Sheila Isanaka

Dados Biográficos

ID5458905
NOMESheila Isanaka
PRENOMESSheila
SOBRENOMEIsanaka
ASSINATURAISANAKA S
AFILIAÇÕESHarvard University
ORCID0000-0002-4503-2861
VERIFICADOSim
TOTAL DE OBRAS25
TOTAL DE CITAÇÕES0
TOTAL COMO AUTOR25
TOTAL COMO EDITOR0
PRIMEIRO ANO DE PUBLICAÇÃO2012
ANO MAIS RECENTE DE PUBLICAÇÃO2025
ÍNDICE H0

  • The impact of enhancing nutrition and antenatal infection treatment on birth outcomes in Amhara, Ethiopia

    Open AccessAnne CC Lee, Firehiwot Workneh et al.ARTICLEBMJ Global Health2025

    INTRODUCTION: We aimed to determine the impact of antenatal interventions to optimise maternal nutrition and infection management on birth outcomes in Ethiopia. METHODS: We conducted a pragmatic, open-label, 2×2 factorial randomised clinical effectiveness study among pregnant women enrolled <24 weeks gestation in 12 rural health centres in Amhara, Ethiopia. Eligible health centres were randomised to deliver an enhanced nutrition package (ENP) (ir…

  • Effect of caregiver training on knowledge and confidence of at-home clinical and anthropometric surveillance of children with uncomplicated severe acute malnutrition

    Open AccessNazia Binte Ali, Matt D T Hitchings et al.ARTICLEBMJ Global Health2025

    INTRODUCTION: Patient-centred task-shifting models may be a promising strategy in the community-based management of severe acute malnutrition (SAM) to alleviate pressure on health systems and increase access to treatment in low-resource settings. The engagement of caregivers in clinical and anthropometric surveillance has not been evaluated. OBJECTIVES: We examined the effect of caregiver training on their knowledge and confidence in at-home clin…

  • Effect of prenatal multiple micronutrient supplements and medium-quantity lipid-based nutritional supplements on maternal weight gain and infant birth weight in rural Niger

    Open AccessSusan M Rattigan, Souna Garba et al.ARTICLEBMJ Global Health2025

    INTRODUCTION: The risk of adverse birth outcomes, such as low birth weight ( 0.05). We found no effect of MMN or MQ-LNS on maternal haemoglobin concentration or anaemia in the second and third trimesters (p values >0.05). CONCLUSION: There was no statistically significant difference in birth weight, maternal weight gain or anaemia by prenatal nutritional supplementation strategy. However, statistical power in the trial was limited. A combination …

  • Re-thinking “non-response” to wasting treatment

    Open AccessCécile Cazes, Heather Stobaugh et al.ARTICLEPLOS Global Public Health2025

    Children who receive therapeutic feeding for wasting treatment but do not reach the anthropometric definitions of recovery (usually within 12–16 weeks) are categorised as ‘non-responders’ and considered as treatment failures. We conducted a pooled analysis to explore the growth trajectories of non-responders and the appropriateness of the definition of ‘non-response’. We pooled 14 studies of children aged 6–59 months receiving treatment for wasti…

  • Prognostic value of different anthropometric indices over different measurement intervals to predict mortality in 6–59-month-old children

    Open AccessAndré Briend, Mark Myatt et al.ARTICLEPublic Health Nutrition2023

    Objective: To compare the prognostic value of mid-upper arm circumference (MUAC), weight-for-height Z -score (WHZ) and weight-for-age Z -score (WAZ) for predicting death over periods of 1, 3 and 6 months follow-up in children. Design: Pooled analysis of twelve prospective studies examining survival after anthropometric assessment. Sensitivity and false-positive ratios to predict death within 1, 3 and 6 months were compared for three individual an…

  • Conceptualising factors impacting nutrition services coverage of treatment for acute malnutrition in children

    Open AccessStephen R Kodish, B Allen et al.ARTICLEPublic Health Nutrition2023

    Objective: The Three Delays Model is a conceptual model traditionally used to understand contributing factors of maternal mortality. It posits that most barriers to health services utilisation occur in relation to one of three delays: (1) Delay 1: delayed decision to seek care; (2) Delay 2: delayed arrival at health facility and (3) Delay 3: delayed provision of adequate care. We applied this model to understand why a community-based management o…

  • Anthropometric criteria for best-identifying children at high risk of mortality

    Open AccessTanya Khara, Mark Myatt et al.ARTICLEPublic Health Nutrition2023

    Objective: To understand which anthropometric diagnostic criteria best discriminate higher from lower risk of death in children and explore programme implications. Design: A multiple cohort individual data meta-analysis of mortality risk (within 6 months of measurement) by anthropometric case definitions. Sensitivity, specificity, informedness and inclusivity in predicting mortality, face validity and compatibility with current standards and prac…

  • Cost-effectiveness of monthly follow-up for the treatment of uncomplicated severe acute malnutrition

