Ane Bærent Fisker
Biographic Data
| ID | 5194390 |
|---|---|
| NAME | Ane Bærent Fisker |
| GIVEN NAMES | Ane Bærent |
| FAMILY NAME | Fisker |
| SIGNATURE | FISKER A B |
| AFFILIATIONS | Statens Serum Institut |
| ORCID | 0000-0002-8521-0992 |
| VERIFIED | Yes |
| TOTAL WORKS | 17 |
| TOTAL CITATIONS | 5 |
| WORKS AS AUTHOR | 17 |
| WORKS AS EDITOR | 0 |
| FIRST PUBLICATION YEAR | 2013 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 1 |
Displacements in reported date of birth and differences in age at death in surveys of child mortality
Child mortality data in low- and middle-income countries are often derived from survey data prone to imprecision due to recall. Such imprecisions can affect the accuracy of date of birth (DOB) and age at death (AAD). Bandim Health Project runs two Health and Demographic Surveillance Systems (HDSSs) collecting prospective information on pregnancies, births, and deaths in Guinea-Bissau. In a survey, HDSS resident women were interviewed on their bir…
Gender disparities in death registration during the Covid-19 pandemic in an urban African setting
BACKGROUND In many low- and middle-income countries (LMICs), the completeness of death registration is lower among women, hampering accurate monitoring of health and mortality, gender equality, and rights. OBJECTIVE We quantify the gender gap in death registration and examine its determinants in Guinea-Bissau, a data-scarce West African context during 2020–2023, a period of potentially high mortality. METHODS We collected survey data from 477 urb…
Can earlier BCG-Japan and OPV vaccination reduce early infant mortality? A cluster-randomised trial in Guinea-Bissau
OBJECTIVE: To assess the effect of providing BCG and oral polio vaccine (OPV) at an early home visit after delivery. DESIGN: Cluster-randomised trial, randomising 92 geographically defined clusters 1:1 to intervention/control arms. SETTING: Bandim Health Project Health and Demographic Surveillance System, Guinea-Bissau. PARTICIPANTS: 2226 newborns enrolled between July 2016 and August 2019. INTERVENTIONS: In both arms, newborns received a home vi…
Effect of distributing locally produced cloth facemasks on Covid-19-like illness and all-cause mortality–a cluster-randomised controlled trial in urban Guinea-Bissau
Facemasks have been employed to mitigate the spread of SARS-CoV-2. The community effect of providing cloth facemasks on COVID-19 morbidity and mortality is unknown. In a cluster randomised trial in urban Bissau, Guinea-Bissau, clusters (geographical areas with an average of 19 houses), were randomised to an intervention or control arm using computer-generated random numbers. Between 20 July 2020 and 22 January 2021, trial participants (aged 10+ y…
Provider-mother interactions are associated with birth outcome misclassifications in household surveys
Background: Approximately 4.4 million children die peripartum annually, primarily in low- and middle-income countries. Accurate mortality tracking is essential to prioritising prevention efforts but is undermined by misclassification between stillbirths (SBs) and early neonatal deaths (ENNDs) in household surveys, which serve as key data sources. We explored and quantified associations between peripartum provider-mother interactions and misclassi…
Disregarding the restrictive vial-opening policy for BCG vaccine in Guinea-Bissau
OBJECTIVE: BCG vaccination is frequently delayed in low-income countries. Restrictive vial-opening policies, where a vial of BCG vaccine is not opened for few children, are a major reason for delay. During delays, children are unprotected against tuberculosis (TB) and deprived of non-specific effects of BCG. We assessed the potential effect and cost-effectiveness of disregarding the restrictive vial-opening policy, on TB and all-cause mortality, …
The mortality effects of disregarding the strategy to save doses of measles vaccine
INTRODUCTION: Measles vaccine (MV) may improve health beyond measles protection. To avoid wastage from multi-dose vials, children in Guinea-Bissau are only measles vaccinated when aged 9-11 months and when six or more children are present. We assessed health impacts of providing MV to all measles-unvaccinated children 9-35 months. METHODS: We cluster-randomised 182 village clusters under demographic surveillance in rural Guinea-Bissau to an 'MV-f…
