Karim Manji
Datos Biográficos
| ID | 5460664 |
|---|---|
| NOMBRE | Karim Manji |
| NOMBRES | Karim |
| APELLIDO | Manji |
| FIRMA | MANJI K |
| AFILIACIONES | Muhimbili University of Health and Allied Sciences |
| ORCID | 0000-0002-7069-6408 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 21 |
| TOTAL DE CITAS | 0 |
| TOTAL COMO AUTOR | 21 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2012 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 0 |
Predictive and concurrent validity of caregiver reported early childhood development assessments
Many directly assessed and caregiver-reported measures of early childhood development (ECD) are used to monitor outcomes and evaluate interventions in low- and middle-income countries (LMICs). Many assessments of ECD for children 0–3 years old have robust psychometric properties, but relatively little is known about their ability to predict later developmental and learning outcomes. To address questions about predictive and concurrent validity, w…
Developing paediatric subspecialty training in resource-limited settings; the first neonatology subspeciality program in Tanzania
BACKGROUND: Neonatal mortality remains high in Tanzania, where progress toward Sustainable Development Goal 3.2 is constrained by a severe shortage of trained workforce. To achieve the goal, Tanzania, with approximately two million annual births, aims to reduce neonatal mortality from 24 to fewer than 12 deaths per 1,000 live births by 2030. In 2020, only five neonatologists, including expatriates, were available nationwide. To fill this gap, the…
We discovered new ways of learning’
BACKGROUND: Children with disabilities face many barriers to early childhood development services and to pre-primary education. Evidence on inclusive school readiness and community-based approaches in low- and middle-income countries (LMICs) still remains limited. OBJECTIVE: To explore the feasibility and acceptability of a co-designed training programme for caregivers to support school readiness among children aged 4-6 years in Bangladesh, Nepal…
Is rotavirus aetiology in young children with acute diarrhoea associated with sociodemographic and clinical factors, including rotavirus vaccination status? A secondary cross-sectional analysis of the…
INTRODUCTION: One of the leading causes of global child mortality continues to be diarrhoea where rotavirus contributed to about 24% of deaths among all diarrhoeal deaths, mostly in low-income and middle-income countries. Rotavirus vaccination programmes have contributed to the reduction of mortality from 24% to 19% in rotavirus infections among hospitalised children, but the burden of rotaviral diarrhoea remains high, especially in settings with…
Systematic review of risk assessment tools for post-discharge mortality among children in sub-Saharan Africa
Post-discharge mortality is increasingly recognized as a major contributor to the high burden of childhood mortality in sub-Saharan Africa. Accurate identification of children at risk for post-discharge mortality is critically important to inform interventions to reduce deaths following hospital discharge. Our objective was to describe the current state of development, validation, or implementation for risk assessment tools for post-hospital disc…
Assessing Covid-19 seroprevalence and vaccine uptake among women of reproductive-age in Zanzibar’s archipelago
Recent events in public health globally have created a need for response by public health researchers in all disciplines to evaluate impact on health, morbidity and mortality of the COVID-19 pandemic that has engulfed the world after 100 years of previous influenza pandemic. Most of the immediate responses, globally; have focused on diagnosis and management of severe cases. However, for evolution of policies dealing with population health in the …
Characteristics and outcomes of children 2–23 months of age with prolonged diarrhoea
Background: Approximately 12% of all diarrhoeal episodes last for 7-13 days. As such, they are termed prolonged diarrhoea, and are associated with over two-thirds of all diarrhoeal deaths. Due to a lack of robust data, we aimed to evaluate a comparative background characteristics of young children with acute and prolonged diarrhoea, and their outcomes at day 90 follow-up. Methods: We performed a secondary analysis of data from the Antibiotics for…
Facility-based care for moderately low birthweight infants in India, Malawi, and Tanzania
Globally, increasing rates of facility-based childbirth enable early intervention for small vulnerable newborns. We describe health system-level inputs, current feeding, and discharge practices for moderately low birthweight (MLBW) infants (1500- 10% less than their birthweight; 18.8% of infants were discharged with weights below facility-specific policy [1800g in India, 1500g in Malawi, and 2000g in Tanzania]. Based on descriptive analysis, we f…
Safe infant feeding in healthcare facilities
Infants need to receive care in environments that limit their exposure to pathogens. Inadequate water, sanitation, and hygiene (WASH) environments and suboptimal infection prevention and control practices in healthcare settings contribute to the burden of healthcare-associated infections, which are particularly high in low-income settings. Specific research is needed to understand infant feeding preparation in healthcare settings, a task involvin…
