Charles Weijer
Biographic Data
| ID | 5396017 |
|---|---|
| NAME | Charles Weijer |
| GIVEN NAMES | Charles |
| FAMILY NAME | Weijer |
| SIGNATURE | WEIJER C |
| AFFILIATIONS | Western University |
| ORCID | 0000-0002-5510-1074 |
| VERIFIED | Yes |
| TOTAL WORKS | 26 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 26 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1992 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
The ethical permissibility of financial incentives
Randomized controlled trials are central to progress in medicine, but trialists commonly struggle to recruit the required number of participants. Offering financial incentives is one proposed solution, but financial incentives may be problematic when they become irresistible and, thus, undermine the autonomy of potential participants. While some have dismissed this worry about undue inducement and argued that we should be paying participants more…
Navigating the consent river
The robust design and conduct of pragmatic cluster randomised trials may be in tension with the ethical requirement to obtain written informed consent from prospective research participants. In our experience, researchers tend to focus on whether a waiver of consent is appropriate for their studies. However, pragmatic cluster randomised trials raise other important questions that have direct implications for determining when an alteration or waiv…
Covid-19 human challenge trials and randomized controlled trials
The COVID-19 pandemic touched off an unprecedented search for vaccines and treatments. Without question, the development of vaccines to prevent COVID-19 was an enormous scientific accomplishment. Further, the RECOVERY and Solidarity trials identified effective treatments for COVID-19. But all was not success. The urgent need for COVID-19 prevention and treatment fueled an embrace of risks—to research participants and to the reliability of the sci…
Ethics of non-therapeutic research on imminently dying patients in the intensive care unit
Non-therapeutic research with imminently dying patients in intensive care presents complex ethical issues. The vulnerabilities of the imminently dying, together with societal disquiet around death and dying, contribute to an intuition that such research is beyond the legitimate scope of scientific inquiry. Yet excluding imminently dying patients from research hinders the advancement of medical science to the detriment of future patients. Building…
Informed consent in pragmatic trials
OBJECTIVES: To describe reporting of informed consent in pragmatic trials, justifications for waivers of consent and reporting of alternative approaches to standard written consent. To identify factors associated with (1) not reporting and (2) not obtaining consent. METHODS: Survey of primary trial reports, published 2014-2019, identified using an electronic search filter for pragmatic trials implemented in MEDLINE, and registered in ClinicalTria…
Family experiences with non-therapeutic research on dying patients in the intensive care unit
Experiences of substitute decision-makers with requests for consent to non-therapeutic research participation during the dying process, including to what degree such requests are perceived as burdensome, have not been well described. In this study, we explored the lived experiences of family members who consented to non-therapeutic research participation on behalf of an imminently dying patient. We interviewed 33 family members involved in surrog…
Research bystanders, justice, and the state
Research participants are afforded protections to ensure their rights and welfare are not unduly jeopardized by research activities. Yet people who do not meet the criteria for research participant status may likewise be impacted by research activities, and ethicists argue that protections should be afforded these “research bystanders.” The standard rationale for extending protections to research bystanders contends that they are sufficiently lik…
Towards the assessment of quality of life in patients with disorders of consciousness
Cluster Randomized Trials, Ethical Implications of
Heads or Tails
Case Upon inspecting his schedule for the day, psychiatrist David Kimball was surprised to learn that his first patient of the morning was Geoffrey Allen. Geoff had been in for an appointment less than 2 weeks ago to discuss his response to a monoamine oxidase inhibitor (MAOI) as treatment for chronic depression. At the time, it seemed as though the medication was working, a relief for both Geoff and Dr. Kimball after several years of searching f…
