W RICHARD DUKELOW
Biographic Data
| ID | 5179252 |
|---|---|
| NAME | W RICHARD DUKELOW |
| GIVEN NAMES | W RICHARD |
| FAMILY NAME | DUKELOW |
| SIGNATURE | DUKELOW W R |
| AFFILIATIONS | Michigan State University |
| VERIFIED | No |
| TOTAL WORKS | 16 |
| TOTAL CITATIONS | 0 |
| WORKS AS AUTHOR | 15 |
| WORKS AS EDITOR | 1 |
| FIRST PUBLICATION YEAR | 1972 |
| LATEST PUBLICATION YEAR | 2018 |
| H-INDEX | 0 |
Nonhuman Primate Models for Human Diseases
Incorporation of a GnRH agonist, leuprolide acetate, into regimens with exogenous gonadotropins to produce ovarian stimulation and ovulation in the nonpregnant squirrel monkey
This study was designed to measure the effects of variations in the length of pretreatment with a GnRH agonist, leuprolide acetate (LA), on subsequent follicular development and ovulation. The hypothesis was that the duration of LA suppression of pituitary function does not adversely affect ovarian response to standardized ovulation induction protocols in squirrel monkeys. The first phase determined the dose and duration of LA needed to achieve a…
Reflections on a century of primatology
In vitro fertilization analysis of squirrel monkey oocytes produced by various follicular induction regimens and the incidence of triploidy
An in vitro fertilization system utilizing squirrel monkeys was used to compare follicle‐stimulating hormone, clomiphene citrate and prostaglandin E 1 as follicular induction regimens, analyze culture medium characteristics, and examine the physiological phenomenon of polyspermy. Induction of follicular growth was poor with clomiphene citrate when compared to the control group and increased the incidence of atretic follicles at all levels tested.…
Presidential address
New method for in vivo recording of myometrial activity in the squirrel monkey, Saimiri sciureus
Videolaparoscopy was used to visualize the reproductive tract contractility of the squirrel monkey, Saimiri sciureus . This technique gives information on the nature, direction of propagation, duration, and frequency of contractions. At the times of ovulation, and embryo entry to the uterus, contractile activity was observed in both the uterus and oviduct, with the latter being more frequent. The dominant direction of propagation was towards the …
Immunological response and ovarian histology of squirrel monkeys ( Saimiri sciureus ) immunized with porcine zona pellucida ZP3 (M r = 55,000) macromolecules
ZP3 (M, = 55,000) is the major electrophoretic component of the porcine zona pellucida (ZP). In a continuing assessment of ZP3 as a candidate antigen for contraceptive vaccine development, female squirrel monkeys were immunized with 200 μg ZP3 using either Freund's adjuvant (FA) or muramyl dipeptide (MDP) and the effect of such immunization on ovarian histology examined. Two experimental and three control groups were immunized: Group 1 (n = 4), Z…
Biological Anthropology
Capacitation and the acrosome reaction in squirrel monkey ( Saimiri sciureus ) spermatozoa evaluated by the chlortetracycline fluorescence assay
Capacitation and the acrosome reaction in squirrel monkey seminal spermatozoa diluted in Tyrode's medium (TALP) and TC‐199 were monitored by a chlortetracycline (CTC) fluorescence assay. Four CTC patterns, similar to those found in human sperm, were readily characterized by fluorescent staining on the heads of the spermatozoa. The appearance of the capacitated (CP) pattern was dependent on the concentration of the bovine serum albumin. Acrosomal …
Accumulation of 2‐deoxy‐D‐glucose by primate oocytes fertilized in vitro
The present study was designed to investigate the accumulation of 2‐deoxy‐D‐glucose (2‐DG) by squirrel monkey oocytes fertilized in vitro; to assess the effects of insulin addition to the medium on 2‐DG accumulation; and, finally, to evaluate the use of 2‐DG in viability determinations of oocytes. Accumulation of 2‐DG by unfertilized oocytes from squirrel monkeys was 13.94 fmol/oocyte/3 h and was not affected by the addition of either 10 nM or 1 …
Brief report
The time between administration of human chorionic gonadotropin (hCG) and follicle aspiration was analyzed for alterations in [ 3 H]uridine incorporation [as an indicator of relative synthesis of ribonucleic acid (RNA)] of oocytes from squirrel monkeys and humans. There was a significant decline in both the uptake and incorporation of [ 3 H]uridine in squirrel monkey oocytes by 36 hr following hCG administration to the animals, as compared with 1…
Membership analysis of the first six years of the American Society of Primatologists
American Journal of PrimatologyVolume 4, Issue 4 p. 319-322 Editorial NoteFree Access Membership analysis of the first six years of the American Society of Primatologists W. Richard Dukelow, W. Richard Dukelow ChairmanSearch for more papers by this authorJo Fritz, Jo FritzSearch for more papers by this authorE. A. Muchmore, E. A. MuchmoreSearch for more papers by this authorJ. A. Porter Jr., J. A. Porter Jr.Search for more papers by this authorG.…
Non-surgical (laparoscopic) uterine flushing and egg recovery technique in the squirrel monkey (Saimiri sciureus)
Morphological changes in theSaimiri sciureus ovarian follicles as detected by laparoscopy
Follicular development and ovulation in Macaca fascicularis, Saimiri sciureus and Galago senegalensis
A technique utilizing laparoscopy to determine the precise time of ovulation in three species is described. Determination is based on morphological changes that occur 24 to 36 hours before ovulation. This technique, coupled with mating sessions of short‐duration, has been used to produce precisely defined pregnancies; the implications of this technique in reproduction research and teratology are discussed. A comparison of ovulation times in Macac…
Cyclicity and gestation length ofMacaca fascicularis
No prominent works on this page.
