Shoichiro Tsugane
Biographic Data
| ID | 5458957 |
|---|---|
| NAME | Shoichiro Tsugane |
| GIVEN NAMES | Shoichiro |
| FAMILY NAME | Tsugane |
| SIGNATURE | TSUGANE S |
| AFFILIATIONS | National Cancer Centre Japan |
| ORCID | 0000-0003-4105-2774 |
| VERIFIED | Yes |
| TOTAL WORKS | 32 |
| TOTAL CITATIONS | 6 |
| AUTHOR COUNT | 32 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1991 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 2 |
Mental disorders, cancers, and cardiovascular diseases mediate the associations of psychosocial factors with well-being and ikigai: A population-based cohort study
While the role of psychosocial factors in well-being appears plausible, evidence is still limited in Asian populations, and the underlying mechanisms remain unclear. We applied the g-formula to JPHC-NEXT data to examine the longitudinal association of social support, social trust, and social network (assessed via marital status, contact with relatives, contacts with friends, and group associations) at baseline with well-being and ikigai (purpose …
Pufa, fish intake and risk of disabling dementia in Japan: The Japan Public Health Centre Disabling Dementia Study
Objective: The aim of this study was to assess the association between fish intake, n -3 PUFA, n -6 PUFA and risk of disabling dementia. Design: Prospective cohort. Setting: Municipalities within the Japan Public Health Centre-based Prospective Study. Participants: 43 651 participants: (20 002 men and 23 649 women). Results: Exposure intake of fish, n -3 and n -6 PUFA was evaluated in 1995–1997. We defined disabling dementia cases as participants…
Association between the number of social roles and self-rated health: Mediation effect by ikigai and the size of close social networks
Background Health effects of multiple role occupancy and their mechanism are not fully addressed. We examined (1) the association between the number of social roles and self-rated health (SRH) and (2) the mediation effects of ikigai (the sense of life worth living) and the size of close social networks to the association. Methods We analysed the cross-sectional baseline questionnaire data of the Japan Public Health Center-based Prospective Study …
Worldwide trends in underweight and obesity from 1990 to 2022: A pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…
Dietary behaviours and related lifestyles according to the presence or absence of skipping breakfast in Japanese adults: The JPHC-Next study
Objective: To assess dietary behaviours and related lifestyles according to the presence or absence of skipping breakfast. Design: We analysed the cross-sectional data from a baseline survey of a large-scale population-based cohort study in Japan conducted in 2011–2016. Participants provided information on dietary behaviours and lifestyles through a self-administered questionnaire. Skipping breakfast was defined as not eating breakfast at least o…
Perceived Level of Life Enjoyment and Risk of Developing Disabling Dementia: The Japan Public Health Center–Based Study
A higher level of life enjoyment was associated with a lower risk of disabling dementia, particularly in the low-medium mental stress group. This finding suggests the importance of having life enjoyment by managing mental stress for reducing risk of disabling dementia
Long-term exposure to fine particle matter and all-cause mortality and cause-specific mortality in Japan: The JPHC Study
We found evidence for a positive association between PM 2.5 exposure and mortality from cardiovascular disease in a Japanese population, even in an area with relatively low-level air pollution
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: A pooled analysis of 1201 population-representative studies with 104 million participants
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…
Associations of physical activity in rural life with happiness and ikigai: A cross-sectional study
Physical activity is associated with subjective well-being. In rural communities, however, physical activity may be affected by environmental factors (e.g., nature and socioecological factors). We examined the association of two physical activities in rural life (farming activity and snow removal) with subjective well-being in terms of happiness and ikigai (a Japanese word meaning purpose in life). In this cross-sectional study, we analysed data …
Education, household income, and depressive symptoms in middle-aged and older Japanese adults
Both education and household income levels are independently associated with the prevalence of depressive symptoms, with household income levels showing a more robust association with depressive symptoms than education levels. This suggests that a high household income level may offset the risk of depressive symptoms from having a low education level
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: A pooled analysis of 2181 population-based studies with 65 million p…
BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and …
BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. METHODS: We pooled 2416 population-based studies with measurements of height…
Death by Suicide and Other Externally Caused Injuries After Stroke in Japan (1990–2010): The Japan Public Health Center–Based Prospective Study
OBJECTIVE: No large population-based prospective study has investigated the risks of suicide and death by other externally caused injuries (ECIs) among stroke patients. The purpose of this study was to examine whether stroke increases the risks of suicide and ECI deaths. METHODS: We analyzed data from the Japan Public Health Center-based Prospective Study between 1990 and 2010. Poisson regression models were used to calculate adjusted risk ratios…
Neighborhood contextual factors for smoking among middle-aged Japanese: A multilevel analysis
Association between parity and dentition status among Japanese women: Japan public health center-based oral health study
Higher-parity women are more likely to lose teeth, especially posterior occluding relations. These results suggest that measures to narrow the discrepancy by parity should be taken for promoting women's oral health. Delivery of appropriate information and messages to pregnant women as well as enlightenment of oral health professionals about dental management of pregnant women may be an effective strategy
Validation of a quantitative FFQ for a study of diet and risk of colorectal adenoma among Japanese Brazilians
Objective To assess the validity of a 161-item quantitative FFQ (QFFQ) that was developed to evaluate dietary risk factors for a colorectal adenoma case–control study. Design A cross-sectional validation study of the QFFQ against 4 d food diary using Pearson correlation coefficients, cross-classification, weighted κ statistics and Bland–Altman plotting. Setting Two hospitals in São Paulo, Brazil. Subjects Ninety-seven healthy Japanese-Brazilian a…
Impact of alcohol intake on total mortality and mortality from major causes in Japan: A pooled analysis of six large-scale cohort studies
OBJECTIVES: Using common alcohol consumption categories, to conduct a pooled analysis of six ongoing large-scale cohort studies in Japan in order to produce concrete estimates of the quantitative contribution of alcohol consumption to all-cause and major causes of mortality in the Japanese population. METHODS: Of the 309 082 subjects, there were 35 801 deaths during 3 832 285 person-years of follow-up. Using a random-effect model, we conducted a …
What has made the population of Japan healthy?
