Susanne Walitza
Datos Biográficos
| ID | 5221520 |
|---|---|
| NOMBRE | Susanne Walitza |
| NOMBRES | Susanne |
| APELLIDO | Walitza |
| FIRMA | WALITZA S |
| AFILIACIONES | University of Zurich |
| ORCID | 0000-0002-8161-8683 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 24 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 24 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2017 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2025 |
| ÍNDICE H | 0 |
Gaze behavior, facial emotion processing, and neural underpinnings
BACKGROUND: Facial emotion processing deficits and atypical eye gaze are often described in individuals with autism spectrum disorder (ASD) and those with conduct disorder (CD) and high callous unemotional (CU) traits. Yet, the underlying neural mechanisms of these deficits are still unclear. The aim of this study was to investigate if eye gaze can partially account for the differences in brain activation in youth with ASD, with CD, and typically…
The Body as a Battleground
Perceived experiences of violence, trauma, body dissatisfaction, and body shaming emerge as interconnected factors contributing to suicide attempts among adolescents. There is a critical need to improve the understanding and prediction of suicide attempts in this vulnerable population. In this study, a primarily qualitative design was employed, supported by descriptive quantitative elements, such as code frequencies and word clouds, to explore in…
Effect of Medical Interventions on Body Satisfaction in Gender-Dysphoric Adolescents
Body dissatisfaction contributes to distress in gender dysphoria, but longitudinal evidence on factors alleviating this discomfort is limited. This naturalistic study examined the effect of gender-affirming hormone therapy (GAHT) alone and in combination with gender-affirming surgery (GAHT + GAS) on body satisfaction. Eighty-two adolescents (mean age, 15.77 ± 1.37) referred to a specialist clinic were examined at two time points and classified in…
Weakened effective connectivity between salience network and default mode network during resting state in adolescent depression
Adolescent major depressive disorder (MDD) is associated with altered resting-state connectivity between the default mode network (DMN) and the salience network (SN), which are involved in self-referential processing and detecting and filtering salient stimuli, respectively. Using spectral dynamical causal modelling, we investigated the effective connectivity and input sensitivity between key nodes of these networks in 30 adolescents with MDD and…
Limited usefulness of neurocognitive functioning indices as predictive markers for treatment response to methylphenidate or neurofeedback@home in children and adolescents with ADHD
Current findings indicate a potential value of self-report (BRIEF global score) and some objectively measured neurocognitive indices (CPT commission errors and hit reaction time variability) as treatment markers (of change) for MPH. However, we found a rather limited prognostic value with regard to predicting treatment response not (yet) allowing recommendation for clinical use. Baseline symptom severity was revealed as the most relevant predicto…
Mismatch negativity generation in subjects at risk for psychosis
MMN activity differed significantly between subjects presenting only basic symptoms and subjects which additionally meet UHR criteria. The largest differences between groups as well as between individuals with and without transition were observed at the frontal source. The present results suggest that source analysis is more sensitive than surface electrodes in psychosis risk prediction by MMN
Sleep spindles across youth affected by schizophrenia or anti-N-methyl-D-aspartate-receptor encephalitis
Patients with COS demonstrated more pronounced impairments of sleep spindles compared to patients with EOS and NMDARE. In this sample, there is no strong evidence that changes in NMDAR activity are related to spindle deficits
The Impact of the Covid-19 Pandemic on Young Adults’ Mental Health in Switzerland
Most of the studies that examine the effect of the COVID-19 pandemic on mental health have been restricted to pandemic mental health data alone. The aim of the current study was to estimate the pandemic's effect on young Swiss adults' mental health by comparing pandemic to pre-pandemic mental health. Longitudinal data of 1175 young Swiss adults who participated in the S-YESMH study in 2018 and were followed-up in 2020 and 2021 were analyzed. The …
Advances in problematic usage of the internet research – A narrative review by experts from the European network for problematic usage of the internet