    Open AccessNicolas A Menzies, Fatou Berthé et al.ARTICLEPLOS Global Public Health2022

    Severe acute malnutrition (SAM) is a major source of mortality for children in low resource settings. Alternative treatment models that improve acceptability and reduce caregiver burden are needed to improve treatment access. We assessed costs and cost-effectiveness of monthly vs. weekly follow-up (standard-of-care) for treating uncomplicated SAM in children 6–59 months of age. To do so, we conducted a cost-effectiveness analysis of a cluster-ran…

  • Burden and risk factors for relapse following successful treatment of uncomplicated severe acute malnutrition in young children

    Open AccessLilia Bliznashka, Kyra H Grantz et al.ARTICLEMaternal and Child Nutrition2022

    This study aimed to quantify the burden of relapse following successful treatment for uncomplicated severe acute malnutrition (SAM) and to identify associated risk factors in rural Niger. We used data from 1490 children aged 6-59 months discharged as recovered from an outpatient nutritional programme for SAM and followed for up to 12 weeks after admission. Postdischarge SAM relapse was defined as weight-for-height Z-score <-3, mid-upper arm circu…

  • Acceptability of 11 fortified balanced energy‐protein supplements for pregnant women in Nepal

    Open AccessTsering Pema Lama, Subarna K Khatry et al.ARTICLEMaternal and Child Nutrition2022

    Evidence suggests that multiple micronutrient and balanced energy protein (BEP) supplementation during pregnancy can decrease the risk of stillbirth and small-for-gestational-age births and increase birth weight. We conducted a mixed-methods formative research study to identify the most acceptable among a range of 11 candidates fortified BEP supplements for use in pregnancy and lactation in a rural district in Nepal. Forty pregnant women aged 15-…

  • Improving estimates of the burden of severe wasting

    Open AccessSheila Isanaka, Christopher T Andersen et al.ARTICLEBMJ Global Health2021

    INTRODUCTION: Estimates of incident cases of severe wasting among young children are not available for most settings but are needed for optimal planning of treatment programmes and burden estimation. To improve programme planning, global guidance recommends a single 'incidence correction factor' of 1.6 be applied to available prevalence estimates to account for incident cases. This study aimed to update estimates of the incidence correction facto…

  • Prenatal dietary diversity may influence underweight in infants in a Ugandan birth‐cohort

    Open AccessIsabel Madzorera, Shibani Ghosh et al.ARTICLEMaternal and Child Nutrition2021

    Growth faltering in early childhood is prevalent in many low resource countries. Poor maternal dietary diversity during pregnancy has been linked with increased risk of fetal growth failure and adverse birth outcomes but may also influence subsequent infant growth. Our aim is to assess the role of prenatal maternal dietary diversity in infant growth in rural Uganda. Data from 3291 women and infant pairs enrolled in a birth cohort from 2014 to 201…

  • Compliance with and acceptability of two fortified balanced energy protein supplements among pregnant women in rural Nepal

    Open AccessTsering Pema Lama, Katie Moore et al.ARTICLEMaternal and Child Nutrition2021

    Some evidence suggests that balanced energy protein (BEP) supplements taken during pregnancy and lactation can have positive effects on birth outcomes such as small-for-gestational age and birthweight, but more evidence is needed on the long-term use and acceptability of such supplements. We conducted a mixed-methods formative research study to assess and compare compliance with and acceptability of two BEP supplements, a lipid-based peanut paste…

  • Home consumption of two fortified balanced energy protein supplements by pregnant women in Burkina Faso

    Open AccessBrenda de Kok, Katie Moore et al.ARTICLEMaternal and Child Nutrition2021

    Balanced energy protein (BEP) supplementation for pregnant and lactating women in low- and middle-income countries is a promising strategy to improve birth outcomes and child growth. The objective of this study was to assess and compare the acceptability of new formulations of two fortified BEP supplements, a lipid-based peanut paste and a vanilla biscuit, among 80 pregnant women in rural Burkina Faso, prior to an efficacy trial. A 10-week indivi…

  • Exploring the relationships between wasting and stunting among a cohort of children under two years of age in Niger

    Open AccessKristin Kohlmann, Christopher R Sudfeld et al.ARTICLEBMC Public Health2021

    ClinicalTrials.gov Identifier: NCT02145000

  • Energy needs in the treatment of uncomplicated severe acute malnutrition

    Open AccessSheila Isanaka, Christopher T Andersen et al.ARTICLEMaternal and Child Nutrition2020

    Outpatient therapeutic feeding protocols for the treatment of uncomplicated severe acute malnutrition in children were initially based on weight gain data from inpatient settings and expert knowledge of the physiological requirements during recovery. However, weight gain and energy requirements from historic inpatient settings may differ from modern outpatient settings and therefore may not be appropriate to guide current therapeutic feeding prot…

  • Acceptability of 12 fortified balanced energy protein supplements ‐ Insights from Burkina Faso