Factors associated with birthweight and adverse pregnancy outcomes among children in rural Guinea-Bissau - a prospective observational study
This study provides the first birthweight data for home-born children in rural Guinea-Bissau, with a mean birthweight of 2.89 kg (SD 0.43) and a LBW prevalence of 17%. We found a tendency for higher risk of adverse pregnancy outcomes among BCG scar-negative women. Birthweight was similar in children of mothers with and without BCG scar
Complete and on-time routine childhood immunisation
Background: Completion of the full series of childhood vaccines on-time is crucial to ensuring greater protection against vaccine-preventable diseases. Aim: To examine determinants of complete and on-time vaccination and evaluate the relationship between vaccination patterns and severe morbidity outcomes. Subjects and methods: Vaccination information from infants in Nairobi Urban Health and Demographic Surveillance System was used to evaluate ful…
Biases in Survey Estimates of Neonatal Mortality
Neonatal deaths (occurring within 28 days of birth) account for close to one-half of all deaths among children under age 5 worldwide. In most low- and middle-income countries, data on neonatal deaths come primarily from household surveys. We conducted a validation study of survey data on neonatal mortality in Guinea-Bissau (West Africa). We used records from an urban health and demographic surveillance system (HDSS) that monitors child survival p…
“Every Newborn-INDEPTH” (EN-INDEPTH) study protocol for a randomised comparison of household survey modules for measuring stillbirths and neonatal deaths in five Health and Demographic Surveillance si…
BACKGROUND: may underestimate mortality rates particularly for stillbirths. METHODS: and FPH to measure pregnancy outcomes in a household survey in five selected INDEPTH Network sites in Africa and South Asia (Bandim in urban and rural Guinea-Bissau; Dabat in Ethiopia; IgangaMayuge in Uganda; Kintampo in Ghana; Matlab in Bangladesh). The survey will reach >68 000 pregnancies to assess if there is ≥15% difference in stillbirth rates. Additional qu…
Research protocol of two concurrent cluster-randomized trials
NCT03460002
Is early measles vaccination associated with stronger survival benefits than later measles vaccination
Early MV was associated with a large survival advantage. The current policy to increase vaccination age, when measles control improves, may not optimize the impact of MV on child survival
Cost-effectiveness of providing measles vaccination to all children in Guinea-Bissau
BACKGROUND: Measles vaccination is associated with major reductions in child mortality and morbidity. In Guinea-Bissau, to limit vaccine wastage, children are only measles-vaccinated if at least six children aged 9-11 months are present at a vaccination session. OBJECTIVE: To estimate the incremental cost-effectiveness of providing measles vaccine (MV) to all children regardless of age and number of children present. METHODS: We estimated MV cove…
Vaccination coverage and factors associated with adherence to the vaccination schedule in young children of a rural area in Burkina Faso
BACKGROUND: Vaccination is an important tool for reducing infectious disease morbidity and mortality. In the past, less than 80% of children 12-23 months of age were fully immunized in Burkina Faso. OBJECTIVES: To describe coverage and assess factors associated with adherence to the vaccination schedule in rural area Burkina Faso. METHODS: The study population was extracted from the Nouna Health and Demographic surveillance system cohort. Data fr…
BCG coverage and barriers to BCG vaccination in Guinea-Bissau
BCG coverage during the first months of life is low in Guinea-Bissau. Providing BCG at monthly vaccination visits removes the risk factors associated with delayed BCG vaccination
Determinants of vitamin a deficiency in children between 6 months and 2 years of age in Guinea-Bissau
Clinicaltrials.gov NCT00514891
Biases in Survey Estimates of Neonatal Mortality