Problematic use of digital media in children and adolescents with a diagnosis of attention-deficit/hyperactivity disorder compared to controls. A meta-analysis
Personalized at‐home neurofeedback compared to long‐acting methylphenidate in children with ADHD
BACKGROUND: Neurofeedback is considered a promising intervention for the treatment of attention-deficit hyperactivity disorder (ADHD). NEWROFEED is a prospective, multicentre, randomized (3:2), reference drug-controlled trial in children with ADHD aged between 7 and 13 years. The main objective of NEWROFEED was to demonstrate the noninferiority of personalized at-home neurofeedback (NF) training versus methylphenidate in the treatment of children…
Family Relationships in Selective Mutism—A Comparison Group Study of Children and Adolescents
Selective mutism (SM) mostly develops early in childhood and this has led to interest into whether there could be differences in relationships in families with SM compared to a control group without SM. Currently, there are merely few empirical studies examining family relationships in SM. A sample of 28 children and adolescents with SM was compared to 33 controls without SM. The groups were investigated using self-report questionnaires (Selectiv…
Responsivity of the Striatal Dopamine System to Methylphenidate—A Within-Subject I-123-β-CIT-SPECT Study in Male Children and Adolescents With Attention-Deficit/Hyperactivity Disorder
Our findings corroborate previous reports from mainly adult samples that MPH changes striatal DAT BP availability and suggest higher off-MPH DAT BP, likely reflecting low baseline DA levels, as a marker of symptom severity
The Impact of the Covid-19 Pandemic on Mental Health Care of Children and Adolescents in Switzerland
For the first pandemic year, youth mental health professionals reported a large increase in the treatment demand and waiting time and a worrisome overload of treatment services
Schüchterne und sozial ängstliche Kinder in der Schule
Schüchterne Kinder und Jugendliche werden in der Schule häufig übersehen. Sie stören den Unterricht nicht, sind im Umgang "angenehm". Kinder, die unter Ängsten leiden, sind in fast jeder Klasse zu finden. Der Band gibt einen Überblick über wichtige Aspekte von Schüchternheit im Kontext Schule: Internationale Expertinnen und Experten schreiben über Grundlagen von Schüchternheit und schulspezifische Auswirkungen. Erfolgreiche therapeutische Ansätze…
The World Federation of ADHD International Consensus Statement
BACKGROUND: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. METHODS: We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For net…
Analysis of structural brain asymmetries in attention‐deficit/hyperactivity disorder in 39 datasets
OBJECTIVE: Some studies have suggested alterations of structural brain asymmetry in attention-deficit/hyperactivity disorder (ADHD), but findings have been contradictory and based on small samples. Here, we performed the largest ever analysis of brain left-right asymmetry in ADHD, using 39 datasets of the ENIGMA consortium. METHODS: We analyzed asymmetry of subcortical and cerebral cortical structures in up to 1,933 people with ADHD and 1,829 una…
Stress and Mental Health among Children/Adolescents, Their Parents, and Young Adults during the First Covid-19 Lockdown in Switzerland
The present study aimed to assess various stressful situations and the psychological impact of the first COVID-19 pandemic lockdown among youths in Switzerland. We included samples of 1627 young adults aged 19-24 from the Swiss Youth Epidemiological Study on Mental Health and 1146 children and adolescents aged 12-17 years and their parents. We assessed symptoms of various mental health problems, internet use, and perceived stress during the first…
Preventing problematic internet use during the Covid-19 pandemic
As a response to the COVID-19 pandemic, many governments have introduced steps such as spatial distancing and "staying at home" to curb its spread and impact. The fear resulting from the disease, the 'lockdown' situation, high levels of uncertainty regarding the future, and financial insecurity raise the level of stress, anxiety, and depression experienced by people all around the world. Psychoactive substances and other reinforcing behaviors (e.…
DSM-5 Attenuated Psychosis Syndrome in Adolescents Hospitalized With Non-psychotic Psychiatric Disorders
Introduction: Although attenuated psychotic symptoms often occur for the first time during adolescence, studies focusing on adolescents are scarce. Attenuated psychotic symptoms form the criteria to identify individuals at increased clinical risk of developing psychosis. The study of individuals with these symptoms has led to the release of the DSM-5 diagnosis of Attenuated Psychosis Syndrome (APS) as a condition for further research. We aimed to…