Use of vitamin supplements and risk of total cancer and cardiovascular disease among the Japanese general population: A population-based survey
To our knowledge, this is the first prospective cohort study to examine simultaneously the associations between vitamin supplement use patterns and risk of cancer and CVD. This prospective cohort study demonstrated that vitamin supplement use has little effect on the risk of cancer or CVD in men. In women, however, consistent vitamin supplement use might reduce the risk of CVD. Elevated risk of cancer associated with past and recent use of vitami…
P1-348 Leisure-time physical activity and breast cancer risk defined by oestrogen and progesterone receptor status: The Japan public health center-based prospective study
Objective To investigate the association between leisure-time physical activity (LPA) and breast cancer risk in consideration of tumour oestrogen/progesterone-receptor (ER/PR) status. Methods We conducted a population-based prospective cohort study among 53 578 women in the Japan Public Health Center-based Prospective Study. LPA was assessed by self-reported questionnaires. A Cox proportional hazards regression model was used to derive RRs and 95…
Gender difference in the association between social support and metabolic syndrome in Japan: The ‘enkai’ effect
BACKGROUND: Recent reports have found an association between social support and reduced prevalence of metabolic syndrome (or its components) in the West; however, no study has been carried out in Asian populations. METHODS: The authors examined 12,537 men and women who were part of the Japan Public Health Center-based Prospective Study initiated in 1993. Perceived emotional support was assessed through questionnaire as receipt of confidant suppor…
P2-214 Rice intake and type 2 diabetes in Japanese men and women: The Japan Public Health Center-Based Prospective Study
Introduction Refined carbohydrates have been suggested to deteriorate glucose metabolism; however, whether persons with elevated intakes of white rice, a major staple food for the Japanese, experience increased risk of developing type 2 diabetes remains unclear. We prospectively investigated the association between white rice intake and risk of type 2 diabetes. Methods Participants were 25 666 men and 33 622 women aged 45–75 years who participate…
Association of weight change in different periods of adulthood with risk of type 2 diabetes in Japanese men and women: The Japan Public Health Center-Based Prospective Study
BACKGROUND: Few studies have examined the impact of weight change in different periods of lifetime on type 2 diabetes risk, and the association of weight loss with type 2 diabetes is unclear. We prospectively investigated the association of weight change since age 20 y and that during middle-to-late adulthood with the incidence of type 2 diabetes. METHODS: Subjects were 52,014 men and women aged 45-75 y who participated in the Japan Public Health…
P2-338 Association of body mass index with risk of age-related cataracts in a middle-aged Japanese population
Introduction Many epidemiological studies have demonstrated that body mass index (BMI) is associated with the risk of developing age-related cataracts. These reports have suggested that high and low BMIs can affect the onset or progression of age-related visual impairment. However, few prospective studies have examined this relationship in a general Asian population. Therefore, in this study, we investigated whether BMI was associated with increa…
Impact of alcohol intake on total mortality and mortality from major causes in Japan: A pooled analysis of six large-scale cohort studies
OBJECTIVES: Using common alcohol consumption categories, to conduct a pooled analysis of six ongoing large-scale cohort studies in Japan in order to produce concrete estimates of the quantitative contribution of alcohol consumption to all-cause and major causes of mortality in the Japanese population. METHODS: Of the 309 082 subjects, there were 35 801 deaths during 3 832 285 person-years of follow-up. Using a random-effect model, we conducted a …
Gender difference in the association between social support and metabolic syndrome in Japan: The ‘enkai’ effect
BACKGROUND: Recent reports have found an association between social support and reduced prevalence of metabolic syndrome (or its components) in the West; however, no study has been carried out in Asian populations. METHODS: The authors examined 12,537 men and women who were part of the Japan Public Health Center-based Prospective Study initiated in 1993. Perceived emotional support was assessed through questionnaire as receipt of confidant suppor…
Neighborhood contextual factors for smoking among middle-aged Japanese: A multilevel analysis
Proportional cancer incidence according to selected sites: Comparison between residents in the City of S. Paulo, Brazil: Japanese and Brazilian/Portuguese descent
The percentual distributions of selected sites of cancer cases according to origin, sex and age are compared. Data were obtained from the Registry of Cancer of S. Paulo (School of Public Health of the University of S. Paulo, Brazil). The reference period for inhabitants of Japanese descent was 1969/78 and for those of Brazilian descent, the period was 1969/75. Standardized Proportionate Incidence Ratios (SPIR) with approximate 95% Confidence Inte…