Informing Study Participants of Research Results
Trial by Error
The Ethics Wars Disputes over International Research
The effort to revise the Declaration of Helsinki and the CIOMS Guidelines has sparked a sometimes vitriolic debate centering on the use of placebo controls
Moral Solutions in Assessing Research Risk
Thinking Clearly about Research Risk
ethics as exposure of muddled and wrong-headed concepts, to clear the way for a healthy growth of ideas.l In his twenty-year career in bioethics, he not only cleared the way but also filled the gap in a wide variety of areas in bioethics, including informed consent, substitute decision making, competency, obligations of health professionals, research ethics, and Judaism and bioethics.2 Perhaps best known among these many contributions is Freedman…
Structuring the Review of Human Genetics Protocols Part-III
Kathleen Cranley Glass, Charles Weijer, Denis Cournoyer, Trudo Lemmens, Reberta M. Palmour, Stanley H. Shapiro, Benjamin Freedman, Structuring the Review of Human Genetics Protocols Part-III: Gene Therapy Studies, IRB: Ethics & Human Research, Vol. 21, No. 2 (Mar. - Apr., 1999), pp. 1-9
The IRB's Role in Assessing the Generalizability of Non-NIH-Funded Clinical Trials
Monitoring Informed Consent in an Oncology Study Posing Serious Risk to Subjects
Myrian Skrutkowski, Charles Weijer, Stan Shapiro, Abraham Fuks, Adrian Langleben, Benjamin Freedman, Monitoring Informed Consent in an Oncology Study Posing Serious Risk to Subjects, IRB: Ethics & Human Research, Vol. 20, No. 6 (Nov. - Dec., 1998), pp. 1-6
Structuring the Review of Human Genetics Protocols Part II
Kathleen Cranley Glass, Charles Weijer, Trudo Lemmens, Roberta M. Palmour, Stanley H. Shapiro, Structuring the Review of Human Genetics Protocols Part II: Diagnostic and Screening Studies, IRB: Ethics & Human Research, Vol. 19, No. 3/4 (May - Aug., 1997), pp. 1-11+13
Notes on Recent Publications
Structuring the Review of Human Genetics Protocols
Kathleen Cranley Glass, Charles Weijer, Roberta M. Palmour, Stanley H. Shapiro, Trudo M. Lemmens, Karen Lebacqz, Structuring the Review of Human Genetics Protocols: Gene Localization and Identification Studies, IRB: Ethics & Human Research, Vol. 18, No. 4 (Jul. - Aug., 1996), pp. 1-9
Notes on Recent Publications
Momento mori
Notes on Recent Publications
In Loco Parentis Minimal Risk as an Ethical Threshold for Research upon Children
Benjamin Freedman, Abraham Fuks, Charles Weijer, In Loco Parentis Minimal Risk as an Ethical Threshold for Research upon Children, The Hastings Center Report, Vol. 23, No. 2 (Mar. - Apr., 1993), pp. 13-19
No prominent works on this page.
Demarcating Research and Treatment Interventions
In Loco Parentis Minimal Risk as an Ethical Threshold for Research upon Children
Benjamin Freedman, Abraham Fuks, Charles Weijer, In Loco Parentis Minimal Risk as an Ethical Threshold for Research upon Children, The Hastings Center Report, Vol. 23, No. 2 (Mar. - Apr., 1993), pp. 13-19
Momento mori
Notes on Recent Publications
Notes on Recent Publications
Notes on Recent Publications
Structuring the Review of Human Genetics Protocols
Kathleen Cranley Glass, Charles Weijer, Roberta M. Palmour, Stanley H. Shapiro, Trudo M. Lemmens, Karen Lebacqz, Structuring the Review of Human Genetics Protocols: Gene Localization and Identification Studies, IRB: Ethics & Human Research, Vol. 18, No. 4 (Jul. - Aug., 1996), pp. 1-9
Structuring the Review of Human Genetics Protocols Part II
Kathleen Cranley Glass, Charles Weijer, Trudo Lemmens, Roberta M. Palmour, Stanley H. Shapiro, Structuring the Review of Human Genetics Protocols Part II: Diagnostic and Screening Studies, IRB: Ethics & Human Research, Vol. 19, No. 3/4 (May - Aug., 1997), pp. 1-11+13
The IRB's Role in Assessing the Generalizability of Non-NIH-Funded Clinical Trials
Monitoring Informed Consent in an Oncology Study Posing Serious Risk to Subjects
Myrian Skrutkowski, Charles Weijer, Stan Shapiro, Abraham Fuks, Adrian Langleben, Benjamin Freedman, Monitoring Informed Consent in an Oncology Study Posing Serious Risk to Subjects, IRB: Ethics & Human Research, Vol. 20, No. 6 (Nov. - Dec., 1998), pp. 1-6
Thinking Clearly about Research Risk
ethics as exposure of muddled and wrong-headed concepts, to clear the way for a healthy growth of ideas.l In his twenty-year career in bioethics, he not only cleared the way but also filled the gap in a wide variety of areas in bioethics, including informed consent, substitute decision making, competency, obligations of health professionals, research ethics, and Judaism and bioethics.2 Perhaps best known among these many contributions is Freedman…
