A I Kozlov
Biographic Data
| ID | 48966 |
|---|---|
| NAME | A I Kozlov |
| GIVEN NAMES | A I |
| FAMILY NAME | Kozlov |
| SIGNATURE | KOZLOV A I |
| AFFILIATIONS | National Research University Higher School of Economics |
| ORCID | 0000-0002-6710-4862 |
| VERIFIED | Yes |
| TOTAL WORKS | 25 |
| TOTAL CITATIONS | 7 |
| AUTHOR COUNT | 25 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1998 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 2 |
The long journey from anatomical anthropology to variant anatomy
Introduction. Anatomical anthropology is a field of study that emerged in the last third of the 19th century to study the variability of human organ structure, considering body type and racial, ethnic, and social affiliation. The purpose of this study was to review the history of the development of anatomical anthropology with a focus on the stages that led to the formation of the concept of typical and variant anatomy. Materials and methods. Thi…
The concept of adaptive types in modern human ecology research
Introduction. According to the concept of adaptive types proposed about 50 years ago [Alekseeva, 1972, 1977], representatives of different groups and races in similar living conditions independently (convergently) develop close adaptive norms of morpho-physiological complexes that ensure stability in given ecological environment. Today, this concept is widely used in anthropology and human ecology although its important applied and predictive asp…
Genetic Determinants of Carbohydrate Metabolism: Intra- And Interethnic Variability of the Lactase Lct, Trehalase Treh and Sucrase-Isomaltase Si Genes in the Evenki and Other Indigenous Peoples of Sib…
Introduction. The authors consider the features of genetic determinants of disaccharide assimilation as the corollary of adaptation to the environment. The aim of the study was to assess the polymorphism of the genes that determine activity of disaccharidase enzymes lactase (LCT, rs4988235), trehalase (TREH, rs2276064) and sucrase-isomaltase (SI, rs781470490) in different territorial groups of Evenks. Materials and methods. Biomaterial samples fr…
Variability of UCP1 and UCP3 uncoupling protein genes in relation to climate in indigenous populations of Siberia and the Far East
Introduction. Several studies have demonstrated a correlation between variations in genes regulating human uncoupling proteins (UCP) and environmental factors. However, information on the intra- and interpopulation diversity of allele and genotype frequencies of UCP1 and UCP3 within the territory of Russia remains insufficient. This study aims to investigate the intra- and inter-ethnic variability of genetic determinants of activity of uncoupling…
Modern interpretations of evolutionary, anthropological and ecological aspects of the “thrifty genotype” hypothesis
Introduction. There are a number of genes, individual alleles of which or their combinations make the carrier susceptible to the disease. In the case of type 2 diabetes, obesity, and metabolic syndrome, the hypothesis of a “thrifty genotype” was put forward as a combination of gene alleles that provided their carriers with advantages in the prehistoric and historical past, but provoked morbidity now. Such a genotype should have previously been un…
Cline in genetic diversity of trehalase deficiency determinants in populations of Southern Siberia, Kazakhstan, Central Asia, and Mongolia
Introduction. Trehalose or mushroom sugar has been increasingly used in the food industry in the past decades. To be absorbed in the human intestine, trehalose needs to be broken down by an enzyme known as trehalase. Today, it is known that the G→A substitution in the rs2276064 locus of the TREH gene results in the reduced activity of this enzyme. The aim of this study was to analyze the frequency of TREH (rs2276064) alleles and genotypes in the …
Sucrose malabsorption confirms the distinctive genetic history of the Inuit
Introduction. A dinucleotide deletion of AG at the rs781470490 locus of the SI gene (SI delAG variant) causes dysfunction of the sucrase-isomaltase enzyme and the inability to digest sugar. The deletion frequency in the world is 0.0021%, while among the Inuit (Eskimo) it reaches 17–20%. Research hypothesis: the SI delAG variant is common in all the populations of indigenous northerners. The study aimed to ascertain the prevalence of the SI delAG …
The peculiarity of sub-ethnic groups of Nenets in genetic determinants of the metabolism of sucrose, trehalose and lactose