Cyclicity and gestation length ofMacaca fascicularis
Follicular development and ovulation in Macaca fascicularis, Saimiri sciureus and Galago senegalensis
A technique utilizing laparoscopy to determine the precise time of ovulation in three species is described. Determination is based on morphological changes that occur 24 to 36 hours before ovulation. This technique, coupled with mating sessions of short‐duration, has been used to produce precisely defined pregnancies; the implications of this technique in reproduction research and teratology are discussed. A comparison of ovulation times in Macac…
Morphological changes in theSaimiri sciureus ovarian follicles as detected by laparoscopy
Non-surgical (laparoscopic) uterine flushing and egg recovery technique in the squirrel monkey (Saimiri sciureus)
Brief report
The time between administration of human chorionic gonadotropin (hCG) and follicle aspiration was analyzed for alterations in [ 3 H]uridine incorporation [as an indicator of relative synthesis of ribonucleic acid (RNA)] of oocytes from squirrel monkeys and humans. There was a significant decline in both the uptake and incorporation of [ 3 H]uridine in squirrel monkey oocytes by 36 hr following hCG administration to the animals, as compared with 1…
Membership analysis of the first six years of the American Society of Primatologists
American Journal of PrimatologyVolume 4, Issue 4 p. 319-322 Editorial NoteFree Access Membership analysis of the first six years of the American Society of Primatologists W. Richard Dukelow, W. Richard Dukelow ChairmanSearch for more papers by this authorJo Fritz, Jo FritzSearch for more papers by this authorE. A. Muchmore, E. A. MuchmoreSearch for more papers by this authorJ. A. Porter Jr., J. A. Porter Jr.Search for more papers by this authorG.…
Accumulation of 2‐deoxy‐D‐glucose by primate oocytes fertilized in vitro
The present study was designed to investigate the accumulation of 2‐deoxy‐D‐glucose (2‐DG) by squirrel monkey oocytes fertilized in vitro; to assess the effects of insulin addition to the medium on 2‐DG accumulation; and, finally, to evaluate the use of 2‐DG in viability determinations of oocytes. Accumulation of 2‐DG by unfertilized oocytes from squirrel monkeys was 13.94 fmol/oocyte/3 h and was not affected by the addition of either 10 nM or 1 …
Capacitation and the acrosome reaction in squirrel monkey ( Saimiri sciureus ) spermatozoa evaluated by the chlortetracycline fluorescence assay
Capacitation and the acrosome reaction in squirrel monkey seminal spermatozoa diluted in Tyrode's medium (TALP) and TC‐199 were monitored by a chlortetracycline (CTC) fluorescence assay. Four CTC patterns, similar to those found in human sperm, were readily characterized by fluorescent staining on the heads of the spermatozoa. The appearance of the capacitated (CP) pattern was dependent on the concentration of the bovine serum albumin. Acrosomal …
Immunological response and ovarian histology of squirrel monkeys ( Saimiri sciureus ) immunized with porcine zona pellucida ZP3 (M r = 55,000) macromolecules
ZP3 (M, = 55,000) is the major electrophoretic component of the porcine zona pellucida (ZP). In a continuing assessment of ZP3 as a candidate antigen for contraceptive vaccine development, female squirrel monkeys were immunized with 200 μg ZP3 using either Freund's adjuvant (FA) or muramyl dipeptide (MDP) and the effect of such immunization on ovarian histology examined. Two experimental and three control groups were immunized: Group 1 (n = 4), Z…
Biological Anthropology
New method for in vivo recording of myometrial activity in the squirrel monkey, Saimiri sciureus
Videolaparoscopy was used to visualize the reproductive tract contractility of the squirrel monkey, Saimiri sciureus . This technique gives information on the nature, direction of propagation, duration, and frequency of contractions. At the times of ovulation, and embryo entry to the uterus, contractile activity was observed in both the uterus and oviduct, with the latter being more frequent. The dominant direction of propagation was towards the …
In vitro fertilization analysis of squirrel monkey oocytes produced by various follicular induction regimens and the incidence of triploidy
An in vitro fertilization system utilizing squirrel monkeys was used to compare follicle‐stimulating hormone, clomiphene citrate and prostaglandin E 1 as follicular induction regimens, analyze culture medium characteristics, and examine the physiological phenomenon of polyspermy. Induction of follicular growth was poor with clomiphene citrate when compared to the control group and increased the incidence of atretic follicles at all levels tested.…
Presidential address
Incorporation of a GnRH agonist, leuprolide acetate, into regimens with exogenous gonadotropins to produce ovarian stimulation and ovulation in the nonpregnant squirrel monkey
This study was designed to measure the effects of variations in the length of pretreatment with a GnRH agonist, leuprolide acetate (LA), on subsequent follicular development and ovulation. The hypothesis was that the duration of LA suppression of pituitary function does not adversely affect ovarian response to standardized ovulation induction protocols in squirrel monkeys. The first phase determined the dose and duration of LA needed to achieve a…
Reflections on a century of primatology
Nonhuman Primate Models for Human Diseases
Biology (14 works) · Medicine (10 works) · Squirrel monkey (9 works) · Andrology (6 works) · Endocrinology (6 works) · Anatomy (5 works) · Ecology (5 works) · Hormone (5 works) · Ovulation (5 works) · Saimiri sciureus (5 works)