Seasonal misclassification error and magnitude of true between-person variation in dietary nutrient intake: A random coefficients analysis and implications for the Japan Public Health Center (JPHC) Co…
Objective: We examine (1) the extent to which seasonal diet assessments correctly classify individuals with respect to their usual nutrient intake, and (2) whether the magnitude of true variation in intake between individuals is seasonal. These effects could lead, respectively, to bias in estimates of relative risk for associations between usual nutrient exposure and disease, and to an increase in required sample size. Subjects and setting: One h…
Public awareness of risk factors for cancer among the Japanese general population: A population-based survey
Our results suggest that awareness of the attributable fraction of cancer causes in the Japanese general population tends to be dominated by cancer-causing infection, occupational exposure, air pollution and food additives rather than major lifestyle factors such as diet
Education level and physical functional limitations among Japanese community residents-gender difference in prognosis from stroke
Low education level was associated with the higher prevalence of physical functional limitations for both genders. That association among persons with history of stroke was observed for men but not for women probably due to gender differences in stroke subtypes and social support
The effects of smoking and smoking cessation on mortality from cardiovascular disease among Japanese: Pooled analysis of three large-scale cohort studies in Japan
The present study confirmed the association between smoking and mortality from cardiovascular disease in both males and females. Smoking cessation is a crucial preventive measure against death from cardiovascular disease
Impact of weight change on specific-cause mortality among middle-aged Japanese individuals
BACKGROUND: The aim of this study was to investigate the associations between long-term weight change after age 20 and overall mortality and cause-specific mortality in the general Asian population. METHODS: From 1990 to 2005, the Japan Public Health Center (JPHC)-based prospective study conducted a follow-up of 42 242 men and 46 177 women aged 40-69 years with no history of cardiovascular disease (CVD) or cancer. Sex-specific multivariable-adjus…
What has made the population of Japan healthy?
Use of vitamin supplements and risk of total cancer and cardiovascular disease among the Japanese general population: A population-based survey
To our knowledge, this is the first prospective cohort study to examine simultaneously the associations between vitamin supplement use patterns and risk of cancer and CVD. This prospective cohort study demonstrated that vitamin supplement use has little effect on the risk of cancer or CVD in men. In women, however, consistent vitamin supplement use might reduce the risk of CVD. Elevated risk of cancer associated with past and recent use of vitami…
P1-348 Leisure-time physical activity and breast cancer risk defined by oestrogen and progesterone receptor status: The Japan public health center-based prospective study
Objective To investigate the association between leisure-time physical activity (LPA) and breast cancer risk in consideration of tumour oestrogen/progesterone-receptor (ER/PR) status. Methods We conducted a population-based prospective cohort study among 53 578 women in the Japan Public Health Center-based Prospective Study. LPA was assessed by self-reported questionnaires. A Cox proportional hazards regression model was used to derive RRs and 95…
Gender difference in the association between social support and metabolic syndrome in Japan: The ‘enkai’ effect
BACKGROUND: Recent reports have found an association between social support and reduced prevalence of metabolic syndrome (or its components) in the West; however, no study has been carried out in Asian populations. METHODS: The authors examined 12,537 men and women who were part of the Japan Public Health Center-based Prospective Study initiated in 1993. Perceived emotional support was assessed through questionnaire as receipt of confidant suppor…
P2-214 Rice intake and type 2 diabetes in Japanese men and women: The Japan Public Health Center-Based Prospective Study
Introduction Refined carbohydrates have been suggested to deteriorate glucose metabolism; however, whether persons with elevated intakes of white rice, a major staple food for the Japanese, experience increased risk of developing type 2 diabetes remains unclear. We prospectively investigated the association between white rice intake and risk of type 2 diabetes. Methods Participants were 25 666 men and 33 622 women aged 45–75 years who participate…
Association of weight change in different periods of adulthood with risk of type 2 diabetes in Japanese men and women: The Japan Public Health Center-Based Prospective Study
BACKGROUND: Few studies have examined the impact of weight change in different periods of lifetime on type 2 diabetes risk, and the association of weight loss with type 2 diabetes is unclear. We prospectively investigated the association of weight change since age 20 y and that during middle-to-late adulthood with the incidence of type 2 diabetes. METHODS: Subjects were 52,014 men and women aged 45-75 y who participated in the Japan Public Health…