Introduction. The diet of indigenous northerners is changing significantly on account of the rapid growth in volume and variety of consummated food sugars. Concurrently, an arrow of northern aboriginal groups are known to have an increased percentage of genetically determined disorders of disaccharide metabolism. The study aimed to assess the polymorphism of genes and alleles that determine production or activity of sucrase-isomaltase, trehalase …
Changes in the reproductive behavior of women in Komi-Permyak Okrug, Perm Kray, in 1987–2020
Introduction. Rosstat discontinued registering ethnic belonging of subjects in their data on births, thus hindering the monitoring of changes in reproductive behavior and demographic transition in ethnic groups. Medical records can partially compensate for this deficit. The aim of the study was to reveal the changes in the reproductive behavior of Komi-Permyak and Russian women living in rural settlements and a town in Komi-Permyak Okrug (KPO) fr…
Overweight and obesity in schoolchildren of Perm Krai
The changes in the prevalence of overweight and obesity in countries with different levels of economic development are contra-directional. Information on the matter in the regions of the Russian Federation is incomplete, making monitoring difficult. The weight status of the child and youth population is of particular interest. The study aimed to assess the prevalence of overweight and obesity in school-age children living in rural settlements, a …
Overweight and obesity among rural schoolchildren of the Russian Arctic and North in 1994-2019
BACKGROUND: There was not enough information on the spread of obesity among schoolchildren in rural settlements and small towns of Northern Russia in recent years. This study aimed to trace the prevalence of overweight and obesity in children aged 617 years living in rural areas of Northern Russia between 1994 and 2019.METHODS: Data, including sex, age, body weight, and stature, were collected during regular medical examinations of 7548 children …
Farinaceous and starchy foods in the diet of the indigenous people of the high-latitude and Arctic regions of Russia: Tradition and Modernity
The object of the study is the indigenous population of the North and the Arctic of the Russian Federation. The subject of the study is changes in nutrition during transition from the traditional to modernized lifestyle. The purpose of the study is to consider the risk to the health of the northerners in the quantitative and qualitative changes in the consumption of flour and starch-containing products. The consumption of bread products and starc…
Formation of adaptive types as a process of microevolution
The study populations have been grouped into two clusters. The first constituted the ethnic groups that are anthropologically affine but differ in adaptive types and husbandry practices. The second included the anthropologically unrelated ethnic groups having similar environment economy systems and adaptive types. We analyzed the genotype and allele frequencies of the metabolism-associated APOE, LCT, TREH, UCP1 genes, and Fok1 and BsmI polymorphi…
Gene pool reflects traditional diet peculiarities of ethnic groups practicing taiga-forest type of economy
ae
Birth weight relation to social and biological factors
()
The divergence of genetic complexes in anthropologically related populations with different types of management of natural resources
(-ae), . . 127 - 134 -ae. APOE, LCT, UCP1 VDR
Anthropological and ecological specificity of polymorphism in genes related to bone tissue metabolism (as exemplified by the Shors people)
АНТРОПОЭКОЛОГИЧЕСКАЯ СПЕЦИФИКА ПОЛИМОРФИЗМА ГЕНОВ, ВЛИЯЮЩИХ НА МЕТАБОЛИЗМ КОСТНОЙ ТКАНИ (НА ПРИМЕРЕ ПОПУЛЯЦИИ ШОРЦЕВ
Secular trends in height and pelvic size of Ob Ugrians (Khanty and Mansi)
Introduction.Long term changes in the body height and female pelvic width of North-Western Siberia indigenous people -the Nothern Khanty and Sosva Mansi, were the subject matter of the study.Materials and discussion.The indices under examination were averaged by decade to trace the changes from the 1860s to 1990s.Through the birth cohorts (BiCo) from the 1860s to 1930s, the stature of Ob Ugrians did not alter significantly.In successive generatio…
Overweight and obesity in children 7-17 years old in Northwestern Russia and the Cis-Urals
30
Historical aspects of the constitution type theory development in Western Europe and the USA
К ИСТОРИИ РАЗВИТИЯ УЧЕНИЯ О КОНСТИТУЦИИ В ЗАПАДНОЙ ЕВРОПЕ И США (ПЕРВАЯ ПОЛОВИНА XX ВЕКА
Secular trends in average height and age at menarche of ethnic Russians and Komi-Permyaks of the Permsky Krai, Russia
