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Rafaelle L Lancelotta

Biographic Data

ID4896940
NAMERafaelle L Lancelotta
GIVEN NAMESRafaelle L
FAMILY NAMELancelotta
SIGNATURELANCELOTTA R L
AFFILIATIONSThe Ohio State University
ORCID0000-0002-7789-3463
VERIFIEDYes
TOTAL WORKS9
TOTAL CITATIONS1
AUTHOR COUNT9
EDITOR COUNT0
FIRST PUBLICATION YEAR2020
LATEST PUBLICATION YEAR2026
H-INDEX1
  • Development and assessment of a psychedelic-assisted therapy music playlist for clinical trials

    Open Access•Rafaelle L Lancelotta, Paul Nagib et al.•ARTICLE•Journal of Psychedelic Studies•2026•References: 11

    Background and Purpose Music plays a central role in psychedelic-assisted therapy, yet few methodologies exist to create and assess therapeutic playlists. This study aimed to illustrate a methodology for developing and evaluating a music playlist for a clinical psilocybin trial using an integrative framework grounded in theory, intentionality, and metrics. Methods A playlist was designed based on clinical experience, phenomenological data, and th…

  • Reactivations Associated with the Use of 5-MeO-DMT Among Spanish-Speaking Individuals

    Ana María Ortiz Bernal, Charles L Raison et al.•ARTICLE•Journal of Psychoactive Drugs•2025

    5-Methoxy- N,N -dimethyltryptamine (5-MeO-DMT) is a psychedelic gaining interest as a potential mental health treatment. However, a poorly characterized phenomenon termed reactivation (similar to "flashbacks") is commonly reported with 5-MeO-DMT use and merits investigation. This study examined the prevalence, predictors, and emotional valence of reactivations among Spanish-speaking individuals. Specifically, we investigated whether gender, time …

  • Exploring Self-Reported Effects of Naturalistic Psychedelic Use Among Gender and Sexual Minorities

    Open Access•Rafaelle L Lancelotta, Meghan A Dellacrosse et al.•ARTICLE•Journal of Psychoactive Drugs•2025

    This study investigated subjective psychedelic experiences in the global LGBTQIA+ population. Using validated measures of acute psychedelic effects, psychological flexibility, gender and sexual identity attitudes, adverse experiences, and mental health, we examined self-reported changes in identity and mental health outcomes following psychedelic use. A total of 346 individuals completed the survey. The sample was predominantly White (78.6%) with…

  • Translation and Initial Psychometric Evaluation of Spanish Versions of Three Psychedelic Acute Effects Measures

    Open Access•A K Davis, Christopher Timmermann et al.•ARTICLE•Journal of Psychoactive Drugs•2023

    This study translated and tested the psychometric properties of acute psychedelic effects measures among Spanish-speaking people. The Psychological Insight Questionnaire (PIQ), Challenging Experiences Questionnaire (CEQ), and Mystical Experiences Questionnaire (MEQ) were translated before being incorporated into a web-based survey. We recruited native Spanish-speakers ( N = 442; M age = 30.8, SD = 10.9; Latino/Latina = 62%; Hispanic = 91.4%; male…

  • Reactivations after 5-methoxy-N,N-dimethyltryptamine use in naturalistic settings

    Open Access•Ana María Ortiz Bernal, Charles L Raison et al.•ARTICLE•Frontiers in Psychiatry•2022

    These findings suggest that reactivation phenomena, in this particular sample may most often represent a neutral or positive byproduct of the acute 5-MeO-DMT experience. More information is needed to best identify individuals most likely to experience a reactivation as a negative event to prevent such potential challenging outcomes

  • A Meta-Analysis of Placebo-Controlled Trials of Psychedelic-Assisted Therapy

    Jason B Luoma, Christina Chwyl et al.•ARTICLE•Journal of Psychoactive Drugs•2020

    After a two-decade hiatus in which research on psychedelics was essentially halted, placebo-controlled clinical trials of psychedelic-assisted therapy for mental health conditions have begun to be published. We identified nine randomized, placebo-controlled clinical trials of psychedelic-assisted therapy published since 1994. Studies examined psilocybin, LSD (lysergic acid diethylamide), ayahuasca (which contains a combination of N,N-dimethyltryp…

