data
Biology (9 works) · Demography (8 works) · Demography (8 works) · Population (8 works) · Evolutionary biology (6 works) · Gene (6 works) · Genetics (6 works) · Allele (5 works) · Allele frequency (4 works) · Forensic and Genetic Research (4 works)