W Dana Flanders
Biographic Data
| ID | 5460924 |
|---|---|
| NAME | W Dana Flanders |
| GIVEN NAMES | W Dana |
| FAMILY NAME | Flanders |
| SIGNATURE | FLANDERS W D |
| AFFILIATIONS | Emory University |
| ORCID | 0000-0003-4069-3262 |
| VERIFIED | Yes |
| TOTAL WORKS | 20 |
| TOTAL CITATIONS | 97 |
| AUTHOR COUNT | 20 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1982 |
| LATEST PUBLICATION YEAR | 2023 |
| H-INDEX | 4 |
Evaluation of a Novel Ambient Light Survey Question in the Cancer Prevention Study-3
Nighttime light exposure may increase cancer risk by disrupting the circadian system. However, there is no well-established survey method for measuring ambient light. In the Cancer Prevention Study-3, 732 men and women answered a light survey based on seven environments. The light environment in the past year was assessed twice, one year apart, and four one-week diaries were collected between the annual surveys. A total of 170 participants wore a…
Mental Health of Transgender and Gender Nonconforming Youth Compared With Their Peers
BACKGROUND: Understanding the magnitude of mental health problems, particularly life-threatening ones, experienced by transgender and/or gender nonconforming (TGNC) youth can lead to improved management of these conditions. METHODS: Electronic medical records were used to identify a cohort of 588 transfeminine and 745 transmasculine children (3-9 years old) and adolescents (10-17 years old) enrolled in integrated health care systems in California…
Differences in Heat-Related Mortality by Citizenship Status
Objectives. To determine whether non-US citizens have a higher mortality risk of heat-related deaths than do US citizens. Methods. We used place of residence reported in mortality data from the National Vital Statistics System from 2005 to 2014 as a proxy for citizenship to examine differences in heat-related deaths between non-US and US citizens. Estimates from the US Census Bureau American Community Survey of self-reported citizenship status an…
Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults
IMPORTANCE Epidemiologic studies have suggested that higher intake of added sugar is associated with cardiovascular disease (CVD) risk factors. Few prospective studies have examined the association of added sugar intake with CVD mortality. OBJECTIVE To examine time trends of added sugar consumption as percentage of daily calories in the United States and investigate the association of this consumption with CVD mortality. DESIGN, SETTING, AND PART…
Association Between Birthplace and Current Asthma
Objectives. We evaluated associations between current asthma and birthplace among major racial/ethnic groups in the United States. Methods. We used multivariate logistic regression methods to analyze data on 102 524 children and adolescents and 255 156 adults in the National Health Interview Survey (2001–2009). Results. We found significantly higher prevalence (P Conclusions. Current asthma status was positively associated with being born in the …
Race, neighbourhood characteristics and disparities in chemotherapy for colorectal cancer
BACKGROUND: Studies have found significant race/ethnic and age differences in receipt of adjuvant chemotherapy for stages III colon and II/III rectal cancers. Little is known about the role of neighbourhood factors in these disparities. METHODS: The 4748 Black and White patients from the Georgia Comprehensive Cancer Registry were diagnosed with stages III colon and II/III rectal cancers between 2000 and 2004. Neighbourhood poverty, segregation (%…
The issue of confounding in epidemiological studies of ambient air pollution and pregnancy outcomes
BACKGROUND: Relationships between ambient air pollution levels during pregnancy and adverse pregnancy outcomes have been investigated using one of three analytic approaches: ambient pollution levels have been contrasted over space, time or both space and time. Although the three approaches share a common goal, to estimate the causal effects of pollution on pregnancy outcomes, they face different challenges with respect to confounding. METHODS: A …
Associations of Maternal Age- and Parity-Related Factors With Trends in Low-Birthweight Rates
Objectives. We assessed the effects of changes in the maternal age–parity distribution and age-and parity-specific low-birthweight rates on low-birthweight trends in the United States. Methods. We used natality file data from 1980 through 2000 to assess very-low-birthweight and low-birthweight rates among singleton live-born infants. Results. Changes in age-and parity-specific low-birthweight rates were the main contributor to the overall trend i…
Yang Et Al. Respond
We thank Schempf and Becker for pointing out a deficiency in our presentation, although we disagree with their solution. In fact, we were aware of the alternative standards they cite and rejected them as inappropriate. Although researchers are often taught otherwise, the choice of standard distributions is not arbitrary and should not be based on symmetry or other mathematical considerations. Rather, the choice of standard distribution should be …
High-Intensity Targeted Screening for Elevated Blood Lead Levels Among Children in 2 Inner-City Chicago Communities
Objectives. We assessed the prevalence of elevated blood lead levels (≥ 10 micrograms of lead per deciliter of blood), risk factors, and previous blood lead testing among children in 2 high-risk Chicago, Ill, communities. Methods. Through high-intensity targeted screening, blood lead levels were tested and risks were assessed among a representative sample of children aged 1 to 5 years who were at risk for lead exposure. Results. Of the 539 childr…
Método modificado de muestreo por conglomerados para la evaluación rápida de necesidades después de un desastre
El método de muestreo por conglomerados puede utilizarse para llevar a cabo la evaluación rápida de las necesidades de salud y de otro tipo en comunidades afectadas por desastres naturales. El método, que se basa en el modelo usado por el Programa Ampliado de Inmunización de la OMS para estimar la cobertura con vacunación, ha sido modificado para que proporcione 1) estimaciones de la población que queda en una zona determinada y 2) estimaciones d…
Heat-Related Deaths during the July 1995 Heat Wave in Chicago
During a record-setting heat wave in Chicago in July 1995, there were at least 700 excess deaths, most of which were classified as heat-related. We sought to determine who was at greatest risk for heat-related death.