Early Somatosensory Processing Over Time in Individuals at Risk to Develop Psychosis
Objective: Somatosensory evoked potentials (SEPs) enable the investigation of thalamocortical and early cortical processing. Previous studies reported alterations of SEPs in patients with schizophrenia as well as in individuals in the prodromal stage. Moreover, cannabis use as an environmental risk factor for the development of schizophrenia has been demonstrated to influence SEP parameters in individuals at risk to develop psychosis. The aim of …
Omega-3 Fatty Acids as a Treatment for Pediatric Depression. A Phase III, 36 Weeks, Multi-Center, Double-Blind, Placebo-Controlled Randomized Superiority Study
Background: Depressive disorders in childhood and adolescence are a major health problem and often follow a chronic course with severe consequences in later life. Depressive disorders cause the highest burden of disease in this age group across all medical conditions. Treatment adherence is usually very poor, and the use of antidepressant drugs is heavily debated, as suicidal ideations may increase, in particular in the early phase of treatment. …
Evaluation of the Combined Treatment Approach “Robin” (Standardized Manual and Smartphone App) for Adolescents at Clinical High Risk for Psychosis
Introduction: The prevention of schizophrenia and other psychotic disorders has led researchers to focus on early identification of individuals at clinical high risk (CHR) for psychosis and to treat the at-risk symptoms in the pre-psychotic period. Although at-risk symptoms such as attenuated hallucinations or delusions are common in adolescents and associated with a marked reduction in global functioning, the evidence base of effective intervent…
Prediction Analysis for Transition to Schizophrenia in Individuals at Clinical High Risk for Psychosis
Schizophrenia is characterized by positive and negative symptoms and cognitive dysfunction. The glutamate hypothesis of schizophrenia has been hypothesized to explain the negative symptoms and cognitive deficits better than the dopamine hypothesis alone. Therefore, we aimed to evaluate whether glutamatergic variants such as d-amino acid oxidase ( DAO ), DAO activator ( DAOA )/ G72 , and neuregulin 1 ( NRG1 ) single-nucleotide polymorphisms (SNPs)…
Sin obras prominentes en esta página.
Prediction Analysis for Transition to Schizophrenia in Individuals at Clinical High Risk for Psychosis
Schizophrenia is characterized by positive and negative symptoms and cognitive dysfunction. The glutamate hypothesis of schizophrenia has been hypothesized to explain the negative symptoms and cognitive deficits better than the dopamine hypothesis alone. Therefore, we aimed to evaluate whether glutamatergic variants such as d-amino acid oxidase ( DAO ), DAO activator ( DAOA )/ G72 , and neuregulin 1 ( NRG1 ) single-nucleotide polymorphisms (SNPs)…
Early Somatosensory Processing Over Time in Individuals at Risk to Develop Psychosis
Objective: Somatosensory evoked potentials (SEPs) enable the investigation of thalamocortical and early cortical processing. Previous studies reported alterations of SEPs in patients with schizophrenia as well as in individuals in the prodromal stage. Moreover, cannabis use as an environmental risk factor for the development of schizophrenia has been demonstrated to influence SEP parameters in individuals at risk to develop psychosis. The aim of …
Omega-3 Fatty Acids as a Treatment for Pediatric Depression. A Phase III, 36 Weeks, Multi-Center, Double-Blind, Placebo-Controlled Randomized Superiority Study
Background: Depressive disorders in childhood and adolescence are a major health problem and often follow a chronic course with severe consequences in later life. Depressive disorders cause the highest burden of disease in this age group across all medical conditions. Treatment adherence is usually very poor, and the use of antidepressant drugs is heavily debated, as suicidal ideations may increase, in particular in the early phase of treatment. …
Evaluation of the Combined Treatment Approach “Robin” (Standardized Manual and Smartphone App) for Adolescents at Clinical High Risk for Psychosis
Introduction: The prevention of schizophrenia and other psychotic disorders has led researchers to focus on early identification of individuals at clinical high risk (CHR) for psychosis and to treat the at-risk symptoms in the pre-psychotic period. Although at-risk symptoms such as attenuated hallucinations or delusions are common in adolescents and associated with a marked reduction in global functioning, the evidence base of effective intervent…
Preventing problematic internet use during the Covid-19 pandemic
