Mark A Frye
Biographic Data
| ID | 5059246 |
|---|---|
| NAME | Mark A Frye |
| GIVEN NAMES | Mark A |
| FAMILY NAME | Frye |
| SIGNATURE | FRYE M A |
| AFFILIATIONS | WinnMed |
| ORCID | 0000-0001-6997-4215 |
| VERIFIED | Yes |
| TOTAL WORKS | 8 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 8 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2018 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Leveraging reddit data for context-enhanced synthetic health data generation to identify low self esteem
Low self-esteem (LoST) is a latent yet critical psychosocial risk factor that predisposes individuals to depressive disorders. Although structured tools exist to assess self-esteem, their limited clinical adoption suggests that relevant indicators of LoST remain buried within unstructured clinical narratives. The scarcity of annotated clinical notes impedes the development of natural language processing (NLP) models for its detection. Manual char…
Transcultural Perceptions of Bipolar Disorder in the West African Sub-region
Prediction of medical admissions after psychiatric inpatient hospitalization in bipolar disorder
Our findings support the need to monitor medical comorbidities during clinical decision-making to tailor and implement effective preventive measures in people with BD. Further research with larger sample sizes and prospective cohorts is warranted to replicate these findings and validate the predictive model
Racial differences in pathways to care preceding first episode mania or psychosis
These data are unable to ascertain reasons for shorter duration of psychiatric antecedents and later age of seeking care, and more broadly first age of initial symptom presentation. If symptoms are confirmed to be earlier than first time seeking care in both groups, it would be important to identify barriers that racial minorities face to access timely psychiatric care and optimize early intervention strategies
Comparison of Demographic and Clinical Features of Bipolar Disorder in Persons of African and European Ancestry
Association of Bipolar Disorder With Major Adverse Cardiovascular Events
OBJECTIVE: This study aimed to assess the association of bipolar disorder (BD) with risk of major adverse cardiac events (MACEs) after adjusting for established cardiovascular disease (CVD) risk factors. METHODS: We conducted a population-based historical cohort study using the Rochester Epidemiology Project. Patients older than 30 years with a clinical encounter from 1998 to 2000 with no prior MACE, atrial fibrillation, or heart failure were fol…
Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder
BD+cADHD was associated with a greater number of comorbidities and reduced response to mood stabilizing treatments. The higher ADHD PRS for the BD+cADHD group may reflect a greater influence of genetic factors on early presentation of ADHD symptoms
Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder
Bipolar disorder (BD) is a common, highly heritable neuropsychiatric disease characterized by recurrent episodes of mania and depression. Lithium is the best-established long-term treatment for BD, even though individual response is highly variable. Evidence suggests that some of this variability has a genetic basis. This is supported by the largest genome-wide association study (GWAS) of lithium response to date conducted by the International Co…
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Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder
Bipolar disorder (BD) is a common, highly heritable neuropsychiatric disease characterized by recurrent episodes of mania and depression. Lithium is the best-established long-term treatment for BD, even though individual response is highly variable. Evidence suggests that some of this variability has a genetic basis. This is supported by the largest genome-wide association study (GWAS) of lithium response to date conducted by the International Co…
Association of Bipolar Disorder With Major Adverse Cardiovascular Events
OBJECTIVE: This study aimed to assess the association of bipolar disorder (BD) with risk of major adverse cardiac events (MACEs) after adjusting for established cardiovascular disease (CVD) risk factors. METHODS: We conducted a population-based historical cohort study using the Rochester Epidemiology Project. Patients older than 30 years with a clinical encounter from 1998 to 2000 with no prior MACE, atrial fibrillation, or heart failure were fol…
Clinical and Genetic Correlates of Bipolar Disorder With Childhood-Onset Attention Deficit Disorder
BD+cADHD was associated with a greater number of comorbidities and reduced response to mood stabilizing treatments. The higher ADHD PRS for the BD+cADHD group may reflect a greater influence of genetic factors on early presentation of ADHD symptoms
Racial differences in pathways to care preceding first episode mania or psychosis
These data are unable to ascertain reasons for shorter duration of psychiatric antecedents and later age of seeking care, and more broadly first age of initial symptom presentation. If symptoms are confirmed to be earlier than first time seeking care in both groups, it would be important to identify barriers that racial minorities face to access timely psychiatric care and optimize early intervention strategies
Comparison of Demographic and Clinical Features of Bipolar Disorder in Persons of African and European Ancestry
Prediction of medical admissions after psychiatric inpatient hospitalization in bipolar disorder
Our findings support the need to monitor medical comorbidities during clinical decision-making to tailor and implement effective preventive measures in people with BD. Further research with larger sample sizes and prospective cohorts is warranted to replicate these findings and validate the predictive model
Transcultural Perceptions of Bipolar Disorder in the West African Sub-region
Leveraging reddit data for context-enhanced synthetic health data generation to identify low self esteem
Low self-esteem (LoST) is a latent yet critical psychosocial risk factor that predisposes individuals to depressive disorders. Although structured tools exist to assess self-esteem, their limited clinical adoption suggests that relevant indicators of LoST remain buried within unstructured clinical narratives. The scarcity of annotated clinical notes impedes the development of natural language processing (NLP) models for its detection. Manual char…
Bipolar disorder (7 works) · Bipolar Disorder and Treatment (7 works) · Medicine (5 works) · Psychiatry (5 works) · Epidemiology (4 works) · Psychology (4 works) · Cohort (3 works) · Internal Medicine (3 works) · Adolescent and Pediatric Healthcare (2 works) · Clinical Psychology (2 works)