Risk factors for self-reported uterine fibroids
To identify risk factors for uterine fibroids, a case-control design used to analyze data from control subjects enrolled in the Cancer and Steroid Hormone Study. Case patients were 201 women who reported a history of uterine fibroids, and control subjects were 1503 women without fibroids, individually matched by age to case patients. Reporting of fibroids was more frequent among premenopausal women, women who had frequent Papanicolaou (Pap) smear…
Excess mortality among cigarette smokers
OBJECTIVES: This study was undertaken to examine changes in smoking-specific death rates from the 1960s to the 1980s. METHODS: In two prospective studies, one from 1959 to 1965 and the other from 1982 to 1988, death rates from lung cancer, coronary heart disease, and other major smoking-related diseases were measured among more than 200,000 current smokers and 480,000 lifelong non-smokers in each study. RESULTS: From the first to the second study…
Demographic predictors of mammography and Pap smear screening in US women
OBJECTIVES. Proven screening technologies exist for both breast and cervical cancer, but they are underused by many women. We sought to evaluate the effect of demographic characteristics on the underuse of mammography and Pap smear screening. METHODS. We analyzed responses from 12,252 women who participated in the 1987 National Health Interview Survey Cancer Control Supplement. Demographic profiles were produced to target severely underserved gro…
Does increased detection account for the rising incidence of breast cancer
BACKGROUND: The incidence of breast cancer has been increasing over time in the United States. METHODS: To determine the role of screening in this increase, trends in the incidence of in situ and invasive carcinoma of the breast were evaluated using records of the metropolitan Atlanta SEER program between 1979 and 1986. From a sample of records, evidence of symptoms and mammographic screening prior to diagnosis was recorded. RESULTS: The average …
Inappropriate comparisons of incidence and prevalence in epidemiologic research
Several epidemiologists have published papers in major medical journals in which they compare incidence rates and prevalence and use these comparisons to support conclusions regarding questions of major public health importance. Although these papers have been criticized in published correspondence, we believe that continued use and advocacy of such comparisons by some epidemiologists has created the need for a full discussion of this practice. I…
Brain cancer and nonoccupational risk factors
In a nested case-control study of nuclear workers, 82 brain cancer cases were compared with 328 matched controls to investigate the possible association with nonoccupational risk factors such as histories of epilepsy or head injury. We observed a moderately strong association between brain cancer occurrence and history of epilepsy (OR = 5.7, 95 per cent CI: 1.0, 32.1), but did not find a positive association with previous head injury (OR = 0.9, 9…
A comparison of estrogen and progesterone receptors in black and white breast cancer patients
After standardization for age and menopausal status, the prevalence of estrogen receptor positivity among 88 White breast cancer patients was about .72 compared with a prevalence of about .54 among Black patients. The prevalence of progesterone receptor positivity was also higher among White than among Black patients, although the magnitude of the difference was smaller. These differences were unchanged after adjustment for tumor size and nodal a…
Occupational risk for laryngeal cancer
In a case-control analysis, we studied the effects of type of employment on laryngeal cancer risk using the interview data from the Third National Cancer Survey. Effects were measured relative to the risk for those employed in a group of arbitrarily defined industries and occupations with low risk. We excluded females and controlled for age, tobacco use, alcohol use, and race in the analysis. We found ratio estimates above 3.0 for workers in the …
Demographic predictors of mammography and Pap smear screening in US women
OBJECTIVES. Proven screening technologies exist for both breast and cervical cancer, but they are underused by many women. We sought to evaluate the effect of demographic characteristics on the underuse of mammography and Pap smear screening. METHODS. We analyzed responses from 12,252 women who participated in the 1987 National Health Interview Survey Cancer Control Supplement. Demographic profiles were produced to target severely underserved gro…
Excess mortality among cigarette smokers