  • Use of Benefit Enhancement Strategies among 5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) Users

    Rafaelle L Lancelotta, Rafael L Lancelotta et al.•ARTICLE•Journal of Psychoactive Drugs•2020

    5-Methoxy- N,N -Dimethyltryptamine (5-MeO-DMT) is a potent, fast-acting psychedelic. Anecdotal reports from 5-MeO-DMT users suggest that they employ a variety of benefit enhancement (BE) strategies aimed to increase positive effects and decrease any potential challenging effects of the substance, but no empirical study has investigated this claim. We examined the prevalence of BE strategy use using secondary data from a survey of 5-MeO-DMT users …

  • Inhaled 5-methoxy-N,N-dimethyltryptamine

    Open Access•Nathan D Sepeda, John M Clifton et al.•ARTICLE•Journal of Psychedelic Studies•2020•Cited by: 1•References: 32

    Background and aims 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a potent, short-acting psychedelic that produces strong hallucinogenic effects. The association between the context (i.e., set and setting) of 5-MeO-DMT use and the acute and enduring effects of the substance is unknown. Therefore, this study examined these associations using secondary data from two cross-sectional survey studies. Methods The acute and enduring effects of inhaled…

  • A comparison of reactivation experiences following vaporization and intramuscular injection (IM) of synthetic 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) in a naturalistic setting

    Open Access•M V Uthaug, R Lancelotta et al.•ARTICLE•Journal of Psychedelic Studies•2020•References: 41

    BackgroundPrevious research suggests a therapeutic potential of5-methoxy-N,N-dimethyltryptamine(5-MeO-DMT). However, online anecdotal reports have described a phenomenon following cessation of the acute effects of 5-MeO-DMT use which has been termedreactivation(i.e., re-experiencing ["flashback"]). To date, no research has investigated whether different routes of administration may confer different reactivation rates, effects and experiences.Aims…

  • Inhaled 5-methoxy-N,N-dimethyltryptamine

    Open Access•Nathan D Sepeda, John M Clifton et al.•ARTICLE•Journal of Psychedelic Studies•2020•Cited by: 1•References: 32

    Background and aims 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a potent, short-acting psychedelic that produces strong hallucinogenic effects. The association between the context (i.e., set and setting) of 5-MeO-DMT use and the acute and enduring effects of the substance is unknown. Therefore, this study examined these associations using secondary data from two cross-sectional survey studies. Methods The acute and enduring effects of inhaled…

  • A Meta-Analysis of Placebo-Controlled Trials of Psychedelic-Assisted Therapy

    Jason B Luoma, Christina Chwyl et al.•ARTICLE•Journal of Psychoactive Drugs•2020

    After a two-decade hiatus in which research on psychedelics was essentially halted, placebo-controlled clinical trials of psychedelic-assisted therapy for mental health conditions have begun to be published. We identified nine randomized, placebo-controlled clinical trials of psychedelic-assisted therapy published since 1994. Studies examined psilocybin, LSD (lysergic acid diethylamide), ayahuasca (which contains a combination of N,N-dimethyltryp…

  • Use of Benefit Enhancement Strategies among 5-Methoxy-N,N-Dimethyltryptamine (5-MeO-DMT) Users

    Rafaelle L Lancelotta, Rafael L Lancelotta et al.•ARTICLE•Journal of Psychoactive Drugs•2020

    5-Methoxy- N,N -Dimethyltryptamine (5-MeO-DMT) is a potent, fast-acting psychedelic. Anecdotal reports from 5-MeO-DMT users suggest that they employ a variety of benefit enhancement (BE) strategies aimed to increase positive effects and decrease any potential challenging effects of the substance, but no empirical study has investigated this claim. We examined the prevalence of BE strategy use using secondary data from a survey of 5-MeO-DMT users …

  • Inhaled 5-methoxy-N,N-dimethyltryptamine

    Open Access•Nathan D Sepeda, John M Clifton et al.•ARTICLE•Journal of Psychedelic Studies•2020•Cited by: 1•References: 32

    Background and aims 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a potent, short-acting psychedelic that produces strong hallucinogenic effects. The association between the context (i.e., set and setting) of 5-MeO-DMT use and the acute and enduring effects of the substance is unknown. Therefore, this study examined these associations using secondary data from two cross-sectional survey studies. Methods The acute and enduring effects of inhaled…