The aim was to describe the changes in body size and age at menarche in anthropologically distinct ethnic groups - Komi-Permyaks (KP) and Russians (RU) - of Permsky Krai that occurred in the last century, with a special concern to the urban-rural differences. The comparison of the 1861 - 1865 and 1990 birth cohorts (BiCo) revealed following results. In RU rural males the increase in stature (ST) was 10.8 cm (p < 0.001). The chest circumference ha…
A human derived SSADH coding variant is replacing the ancestral allele shared with primates
The analysis of robust correlations based on a large panel of populations is potentially able to identify clusters of genomic regions or genes showing co-evolution of the frequencies of derived alleles
Genetic and environmental influence on the asymmetry of dermatoglyphic traits
Genetic and environmental influence on the asymmetry of dermatoglyphic traits
Fluctuating asymmetry (FA) is defined as random deviations from bilateral symmetry of the body. Thus, its magnitude is often used to evaluate developmental homeostasis. In this study we evaluate the following hypotheses: 1) FA of dermatoglyphic traits has a significant genetic component; 2) prenatal maternal environment (PME) has a significant effect on the FA of dermatoglyphic traits in developmentally healthy individuals; and 3) genetic or envi…
The Morphological Peculiarities of the Populations of Eastern and Western Siberia
The influence of climatic-geographic factors on the Russians of Western and Eastern Siberia and on the Buryats of Eastern Siberia was investigated. A comparison of important ecotypological characteristics such as body mass index and topography of subcutaneous adipose tissue confirmed better adaptability in the Russian males than the females to the stressful influence of the severe continental climate of Eastern Siberia. It suggests the possibilit…
Secular trends in average height and age at menarche of ethnic Russians and Komi-Permyaks of the Permsky Krai, Russia
The aim was to describe the changes in body size and age at menarche in anthropologically distinct ethnic groups - Komi-Permyaks (KP) and Russians (RU) - of Permsky Krai that occurred in the last century, with a special concern to the urban-rural differences. The comparison of the 1861 - 1865 and 1990 birth cohorts (BiCo) revealed following results. In RU rural males the increase in stature (ST) was 10.8 cm (p < 0.001). The chest circumference ha…
The Morphological Peculiarities of the Populations of Eastern and Western Siberia
The influence of climatic-geographic factors on the Russians of Western and Eastern Siberia and on the Buryats of Eastern Siberia was investigated. A comparison of important ecotypological characteristics such as body mass index and topography of subcutaneous adipose tissue confirmed better adaptability in the Russian males than the females to the stressful influence of the severe continental climate of Eastern Siberia. It suggests the possibilit…
The Morphological Peculiarities of the Populations of Eastern and Western Siberia
The influence of climatic-geographic factors on the Russians of Western and Eastern Siberia and on the Buryats of Eastern Siberia was investigated. A comparison of important ecotypological characteristics such as body mass index and topography of subcutaneous adipose tissue confirmed better adaptability in the Russian males than the females to the stressful influence of the severe continental climate of Eastern Siberia. It suggests the possibilit…
Genetic and environmental influence on the asymmetry of dermatoglyphic traits
Genetic and environmental influence on the asymmetry of dermatoglyphic traits
Fluctuating asymmetry (FA) is defined as random deviations from bilateral symmetry of the body. Thus, its magnitude is often used to evaluate developmental homeostasis. In this study we evaluate the following hypotheses: 1) FA of dermatoglyphic traits has a significant genetic component; 2) prenatal maternal environment (PME) has a significant effect on the FA of dermatoglyphic traits in developmentally healthy individuals; and 3) genetic or envi…
A human derived SSADH coding variant is replacing the ancestral allele shared with primates
The analysis of robust correlations based on a large panel of populations is potentially able to identify clusters of genomic regions or genes showing co-evolution of the frequencies of derived alleles
Secular trends in average height and age at menarche of ethnic Russians and Komi-Permyaks of the Permsky Krai, Russia