OBJECTIVES: This study was undertaken to examine changes in smoking-specific death rates from the 1960s to the 1980s. METHODS: In two prospective studies, one from 1959 to 1965 and the other from 1982 to 1988, death rates from lung cancer, coronary heart disease, and other major smoking-related diseases were measured among more than 200,000 current smokers and 480,000 lifelong non-smokers in each study. RESULTS: From the first to the second study…
Associations of Maternal Age- and Parity-Related Factors With Trends in Low-Birthweight Rates
Objectives. We assessed the effects of changes in the maternal age–parity distribution and age-and parity-specific low-birthweight rates on low-birthweight trends in the United States. Methods. We used natality file data from 1980 through 2000 to assess very-low-birthweight and low-birthweight rates among singleton live-born infants. Results. Changes in age-and parity-specific low-birthweight rates were the main contributor to the overall trend i…
Race, neighbourhood characteristics and disparities in chemotherapy for colorectal cancer
BACKGROUND: Studies have found significant race/ethnic and age differences in receipt of adjuvant chemotherapy for stages III colon and II/III rectal cancers. Little is known about the role of neighbourhood factors in these disparities. METHODS: The 4748 Black and White patients from the Georgia Comprehensive Cancer Registry were diagnosed with stages III colon and II/III rectal cancers between 2000 and 2004. Neighbourhood poverty, segregation (%…
High-Intensity Targeted Screening for Elevated Blood Lead Levels Among Children in 2 Inner-City Chicago Communities
Objectives. We assessed the prevalence of elevated blood lead levels (≥ 10 micrograms of lead per deciliter of blood), risk factors, and previous blood lead testing among children in 2 high-risk Chicago, Ill, communities. Methods. Through high-intensity targeted screening, blood lead levels were tested and risks were assessed among a representative sample of children aged 1 to 5 years who were at risk for lead exposure. Results. Of the 539 childr…
Does increased detection account for the rising incidence of breast cancer
BACKGROUND: The incidence of breast cancer has been increasing over time in the United States. METHODS: To determine the role of screening in this increase, trends in the incidence of in situ and invasive carcinoma of the breast were evaluated using records of the metropolitan Atlanta SEER program between 1979 and 1986. From a sample of records, evidence of symptoms and mammographic screening prior to diagnosis was recorded. RESULTS: The average …
Inappropriate comparisons of incidence and prevalence in epidemiologic research
Several epidemiologists have published papers in major medical journals in which they compare incidence rates and prevalence and use these comparisons to support conclusions regarding questions of major public health importance. Although these papers have been criticized in published correspondence, we believe that continued use and advocacy of such comparisons by some epidemiologists has created the need for a full discussion of this practice. I…
Risk factors for self-reported uterine fibroids
To identify risk factors for uterine fibroids, a case-control design used to analyze data from control subjects enrolled in the Cancer and Steroid Hormone Study. Case patients were 201 women who reported a history of uterine fibroids, and control subjects were 1503 women without fibroids, individually matched by age to case patients. Reporting of fibroids was more frequent among premenopausal women, women who had frequent Papanicolaou (Pap) smear…
A comparison of estrogen and progesterone receptors in black and white breast cancer patients
After standardization for age and menopausal status, the prevalence of estrogen receptor positivity among 88 White breast cancer patients was about .72 compared with a prevalence of about .54 among Black patients. The prevalence of progesterone receptor positivity was also higher among White than among Black patients, although the magnitude of the difference was smaller. These differences were unchanged after adjustment for tumor size and nodal a…
Occupational risk for laryngeal cancer
In a case-control analysis, we studied the effects of type of employment on laryngeal cancer risk using the interview data from the Third National Cancer Survey. Effects were measured relative to the risk for those employed in a group of arbitrarily defined industries and occupations with low risk. We excluded females and controlled for age, tobacco use, alcohol use, and race in the analysis. We found ratio estimates above 3.0 for workers in the …
Differences in Heat-Related Mortality by Citizenship Status