  • A comparison of reactivation experiences following vaporization and intramuscular injection (IM) of synthetic 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) in a naturalistic setting

    Open Access•M V Uthaug, R Lancelotta et al.•ARTICLE•Journal of Psychedelic Studies•2020•References: 41

    BackgroundPrevious research suggests a therapeutic potential of5-methoxy-N,N-dimethyltryptamine(5-MeO-DMT). However, online anecdotal reports have described a phenomenon following cessation of the acute effects of 5-MeO-DMT use which has been termedreactivation(i.e., re-experiencing ["flashback"]). To date, no research has investigated whether different routes of administration may confer different reactivation rates, effects and experiences.Aims…

  • Reactivations after 5-methoxy-N,N-dimethyltryptamine use in naturalistic settings

    Open Access•Ana María Ortiz Bernal, Charles L Raison et al.•ARTICLE•Frontiers in Psychiatry•2022

    These findings suggest that reactivation phenomena, in this particular sample may most often represent a neutral or positive byproduct of the acute 5-MeO-DMT experience. More information is needed to best identify individuals most likely to experience a reactivation as a negative event to prevent such potential challenging outcomes

  • Translation and Initial Psychometric Evaluation of Spanish Versions of Three Psychedelic Acute Effects Measures

    Open Access•A K Davis, Christopher Timmermann et al.•ARTICLE•Journal of Psychoactive Drugs•2023

    This study translated and tested the psychometric properties of acute psychedelic effects measures among Spanish-speaking people. The Psychological Insight Questionnaire (PIQ), Challenging Experiences Questionnaire (CEQ), and Mystical Experiences Questionnaire (MEQ) were translated before being incorporated into a web-based survey. We recruited native Spanish-speakers ( N = 442; M age = 30.8, SD = 10.9; Latino/Latina = 62%; Hispanic = 91.4%; male…

  • Reactivations Associated with the Use of 5-MeO-DMT Among Spanish-Speaking Individuals

    Ana María Ortiz Bernal, Charles L Raison et al.•ARTICLE•Journal of Psychoactive Drugs•2025

    5-Methoxy- N,N -dimethyltryptamine (5-MeO-DMT) is a psychedelic gaining interest as a potential mental health treatment. However, a poorly characterized phenomenon termed reactivation (similar to "flashbacks") is commonly reported with 5-MeO-DMT use and merits investigation. This study examined the prevalence, predictors, and emotional valence of reactivations among Spanish-speaking individuals. Specifically, we investigated whether gender, time …

  • Exploring Self-Reported Effects of Naturalistic Psychedelic Use Among Gender and Sexual Minorities

    Open Access•Rafaelle L Lancelotta, Meghan A Dellacrosse et al.•ARTICLE•Journal of Psychoactive Drugs•2025

    This study investigated subjective psychedelic experiences in the global LGBTQIA+ population. Using validated measures of acute psychedelic effects, psychological flexibility, gender and sexual identity attitudes, adverse experiences, and mental health, we examined self-reported changes in identity and mental health outcomes following psychedelic use. A total of 346 individuals completed the survey. The sample was predominantly White (78.6%) with…

  • Development and assessment of a psychedelic-assisted therapy music playlist for clinical trials

    Open Access•Rafaelle L Lancelotta, Paul Nagib et al.•ARTICLE•Journal of Psychedelic Studies•2026•References: 11

    Background and Purpose Music plays a central role in psychedelic-assisted therapy, yet few methodologies exist to create and assess therapeutic playlists. This study aimed to illustrate a methodology for developing and evaluating a music playlist for a clinical psilocybin trial using an integrative framework grounded in theory, intentionality, and metrics. Methods A playlist was designed based on clinical experience, phenomenological data, and th…

Psychedelics and Drug Studies (9 works) · Psychology (7 works) · Clinical Psychology (6 works) · Clinical Psychology (5 works) · Medicine (5 works) · Chemical synthesis and alkaloids (4 works) · Neurotransmitter Receptor Influence on Behavior (4 works) · Psychiatry (4 works) · Hallucinogen (3 works) · Psilocybin (3 works)

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