The aim was to describe the changes in body size and age at menarche in anthropologically distinct ethnic groups - Komi-Permyaks (KP) and Russians (RU) - of Permsky Krai that occurred in the last century, with a special concern to the urban-rural differences. The comparison of the 1861 - 1865 and 1990 birth cohorts (BiCo) revealed following results. In RU rural males the increase in stature (ST) was 10.8 cm (p < 0.001). The chest circumference ha…
Secular trends in height and pelvic size of Ob Ugrians (Khanty and Mansi)
Introduction.Long term changes in the body height and female pelvic width of North-Western Siberia indigenous people -the Nothern Khanty and Sosva Mansi, were the subject matter of the study.Materials and discussion.The indices under examination were averaged by decade to trace the changes from the 1860s to 1990s.Through the birth cohorts (BiCo) from the 1860s to 1930s, the stature of Ob Ugrians did not alter significantly.In successive generatio…
Overweight and obesity in children 7-17 years old in Northwestern Russia and the Cis-Urals
30
Historical aspects of the constitution type theory development in Western Europe and the USA
К ИСТОРИИ РАЗВИТИЯ УЧЕНИЯ О КОНСТИТУЦИИ В ЗАПАДНОЙ ЕВРОПЕ И США (ПЕРВАЯ ПОЛОВИНА XX ВЕКА
Anthropological and ecological specificity of polymorphism in genes related to bone tissue metabolism (as exemplified by the Shors people)
АНТРОПОЭКОЛОГИЧЕСКАЯ СПЕЦИФИКА ПОЛИМОРФИЗМА ГЕНОВ, ВЛИЯЮЩИХ НА МЕТАБОЛИЗМ КОСТНОЙ ТКАНИ (НА ПРИМЕРЕ ПОПУЛЯЦИИ ШОРЦЕВ
Gene pool reflects traditional diet peculiarities of ethnic groups practicing taiga-forest type of economy
ae
Birth weight relation to social and biological factors
()
The divergence of genetic complexes in anthropologically related populations with different types of management of natural resources
(-ae), . . 127 - 134 -ae. APOE, LCT, UCP1 VDR
Formation of adaptive types as a process of microevolution
The study populations have been grouped into two clusters. The first constituted the ethnic groups that are anthropologically affine but differ in adaptive types and husbandry practices. The second included the anthropologically unrelated ethnic groups having similar environment economy systems and adaptive types. We analyzed the genotype and allele frequencies of the metabolism-associated APOE, LCT, TREH, UCP1 genes, and Fok1 and BsmI polymorphi…
The peculiarity of sub-ethnic groups of Nenets in genetic determinants of the metabolism of sucrose, trehalose and lactose
Introduction. The diet of indigenous northerners is changing significantly on account of the rapid growth in volume and variety of consummated food sugars. Concurrently, an arrow of northern aboriginal groups are known to have an increased percentage of genetically determined disorders of disaccharide metabolism. The study aimed to assess the polymorphism of genes and alleles that determine production or activity of sucrase-isomaltase, trehalase …
Changes in the reproductive behavior of women in Komi-Permyak Okrug, Perm Kray, in 1987–2020
Introduction. Rosstat discontinued registering ethnic belonging of subjects in their data on births, thus hindering the monitoring of changes in reproductive behavior and demographic transition in ethnic groups. Medical records can partially compensate for this deficit. The aim of the study was to reveal the changes in the reproductive behavior of Komi-Permyak and Russian women living in rural settlements and a town in Komi-Permyak Okrug (KPO) fr…
Overweight and obesity in schoolchildren of Perm Krai
The changes in the prevalence of overweight and obesity in countries with different levels of economic development are contra-directional. Information on the matter in the regions of the Russian Federation is incomplete, making monitoring difficult. The weight status of the child and youth population is of particular interest. The study aimed to assess the prevalence of overweight and obesity in school-age children living in rural settlements, a …
Overweight and obesity among rural schoolchildren of the Russian Arctic and North in 1994-2019
BACKGROUND: There was not enough information on the spread of obesity among schoolchildren in rural settlements and small towns of Northern Russia in recent years. This study aimed to trace the prevalence of overweight and obesity in children aged 617 years living in rural areas of Northern Russia between 1994 and 2019.METHODS: Data, including sex, age, body weight, and stature, were collected during regular medical examinations of 7548 children …
Farinaceous and starchy foods in the diet of the indigenous people of the high-latitude and Arctic regions of Russia: Tradition and Modernity
