Kerry J Ressler
Biographic Data
| ID | 5125622 |
|---|---|
| NAME | Kerry J Ressler |
| GIVEN NAMES | Kerry J |
| FAMILY NAME | Ressler |
| SIGNATURE | RESSLER K J |
| AFFILIATIONS | Howard Hughes Medical Institute |
| ORCID | 0000-0002-5158-1103 |
| VERIFIED | Yes |
| TOTAL WORKS | 13 |
| TOTAL CITATIONS | 23 |
| AUTHOR COUNT | 13 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2010 |
| LATEST PUBLICATION YEAR | 2024 |
| H-INDEX | 1 |
Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci
We observed a strong association between H-SMI and a locus that has been consistently and strongly associated with SCZ in multiple studies (6p21.32-p22.1), possibly indicating an involvement of the immune system and the immune response in the development of severe transdiagnostic SMI
Longitudinal associations between five factor model and impulsive personality traits and PTSD symptoms: Findings from the Aurora study
Improved emotion regulation following a trauma-informed CBT-based intervention associates with reduced risk for recidivism in justice-involved emerging adults
Together, these data suggest that adding mental health support and skills training, such as with trauma-informed CBT models, to programs for justice-involved youth may lead to significant improvements in functioning, quality of life, and mental health outcomes
Dynamic Patterns of Threat-Associated Gene Expression in the Amygdala and Blood
Stress and trauma profoundly influence psychiatric biobehavioral outcomes. The identification of treatment and biomarker targets would be accelerated by a broad understanding of the biological responses to these events. The goal of this study was to determine genes responsive to auditory fear conditioning (FC), a well-characterized amygdala-dependent rodent model of threat-exposure, in the presence or absence of prior stress history, providing in…
Cognitive and neural facets of dissociation in a traumatized population
Dissociative phenomena are frequently experienced by psychologically traumatized people. However, little is known about the cognitive profiles of highly dissociative traumatized individuals, and corresponding patterns of neural connectivity when attentional networks are engaged in the context of emotion. One hundred seventeen traumatized women completed the multiscale dissociation inventory (MDI) and neuropsychological testing; MDI scores were us…
A Gene-Based Analysis of Acoustic Startle Latency
Latency of the acoustic startle response is the time required from the presentation of startling auditory stimulus until the startle response is elicited and provides an index of neural processing speed. Latency is prolonged in subjects with schizophrenia compared to controls in some but not all studies and is 68-90% heritable in baseline startle trials. In order to determine the genetic association with latency as a potential inroad into genetic…
Childhood Trauma and Comt Genotype Interact to Increase Hippocampal Activation in Resilient Individuals
Both childhood trauma and a functional catechol-O-methyltransferase (COMT) genetic polymorphism have been associated with posttraumatic stress disorder (PTSD) and depression; however, it is still unclear whether the two interact and how this interaction relates to long-term risk or resilience. Imaging and genotype data were collected on 73 highly traumatized women. DNA extracted from saliva was used to determine COMT genotype (Val/Val, n = 38, Me…
The mediating role of emotion dysregulation and depression on the relationship between childhood trauma exposure and emotional eating
Parental olfactory experience influences behavior and neural structure in subsequent generations
Dark-Enhanced Startle Responses and Heart Rate Variability in a Traumatized Civilian Sample: Putative Sex-Specific Correlates of Posttraumatic Stress Disorder
OBJECTIVE: Trauma is associated with increased risk for anxiety disorders such as posttraumatic stress disorder (PTSD). To further understand biologic mechanisms of PTSD, we examined the dark-enhanced startle response, a psychophysiological correlate of anxiety, and heart rate variability (HRV) in traumatized individuals with and without PTSD. The associations of these measures with PTSD may be sex-specific because of their associations with the …
Perceived neighborhood disorder, community cohesion, and PTSD symptoms among low-income African Americans in an urban health setting
Studies have established a link between contextual factors, such as neighborhood and community environments, and psychopathology. Although these factors have been shown to affect the expression of symptoms of depression and other disorders, little evidence exists of a link between contextual factors and posttraumatic stress disorder (PTSD). The current study tested the relationships among perceived neighborhood disorder (a measure of self-reporte…
Moderating effects of resilience on depression in individuals with a history of childhood abuse or trauma exposure
Substance use, childhood traumatic experience, and Posttraumatic Stress Disorder in an urban civilian population
OBJECTIVE: Exposure to traumatic experiences, especially those occurring in childhood, has been linked to substance use disorders (SUDs), including abuse and dependence. SUDs are also highly comorbid with Posttraumatic Stress Disorder (PTSD) and other mood-related psychopathology. Most studies examining the relationship between PTSD and SUDs have examined veteran populations or patients in substance treatment programs. The present study further e…