Neonatal deaths (occurring within 28 days of birth) account for close to one-half of all deaths among children under age 5 worldwide. In most low- and middle-income countries, data on neonatal deaths come primarily from household surveys. We conducted a validation study of survey data on neonatal mortality in Guinea-Bissau (West Africa). We used records from an urban health and demographic surveillance system (HDSS) that monitors child survival p…
Determinants of vitamin a deficiency in children between 6 months and 2 years of age in Guinea-Bissau
Clinicaltrials.gov NCT00514891
BCG coverage and barriers to BCG vaccination in Guinea-Bissau
BCG coverage during the first months of life is low in Guinea-Bissau. Providing BCG at monthly vaccination visits removes the risk factors associated with delayed BCG vaccination
Cost-effectiveness of providing measles vaccination to all children in Guinea-Bissau
BACKGROUND: Measles vaccination is associated with major reductions in child mortality and morbidity. In Guinea-Bissau, to limit vaccine wastage, children are only measles-vaccinated if at least six children aged 9-11 months are present at a vaccination session. OBJECTIVE: To estimate the incremental cost-effectiveness of providing measles vaccine (MV) to all children regardless of age and number of children present. METHODS: We estimated MV cove…
Vaccination coverage and factors associated with adherence to the vaccination schedule in young children of a rural area in Burkina Faso
BACKGROUND: Vaccination is an important tool for reducing infectious disease morbidity and mortality. In the past, less than 80% of children 12-23 months of age were fully immunized in Burkina Faso. OBJECTIVES: To describe coverage and assess factors associated with adherence to the vaccination schedule in rural area Burkina Faso. METHODS: The study population was extracted from the Nouna Health and Demographic surveillance system cohort. Data fr…
Is early measles vaccination associated with stronger survival benefits than later measles vaccination
Early MV was associated with a large survival advantage. The current policy to increase vaccination age, when measles control improves, may not optimize the impact of MV on child survival
“Every Newborn-INDEPTH” (EN-INDEPTH) study protocol for a randomised comparison of household survey modules for measuring stillbirths and neonatal deaths in five Health and Demographic Surveillance si…
BACKGROUND: may underestimate mortality rates particularly for stillbirths. METHODS: and FPH to measure pregnancy outcomes in a household survey in five selected INDEPTH Network sites in Africa and South Asia (Bandim in urban and rural Guinea-Bissau; Dabat in Ethiopia; IgangaMayuge in Uganda; Kintampo in Ghana; Matlab in Bangladesh). The survey will reach >68 000 pregnancies to assess if there is ≥15% difference in stillbirth rates. Additional qu…
Research protocol of two concurrent cluster-randomized trials
NCT03460002
Complete and on-time routine childhood immunisation
Background: Completion of the full series of childhood vaccines on-time is crucial to ensuring greater protection against vaccine-preventable diseases. Aim: To examine determinants of complete and on-time vaccination and evaluate the relationship between vaccination patterns and severe morbidity outcomes. Subjects and methods: Vaccination information from infants in Nairobi Urban Health and Demographic Surveillance System was used to evaluate ful…
Biases in Survey Estimates of Neonatal Mortality
Neonatal deaths (occurring within 28 days of birth) account for close to one-half of all deaths among children under age 5 worldwide. In most low- and middle-income countries, data on neonatal deaths come primarily from household surveys. We conducted a validation study of survey data on neonatal mortality in Guinea-Bissau (West Africa). We used records from an urban health and demographic surveillance system (HDSS) that monitors child survival p…
Disregarding the restrictive vial-opening policy for BCG vaccine in Guinea-Bissau
OBJECTIVE: BCG vaccination is frequently delayed in low-income countries. Restrictive vial-opening policies, where a vial of BCG vaccine is not opened for few children, are a major reason for delay. During delays, children are unprotected against tuberculosis (TB) and deprived of non-specific effects of BCG. We assessed the potential effect and cost-effectiveness of disregarding the restrictive vial-opening policy, on TB and all-cause mortality, …