A cross-sectional analysis of publication of pediatric global health abstracts from seven major international conferences
Research presented at conferences may increase context-specific evidence in low- and middle-income countries (LMICs), where global childhood disease burden is greatest and where massive relative deficits in research persist. Publication of studies presented at conferences is necessary for complete results dissemination. Our objective was to determine the frequency of publication of pediatric global health conference abstracts and to identify fact…
Associations Between Social Support and Symptoms of Antenatal Depression with Infant Growth and Development Among Mothers Living with HIV in Tanzania
Authorship equity guidelines in global health journals
Background Thrombectomy for acute ischemic stroke treatment leads to improved outcomes, but many patients do not achieve a good outcome despite successful reperfusion. We determined predictors of poor outcome after successful thrombectomy (TICI 2b–3) with an emphasis on modifiable factors. Methods Patients from the randomized DEFUSE 3 trial who underwent thrombectomy with TICI 2b–3 revascularization were included. Primary outcome was a poor outco…
Cost-effectiveness of zinc supplementation for prevention of childhood diarrhoea in Tanzania
Objective: To assess the cost-effectiveness of prophylactic Zn supplementation for preventing diarrhoea in young children in Tanzania. Design: Cost-effectiveness analysis using decision-analytic modelling. Cost-effectiveness ratios were calculated as the incremental cost (2019 USD) per disability-adjusted life year (DALY) averted, from a societal perspective, and with a 3 % discount rate applied to future outcomes. Sensitivity analyses were perfo…
Where there is no local author
INTRODUCTION: Authorship parasitism (ie, no authors affiliated with the country in which the study took place) occurs frequently in research conducted in low-income and middle-income countries, despite published recommendations defining authorship criteria. The objective was to compare characteristics of articles exhibiting authorship parasitism in sub-Saharan Africa to articles with author representation from sub-Saharan African countries. METHO…
Maternal pesticide exposure and child neuro-development among smallholder tomato farmers in the southern corridor of Tanzania
The findings from this study have indicated that maternal pesticide exposure among farmworker residents in the SAGCOT area has a potential association with child developmental effect
Influence of gender norms in relation to child’s quality of care
“Every Newborn-BIRTH” protocol
BACKGROUND: - Birth Indicators Research Tracking in Hospitals (EN-BIRTH) study aims to validate selected newborn and maternal indicators for routine tracking of coverage and quality of facility-based care for use at district, national and global levels. METHODS: EN-BIRTH is an observational study including >20 000 facility births in three countries (Tanzania, Bangladesh and Nepal) to validate selected indicators. Direct clinical observation will …
Factors associated with the decline in under five diarrhea mortality in Tanzania from 1980-2015
BACKGROUND: Tanzania has made great progress in reducing diarrhea mortality in under- five children. We examined factors associated with the decline and projected the impact of scaling up interventions or reducing risk factors on diarrhea deaths. METHODS: We reviewed economic, health, and diarrhea-related policies, reports and programs implemented during 1980 to 2015. We used the Lives Saved Tool to determine the percentage reduction in diarrhea-…
The effect of daily zinc and/or multivitamin supplements on early childhood development in Tanzania
Impaired childhood development has lifelong consequences for educational attainment and wage-earning potential. Micronutrient supplements have the potential to improve development. The objective of this study was to determine the effect of daily zinc and/or multivitamin (vitamins C, E and B-complex) supplements on development among Tanzanian infants. In this randomized, 2 × 2 factorial, double-blind trial, 2400 infants were randomized to zinc (Zn…
Nutritional status and complementary feeding among HIV‐exposed infants
Complementary feeding is crucial for improving child survival and promoting growth and development, particularly among HIV-exposed children who have higher risk of morbidity and mortality than their un-exposed peers. This prospective study employed an infant and child feeding index (ICFI) to measure complementary feeding and determine its association with nutritional status among 2092 HIV-exposed infants followed from 6 to 24 months of age in Dar…
Post‐natal anaemia and iron deficiency in HIV‐infected women and the health and survival of their children
Prenatal iron supplementation may improve pregnancy outcomes and decrease the risk of child mortality. However, little is known about the importance of post-natal maternal iron status for child health and survival, particularly in the context of HIV infection. We examined the association of maternal anaemia and hypochromic microcytosis, an erythrocyte morphology consistent with iron deficiency, with child health and survival in the first two to f…