Objectives. To determine whether non-US citizens have a higher mortality risk of heat-related deaths than do US citizens. Methods. We used place of residence reported in mortality data from the National Vital Statistics System from 2005 to 2014 as a proxy for citizenship to examine differences in heat-related deaths between non-US and US citizens. Estimates from the US Census Bureau American Community Survey of self-reported citizenship status an…
Brain cancer and nonoccupational risk factors
In a nested case-control study of nuclear workers, 82 brain cancer cases were compared with 328 matched controls to investigate the possible association with nonoccupational risk factors such as histories of epilepsy or head injury. We observed a moderately strong association between brain cancer occurrence and history of epilepsy (OR = 5.7, 95 per cent CI: 1.0, 32.1), but did not find a positive association with previous head injury (OR = 0.9, 9…
Occupational risk for laryngeal cancer
In a case-control analysis, we studied the effects of type of employment on laryngeal cancer risk using the interview data from the Third National Cancer Survey. Effects were measured relative to the risk for those employed in a group of arbitrarily defined industries and occupations with low risk. We excluded females and controlled for age, tobacco use, alcohol use, and race in the analysis. We found ratio estimates above 3.0 for workers in the …
Brain cancer and nonoccupational risk factors
In a nested case-control study of nuclear workers, 82 brain cancer cases were compared with 328 matched controls to investigate the possible association with nonoccupational risk factors such as histories of epilepsy or head injury. We observed a moderately strong association between brain cancer occurrence and history of epilepsy (OR = 5.7, 95 per cent CI: 1.0, 32.1), but did not find a positive association with previous head injury (OR = 0.9, 9…
A comparison of estrogen and progesterone receptors in black and white breast cancer patients
After standardization for age and menopausal status, the prevalence of estrogen receptor positivity among 88 White breast cancer patients was about .72 compared with a prevalence of about .54 among Black patients. The prevalence of progesterone receptor positivity was also higher among White than among Black patients, although the magnitude of the difference was smaller. These differences were unchanged after adjustment for tumor size and nodal a…
Inappropriate comparisons of incidence and prevalence in epidemiologic research
Several epidemiologists have published papers in major medical journals in which they compare incidence rates and prevalence and use these comparisons to support conclusions regarding questions of major public health importance. Although these papers have been criticized in published correspondence, we believe that continued use and advocacy of such comparisons by some epidemiologists has created the need for a full discussion of this practice. I…
Does increased detection account for the rising incidence of breast cancer
BACKGROUND: The incidence of breast cancer has been increasing over time in the United States. METHODS: To determine the role of screening in this increase, trends in the incidence of in situ and invasive carcinoma of the breast were evaluated using records of the metropolitan Atlanta SEER program between 1979 and 1986. From a sample of records, evidence of symptoms and mammographic screening prior to diagnosis was recorded. RESULTS: The average …
Demographic predictors of mammography and Pap smear screening in US women
OBJECTIVES. Proven screening technologies exist for both breast and cervical cancer, but they are underused by many women. We sought to evaluate the effect of demographic characteristics on the underuse of mammography and Pap smear screening. METHODS. We analyzed responses from 12,252 women who participated in the 1987 National Health Interview Survey Cancer Control Supplement. Demographic profiles were produced to target severely underserved gro…
Excess mortality among cigarette smokers
OBJECTIVES: This study was undertaken to examine changes in smoking-specific death rates from the 1960s to the 1980s. METHODS: In two prospective studies, one from 1959 to 1965 and the other from 1982 to 1988, death rates from lung cancer, coronary heart disease, and other major smoking-related diseases were measured among more than 200,000 current smokers and 480,000 lifelong non-smokers in each study. RESULTS: From the first to the second study…
Heat-Related Deaths during the July 1995 Heat Wave in Chicago
During a record-setting heat wave in Chicago in July 1995, there were at least 700 excess deaths, most of which were classified as heat-related. We sought to determine who was at greatest risk for heat-related death.