The mortality effects of disregarding the strategy to save doses of measles vaccine
INTRODUCTION: Measles vaccine (MV) may improve health beyond measles protection. To avoid wastage from multi-dose vials, children in Guinea-Bissau are only measles vaccinated when aged 9-11 months and when six or more children are present. We assessed health impacts of providing MV to all measles-unvaccinated children 9-35 months. METHODS: We cluster-randomised 182 village clusters under demographic surveillance in rural Guinea-Bissau to an 'MV-f…
Factors associated with birthweight and adverse pregnancy outcomes among children in rural Guinea-Bissau - a prospective observational study
This study provides the first birthweight data for home-born children in rural Guinea-Bissau, with a mean birthweight of 2.89 kg (SD 0.43) and a LBW prevalence of 17%. We found a tendency for higher risk of adverse pregnancy outcomes among BCG scar-negative women. Birthweight was similar in children of mothers with and without BCG scar
Provider-mother interactions are associated with birth outcome misclassifications in household surveys
Background: Approximately 4.4 million children die peripartum annually, primarily in low- and middle-income countries. Accurate mortality tracking is essential to prioritising prevention efforts but is undermined by misclassification between stillbirths (SBs) and early neonatal deaths (ENNDs) in household surveys, which serve as key data sources. We explored and quantified associations between peripartum provider-mother interactions and misclassi…
Can earlier BCG-Japan and OPV vaccination reduce early infant mortality? A cluster-randomised trial in Guinea-Bissau
OBJECTIVE: To assess the effect of providing BCG and oral polio vaccine (OPV) at an early home visit after delivery. DESIGN: Cluster-randomised trial, randomising 92 geographically defined clusters 1:1 to intervention/control arms. SETTING: Bandim Health Project Health and Demographic Surveillance System, Guinea-Bissau. PARTICIPANTS: 2226 newborns enrolled between July 2016 and August 2019. INTERVENTIONS: In both arms, newborns received a home vi…
Effect of distributing locally produced cloth facemasks on Covid-19-like illness and all-cause mortality–a cluster-randomised controlled trial in urban Guinea-Bissau
Facemasks have been employed to mitigate the spread of SARS-CoV-2. The community effect of providing cloth facemasks on COVID-19 morbidity and mortality is unknown. In a cluster randomised trial in urban Bissau, Guinea-Bissau, clusters (geographical areas with an average of 19 houses), were randomised to an intervention or control arm using computer-generated random numbers. Between 20 July 2020 and 22 January 2021, trial participants (aged 10+ y…
Displacements in reported date of birth and differences in age at death in surveys of child mortality
Child mortality data in low- and middle-income countries are often derived from survey data prone to imprecision due to recall. Such imprecisions can affect the accuracy of date of birth (DOB) and age at death (AAD). Bandim Health Project runs two Health and Demographic Surveillance Systems (HDSSs) collecting prospective information on pregnancies, births, and deaths in Guinea-Bissau. In a survey, HDSS resident women were interviewed on their bir…
Gender disparities in death registration during the Covid-19 pandemic in an urban African setting
BACKGROUND In many low- and middle-income countries (LMICs), the completeness of death registration is lower among women, hampering accurate monitoring of health and mortality, gender equality, and rights. OBJECTIVE We quantify the gender gap in death registration and examine its determinants in Guinea-Bissau, a data-scarce West African context during 2020–2023, a period of potentially high mortality. METHODS We collected survey data from 477 urb…
Medicine (16 works) · Environmental health (13 works) · Demography (10 works) · Immune responses and vaccinations (10 works) · New guinea (9 works) · Vaccine Coverage and Hesitancy (9 works) · Pediatrics (8 works) · Internal Medicine (7 works) · Vaccination (7 works) · Demography (6 works)