As a response to the COVID-19 pandemic, many governments have introduced steps such as spatial distancing and "staying at home" to curb its spread and impact. The fear resulting from the disease, the 'lockdown' situation, high levels of uncertainty regarding the future, and financial insecurity raise the level of stress, anxiety, and depression experienced by people all around the world. Psychoactive substances and other reinforcing behaviors (e.…
DSM-5 Attenuated Psychosis Syndrome in Adolescents Hospitalized With Non-psychotic Psychiatric Disorders
Introduction: Although attenuated psychotic symptoms often occur for the first time during adolescence, studies focusing on adolescents are scarce. Attenuated psychotic symptoms form the criteria to identify individuals at increased clinical risk of developing psychosis. The study of individuals with these symptoms has led to the release of the DSM-5 diagnosis of Attenuated Psychosis Syndrome (APS) as a condition for further research. We aimed to…
Schüchterne und sozial ängstliche Kinder in der Schule
Schüchterne Kinder und Jugendliche werden in der Schule häufig übersehen. Sie stören den Unterricht nicht, sind im Umgang "angenehm". Kinder, die unter Ängsten leiden, sind in fast jeder Klasse zu finden. Der Band gibt einen Überblick über wichtige Aspekte von Schüchternheit im Kontext Schule: Internationale Expertinnen und Experten schreiben über Grundlagen von Schüchternheit und schulspezifische Auswirkungen. Erfolgreiche therapeutische Ansätze…
The World Federation of ADHD International Consensus Statement
BACKGROUND: Misconceptions about ADHD stigmatize affected people, reduce credibility of providers, and prevent/delay treatment. To challenge misconceptions, we curated findings with strong evidence base. METHODS: We reviewed studies with more than 2000 participants or meta-analyses from five or more studies or 2000 or more participants. We excluded meta-analyses that did not assess publication bias, except for meta-analyses of prevalence. For net…
Analysis of structural brain asymmetries in attention‐deficit/hyperactivity disorder in 39 datasets
OBJECTIVE: Some studies have suggested alterations of structural brain asymmetry in attention-deficit/hyperactivity disorder (ADHD), but findings have been contradictory and based on small samples. Here, we performed the largest ever analysis of brain left-right asymmetry in ADHD, using 39 datasets of the ENIGMA consortium. METHODS: We analyzed asymmetry of subcortical and cerebral cortical structures in up to 1,933 people with ADHD and 1,829 una…
Stress and Mental Health among Children/Adolescents, Their Parents, and Young Adults during the First Covid-19 Lockdown in Switzerland
The present study aimed to assess various stressful situations and the psychological impact of the first COVID-19 pandemic lockdown among youths in Switzerland. We included samples of 1627 young adults aged 19-24 from the Swiss Youth Epidemiological Study on Mental Health and 1146 children and adolescents aged 12-17 years and their parents. We assessed symptoms of various mental health problems, internet use, and perceived stress during the first…
Advances in problematic usage of the internet research – A narrative review by experts from the European network for problematic usage of the internet
Problematic use of digital media in children and adolescents with a diagnosis of attention-deficit/hyperactivity disorder compared to controls. A meta-analysis
Personalized at‐home neurofeedback compared to long‐acting methylphenidate in children with ADHD
BACKGROUND: Neurofeedback is considered a promising intervention for the treatment of attention-deficit hyperactivity disorder (ADHD). NEWROFEED is a prospective, multicentre, randomized (3:2), reference drug-controlled trial in children with ADHD aged between 7 and 13 years. The main objective of NEWROFEED was to demonstrate the noninferiority of personalized at-home neurofeedback (NF) training versus methylphenidate in the treatment of children…
Family Relationships in Selective Mutism—A Comparison Group Study of Children and Adolescents
Selective mutism (SM) mostly develops early in childhood and this has led to interest into whether there could be differences in relationships in families with SM compared to a control group without SM. Currently, there are merely few empirical studies examining family relationships in SM. A sample of 28 children and adolescents with SM was compared to 33 controls without SM. The groups were investigated using self-report questionnaires (Selectiv…
Responsivity of the Striatal Dopamine System to Methylphenidate—A Within-Subject I-123-β-CIT-SPECT Study in Male Children and Adolescents With Attention-Deficit/Hyperactivity Disorder