P2-338 Association of body mass index with risk of age-related cataracts in a middle-aged Japanese population
Introduction Many epidemiological studies have demonstrated that body mass index (BMI) is associated with the risk of developing age-related cataracts. These reports have suggested that high and low BMIs can affect the onset or progression of age-related visual impairment. However, few prospective studies have examined this relationship in a general Asian population. Therefore, in this study, we investigated whether BMI was associated with increa…
P1-446 Comparison of postmenopausal endogenous sex hormones among Japanese, Japanese Brazilians, and non-Japanese Brazilians
Introduction Previous studies have shown higher breast cancer incidence and mortality among Japanese Brazilians than Japanese. To clarify the difference in hormone levels among populations, we compared postmenopausal endogenous sex hormone levels among Japanese living in Japan, Japanese Brazilians living in São Paulo, and non-Japanese Brazilians living in São Paulo. Methods A cross-sectional study was conducted using a control group of case-contr…
Impact of alcohol intake on total mortality and mortality from major causes in Japan: A pooled analysis of six large-scale cohort studies
OBJECTIVES: Using common alcohol consumption categories, to conduct a pooled analysis of six ongoing large-scale cohort studies in Japan in order to produce concrete estimates of the quantitative contribution of alcohol consumption to all-cause and major causes of mortality in the Japanese population. METHODS: Of the 309 082 subjects, there were 35 801 deaths during 3 832 285 person-years of follow-up. Using a random-effect model, we conducted a …
Association between parity and dentition status among Japanese women: Japan public health center-based oral health study
Higher-parity women are more likely to lose teeth, especially posterior occluding relations. These results suggest that measures to narrow the discrepancy by parity should be taken for promoting women's oral health. Delivery of appropriate information and messages to pregnant women as well as enlightenment of oral health professionals about dental management of pregnant women may be an effective strategy
Validation of a quantitative FFQ for a study of diet and risk of colorectal adenoma among Japanese Brazilians
Objective To assess the validity of a 161-item quantitative FFQ (QFFQ) that was developed to evaluate dietary risk factors for a colorectal adenoma case–control study. Design A cross-sectional validation study of the QFFQ against 4 d food diary using Pearson correlation coefficients, cross-classification, weighted κ statistics and Bland–Altman plotting. Setting Two hospitals in São Paulo, Brazil. Subjects Ninety-seven healthy Japanese-Brazilian a…
Death by Suicide and Other Externally Caused Injuries After Stroke in Japan (1990–2010): The Japan Public Health Center–Based Prospective Study
OBJECTIVE: No large population-based prospective study has investigated the risks of suicide and death by other externally caused injuries (ECIs) among stroke patients. The purpose of this study was to examine whether stroke increases the risks of suicide and ECI deaths. METHODS: We analyzed data from the Japan Public Health Center-based Prospective Study between 1990 and 2010. Poisson regression models were used to calculate adjusted risk ratios…
Neighborhood contextual factors for smoking among middle-aged Japanese: A multilevel analysis
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: A pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and …
BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. METHODS: We pooled 2416 population-based studies with measurements of height…
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories: A pooled analysis of 2181 population-based studies with 65 million p…
BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: A pooled analysis of 1201 population-representative studies with 104 million participants
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…
Associations of physical activity in rural life with happiness and ikigai: A cross-sectional study
Physical activity is associated with subjective well-being. In rural communities, however, physical activity may be affected by environmental factors (e.g., nature and socioecological factors). We examined the association of two physical activities in rural life (farming activity and snow removal) with subjective well-being in terms of happiness and ikigai (a Japanese word meaning purpose in life). In this cross-sectional study, we analysed data …
Education, household income, and depressive symptoms in middle-aged and older Japanese adults
Both education and household income levels are independently associated with the prevalence of depressive symptoms, with household income levels showing a more robust association with depressive symptoms than education levels. This suggests that a high household income level may offset the risk of depressive symptoms from having a low education level
Medicine (31 works) · Demography (25 works) · Environmental health (18 works) · Internal Medicine (18 works) · Population (16 works) · Cohort (13 works) · Cohort study (13 works) · Gerontology (11 works) · Internal Medicine (11 works) · Confidence interval (10 works)