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Post‐natal anaemia and iron deficiency in HIV‐infected women and the health and survival of their children
Prenatal iron supplementation may improve pregnancy outcomes and decrease the risk of child mortality. However, little is known about the importance of post-natal maternal iron status for child health and survival, particularly in the context of HIV infection. We examined the association of maternal anaemia and hypochromic microcytosis, an erythrocyte morphology consistent with iron deficiency, with child health and survival in the first two to f…
The effect of daily zinc and/or multivitamin supplements on early childhood development in Tanzania
Impaired childhood development has lifelong consequences for educational attainment and wage-earning potential. Micronutrient supplements have the potential to improve development. The objective of this study was to determine the effect of daily zinc and/or multivitamin (vitamins C, E and B-complex) supplements on development among Tanzanian infants. In this randomized, 2 × 2 factorial, double-blind trial, 2400 infants were randomized to zinc (Zn…
Nutritional status and complementary feeding among HIV‐exposed infants
Complementary feeding is crucial for improving child survival and promoting growth and development, particularly among HIV-exposed children who have higher risk of morbidity and mortality than their un-exposed peers. This prospective study employed an infant and child feeding index (ICFI) to measure complementary feeding and determine its association with nutritional status among 2092 HIV-exposed infants followed from 6 to 24 months of age in Dar…
“Every Newborn-BIRTH” protocol
BACKGROUND: - Birth Indicators Research Tracking in Hospitals (EN-BIRTH) study aims to validate selected newborn and maternal indicators for routine tracking of coverage and quality of facility-based care for use at district, national and global levels. METHODS: EN-BIRTH is an observational study including >20 000 facility births in three countries (Tanzania, Bangladesh and Nepal) to validate selected indicators. Direct clinical observation will …
Factors associated with the decline in under five diarrhea mortality in Tanzania from 1980-2015
BACKGROUND: Tanzania has made great progress in reducing diarrhea mortality in under- five children. We examined factors associated with the decline and projected the impact of scaling up interventions or reducing risk factors on diarrhea deaths. METHODS: We reviewed economic, health, and diarrhea-related policies, reports and programs implemented during 1980 to 2015. We used the Lives Saved Tool to determine the percentage reduction in diarrhea-…
Influence of gender norms in relation to child’s quality of care
Where there is no local author
INTRODUCTION: Authorship parasitism (ie, no authors affiliated with the country in which the study took place) occurs frequently in research conducted in low-income and middle-income countries, despite published recommendations defining authorship criteria. The objective was to compare characteristics of articles exhibiting authorship parasitism in sub-Saharan Africa to articles with author representation from sub-Saharan African countries. METHO…
Maternal pesticide exposure and child neuro-development among smallholder tomato farmers in the southern corridor of Tanzania
The findings from this study have indicated that maternal pesticide exposure among farmworker residents in the SAGCOT area has a potential association with child developmental effect
Authorship equity guidelines in global health journals
Background Thrombectomy for acute ischemic stroke treatment leads to improved outcomes, but many patients do not achieve a good outcome despite successful reperfusion. We determined predictors of poor outcome after successful thrombectomy (TICI 2b–3) with an emphasis on modifiable factors. Methods Patients from the randomized DEFUSE 3 trial who underwent thrombectomy with TICI 2b–3 revascularization were included. Primary outcome was a poor outco…
Cost-effectiveness of zinc supplementation for prevention of childhood diarrhoea in Tanzania
Objective: To assess the cost-effectiveness of prophylactic Zn supplementation for preventing diarrhoea in young children in Tanzania. Design: Cost-effectiveness analysis using decision-analytic modelling. Cost-effectiveness ratios were calculated as the incremental cost (2019 USD) per disability-adjusted life year (DALY) averted, from a societal perspective, and with a 3 % discount rate applied to future outcomes. Sensitivity analyses were perfo…
Facility-based care for moderately low birthweight infants in India, Malawi, and Tanzania
Globally, increasing rates of facility-based childbirth enable early intervention for small vulnerable newborns. We describe health system-level inputs, current feeding, and discharge practices for moderately low birthweight (MLBW) infants (1500- 10% less than their birthweight; 18.8% of infants were discharged with weights below facility-specific policy [1800g in India, 1500g in Malawi, and 2000g in Tanzania]. Based on descriptive analysis, we f…
Safe infant feeding in healthcare facilities