Moderating effects of resilience on depression in individuals with a history of childhood abuse or trauma exposure
Substance use, childhood traumatic experience, and Posttraumatic Stress Disorder in an urban civilian population
OBJECTIVE: Exposure to traumatic experiences, especially those occurring in childhood, has been linked to substance use disorders (SUDs), including abuse and dependence. SUDs are also highly comorbid with Posttraumatic Stress Disorder (PTSD) and other mood-related psychopathology. Most studies examining the relationship between PTSD and SUDs have examined veteran populations or patients in substance treatment programs. The present study further e…
Perceived neighborhood disorder, community cohesion, and PTSD symptoms among low-income African Americans in an urban health setting
Studies have established a link between contextual factors, such as neighborhood and community environments, and psychopathology. Although these factors have been shown to affect the expression of symptoms of depression and other disorders, little evidence exists of a link between contextual factors and posttraumatic stress disorder (PTSD). The current study tested the relationships among perceived neighborhood disorder (a measure of self-reporte…
Dark-Enhanced Startle Responses and Heart Rate Variability in a Traumatized Civilian Sample: Putative Sex-Specific Correlates of Posttraumatic Stress Disorder
OBJECTIVE: Trauma is associated with increased risk for anxiety disorders such as posttraumatic stress disorder (PTSD). To further understand biologic mechanisms of PTSD, we examined the dark-enhanced startle response, a psychophysiological correlate of anxiety, and heart rate variability (HRV) in traumatized individuals with and without PTSD. The associations of these measures with PTSD may be sex-specific because of their associations with the …
Parental olfactory experience influences behavior and neural structure in subsequent generations
The mediating role of emotion dysregulation and depression on the relationship between childhood trauma exposure and emotional eating
Childhood Trauma and Comt Genotype Interact to Increase Hippocampal Activation in Resilient Individuals
Both childhood trauma and a functional catechol-O-methyltransferase (COMT) genetic polymorphism have been associated with posttraumatic stress disorder (PTSD) and depression; however, it is still unclear whether the two interact and how this interaction relates to long-term risk or resilience. Imaging and genotype data were collected on 73 highly traumatized women. DNA extracted from saliva was used to determine COMT genotype (Val/Val, n = 38, Me…
A Gene-Based Analysis of Acoustic Startle Latency
Latency of the acoustic startle response is the time required from the presentation of startling auditory stimulus until the startle response is elicited and provides an index of neural processing speed. Latency is prolonged in subjects with schizophrenia compared to controls in some but not all studies and is 68-90% heritable in baseline startle trials. In order to determine the genetic association with latency as a potential inroad into genetic…
Cognitive and neural facets of dissociation in a traumatized population
Dissociative phenomena are frequently experienced by psychologically traumatized people. However, little is known about the cognitive profiles of highly dissociative traumatized individuals, and corresponding patterns of neural connectivity when attentional networks are engaged in the context of emotion. One hundred seventeen traumatized women completed the multiscale dissociation inventory (MDI) and neuropsychological testing; MDI scores were us…
Dynamic Patterns of Threat-Associated Gene Expression in the Amygdala and Blood
Stress and trauma profoundly influence psychiatric biobehavioral outcomes. The identification of treatment and biomarker targets would be accelerated by a broad understanding of the biological responses to these events. The goal of this study was to determine genes responsive to auditory fear conditioning (FC), a well-characterized amygdala-dependent rodent model of threat-exposure, in the presence or absence of prior stress history, providing in…
Improved emotion regulation following a trauma-informed CBT-based intervention associates with reduced risk for recidivism in justice-involved emerging adults
Together, these data suggest that adding mental health support and skills training, such as with trauma-informed CBT models, to programs for justice-involved youth may lead to significant improvements in functioning, quality of life, and mental health outcomes
Genetic risk for hospitalization of African American patients with severe mental illness reveals HLA loci
We observed a strong association between H-SMI and a locus that has been consistently and strongly associated with SCZ in multiple studies (6p21.32-p22.1), possibly indicating an involvement of the immune system and the immune response in the development of severe transdiagnostic SMI
Longitudinal associations between five factor model and impulsive personality traits and PTSD symptoms: Findings from the Aurora study
Psychology (12 works) · Medicine (10 works) · Clinical Psychology (9 works) · Psychiatry (9 works) · Neuroscience (6 works) · Biology (4 works) · Child Abuse and Trauma (4 works) · Gene (4 works) · Population (4 works) · Posttraumatic Stress Disorder Research (4 works)