The object of the study is the indigenous population of the North and the Arctic of the Russian Federation. The subject of the study is changes in nutrition during transition from the traditional to modernized lifestyle. The purpose of the study is to consider the risk to the health of the northerners in the quantitative and qualitative changes in the consumption of flour and starch-containing products. The consumption of bread products and starc…
Modern interpretations of evolutionary, anthropological and ecological aspects of the “thrifty genotype” hypothesis
Introduction. There are a number of genes, individual alleles of which or their combinations make the carrier susceptible to the disease. In the case of type 2 diabetes, obesity, and metabolic syndrome, the hypothesis of a “thrifty genotype” was put forward as a combination of gene alleles that provided their carriers with advantages in the prehistoric and historical past, but provoked morbidity now. Such a genotype should have previously been un…
Cline in genetic diversity of trehalase deficiency determinants in populations of Southern Siberia, Kazakhstan, Central Asia, and Mongolia
Introduction. Trehalose or mushroom sugar has been increasingly used in the food industry in the past decades. To be absorbed in the human intestine, trehalose needs to be broken down by an enzyme known as trehalase. Today, it is known that the G→A substitution in the rs2276064 locus of the TREH gene results in the reduced activity of this enzyme. The aim of this study was to analyze the frequency of TREH (rs2276064) alleles and genotypes in the …
Sucrose malabsorption confirms the distinctive genetic history of the Inuit
Introduction. A dinucleotide deletion of AG at the rs781470490 locus of the SI gene (SI delAG variant) causes dysfunction of the sucrase-isomaltase enzyme and the inability to digest sugar. The deletion frequency in the world is 0.0021%, while among the Inuit (Eskimo) it reaches 17–20%. Research hypothesis: the SI delAG variant is common in all the populations of indigenous northerners. The study aimed to ascertain the prevalence of the SI delAG …
The concept of adaptive types in modern human ecology research
Introduction. According to the concept of adaptive types proposed about 50 years ago [Alekseeva, 1972, 1977], representatives of different groups and races in similar living conditions independently (convergently) develop close adaptive norms of morpho-physiological complexes that ensure stability in given ecological environment. Today, this concept is widely used in anthropology and human ecology although its important applied and predictive asp…
Genetic Determinants of Carbohydrate Metabolism: Intra- And Interethnic Variability of the Lactase Lct, Trehalase Treh and Sucrase-Isomaltase Si Genes in the Evenki and Other Indigenous Peoples of Sib…
Introduction. The authors consider the features of genetic determinants of disaccharide assimilation as the corollary of adaptation to the environment. The aim of the study was to assess the polymorphism of the genes that determine activity of disaccharidase enzymes lactase (LCT, rs4988235), trehalase (TREH, rs2276064) and sucrase-isomaltase (SI, rs781470490) in different territorial groups of Evenks. Materials and methods. Biomaterial samples fr…
Variability of UCP1 and UCP3 uncoupling protein genes in relation to climate in indigenous populations of Siberia and the Far East
Introduction. Several studies have demonstrated a correlation between variations in genes regulating human uncoupling proteins (UCP) and environmental factors. However, information on the intra- and interpopulation diversity of allele and genotype frequencies of UCP1 and UCP3 within the territory of Russia remains insufficient. This study aims to investigate the intra- and inter-ethnic variability of genetic determinants of activity of uncoupling…
The long journey from anatomical anthropology to variant anatomy
Introduction. Anatomical anthropology is a field of study that emerged in the last third of the 19th century to study the variability of human organ structure, considering body type and racial, ethnic, and social affiliation. The purpose of this study was to review the history of the development of anatomical anthropology with a focus on the stages that led to the formation of the concept of typical and variant anatomy. Materials and methods. Thi…
Biology (17 works) · Geography (12 works) · Ecology (10 works) · Demography (9 works) · Genetics (9 works) · Gene (8 works) · Genotype (8 works) · Medicine (8 works) · Digestive system and related health (7 works) · Evolutionary biology (7 works)