Infants need to receive care in environments that limit their exposure to pathogens. Inadequate water, sanitation, and hygiene (WASH) environments and suboptimal infection prevention and control practices in healthcare settings contribute to the burden of healthcare-associated infections, which are particularly high in low-income settings. Specific research is needed to understand infant feeding preparation in healthcare settings, a task involvin…
A cross-sectional analysis of publication of pediatric global health abstracts from seven major international conferences
Research presented at conferences may increase context-specific evidence in low- and middle-income countries (LMICs), where global childhood disease burden is greatest and where massive relative deficits in research persist. Publication of studies presented at conferences is necessary for complete results dissemination. Our objective was to determine the frequency of publication of pediatric global health conference abstracts and to identify fact…
Associations Between Social Support and Symptoms of Antenatal Depression with Infant Growth and Development Among Mothers Living with HIV in Tanzania
Characteristics and outcomes of children 2–23 months of age with prolonged diarrhoea
Background: Approximately 12% of all diarrhoeal episodes last for 7-13 days. As such, they are termed prolonged diarrhoea, and are associated with over two-thirds of all diarrhoeal deaths. Due to a lack of robust data, we aimed to evaluate a comparative background characteristics of young children with acute and prolonged diarrhoea, and their outcomes at day 90 follow-up. Methods: We performed a secondary analysis of data from the Antibiotics for…
Is rotavirus aetiology in young children with acute diarrhoea associated with sociodemographic and clinical factors, including rotavirus vaccination status? A secondary cross-sectional analysis of the…
INTRODUCTION: One of the leading causes of global child mortality continues to be diarrhoea where rotavirus contributed to about 24% of deaths among all diarrhoeal deaths, mostly in low-income and middle-income countries. Rotavirus vaccination programmes have contributed to the reduction of mortality from 24% to 19% in rotavirus infections among hospitalised children, but the burden of rotaviral diarrhoea remains high, especially in settings with…
Systematic review of risk assessment tools for post-discharge mortality among children in sub-Saharan Africa
Post-discharge mortality is increasingly recognized as a major contributor to the high burden of childhood mortality in sub-Saharan Africa. Accurate identification of children at risk for post-discharge mortality is critically important to inform interventions to reduce deaths following hospital discharge. Our objective was to describe the current state of development, validation, or implementation for risk assessment tools for post-hospital disc…
Assessing Covid-19 seroprevalence and vaccine uptake among women of reproductive-age in Zanzibar’s archipelago
Recent events in public health globally have created a need for response by public health researchers in all disciplines to evaluate impact on health, morbidity and mortality of the COVID-19 pandemic that has engulfed the world after 100 years of previous influenza pandemic. Most of the immediate responses, globally; have focused on diagnosis and management of severe cases. However, for evolution of policies dealing with population health in the …
Predictive and concurrent validity of caregiver reported early childhood development assessments
Many directly assessed and caregiver-reported measures of early childhood development (ECD) are used to monitor outcomes and evaluate interventions in low- and middle-income countries (LMICs). Many assessments of ECD for children 0–3 years old have robust psychometric properties, but relatively little is known about their ability to predict later developmental and learning outcomes. To address questions about predictive and concurrent validity, w…
Developing paediatric subspecialty training in resource-limited settings; the first neonatology subspeciality program in Tanzania
BACKGROUND: Neonatal mortality remains high in Tanzania, where progress toward Sustainable Development Goal 3.2 is constrained by a severe shortage of trained workforce. To achieve the goal, Tanzania, with approximately two million annual births, aims to reduce neonatal mortality from 24 to fewer than 12 deaths per 1,000 live births by 2030. In 2020, only five neonatologists, including expatriates, were available nationwide. To fill this gap, the…
We discovered new ways of learning’
BACKGROUND: Children with disabilities face many barriers to early childhood development services and to pre-primary education. Evidence on inclusive school readiness and community-based approaches in low- and middle-income countries (LMICs) still remains limited. OBJECTIVE: To explore the feasibility and acceptability of a co-designed training programme for caregivers to support school readiness among children aged 4-6 years in Bangladesh, Nepal…
Medicine (18 obras) · Pediatrics (12 obras) · Child Nutrition and Water Access (11 obras) · Internal Medicine (11 obras) · Tanzania (11 obras) · Environmental health (10 obras) · Geography (9 obras) · Global Maternal and Child Health (7 obras) · Population (6 obras) · Demography (5 obras)