Our findings corroborate previous reports from mainly adult samples that MPH changes striatal DAT BP availability and suggest higher off-MPH DAT BP, likely reflecting low baseline DA levels, as a marker of symptom severity
The Impact of the Covid-19 Pandemic on Mental Health Care of Children and Adolescents in Switzerland
For the first pandemic year, youth mental health professionals reported a large increase in the treatment demand and waiting time and a worrisome overload of treatment services
Mismatch negativity generation in subjects at risk for psychosis
MMN activity differed significantly between subjects presenting only basic symptoms and subjects which additionally meet UHR criteria. The largest differences between groups as well as between individuals with and without transition were observed at the frontal source. The present results suggest that source analysis is more sensitive than surface electrodes in psychosis risk prediction by MMN
Sleep spindles across youth affected by schizophrenia or anti-N-methyl-D-aspartate-receptor encephalitis
Patients with COS demonstrated more pronounced impairments of sleep spindles compared to patients with EOS and NMDARE. In this sample, there is no strong evidence that changes in NMDAR activity are related to spindle deficits
The Impact of the Covid-19 Pandemic on Young Adults’ Mental Health in Switzerland
Most of the studies that examine the effect of the COVID-19 pandemic on mental health have been restricted to pandemic mental health data alone. The aim of the current study was to estimate the pandemic's effect on young Swiss adults' mental health by comparing pandemic to pre-pandemic mental health. Longitudinal data of 1175 young Swiss adults who participated in the S-YESMH study in 2018 and were followed-up in 2020 and 2021 were analyzed. The …
Weakened effective connectivity between salience network and default mode network during resting state in adolescent depression
Adolescent major depressive disorder (MDD) is associated with altered resting-state connectivity between the default mode network (DMN) and the salience network (SN), which are involved in self-referential processing and detecting and filtering salient stimuli, respectively. Using spectral dynamical causal modelling, we investigated the effective connectivity and input sensitivity between key nodes of these networks in 30 adolescents with MDD and…
Limited usefulness of neurocognitive functioning indices as predictive markers for treatment response to methylphenidate or neurofeedback@home in children and adolescents with ADHD
Current findings indicate a potential value of self-report (BRIEF global score) and some objectively measured neurocognitive indices (CPT commission errors and hit reaction time variability) as treatment markers (of change) for MPH. However, we found a rather limited prognostic value with regard to predicting treatment response not (yet) allowing recommendation for clinical use. Baseline symptom severity was revealed as the most relevant predicto…
Gaze behavior, facial emotion processing, and neural underpinnings
BACKGROUND: Facial emotion processing deficits and atypical eye gaze are often described in individuals with autism spectrum disorder (ASD) and those with conduct disorder (CD) and high callous unemotional (CU) traits. Yet, the underlying neural mechanisms of these deficits are still unclear. The aim of this study was to investigate if eye gaze can partially account for the differences in brain activation in youth with ASD, with CD, and typically…
The Body as a Battleground
Perceived experiences of violence, trauma, body dissatisfaction, and body shaming emerge as interconnected factors contributing to suicide attempts among adolescents. There is a critical need to improve the understanding and prediction of suicide attempts in this vulnerable population. In this study, a primarily qualitative design was employed, supported by descriptive quantitative elements, such as code frequencies and word clouds, to explore in…
Effect of Medical Interventions on Body Satisfaction in Gender-Dysphoric Adolescents
Body dissatisfaction contributes to distress in gender dysphoria, but longitudinal evidence on factors alleviating this discomfort is limited. This naturalistic study examined the effect of gender-affirming hormone therapy (GAHT) alone and in combination with gender-affirming surgery (GAHT + GAS) on body satisfaction. Eighty-two adolescents (mean age, 15.77 ± 1.37) referred to a specialist clinic were examined at two time points and classified in…
Psychology (20 obras) · Psychiatry (18 obras) · Medicine (16 obras) · Clinical Psychology (11 obras) · Clinical Psychology (9 obras) · Child and Adolescent Psychosocial and Emotional Development (7 obras) · Internal Medicine (7 obras) · Neuroscience (6 obras) · Psychosis (6 obras) · Anxiety (5 obras)