Structuring the Review of Human Genetics Protocols Part-III
Kathleen Cranley Glass, Charles Weijer, Denis Cournoyer, Trudo Lemmens, Reberta M. Palmour, Stanley H. Shapiro, Benjamin Freedman, Structuring the Review of Human Genetics Protocols Part-III: Gene Therapy Studies, IRB: Ethics & Human Research, Vol. 21, No. 2 (Mar. - Apr., 1999), pp. 1-9
Moral Solutions in Assessing Research Risk
Trial by Error
The Ethics Wars Disputes over International Research
The effort to revise the Declaration of Helsinki and the CIOMS Guidelines has sparked a sometimes vitriolic debate centering on the use of placebo controls
Informing Study Participants of Research Results
Heads or Tails
Case Upon inspecting his schedule for the day, psychiatrist David Kimball was surprised to learn that his first patient of the morning was Geoffrey Allen. Geoff had been in for an appointment less than 2 weeks ago to discuss his response to a monoamine oxidase inhibitor (MAOI) as treatment for chronic depression. At the time, it seemed as though the medication was working, a relief for both Geoff and Dr. Kimball after several years of searching f…
Cluster Randomized Trials, Ethical Implications of
Towards the assessment of quality of life in patients with disorders of consciousness
Family experiences with non-therapeutic research on dying patients in the intensive care unit
Experiences of substitute decision-makers with requests for consent to non-therapeutic research participation during the dying process, including to what degree such requests are perceived as burdensome, have not been well described. In this study, we explored the lived experiences of family members who consented to non-therapeutic research participation on behalf of an imminently dying patient. We interviewed 33 family members involved in surrog…
Research bystanders, justice, and the state
Research participants are afforded protections to ensure their rights and welfare are not unduly jeopardized by research activities. Yet people who do not meet the criteria for research participant status may likewise be impacted by research activities, and ethicists argue that protections should be afforded these “research bystanders.” The standard rationale for extending protections to research bystanders contends that they are sufficiently lik…
Ethics of non-therapeutic research on imminently dying patients in the intensive care unit
Non-therapeutic research with imminently dying patients in intensive care presents complex ethical issues. The vulnerabilities of the imminently dying, together with societal disquiet around death and dying, contribute to an intuition that such research is beyond the legitimate scope of scientific inquiry. Yet excluding imminently dying patients from research hinders the advancement of medical science to the detriment of future patients. Building…
Informed consent in pragmatic trials
OBJECTIVES: To describe reporting of informed consent in pragmatic trials, justifications for waivers of consent and reporting of alternative approaches to standard written consent. To identify factors associated with (1) not reporting and (2) not obtaining consent. METHODS: Survey of primary trial reports, published 2014-2019, identified using an electronic search filter for pragmatic trials implemented in MEDLINE, and registered in ClinicalTria…
Covid-19 human challenge trials and randomized controlled trials
The COVID-19 pandemic touched off an unprecedented search for vaccines and treatments. Without question, the development of vaccines to prevent COVID-19 was an enormous scientific accomplishment. Further, the RECOVERY and Solidarity trials identified effective treatments for COVID-19. But all was not success. The urgent need for COVID-19 prevention and treatment fueled an embrace of risks—to research participants and to the reliability of the sci…
Navigating the consent river
The robust design and conduct of pragmatic cluster randomised trials may be in tension with the ethical requirement to obtain written informed consent from prospective research participants. In our experience, researchers tend to focus on whether a waiver of consent is appropriate for their studies. However, pragmatic cluster randomised trials raise other important questions that have direct implications for determining when an alteration or waiv…
Psychology (20 works) · Ethics in Clinical Research (14 works) · Medicine (14 works) · Computer Science (9 works) · Alternative medicine (8 works) · Biomedical Ethics and Regulation (8 works) · Engineering (8 works) · Engineering ethics (8 works) · Law (8 works) · Political science (8 works)