Risk factors for self-reported uterine fibroids
To identify risk factors for uterine fibroids, a case-control design used to analyze data from control subjects enrolled in the Cancer and Steroid Hormone Study. Case patients were 201 women who reported a history of uterine fibroids, and control subjects were 1503 women without fibroids, individually matched by age to case patients. Reporting of fibroids was more frequent among premenopausal women, women who had frequent Papanicolaou (Pap) smear…
Método modificado de muestreo por conglomerados para la evaluación rápida de necesidades después de un desastre
El método de muestreo por conglomerados puede utilizarse para llevar a cabo la evaluación rápida de las necesidades de salud y de otro tipo en comunidades afectadas por desastres naturales. El método, que se basa en el modelo usado por el Programa Ampliado de Inmunización de la OMS para estimar la cobertura con vacunación, ha sido modificado para que proporcione 1) estimaciones de la población que queda en una zona determinada y 2) estimaciones d…
High-Intensity Targeted Screening for Elevated Blood Lead Levels Among Children in 2 Inner-City Chicago Communities
Objectives. We assessed the prevalence of elevated blood lead levels (≥ 10 micrograms of lead per deciliter of blood), risk factors, and previous blood lead testing among children in 2 high-risk Chicago, Ill, communities. Methods. Through high-intensity targeted screening, blood lead levels were tested and risks were assessed among a representative sample of children aged 1 to 5 years who were at risk for lead exposure. Results. Of the 539 childr…
Associations of Maternal Age- and Parity-Related Factors With Trends in Low-Birthweight Rates
Objectives. We assessed the effects of changes in the maternal age–parity distribution and age-and parity-specific low-birthweight rates on low-birthweight trends in the United States. Methods. We used natality file data from 1980 through 2000 to assess very-low-birthweight and low-birthweight rates among singleton live-born infants. Results. Changes in age-and parity-specific low-birthweight rates were the main contributor to the overall trend i…
Yang Et Al. Respond
We thank Schempf and Becker for pointing out a deficiency in our presentation, although we disagree with their solution. In fact, we were aware of the alternative standards they cite and rejected them as inappropriate. Although researchers are often taught otherwise, the choice of standard distributions is not arbitrary and should not be based on symmetry or other mathematical considerations. Rather, the choice of standard distribution should be …
The issue of confounding in epidemiological studies of ambient air pollution and pregnancy outcomes
BACKGROUND: Relationships between ambient air pollution levels during pregnancy and adverse pregnancy outcomes have been investigated using one of three analytic approaches: ambient pollution levels have been contrasted over space, time or both space and time. Although the three approaches share a common goal, to estimate the causal effects of pollution on pregnancy outcomes, they face different challenges with respect to confounding. METHODS: A …
Race, neighbourhood characteristics and disparities in chemotherapy for colorectal cancer
BACKGROUND: Studies have found significant race/ethnic and age differences in receipt of adjuvant chemotherapy for stages III colon and II/III rectal cancers. Little is known about the role of neighbourhood factors in these disparities. METHODS: The 4748 Black and White patients from the Georgia Comprehensive Cancer Registry were diagnosed with stages III colon and II/III rectal cancers between 2000 and 2004. Neighbourhood poverty, segregation (%…
Added Sugar Intake and Cardiovascular Diseases Mortality Among US Adults
IMPORTANCE Epidemiologic studies have suggested that higher intake of added sugar is associated with cardiovascular disease (CVD) risk factors. Few prospective studies have examined the association of added sugar intake with CVD mortality. OBJECTIVE To examine time trends of added sugar consumption as percentage of daily calories in the United States and investigate the association of this consumption with CVD mortality. DESIGN, SETTING, AND PART…
Association Between Birthplace and Current Asthma
Objectives. We evaluated associations between current asthma and birthplace among major racial/ethnic groups in the United States. Methods. We used multivariate logistic regression methods to analyze data on 102 524 children and adolescents and 255 156 adults in the National Health Interview Survey (2001–2009). Results. We found significantly higher prevalence (P Conclusions. Current asthma status was positively associated with being born in the …
Mental Health of Transgender and Gender Nonconforming Youth Compared With Their Peers
BACKGROUND: Understanding the magnitude of mental health problems, particularly life-threatening ones, experienced by transgender and/or gender nonconforming (TGNC) youth can lead to improved management of these conditions. METHODS: Electronic medical records were used to identify a cohort of 588 transfeminine and 745 transmasculine children (3-9 years old) and adolescents (10-17 years old) enrolled in integrated health care systems in California…
Differences in Heat-Related Mortality by Citizenship Status
Objectives. To determine whether non-US citizens have a higher mortality risk of heat-related deaths than do US citizens. Methods. We used place of residence reported in mortality data from the National Vital Statistics System from 2005 to 2014 as a proxy for citizenship to examine differences in heat-related deaths between non-US and US citizens. Estimates from the US Census Bureau American Community Survey of self-reported citizenship status an…
Evaluation of a Novel Ambient Light Survey Question in the Cancer Prevention Study-3
Nighttime light exposure may increase cancer risk by disrupting the circadian system. However, there is no well-established survey method for measuring ambient light. In the Cancer Prevention Study-3, 732 men and women answered a light survey based on seven environments. The light environment in the past year was assessed twice, one year apart, and four one-week diaries were collected between the annual surveys. A total of 170 participants wore a…
Medicine (18 works) · Demography (15 works) · Environmental health (12 works) · Internal Medicine (11 works) · Internal Medicine (9 works) · Cancer (7 works) · Gerontology (6 works) · Confidence interval (5 works) · Population (5 works) · Sociology (5 works)