    Open AccessLeslie Jones, Brenda de Kok et al.ARTICLEMaternal and Child Nutrition2020

    Poor maternal nutrition contributes to poor birth outcomes, including low birth weight and small for gestational age births. Fortified balanced energy protein (BEP) supplements may be beneficial, although evidence is limited. This mixed method study, conducted among pregnant women in Burkina Faso, is part of a larger clinical trial that seeks to understand the impact of fortified BEP supplements on pregnancy outcomes and child growth. The formati…

  • Linear growth faltering and the role of weight attainment

    Open AccessSheila Isanaka, Matt D T Hitchings et al.ARTICLEMaternal and Child Nutrition2019

    Efforts to reduce the impact of stunting have been largely independent of interventions to reduce the impact of wasting, despite the observation that the conditions can coexist in the same child and increase risk of death. To optimize the management of malnourished children-who can be wasted, stunted, or both-the relationship between stunting and wasting should be elaborated. We aimed to describe the relationship between concurrent weight and hei…

  • Feasibility of engaging caregivers in at‐home surveillance of children with uncomplicated severe acute malnutrition

    Open AccessSheila Isanaka, Fatou Berthé et al.ARTICLEMaternal and Child Nutrition2019

    Many factors can contribute to low coverage of treatment for severe acute malnutrition (SAM), and a limited number of health facilities and trained personnel can constrain the number of children that receive treatment. Alternative models of care that shift the responsibility for routine clinical and anthropometric surveillance from the health facility to the household could reduce the burden of care associated with frequent facility-based visits …

  • Determinants of dietary practices during pregnancy

    Open AccessJoseph G Rosen, Adrienne Clermont et al.ARTICLEMaternal and Child Nutrition2018

    Undernutrition is associated with maternal morbidity and poor pregnancy outcomes. This qualitative study seeks to understand the multilevel factors influencing maternal dietary practices in Niger, including the impact of pregnancy illnesses on diet. Criterion-based, purposive sampling was used to select pregnant women and household members from 24 villages in a rural district of the Maradi Region in south-central Niger. Semistructured interviews …

  • Muac as the sole discharge criterion from community‐based management of severe acute malnutrition in Burkina Faso

    Open AccessSheila Isanaka, Kerstin E Hanson et al.ARTICLEMaternal and Child Nutrition2018

    The use of mid upper arm circumference (MUAC) measurement to screen and determine eligibility for admission to therapeutic feeding programs has been established, but evidence and programmatic experience to inform guidance on the use of MUAC as a discharge criterion is limited. We present results from a large-scale nutritional program using MUAC for admission and discharge and compare program outcomes and response to treatment when determining eli…

  • Cost analysis of the treatment of severe acute malnutrition in West Africa

    Open AccessSheila Isanaka, Nicolas A Menzies et al.ARTICLEMaternal and Child Nutrition2016

    We present an updated cost analysis to provide new estimates of the cost of providing community-based treatment for severe acute malnutrition, including expenditure shares for major cost categories. We calculated total and per child costs from a provider perspective. We categorized costs into three main activities (outpatient treatment, inpatient treatment, and management/administration) and four cost categories within each activity (personnel; t…

  • Gender differences in diet and nutrition among adults initiating antiretroviral therapy in Dar es Salaam, Tanzania

    Ajibola Ibraheem Abioye, Sheila Isanaka et al.ARTICLEAIDS Care2015

    Human immunodeficiency virus (HIV)-infected males have poor treatment outcomes after initiation of antiretroviral therapy (ART) compared to HIV-infected women. Dietary factors might mediate the association between sex and disease progression. However, the gender difference in diet among HIV-infected individuals in sub-Saharan Africa is largely unknown. The objective of this study was to examine differences in dietary intake among HIV-infected men…

  • Comparison of weight-for-height and mid-upper arm circumference (Muac) in a therapeutic feeding programme in South Sudan

    Open AccessEmmanuel Grellety, L Kendall Krause et al.ARTICLEPublic Health Nutrition2015

    Objective The present study was performed to describe the operational implications of using mid-upper arm circumference (MUAC) as a single admission criterion for treatment of severe acute malnutrition in South Sudan. Design We performed a retrospective analysis of routine programme data of children with severe acute malnutrition aged 6–59 months admitted to a therapeutic feeding programme using weight-for-height Z -score (WHZ) and/or MUAC. To un…

  • Post‐natal anaemia and iron deficiency in HIV‐infected women and the health and survival of their children

    Open AccessSheila Isanaka, Donna Spiegelman et al.ARTICLEMaternal and Child Nutrition2012

    Prenatal iron supplementation may improve pregnancy outcomes and decrease the risk of child mortality. However, little is known about the importance of post-natal maternal iron status for child health and survival, particularly in the context of HIV infection. We examined the association of maternal anaemia and hypochromic microcytosis, an erythrocyte morphology consistent with iron deficiency, with child health and survival in the first two to f…